All Stories

  1. Age and sex influence transcriptomic responses to statin therapy that control liver aging during systemic metabolic dysfunction

    Article • Hepatology, February 2026, Wolters Kluwer Health

    Liuyang Wang

  2. Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure

    Article • Gut, January 2026, BMJ

    Liuyang Wang

  3. Causal splicing variants revealed by deep-learning integration of single-cell sQTL mapping under influenza infection

    Article • January 2026, Springer Science + Business Media

    Liuyang Wang

  4. Transcriptional mechanisms of sex-biased gene expression and their connections to disease-associated variation

    Article • Human Molecular Genetics, January 2026, Oxford University Press (OUP)

    Liuyang Wang

  5. Paired single-cell and spatial transcriptional profiling reveals a central osteopontin macrophage response mediating tuberculous granuloma formation

    Article • mBio, September 2025, ASM Journals

    Liuyang Wang

  6. Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis

    Article • Cell Genomics, September 2025, Elsevier

    Liuyang Wang

  7. Author Correction: Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction

    Article • Nature Communications, May 2025, Springer Science + Business Media

    Liuyang Wang

  8. Context-specific eQTLs provide deeper insight into causal genes underlying shared genetic architecture of COVID-19 and idiopathic pulmonary fibrosis

    Article • Human Genetics and Genomics Advances, April 2025, Elsevier

    Liuyang Wang

  9. Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction

    Article • Nature Communications, March 2025, Springer Science + Business Media

    Liuyang Wang

  10. Immunomodulation of T cell-mediated alloimmunity by proximity to endothelial cells under the mammalian target of rapamycin blockade

    Article • Arabian archaeology and epigraphy, February 2025, Elsevier

    Liuyang Wang

  11. B-Lightning: using bait genes for marker gene hunting in single-cell data with complex heterogeneity

    Article • Briefings in Bioinformatics, November 2024, Oxford University Press (OUP)

    Liuyang Wang

  12. Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response

    Article • Nature Communications, October 2024, Springer Science + Business Media

    Liuyang Wang

  13. The senescence-associated secretome of Hedgehog-deficient hepatocytes drives MASLD progression

    Article • Journal of Clinical Investigation, August 2024, American Society for Clinical Investigation

    Liuyang Wang

  14. Aging promotes metabolic dysfunction-associated steatotic liver disease by inducing ferroptotic stress

    Article • Nature Aging, June 2024, Springer Science + Business Media

    Liuyang Wang

  15. SifiNet: a robust and accurate method to identify feature gene sets and annotate cells

    Article • Nucleic Acids Research, April 2024, Oxford University Press (OUP)

    Liuyang Wang

  16. Breaking NGF–TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection

    Article • Nature Immunology, January 2024, Springer Science + Business Media

    Liuyang Wang

  17. Targeting intratumor heterogeneity suppresses colorectal cancer chemoresistance and metastasis

    Article • EMBO Reports, June 2023, Springer Science + Business Media

    Liuyang Wang

  18. The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

    Article • eLife, June 2023, eLife

    Liuyang Wang

  19. Antagonizing the irreversible thrombomodulin-initiated proteolytic signaling alleviates age-related liver fibrosis via senescent cell killing

    Article • BDJ, May 2023, Springer Science + Business Media

    Liuyang Wang

  20. Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation

    Article • Cell Genomics, May 2023, Elsevier

    Liuyang Wang

  21. Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression

    Article • Hepatology, April 2023, Wolters Kluwer Health

    Liuyang Wang

  22. Clustering Deviation Index (CDI): a robust and accurate internal measure for evaluating scRNA-seq data clustering

    Article • Genome Biology, December 2022, Springer Science + Business Media

    Liuyang Wang

  23. GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in C. elegans

    Article • Science Advances, December 2022, American Association for the Advancement of Science

    Liuyang Wang

  24. The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction

    Article • Cell Host & Microbe, December 2022, Elsevier

    Liuyang Wang

  25. Single-cell genome-wide association reveals that a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus

    Article • Cell Genomics, November 2022, Elsevier

    Liuyang Wang

  26. Editorial: Bioinformatics tools (and web server) for cancer biomarker development, volume II

    Article • Frontiers in Genetics, October 2022, Frontiers

    Liuyang Wang

  27. Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions

    Article • mBio, June 2022, ASM Journals

    Liuyang Wang

  28. Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy

    Article • Cancer Cell, June 2022, Elsevier

    Liuyang Wang

  29. Data from: Single-cell genome-wide association reveals a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus

    Article • January 2022, Duke University Libraries

    Liuyang Wang

  30. Human genetic diversity regulating the TLR10/TLR1/TLR6 locus confers increased cytokines in response to Chlamydia trachomatis

