All Stories

  1. Atrial Myopathy and Heart Failure: Immunomolecular Mechanisms and Clinical Implications

    Article • International Journal of Molecular Sciences, August 2025, MDPI AG

    Lisardo Bosca

  2. Correction: Povo-Retana et al. Trabectedin and Lurbinectedin Modulate the Interplay between Cells in the Tumour Microenvironment—Progresses in Their Use in Combined Cancer Therapy. Molecules 2024, 29, 331

    Article • Molecules, June 2025, MDPI AG

    Lisardo Bosca

  3. Potential Beneficial Role of Nitric Oxide in SARS-CoV-2 Infection: Beyond Spike-Binding Inhibition

    Article • Antioxidants, October 2024, MDPI AG

    Lisardo Bosca

  4. Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington’s disease

    Article • Proceedings of the National Academy of Sciences, September 2024, Proceedings of the National Academy of Sciences

    Tapas Hazra, Lisardo Bosca

  5. Endogenous LXR signaling controls pulmonary surfactant homeostasis and prevents lung inflammation

    Article • Cellular and Molecular Life Sciences, July 2024, Springer Science + Business Media

    Lisardo Bosca

  6. Role of NOD1 in atrial myopathy associated with heart failure

    Article • Cardiovascular Research, May 2024, Oxford University Press (OUP)

    Lisardo Bosca

  7. Sex differences in cardiac ferroptosis after acute myocardial infarction in wild type and aryl hydrocarbon receptor knockout mice

    Article • Cardiovascular Research, May 2024, Oxford University Press (OUP)

    Lisardo Bosca

  8. Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses

    Article • Advanced Science, March 2024, Wiley

    Zhiqiang Huang, Lisardo Bosca

  9. Biomarkers in Contrast-Induced Acute Kidney Injury: Towards A New Perspective

    Article • International Journal of Molecular Sciences, March 2024, MDPI AG

    Lisardo Bosca

  10. Biomarkers in Contrast-Induced Acute Kidney Injury: Towards a new perspective.

    Article • February 2024, MDPI AG

    Lisardo Bosca

  11. Contribution of Nucleotide-Binding Oligomerization Domain-like (NOD) Receptors to the Immune and Metabolic Health

    Article • Biomedicines, February 2024, MDPI AG

    Lisardo Bosca

  12. Trabectedin and Lurbinectedin Modulate the Interplay between Cells in the Tumour Microenvironment—Progresses in Their Use in Combined Cancer Therapy

    Article • Molecules, January 2024, MDPI AG

    Lisardo Bosca

  13. Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver

    Article • Frontiers in Endocrinology, December 2023, Frontiers

    Lisardo Bosca

  14. 3,4-dimethoxychalcone induces autophagy and reduces neointimal hyperplasia and aortic lesions in mouse models of atherosclerosis

    Article • Cell Death and Disease, November 2023, Springer Science + Business Media

    Lisardo Bosca

  15. Lipoxin-mediated signaling: ALX/FPR2 interaction and beyond

    Article • Pharmacological Research, November 2023, Elsevier

    Lisardo Bosca

  16. Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity

    Article • Frontiers in Immunology, August 2023, Frontiers

    Lisardo Bosca

  17. Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance

    Article • JHEP Reports, August 2023, Elsevier

    Lisardo Bosca

  18. Defining the metabolic signatures associated with human macrophage polarisation

    Article • Biochemical Society Transactions, July 2023, Portland Press Ltd.

    Lisardo Bosca

  19. Editorial: Women in gastrointestinal cancers, volume II: 2022

    Article • Frontiers in Oncology, May 2023, Frontiers

    Lisardo Bosca

  20. Trabectedin modulates macrophage polarization in the tumor-microenvironment. Role of KV1.3 and KV1.5 channels

    Article • Biomedicine & Pharmacotherapy, May 2023, Elsevier

    Lisardo Bosca

  21. Crosstalk between P2Y receptors and cyclooxygenase activity in inflammation and tissue repair

    Article • Purinergic Signalling, April 2023, Springer Science + Business Media

    Lisardo Bosca

  22. Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB

    Article • Cellular and Molecular Life Sciences, March 2023, Springer Science + Business Media

    Lisardo Bosca

  23. Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: Relevance for their antitumor activity

    Article • March 2023, Springer Science + Business Media

    Lisardo Bosca

  24. Beneficial effect of TLR4 blockade by a specific aptamer antagonist after acute myocardial infarction

    Article • Biomedicine & Pharmacotherapy, February 2023, Elsevier

    Lisardo Bosca

  25. Free triiodothyronine levels and age influences the metabolic profile and COVID-19 severity parameters in euthyroid and levothyroxine-treated patients

    Article • Frontiers in Endocrinology, November 2022, Frontiers

    Lisardo Bosca

  26. Quantitative Proteomics Analysis Reveals That Cyclooxygenase-2 Modulates Mitochondrial Respiratory Chain Complex IV in Cardiomyocytes

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Lisardo Bosca

  27. Unraveling the interplay between iron homeostasis, ferroptosis and extramedullary hematopoiesis

    Article • Pharmacological Research, September 2022, Elsevier

    Lisardo Bosca

  28. COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury

    Article • Antioxidants, August 2022, MDPI AG

    Lisardo Bosca

  29. Functional Crosstalk between PCSK9 Internalization and Pro-Inflammatory Activation in Human Macrophages: Role of Reactive Oxygen Species Release

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Lisardo Bosca

  30. High-fat diet activates splenic NOD1 and enhances neutrophil recruitment and neutrophil extracellular traps release in the spleen of ApoE-deficient mice

    Article • Cellular and Molecular Life Sciences, July 2022, Springer Science + Business Media

    Lisardo Bosca

  31. Specialized Proresolving Mediators Protect Against Experimental Autoimmune Myocarditis by Modulating Ca2+ Handling and NRF2 Activation

    Article • JACC Basic to Translational Science, June 2022, Elsevier

    Lisardo Bosca

  32. Use of 11C-acetate PET imaging in the evaluation of advanced atherogenic lesions

    Article • Journal of Nuclear Cardiology, June 2022, Elsevier

    Lisardo Bosca

  33. The Aryl Hydrocarbon Receptor Ligand FICZ Improves Left Ventricular Remodeling and Cardiac Function at the Onset of Pressure Overload-Induced Heart Failure in Mice