    Article • Human Genetics and Genomics Advances, January 2022, Elsevier

    Liuyang Wang

  31. Trav15-dv6 family Tcrd rearrangements diversify the Tcra repertoire

    Article • Journal of Experimental Medicine, December 2021, Rockefeller University Press

    Liuyang Wang

  32. Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor

    Article • PLoS Neglected Tropical Diseases, October 2021, PLOS

    Liuyang Wang

  33. ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice

    Article • PLoS Pathogens, July 2021, PLOS

    Liuyang Wang

  34. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

    Article • Genome Medicine, May 2021, Springer Science + Business Media

    Liuyang Wang

  35. Resident memory T cells in tumor-distant tissues fortify against metastasis formation

    Article • Cell Reports, May 2021, Elsevier

    Liuyang Wang

  36. TCR repertoire characteristics predict clinical response to adoptive CTL therapy against nasopharyngeal carcinoma

    Article • OncoImmunology, January 2021, Taylor & Francis

    Liuyang Wang

  37. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

    Article • December 2020, Cold Spring Harbor Laboratory Press

    Liuyang Wang

  38. Modeling of variables in cellular infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease

    Article • Scientific Reports, October 2020, Springer Science + Business Media

    Liuyang Wang

  39. Editorial: Bioinformatics Tools (and Web Server) for Cancer Biomarker Development

    Article • Frontiers in Oncology, October 2020, Frontiers

    Liuyang Wang

  40. Comparative Genomic Analysis Reveals the Mechanism Driving the Diversification of Plastomic Structure in Taxaceae Species

    Article • Frontiers in Genetics, January 2020, Frontiers

    Liuyang Wang

  41. T cell receptor repertoire as a prognosis marker for heat shock protein peptide complex-96 vaccine trial against newly diagnosed glioblastoma

    Article • OncoImmunology, January 2020, Taylor & Francis

    Liuyang Wang

  42. A real-time PCR assay for quantification of parasite burden in murine models of leishmaniasis

    Article • PeerJ, November 2018, PeerJ

    Liuyang Wang

  43. Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin

    Article • Nature Chemical Biology, August 2018, Springer Science + Business Media

    Liuyang Wang

  44. An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease

    Article • Cell Host & Microbe, August 2018, Elsevier

    Liuyang Wang

  45. Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10

    Article • Cell Reports, June 2018, Elsevier

    Liuyang Wang

  46. Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility

    Article • PLOS One, May 2018, PLOS

    Liuyang Wang

  47. Adaptive Transcriptome Profiling of Subterranean Zokor, Myospalax baileyi, to High- Altitude Stresses in Tibet

    Article • Scientific Reports, March 2018, Nature

    Liuyang Wang

  48. Correction to Supporting Information for Alvarez et al., Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol

    Article • Proceedings of the National Academy of Sciences, November 2017, Proceedings of the National Academy of Sciences

    Liuyang Wang

  49. Correction for Alvarez et al., Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol

    Article • Proceedings of the National Academy of Sciences, November 2017, Proceedings of the National Academy of Sciences

    Liuyang Wang

  50. Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol

    Article • Proceedings of the National Academy of Sciences, August 2017, Proceedings of the National Academy of Sciences

    Liuyang Wang

  51. Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination

    Article • PLoS Biology, August 2017, PLOS

    Liuyang Wang

  52. Composite measures of selection can improve the signal-to-noise ratio in genome scans

    Article • Methods in Ecology and Evolution, June 2017, Wiley

    Liuyang Wang

  53. Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis

    Article • Science Advances, March 2017, American Association for the Advancement of Science

    Liuyang Wang

  54. Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk

    Article • Cell, March 2017, Elsevier

    Liuyang Wang

  55. A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation

    Article • European Journal of Biochemistry, January 2017, Wiley

    Liuyang Wang

  56. minotaur: A platform for the analysis and visualization of multivariate results from genome scans with R Shiny

    Article • Molecular Ecology Resources, August 2016, Wiley

    Liuyang Wang

  57. The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

    Article • PLoS Pathogens, July 2016, PLOS

    Liuyang Wang

  58. Sympatric speciation of spiny mice, Acomys , unfolded transcriptomically at Evolution Canyon, Israel

    Article • Proceedings of the National Academy of Sciences, July 2016, Proceedings of the National Academy of Sciences

    Liuyang Wang

  59. Transcriptome, genetic editing, and microRNA divergence substantiate sympatric speciation of blind mole rat, Spalax

    Article • Proceedings of the National Academy of Sciences, June 2016, Proceedings of the National Academy of Sciences

    Liuyang Wang

  60. Contribution to Virulence of a Novel Anti-inflammatory Effector in Salmonella enterica

    Article • Open Forum Infectious Diseases, December 2015, Oxford University Press (OUP)

    Liuyang Wang

  61. CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation

    Article • September 2015, Springer Science + Business Media

    Dr David M Tobin, Liuyang Wang

  62. A Bayesian Approach to Inferring Rates of Selfing and Locus-Specific Mutation

    Article • Genetics, September 2015, Genetics Society of America

    Liuyang Wang, Dr Andrey Tatarenkov

  63. Expression Divergence of Duplicate Genes in the Protein Kinase Superfamily in Pacific Oyster

    Article • Evolutionary Bioinformatics, September 2015, Libertas Academica, Ltd.