    Article • International Journal of Molecular Sciences, May 2022, MDPI AG

    Lisardo Bosca

  34. NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions

    Article • Biomedicine & Pharmacotherapy, April 2022, Elsevier

    Lisardo Bosca

  35. High Fat Diet Activates Splenic NOD1 and Enhances Neutrophil Recruitment and Neutrophil Extracellular Traps Release in the Spleen of ApoE-Deficient Mice

    Article • February 2022, Springer Science + Business Media

    Lisardo Bosca

  36. Immuno-Modulation to Treat Common Cardiovascular Diseases

    Article • Journal of the American College of Cardiology, February 2022, Elsevier

    Lisardo Bosca

  37. Graphene Particles Interfere with Pro‐Inflammatory Polarization of Human Macrophages: Functional and Electrophysiological Evidence

    Article • Advanced Biology, September 2021, Wiley

    Lisardo Bosca

  38. NOD1 in the interplay between microbiota and gastrointestinal immune adaptations

    Article • Pharmacological Research, September 2021, Elsevier

    Lisardo Bosca

  39. Beyond classic concepts in thyroid homeostasis: Immune system and microbiota

    Article • Molecular and Cellular Endocrinology, August 2021, Elsevier

    Lisardo Bosca

  40. Crosstalk Between LXR and Caveolin-1 Signaling Supports Cholesterol Efflux and Anti-Inflammatory Pathways in Macrophages

    Article • Frontiers in Endocrinology, May 2021, Frontiers

    Lisardo Bosca

  41. NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health

    Article • Biomedicines, May 2021, MDPI AG

    Lisardo Bosca

  42. Resolution-Based Therapies: The Potential of Lipoxins to Treat Human Diseases

    Article • Frontiers in Immunology, April 2021, Frontiers

    Lisardo Bosca

  43. Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress

    Article • Aging, March 2021, Impact Journals, LLC

    Lisardo Bosca

  44. Contribution of Extramedullary Hematopoiesis to Atherosclerosis. The Spleen as a Neglected Hub of Inflammatory Cells

    Article • Frontiers in Immunology, October 2020, Frontiers

    Lisardo Bosca

  45. Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate—Novel Insights

    Article • Cancers, October 2020, MDPI AG

    Lisardo Bosca

  46. Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis

    Article • Cells, September 2020, MDPI AG

    Prof. Vicente Andrés, Lisardo Bosca, Jose Martinez Gonzalez

  47. NOD1 deficiency promotes an imbalance of thyroid hormones and microbiota homeostasis in mice fed high fat diet

    Article • Scientific Reports, July 2020, Springer Science + Business Media

    Lisardo Bosca

  48. Inflammation in Parkinson’s Disease: Mechanisms and Therapeutic Implications

    Article • Cells, July 2020, MDPI AG

    Lisardo Bosca

  49. Innate Immune Receptors, Key Actors in Cardiovascular Diseases

    Article • JACC Basic to Translational Science, July 2020, Elsevier

    Lisardo Bosca

  50. BML‐111 treatment prevents cardiac apoptosis and oxidative stress in a mouse model of autoimmune myocarditis

    Article • The FASEB Journal, June 2020, Wiley

    Lisardo Bosca

  51. GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity

    Article • Cellular and Molecular Life Sciences, January 2020, Springer Science + Business Media

    Lisardo Bosca

  52. Tumor stem cells fuse with monocytes to form highly invasive tumor-hybrid cells

    Article • OncoImmunology, January 2020, Taylor & Francis

    Lisardo Bosca

  53. CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform): A multicenter preclinical network for testing reproducibility in cardiovascular interventions

    Article • Scientific Reports, December 2019, Springer Science + Business Media

    Lisardo Bosca, Dr Francisco Miguel Sánchez Margallo

  54. Transition of Macrophages to Fibroblast-Like Cells in Healing Myocardial Infarction

    Article • Journal of the American College of Cardiology, December 2019, Elsevier

    Lisardo Bosca

  55. Self-defense of macrophages against oxidative injury: Fighting for their own survival

    Article • Redox Biology, September 2019, Elsevier

    Lisardo Bosca

  56. Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality

    Article • Frontiers in Cellular Neuroscience, April 2019, Frontiers

    Lisardo Bosca

  57. LXR Signaling Regulates Macrophage Survival and Inflammation in Response to Ionizing Radiation

    Article • International Journal of Radiation Oncology*Biology*Physics, March 2019, Elsevier

    Lisardo Bosca

  58. Protective Role of Hepatocyte Cyclooxygenase-2 Expression Against Liver Ischemia-Reperfusion Injury in Mice

    Article • Hepatology, February 2019, Wiley

    Lisardo Bosca

  59. Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort

    Article • World Journal of Gastroenterology, January 2019, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Lisardo Bosca

  60. Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages

    Article • Molecular and Cellular Biology, January 2019, ASM Journals

    Lisardo Bosca

  61. Post-translational modifications of prostaglandin-endoperoxide synthase 2 in colorectal cancer: An update

    Article • World Journal of Gastroenterology, December 2018, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Lisardo Bosca

  62. Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM‐1

    Article • The FASEB Journal, November 2018, Wiley

    Dr Paloma Martin-Sanz, Dr Cristina Rodriguez, Silvia Gonzalez-Ramos, Miguel Angel Lasuncion, Prof. Vicente Andrés, Lisardo Bosca

  63. Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells

    Article • Frontiers in Oncology, August 2018, Frontiers

    Lisardo Bosca

  64. The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.

    Article • Journal of Biological Chemistry, July 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  65. Protection against gamma-radiation injury by protein tyrosine phosphatase 1B

    Article • Redox Biology, July 2018, Elsevier

    Lisardo Bosca

  66. Deficiency of NOD1 Improves the β-Adrenergic Modulation of Ca2+ Handling in a Mouse Model of Heart Failure

    Article • Frontiers in Physiology, June 2018, Frontiers

    Lisardo Bosca

  67. Correction: Induction of nitric oxide synthase-2 proceeds with the concomitant downregulation of the endogenous caveolin levels (doi:10.1242/jcs.01002)

    Article • Journal of Cell Science, May 2018, The Company of Biologists

    Lisardo Bosca

  68. PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, February 2018, Elsevier

    Lisardo Bosca

  69. GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr−/− mice

    Article • International Journal of Obesity, January 2018, Springer Science + Business Media

    Lisardo Bosca

  70. Prostaglandin E2 Impairs P2Y2/P2Y4 Receptor Signaling in Cerebellar Astrocytes via EP3 Receptors

    Article • Frontiers in Pharmacology, December 2017, Frontiers

    Lisardo Bosca

  71. Expression of Concern: Induction of nitric oxide synthase-2 proceeds with the concomitant downregulation of the endogenous caveolin levels. J. Cell Sci. doi: 10.1242/jcs.01002

    Article • Journal of Cell Science, August 2017, The Company of Biologists

    Lisardo Bosca

  72. Mild and Short-Term Caloric Restriction Prevents Obesity-Induced Cardiomyopathy in Young Zucker Rats without Changing in Metabolites and Fatty Acids Cardiac Profile

    Article • Frontiers in Physiology, February 2017, Frontiers

    Lisardo Bosca, Encarnacion Fernandez-Valle

  73. Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives

    Article • World Journal of Gastroenterology, January 2017, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Lisardo Bosca

  74. Role of NOD1 in Heart Failure Progression via Regulation of Ca 2+ Handling

    Article • Journal of the American College of Cardiology, January 2017, Elsevier

    Lisardo Bosca

  75. Cell Expansion-Dependent Inflammatory and Metabolic Profile of Human Bone Marrow Mesenchymal Stem Cells

    Article • Frontiers in Physiology, November 2016, Frontiers

    Lisardo Bosca

  76. NOD1 activation in cardiac fibroblasts induces myocardial fibrosis in a murine model of type 2 diabetes

    Article • Biochemical Journal, November 2016, Portland Press Ltd.

    Lisardo Bosca

  77. Cyclooxygenase-2 expression in hepatocytes attenuates non-alcoholic steatohepatitis and liver fibrosis in mice

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, September 2016, Elsevier

    Lisardo Bosca

  78. New thiazolidinediones affect endothelial cell activation and angiogenesis

    Article • European Journal of Pharmacology, July 2016, Elsevier

    Lisardo Bosca

  79. GM-CSF Enhances Macrophage Glycolytic Activity In Vitro and Improves Detection of Inflammation In Vivo

    Article • Journal of Nuclear Medicine, April 2016, Society of Nuclear Medicine

    Lisardo Bosca

  80. New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr−/− mice

    Article • Pharmacological Research, February 2016, Elsevier

    Lisardo Bosca

  81. Activation of autophagy in macrophages by pro-resolving lipid mediators

    Article • Autophagy, August 2015, Taylor & Francis

    Lisardo Bosca

  82. New indole-thiazolidine attenuates atherosclerosis in LDLr−/− mice

    Article • Vascular Pharmacology, August 2015, Elsevier

    Lisardo Bosca

  83. Metabolic signatures linked to macrophage polarization: from glucose metabolism to oxidative phosphorylation

    Article • Biochemical Society Transactions, August 2015, Portland Press Ltd.

    Lisardo Bosca

  84. Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer

    Article • Clinical Epigenetics, July 2015, Springer Science + Business Media

    Lisardo Bosca, Laia Pare

  85. HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

    Article • Arteriosclerosis Thrombosis and Vascular Biology, June 2015, Wolters Kluwer Health

    Lisardo Bosca

  86. Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling

    Article • Molecular and Cellular Biology, May 2015, ASM Journals

    Dr Paloma Martin-Sanz, Lisardo Bosca

  87. NOD1, a new player in cardiac function and calcium handling

    Article • Cardiovascular Research, March 2015, European Society of Cardiology

    Lisardo Bosca

  88. A labdane diterpene exerts ex vivo and in vivo cardioprotection against post-ischemic injury: Involvement of AKT-dependent mechanisms

    Article • Biochemical Pharmacology, February 2015, Elsevier

    Lisardo Bosca

  89. NOD1 receptor is up-regulated in diabetic human and murine myocardium

    Article • Clinical Science, December 2014, Portland Press Ltd.

    Lisardo Bosca

  90. Hepatic Cyclooxygenase-2 Expression Protects Against Diet-Induced Steatosis, Obesity, and Insulin Resistance

    Article • Diabetes, November 2014, American Diabetes Association

    Lisardo Bosca

  91. NFκB2/p100 Is a Key Factor for Endotoxin Tolerance in Human Monocytes: A Demonstration Using Primary Human Monocytes from Patients with Sepsis

    Article • The Journal of Immunology, September 2014, The American Association of Immunologists

    Lisardo Bosca

  92. Anti-inflammatory Actions of Acanthoic Acid-Related Diterpenes Involve Activation of the PI3K p110γ/δ Subunits and Inhibition of NF-κB

    Article • Chemistry & Biology, August 2014, Elsevier

    Lisardo Bosca

  93. P727Nucleotide-binding oligomerization domain-containing protein 1-signaling is upregulated in hearts from type 2 diabetic mice

    Article • Cardiovascular Research, June 2014, European Society of Cardiology

    Lisardo Bosca

  94. Mitochondrial DAMPs Induce Endotoxin Tolerance in Human Monocytes: An Observation in Patients with Myocardial Infarction

    Article • PLOS One, May 2014, PLOS

    Lisardo Bosca

  95. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

    Article • Cell Death and Disease, April 2014, Springer Science + Business Media

    Lisardo Bosca

  96. Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge

    Article • Cell Death and Disease, March 2014, Springer Science + Business Media

    Lisardo Bosca

  97. Involvement of monocytes/macrophages as key factors in the development and progression of cardiovascular diseases

    Article • Biochemical Journal, March 2014, Portland Press Ltd.

    Lisardo Bosca

  98. 2-deoxy-2-[18F]fluoro-d-mannose positron emission tomography imaging in atherosclerosis

    Article • Nature Medicine, January 2014, Springer Science + Business Media

    Lisardo Bosca

  99. Sustained Release of Prostaglandin E2in Fibroblasts Expressing Ectopically Cyclooxygenase 2 Impairs P2Y-Dependent Ca2+-Mobilization

    Article • Mediators of Inflammation, January 2014, Hindawi Publishing Corporation

    Lisardo Bosca

  100. Modulation of Voltage-Dependent and Inward Rectifier Potassium Channels by 15-Epi-Lipoxin-A4 in Activated Murine Macrophages: Implications in Innate Immunity

    Article • The Journal of Immunology, November 2013, The American Association of Immunologists

    Dr Carmen Valenzuela, Lisardo Bosca

  101. Regulation of 15-hydroxyprostaglandin dehydrogenase expression in hepatocellular carcinoma

    Article • The International Journal of Biochemistry & Cell Biology, November 2013, Elsevier

    Lisardo Bosca

  102. Progression of liver oncogenesis in the double transgenic mice c-myc/TGF α is not enhanced by cyclooxygenase-2 expression