    Liuyang Wang

  64. Comparative analyses of clinical and environmental populations ofCryptococcus neoformansin Botswana

    Article • Molecular Ecology, July 2015, Wiley

    Liuyang Wang

  65. De Novo Transcriptome Assembly and Development of Novel Microsatellite Markers for the Traditional Chinese Medicinal Herb, Veratrilla baillonii Franch (Gentianaceae)

    Article • Evolutionary Bioinformatics, July 2015, Libertas Academica, Ltd.

    Liuyang Wang

  66. RNA-seq Reveals Complicated Transcriptomic Responses to Drought Stress in a Nonmodel Tropic Plant, Bombax ceiba L.

    Article • Evolutionary Bioinformatics, June 2015, Libertas Academica, Ltd.

    Liuyang Wang

  67. Refugial isolation and range expansions drive the genetic structure of Oxyria sinensis (Polygonaceae) in the Himalaya-Hengduan Mountains

    Article • Scientific Reports, May 2015, Nature

    Liuyang Wang

  68. Functional Organization of the Genome May Shape the Species Boundary in the House Mouse

    Article • Molecular Biology and Evolution, January 2015, Oxford University Press (OUP)

    Liuyang Wang

  69. RNA: An Expanding View of Function and Evolution

    Article • Evolutionary Bioinformatics, January 2015, SAGE Publications

    Liuyang Wang

  70. The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus

    Article • Mammalian Genome, February 2014, Springer Science + Business Media

    Liuyang Wang

  71. Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone betweenMus musculus musculusandM. m. domesticus

    Article • Molecular Ecology, May 2012, Wiley

    Liuyang Wang

  72. Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone

    Article • Molecular Ecology, June 2011, Wiley

    Liuyang Wang

  73. Evolutionary history of an alpine shrub Hippophae tibetana (Elaeagnaceae): allopatric divergence and regional expansion

    Article • Biological Journal of the Linnean Society, November 2010, Oxford University Press (OUP)

    Liuyang Wang

  74. Allopatric divergence and phylogeographic structure of the plateau zokor (Eospalax baileyi), a fossorial rodent endemic to the Qinghai-Tibetan Plateau

    Article • Journal of Biogeography, April 2010, Wiley

    Liuyang Wang

  75. Phylogeographic analyses suggest that a deciduous species (Ostryopsis davidianaDecne., Betulaceae) survived in northern China during the Last Glacial Maximum

    Article • Journal of Biogeography, November 2009, Wiley

    Liuyang Wang

  76. cDNA Library Construction and Expressed Sequence Tags(ESTs) Analyses of an Alpine Plant Species Gentiana officinalis(Gentianaceae)

    Article • Acta Botanica Yunnanica, August 2009, China Science Publishing & Media Ltd.

    Liuyang Wang

  77. Repeated Range Expansion and Glacial Endurance ofPotentilla glabra(Rosaceae) in the Qinghai-Tibetan Plateau

    Article • Journal of Integrative Plant Biology, July 2009, Wiley

    Liuyang Wang

  78. Development and characterization of novel microsatellite markers isolated from Potentilla fruticosa L. (Rosaceae), and cross-species amplification in its sister species—Potentilla glabra L.

    Article • Conservation Genetics Resources, May 2009, Springer Science + Business Media

    Liuyang Wang

  79. History and evolution of alpine plants endemic to the Qinghai-Tibetan Plateau:Aconitum gymnandrum(Ranunculaceae)

    Article • Molecular Ecology, February 2009, Wiley

    Liuyang Wang

  80. Confirmation of natural hybrids between Gentiana straminea and G. siphonantha (Gentianaceae) based on molecular evidence

    Article • Frontiers of Biology in China, June 2008, Springer Science + Business Media

    Liuyang Wang

  81. Genetic variation in the endangered Anisodus tanguticus (Solanaceae), an alpine perennial endemic to the Qinghai-Tibetan Plateau

    Article • Genetica, May 2007, Springer Science + Business Media

    Liuyang Wang

  82. Linkage disequilibrium approaches for detecting hybrid zone movement

    Article • Cambridge University Press

    Liuyang Wang