    Article • Prostaglandins & Other Lipid Mediators, October 2013, Elsevier

    Lisardo Bosca

  103. Prolonged leptin treatment increases transient outward K+ current via upregulation of Kv4.2 and Kv4.3 channel subunits in adult rat ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, September 2013, Springer Science + Business Media

    Lisardo Bosca

  104. Selective Impairment of P2Y Signaling by Prostaglandin E2 in Macrophages: Implications for Ca2+-Dependent Responses

    Article • The Journal of Immunology, March 2013, The American Association of Immunologists

    Lisardo Bosca

  105. Identification of a novel Pfkfb1 mRNA variant in rat fetal liver

    Article • Biochemical and Biophysical Research Communications, February 2013, Elsevier

    Lisardo Bosca

  106. Cyclooxygenase-2 Is a Target of MicroRNA-16 in Human Hepatoma Cells

    Article • PLOS One, November 2012, PLOS

    Lisardo Bosca

  107. NOD1 Activation Induces Cardiac Dysfunction and Modulates Cardiac Fibrosis and Cardiomyocyte Apoptosis

    Article • PLOS One, September 2012, PLOS

    Lisardo Bosca

  108. Cardiotrophin-1 induces sarcoplasmic reticulum Ca2+ leak and arrhythmogenesis in adult rat ventricular myocytes

    Article • Cardiovascular Research, July 2012, European Society of Cardiology

    Lisardo Bosca

  109. Evaluation of epigenetic modulation of cyclooxygenase-2 as a prognostic marker for hepatocellular carcinoma

    Article • Oncogenesis, July 2012, Springer Science + Business Media

    Lisardo Bosca

  110. Propiedades antiinflamatorias de los ácidos grasos poliinsaturados omega-3. Indicaciones en oftalmología

    Article • Archivos de la Sociedad Española de Oftalmología, July 2012, Elsevier

    Lisardo Bosca

  111. Critical role of the death receptor pathway in the antitumoral effects induced by hispanolone derivatives

    Article • Oncogene, February 2012, Springer Science + Business Media

    Lisardo Bosca

  112. Protein Kinase C (PKC)ζ-mediated GαqStimulation of ERK5 Protein Pathway in Cardiomyocytes and Cardiac Fibroblasts

    Article • Journal of Biological Chemistry, January 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  113. Relevance of the MEK/ERK Signaling Pathway in the Metabolism of Activated Macrophages: A Metabolomic Approach

    Article • The Journal of Immunology, December 2011, The American Association of Immunologists

    Lisardo Bosca

  114. Labdane diterpenes protect against anoxia/reperfusion injury in cardiomyocytes: involvement of AKT activation

    Article • Cell Death and Disease, November 2011, Springer Science + Business Media

    Lisardo Bosca

  115. Anti-Inflammatory and Antioxidant Properties of a New Arylidene-Thiazolidinedione in Macrophages

    Article • Current Medicinal Chemistry, August 2011, Bentham Science Publishers

    Lisardo Bosca

  116. Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: Implications for NO synthase 2 expression

    Article • European Journal of Immunology, May 2011, Wiley

    Lisardo Bosca

  117. Transgenic Mice Expressing Cyclooxygenase-2 in Hepatocytes Reveal a Minor Contribution of This Enzyme to Chemical Hepatocarcinogenesis

    Article • American Journal Of Pathology, March 2011, Elsevier

    Lisardo Bosca

  118. Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C

    Article • Journal of Hepatology, January 2011, Elsevier

    Lisardo Bosca

  119. Benznidazole blocks NF-κB activation but not AP-1 through inhibition of IKK

    Article • Molecular Immunology, September 2010, Elsevier

    Lisardo Bosca

  120. Retinoid X receptor α controls innate inflammatory responses through the up-regulation of chemokine expression

    Article • Proceedings of the National Academy of Sciences, May 2010, Proceedings of the National Academy of Sciences

    Lisardo Bosca

  121. Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

    Article • The Journal of Immunology, May 2010, The American Association of Immunologists

    Lisardo Bosca

  122. Cilastatin Attenuates Cisplatin-Induced Proximal Tubular Cell Damage

    Article • Journal of Pharmacology and Experimental Therapeutics, April 2010, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Lisardo Bosca

  123. Electronegative LDL induction of apoptosis in macrophages: Involvement of Nrf2

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, April 2010, Elsevier

    Lisardo Bosca

  124. ILK mediates LPS-induced vascular adhesion receptor expression and subsequent leucocyte trans-endothelial migration†

    Article • Cardiovascular Research, February 2010, European Society of Cardiology

    Lisardo Bosca

  125. Bioactivity of nitrolinoleate: effects on adhesion molecules and CD40–CD40L system☆

    Article • The Journal of Nutritional Biochemistry, February 2010, Elsevier

    Lisardo Bosca

  126. Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways

    Article • Cell Death and Differentiation, January 2010, Springer Science + Business Media

    Lisardo Bosca

  127. Mice Lacking Thyroid Hormone Receptor β Show Enhanced Apoptosis and Delayed Liver Commitment for Proliferation after Partial Hepatectomy

    Article • PLOS One, January 2010, PLOS

    Lisardo Bosca

  128. COX-2 in liver, from regeneration to hepatocarcinogenesis: What we have learned from animal models?

    Article • World Journal of Gastroenterology, January 2010, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Lisardo Bosca

  129. Impairment of Transforming Growth Factor β Signaling in Caveolin-1-deficient Hepatocytes

    Article • Journal of Biological Chemistry, December 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  130. Vasorelaxant and anti-platelet aggregation effects of aqueous Ocimum basilicum extract

    Article • Journal of Ethnopharmacology, August 2009, Elsevier

    Lisardo Bosca

  131. Constitutive COX-2 activity in cardiomyocytes confers permanent cardioprotection

    Article • Journal of Molecular and Cellular Cardiology, February 2009, Elsevier

    Lisardo Bosca

  132. Constitutive expression of cyclo-oxygenase 2 transgene in hepatocytes protects against liver injury

    Article • Biochemical Journal, December 2008, Portland Press Ltd.

    Lisardo Bosca

  133. Implication of Glutamate in the Expression of Inducible Nitric Oxide Synthase After Oxygen and Glucose Deprivation in Rat Forebrain Slices

    Article • Journal of Neurochemistry, July 2008, Wiley

    Prof Maria Angeles Moro, Lisardo Bosca

  134. Supression of inflammatory responses by labdane-type diterpenoids☆

    Article • Toxicology and Applied Pharmacology, April 2008, Elsevier

    Lisardo Bosca

  135. Kaurane diterpenes protect against apoptosis and inhibition of phagocytosis in activated macrophages

    Article • Bone Marrow Transplantation, September 2007, Wiley

    Lisardo Bosca

  136. Selective Impairment of Nuclear Factor-κB-Dependent Gene Transcription in Adult Cardiomyocytes

    Article • American Journal Of Pathology, September 2007, Elsevier

    Lisardo Bosca

  137. Atherogenesis takes place in cholesterol-fed rabbits when circulating concentrations of endogenous cortisol are increased and inflammation suppressed

    Article • Atherosclerosis, April 2007, Elsevier

    Lisardo Bosca

  138. TLR4-Mediated Survival of Macrophages Is MyD88 Dependent and Requires TNF-α Autocrine Signalling

    Article • The Journal of Immunology, March 2007, Oxford University Press (OUP)

    Lisardo Bosca

  139. Selective Activation of Liver X Receptors by Acanthoic Acid-Related Diterpenes

    Article • Molecular Pharmacology, February 2007, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Lisardo Bosca

  140. Animal models for the study of liver regeneration: role of nitric oxide and prostaglandins

    Article • Frontiers in Bioscience, January 2007, Frontiers in Bioscience

    Lisardo Bosca

  141. Dispensability and dynamics of caveolin-1 during liver regeneration and in isolated hepatic cells

    Article • Hepatology, January 2007, Wiley

    Lisardo Bosca

  142. Identification of conserved domains in the promoter regions of nitric oxide synthase 2: implications for the species-specific transcription and evolutionary differences

    Article • BMC Genomics, January 2007, Springer Science + Business Media

    Lisardo Bosca

  143. Protection against Fas-induced liver apoptosis in transgenic mice expressing cyclooxygenase 2 in hepatocytes

    Article • Hepatology, January 2007, Wiley

    Lisardo Bosca

  144. Infiltration of Inflammatory Cells Plays an Important Role in Matrix Metalloproteinase Expression and Activation in the Heart during Sepsis

    Article • American Journal Of Pathology, November 2006, Elsevier

    Lisardo Bosca

  145. Surgical Excision of Bone Sarcomas Involving the Sacroiliac Joint

    Article • Clinical Orthopaedics and Related Research, October 2006, Wolters Kluwer Health

    Lisardo Bosca

  146. Cyclo-oxygenase 2 expression impairs serum-withdrawal-induced apoptosis in liver cells

    Article • Biochemical Journal, September 2006, Portland Press Ltd.

    Lisardo Bosca

  147. Specific Contribution of p19ARF to Nitric Oxide-Dependent Apoptosis

    Article • The Journal of Immunology, August 2006, The American Association of Immunologists

    Lisardo Bosca

  148. The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells

    Article • Biochemical and Biophysical Research Communications, August 2006, Elsevier

    Lisardo Bosca

  149. Involvement of mitogen-activated protein kinases in the symbiosis Bradyrhizobium-Lupinus

    Article • Journal of Experimental Botany, July 2006, Oxford University Press (OUP)

    Lisardo Bosca

  150. Cyclooxygenase 2: understanding the pathophysiological role through genetically altered mouse models

    Article • Frontiers in Bioscience, January 2006, Frontiers in Bioscience

    Lisardo Bosca

  151. The Nonthiazolidinedione PPARγ Agonist L-796,449 Is Neuroprotective in Experimental Stroke

    Article • Journal of Neuropathology & Experimental Neurology, September 2005, Oxford University Press (OUP)

    Lisardo Bosca

  152. Potentiation of tumor formation by topical administration of 15-deoxy-Δ 12,14 -prostaglandin J 2 in a model of skin carcinogenesis

    Article • Carcinogenesis, August 2005, Oxford University Press (OUP)

    Lisardo Bosca

  153. Rosiglitazone and 15-deoxy-Δ12,14-prostaglandin J2 Cause Potent Neuroprotection after Experimental Stroke through Noncompletely Overlapping Mechanisms

    Article • Journal of Cerebral Blood Flow & Metabolism, July 2005, SAGE Publications

    Prof Maria Angeles Moro, Lisardo Bosca

  154. Assessment of a dual regulatory role for NO in liver regeneration after partial hepatectomy: protection against apoptosis and retardation of hepatocyte proliferation

    Article • The FASEB Journal, April 2005, Federation of American Societies For Experimental Biology (FASEB)

    Lisardo Bosca

  155. Prostaglandin E 2 promotes migration and adhesion in hepatocellular carcinoma cells

    Article • Carcinogenesis, April 2005, Oxford University Press (OUP)

    Lisardo Bosca

  156. Nitric oxide and cell viability in inflammatory cells: a role for NO in macrophage function and fate

    Article • Toxicology, March 2005, Elsevier

    Lisardo Bosca

  157. Nitric Oxide and Cell Signaling: In Vivo Evaluation of NO‐Dependent Apoptosis by MRI and Not NMR Techniques

    Article • January 2005, Elsevier

    Lisardo Bosca

  158. PGE1-induced NO reduces apoptosis by D-galactosamine through attenuation of NF-κB and NOS-2 expression in rat hepatocytes

    Article • Hepatology, December 2004, Wiley

    Lisardo Bosca

  159. A New Family of Synthetic Diterpenes that Regulates Cytokine Synthesis by Inhibiting IκBα Phosphorylation

    Article • ChemBioChem, November 2004, Wiley

    Lisardo Bosca

  160. Attenuation of NF-?B signalling in rat cardiomyocytes at birth restricts the induction of inflammatory genes

    Article • Cardiovascular Research, November 2004, European Society of Cardiology

    Lisardo Bosca

  161. Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins

    Article • Gut, November 2004, BMJ

    Lisardo Bosca

  162. The P34G Mutation Reduces the Transforming Activity of K-Ras and N-Ras in NIH 3T3 Cells but Not of H-Ras

    Article • Journal of Biological Chemistry, June 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  163. Simultaneous abrogation of NOS-2 and COX-2 activities is lethal in partially hepatectomised mice

    Article • Journal of Hepatology, June 2004, Elsevier

    Lisardo Bosca

  164. Thioacetamide-induced liver regeneration involves the expression of cyclooxygenase 2 and nitric oxide synthase 2 in hepatocytes

    Article • Journal of Hepatology, June 2004, Elsevier

    Lisardo Bosca

  165. Induction of nitric oxide synthase-2 proceeds with the concomitant downregulation of the endogenous caveolin levels

    Article • Journal of Cell Science, May 2004, The Company of Biologists

    Professor Francisco Gavilanes, Lisardo Bosca

  166. Regional distribution of hyperpolarization-activated current (If) and hyperpolarization-activated cyclic nucleotide-gated channel mRNA expression in ventricular cells from control and hypertrophied rat hearts

    Article • The Journal of Physiology, December 2003, Wiley

    Lisardo Bosca

  167. Sustained Nitric Oxide Delivery Delays Nitric Oxide-Dependent Apoptosis in Macrophages: Contribution to the Physiological Function of Activated Macrophages

    Article • The Journal of Immunology, November 2003, The American Association of Immunologists

    Lisardo Bosca

  168. Thromboxane A 2 -Induced Inhibition of Voltage-Gated K + Channels and Pulmonary Vasoconstriction

    Article • Circulation Research, October 2003, Wolters Kluwer Health

    Lisardo Bosca

  169. Induction of Cyclooxygenase-2 Accounts for Restraint Stress-Induced Oxidative Status in Rat Brain

    Article • Neuropsychopharmacology, April 2003, Springer Science + Business Media

    Prof Maria Angeles Moro, Lisardo Bosca

  170. The cyclopentenone 15-deoxy-Δ 12,14 -prostaglandin J 2 binds to and activates H-Ras

    Article • Proceedings of the National Academy of Sciences, April 2003, Proceedings of the National Academy of Sciences

    Lisardo Bosca

  171. The nNOS inhibitor, AR-R17477AR, prevents the loss of NF68 immunoreactivity induced by methamphetamine in the mouse striatum

    Article • Journal of Neurochemistry, April 2003, Wiley

    Lisardo Bosca

  172. Ammonia prevents glutamate-induced but not low K+-induced apoptosis in cerebellar neurons in culture

    Article • Neuroscience, April 2003, Elsevier

    Lisardo Bosca

  173. PKCε is a permissive link in integrin-dependent IFN-γ signalling that facilitates JAK phosphorylation of STAT1

    Article • Nature Cell Biology, March 2003, Springer Science + Business Media

    Lisardo Bosca

  174. Selective Inhibitors of Cyclooxygenase-2 Delay the Activation of Nuclear Factor κB and Attenuate the Expression of Inflammatory Genes in Murine Macrophages Treated with Lipopolysaccharide

    Article • Molecular Pharmacology, March 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Lisardo Bosca

  175. Potentiation of Protein Kinase C ζ Activity by 15-Deoxy-Δ12,14-Prostaglandin J2 Induces an Imbalance between Mitogen-Activated Protein Kinases and NF-κB That Promotes Apoptosis in Macrophages

    Article • Molecular and Cellular Biology, February 2003, ASM Journals

    Lisardo Bosca

  176. Presence of methylated arginine derivatives in orthotopic human liver transplantation: Relevance for liver function

    Article • Liver Transplantation, January 2003, Wiley

    Lisardo Bosca

  177. H-Ras-specific activation of NF-κB protects NIH 3T3 cells against stimulus-dependent apoptosis

    Article • Oncogene, October 2002, Springer Science + Business Media

    Lisardo Bosca

  178. Interleukin-4 and interleukin-10 modulate nuclear factor κB activity and nitric oxide synthase-2 expression in Theiler's virus-infected brain astrocytes

    Article • Journal of Neurochemistry, June 2002, Wiley

    Lisardo Bosca

  179. Induction of apoptosis by nitric oxide in macrophages is independent of apoptotic volume decreas

    Article • Cell Death and Differentiation, May 2002, Springer Science + Business Media

    Lisardo Bosca

  180. Coexistence of translocated cytochrome c and nitrated protein in neurons of the rat cerebral cortex after oxygen and glucose deprivation

    Article • Neuroscience, April 2002, Elsevier

    Lisardo Bosca

  181. The Increase in TNF-α Levels Is Implicated in NF-κB Activation and Inducible Nitric Oxide Synthase Expression in Brain Cortex after Immobilization Stress

    Article • Neuropsychopharmacology, February 2002, Springer Science + Business Media

    Prof Maria Angeles Moro, Lisardo Bosca

  182. Absence of nuclear factor κB inhibition by NSAIDs in hepatocytes

    Article • Hepatology, February 2002, Wiley

    Lisardo Bosca

  183. Article • Metabolic Brain Disease, January 2002, Springer Science + Business Media

    Lisardo Bosca

  184. Nitric oxide and resolution of inflammation

    Article • January 2002, Elsevier

    Lisardo Bosca

  185. Chronic Stress Induces the Expression of Inducible Nitric Oxide Synthase in Rat Brain Cortex

    Article • Journal of Neurochemistry, December 2001, Wiley

    Prof Maria Angeles Moro, Lisardo Bosca

  186. Protein Kinase Cϵ Is Required for Macrophage Activation and Defense Against Bacterial Infection

    Article • Journal of Experimental Medicine, October 2001, Rockefeller University Press

    Lisardo Bosca

  187. Intracellular water motion decreases in apoptotic macrophages after caspase activation

    Article • Cell Death and Differentiation, October 2001, Springer Science + Business Media

    Lisardo Bosca

  188. Contribution of cyclooxygenase-2 to liver regeneration after partial hepatectomy

    Article • The FASEB Journal, July 2001, Federation of American Societies For Experimental Biology (FASEB)

    Lisardo Bosca

  189. Peroxisome Proliferator-activated Receptor-γ-independent Inhibition of Macrophage Activation by the Non-thiazolidinedione Agonist L-796,449

    Article • Journal of Biological Chemistry, July 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  190. Up-regulation of TNF-α convertase (TACE/ADAM17) after oxygen–glucose deprivation in rat forebrain slices

    Article • Neuropharmacology, June 2001, Elsevier

    Prof Maria Angeles Moro, Lisardo Bosca

  191. Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes

    Article • Hepatology, April 2001, Wiley

    Lisardo Bosca

  192. Inhibition of the Nuclear Factor  B (NF- B) Pathway by Tetracyclic Kaurene Diterpenes in Macrophages: SPECIFIC EFFECTS ON NF- B-INDUCING KINASE ACTIVITY AND ON THE COORDINATE ACTIVATION OF ERK AND p38 MAPK

    Article • Journal of Biological Chemistry, February 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  193. Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor κB-mediated mechanisms

    Article • Journal of Neurochemistry, January 2001, Wiley

    Prof Maria Angeles Moro, Lisardo Bosca

  194. Contribution of Cyclopentenone Prostaglandins to the Resolution of Inflammation Through the Potentiation of Apoptosis in Activated Macrophages

    Article • The Journal of Immunology, December 2000, The American Association of Immunologists

    Lisardo Bosca

  195. Regulation of cyclooxygenase 2 expression in hepatocytes by CCAAT/enhancer-binding proteins

    Article • Gastroenterology, August 2000, Elsevier

    Lisardo Bosca

  196. Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices

    Article • Neuropharmacology, June 2000, Elsevier

    Prof Maria Angeles Moro, Lisardo Bosca

  197. Localisations métastatiques atypiques d’un cancer du rectum

    Article • Annales de Chirurgie, June 2000, Elsevier

    Lisardo Bosca

  198. Anti-inflammatory action of type I interferons deduced from mice expressing interferon β

    Article • Gene Therapy, May 2000, Springer Science + Business Media

    Lisardo Bosca

  199. Inhibition of IκB Kinase and IκB Phosphorylation by 15-Deoxy-Δ12,14-Prostaglandin J2 in Activated Murine Macrophages

    Article • Molecular and Cellular Biology, March 2000, ASM Journals

    Lisardo Bosca

  200. Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: involvement of phosphatidylinositol 3-kinase

    Article • Diabetes, February 2000, American Diabetes Association

    Lisardo Bosca

  201. Inhibition of NOS-2 expression in macrophages through the inactivation of NF-κ B by andalusol

    Article • Bone Marrow Transplantation, October 1999, Wiley

    Lisardo Bosca

  202. Mechanisms of Nitric Oxide-Dependent Apoptosis: Involvement of Mitochondrial Mediators

    Article • Cellular Signalling, April 1999, Elsevier

    Lisardo Bosca

  203. Presence of a nitric oxide synthase inhibitor in the graft efflux during reperfusion in human liver transplantation

    Article • Clinical Transplantation, March 1999, Wiley

    Lisardo Bosca

  204. Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages

    Article • Bone Marrow Transplantation, March 1999, Wiley

    Lisardo Bosca

  205. Down-Regulation of Neuronal Nitric Oxide Synthase by Nitric Oxide After Oxygen-Glucose Deprivation in Rat Forebrain Slices

    Article • Journal of Neurochemistry, January 1999, Wiley

    Lisardo Bosca

  206. Expression of cyclooxygenase-2 in foetal rat hepatocytes stimulated with lipopolysaccharide and pro-inflammatory cytokines

    Article • Bone Marrow Transplantation, November 1998, Wiley

    Lisardo Bosca

  207. Interferon-α/β Inhibits the Apoptosis Induced by Lipopolysaccharide and Interferon-γ in Murine Peritoneal Macrophages

    Article • Journal of Interferon & Cytokine Research, July 1998, Mary Ann Liebert Inc

    Lisardo Bosca

  208. Suppression of HIV-1 infection in linomide-treated SCID-hu-PBL mice

    Article • AIDS, May 1998, Wolters Kluwer Health

    Lisardo Bosca

  209. Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices

    Article • European Journal of Neuroscience, February 1998, Wiley

    Prof Maria Angeles Moro, Lisardo Bosca

  210. Differential regulation of nitric oxide synthase mRNA expression by lipopolysaccharide and pro-inflammatory cytokines in fetal hepatocytes treated with cycloheximide

    Article • Biochemical Journal, November 1997, Portland Press Ltd.

    Lisardo Bosca

  211. Nuclear factorκB is required for the transcriptional control of type II NO synthase in regenerating liver

    Article • Biochemical Journal, September 1997, Portland Press Ltd.

    Lisardo Bosca

  212. Rapid Up-regulation of IκBβ and Abrogation of NF-κB Activity in Peritoneal Macrophages Stimulated with Lipopolysaccharide

    Article • Journal of Biological Chemistry, September 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  213. Requirement of nitric oxide and calcium mobilization for the induction of apoptosis in adrenal vascular endothelial cells

    Article • FEBS Letters, August 1997, Wiley

    Lisardo Bosca

  214. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition

    Article • FEBS Letters, June 1997, Wiley

    Lisardo Bosca

  215. Absence of NO synthase type II expression in fetal liver from pregnant rats under septic shock conditions

    Article • Hepatology, June 1997, Wiley

    Lisardo Bosca

  216. Involvement of nitric oxide synthesis in hepatic perturbations induced in rats by a necrogenic dose of thioacetamide

    Article • Bone Marrow Transplantation, June 1997, Wiley

    Lisardo Bosca

  217. Expression of the calcium-independent cytokine-inducible (iNOS) isoform of nitric oxide synthase in rat placenta

    Article • Biochemical Journal, May 1997, Portland Press Ltd.

    Lisardo Bosca

  218. Regulation of rat liver S-adenosylmethionine synthetase during septic shock: Role of nitric oxide

    Article • Hepatology, February 1997, Wiley

    Lisardo Bosca

  219. Up-Regulation of Protein Kinase C-ϵ Promotes the Expression of Cytokine-inducible Nitric Oxide Synthase in RAW 264.7 Cells

    Article • Journal of Biological Chemistry, December 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  220. Evidence for Common Mechanisms in the Transcriptional Control of Type II Nitric Oxide Synthase in Isolated Hepatocytes

    Article • Journal of Biological Chemistry, November 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  221. Differential expression pattern of S-adenosylmethionine synthetase isoenzymes during rat liver development

    Article • Hepatology, October 1996, Wiley

    Dr María Ángeles Pajares, Lisardo Bosca

  222. Bacterial lipopolysaccharide antagonizes transforming growth factor ?1-induced apoptosis in primary cultures of hepatocytes

    Article • Hepatology, May 1996, Wiley

    Lisardo Bosca

  223. CD53 Antigen and Epidermal Growth Factor Induce Similar Changes in the Pattern of Phorbol Ester Binding in a B Cell Lymphoma

    Article • Cellular Immunology, April 1996, Elsevier

    Lisardo Bosca

  224. Multiple forms of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase are expressed in perinatal rat liver

    Article • AJP Endocrinology and Metabolism, February 1996, American Physiological Society

    Lisardo Bosca

  225. Characterization of nitric oxide dependent changes in carbohydrate hepatic metabolism during septic shock

    Article • Life Sciences, January 1996, Elsevier

    Lisardo Bosca

  226. Differential regulation of the expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and pyruvate kinase by cyclic adenosine 3′,5′-monophosphate in fetal and adult hepatocytes

    Article • Journal of Cellular Physiology, December 1995, Wiley

    Lisardo Bosca

  227. Epidermal growth factor inhibits cytokine-dependent nitric oxide synthase expression in hepatocytes

    Article • FEBS Letters, July 1995, Wiley

    Lisardo Bosca

  228. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels.

    Article • Journal of Clinical Investigation, April 1995, American Society for Clinical Investigation

    Lisardo Bosca

  229. Bacterial Lipopeptides Induce Nitric Oxide Synthase and Promote Apoptosis through Nitric Oxide-independent Pathways in Rat Macrophages

    Article • Journal of Biological Chemistry, March 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Lisardo Bosca

  230. Nitric oxide is released in regenerating liver after partial hepatectomy*1

    Article • Hepatology, March 1995, Elsevier

    Lisardo Bosca

  231. Platelet-activating factor: the effector of protein-rich plasma extravasation and nitric oxide synthase induction in rat immune complex peritonitis

    Article • Bone Marrow Transplantation, February 1995, Wiley

    Lisardo Bosca, Mariano Sanchez Crespo

  232. Protein kinase C (PKC)-induced PKC degradation: a model for down-regulation

    Article • Biochemical Society Transactions, February 1995, Portland Press Ltd.

    Lisardo Bosca

  233. Characterization of Signals Leading to Clonal Expansion or to Cell Death During Lymphocyte B Cell Activation

    Article • January 1995, Springer Science + Business Media

    Lisardo Bosca

  234. From Apoptosis to Autoimmunity: Insights from the Signaling Pathways Leading to Proliferation or to Programmed Cell Death

    Article • Immunological Reviews, December 1994, Wiley

    Lisardo Bosca

  235. Nitric Oxide Implication in the Control of Neurosecretion by Chromaffin Cells

    Article • Journal of Neurochemistry, November 1994, Wiley

    Lisardo Bosca

  236. CD2-CD48 interaction prevents apoptosis in murine B lymphocytes by up-regulating bcl-2 expression

    Article • European Journal of Immunology, October 1994, Wiley

    Lisardo Bosca

  237. Cocaine-induced liver injury in mice elicits specific changes in DNA ploidy and induces programmed death of hepatocytes

    Article • Hepatology, October 1994, Wiley

    Lisardo Bosca

  238. Protein kinase C V3 domain mutants with differential sensitivities to m-calpain are not resistant to phorbol-ester-induced down-regulation

    Article • European Journal of Biochemistry, July 1994, Wiley

    Lisardo Bosca

  239. Induction of nitric oxide release by MRC OX-44 (anti-CD53) through a protein kinase C-dependent pathway in rat macrophages

    Article • Journal of Experimental Medicine, April 1994, Rockefeller University Press

    Lisardo Bosca

  240. Relationship between genomic DNA ploidy and parameters of liver damage during necrosis and regeneration induced by thioacetamide

    Article • Hepatology, October 1993, Wiley

    Lisardo Bosca

  241. Rat liver messenger ribonucleic acid and enzyme activity of 6- phosphofructo 2-kinase/fructose 2,6-bisphosphatase impairment during the late period of pregnancy

    Article • Endocrinology, September 1993, Endocrine Society

    Lisardo Bosca

  242. Rat liver messenger ribonucleic acid and enzyme activity of 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase impairment during the late period of pregnancy.

    Article • Endocrinology, September 1993, Endocrine Society

    Lisardo Bosca

  243. Sulfonylureas activate glycogen phosphorylase and increase cytosolic free-Ca2+ levels in isolated rat hepatocytes

    Article • Metabolism, May 1993, Elsevier

    Lisardo Bosca

  244. Phorbol esters induce nitric oxide synthase and increase arginine influx in cultured peritoneal macrophages

    Article • FEBS Letters, April 1993, Wiley

    Lisardo Bosca

  245. Signal Transduction Pathways Involved in B-Cell Induction

    Article • Immunological Reviews, April 1993, Wiley

    Lisardo Bosca

  246. Circular dichroism analysis of ligand-induced conformational changes in protein kinase C. Mechanism of translocation of the enzyme from the cytosol to the membranes and its implications

    Article • Biochemical Journal, March 1993, Portland Press Ltd.

    Lisardo Bosca

  247. Differential calcium mobilization by vasopressin, angiotensin II, gastrin-releasing peptide, and adenosine triphosphate in adult and fetal hepatocytes. Relevance for the activation of calcium-dependent enzymes

    Article • Endocrinology, January 1993, Endocrine Society

    Lisardo Bosca

  248. Differential calcium mobilization by vasopressin, angiotensin II, gastrin-releasing peptide, and adenosine triphosphate in adult and fetal hepatocytes. Relevance for the activation of calcium-dependent enzymes.

    Article • Endocrinology, January 1993, Endocrine Society

    Lisardo Bosca

  249. Isoenzymes of carbohydrate metabolism in primary cultures of hepatocytes from thioacetamide-induced rat liver necrosis: Responses to growth factors

    Article • Hepatology, July 1992, Wiley

    Lisardo Bosca

  250. Phorbol esters, bombesin and insulin elicit differential responses on the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase system in primary cultures of foetal and adult rat hepatocytes

    Article • European Journal of Biochemistry, July 1992, Wiley

    Lisardo Bosca

  251. Inhibition of 6-phosphofructo-2-kinase activity by mercaptopurines

    Article • Biochemical Pharmacology, February 1992, Elsevier

    Lisardo Bosca

  252. Characterization of 6-phosphofructo-2-kinase from foetal-rat liver

    Article • Biochemical Journal, January 1992, Portland Press Ltd.

    Lisardo Bosca

  253. Inactivation of 6-phosphofructo-2-kinase during anaerobiosis in the marine whelk Busycon canaliculatum

    Article • AJP Regulatory Integrative and Comparative Physiology, June 1991, American Physiological Society

    Lisardo Bosca

  254. Substrate specificity of protein kinase C inhibitors

    Article • Trends in Pharmacological Sciences, November 1990, Elsevier

    Lisardo Bosca

  255. Lack of translocation of protein kinase C from the cytosol to the membranes in vasopressin-stimulated hepatocytes

    Article • Biochemical Journal, July 1990, Portland Press Ltd.

    Lisardo Bosca

  256. Substrate-dependent inhibition of protein kinase C by specific inhibitors

    Article • FEBS Letters, April 1990, Wiley

    Lisardo Bosca

  257. Identification of an anti-A and anti-B blood group glycosyltransferase antibody after incompatible bone marrow transplant

    Article • Blood, August 1989, American Society of Hematology

    Lisardo Bosca

  258. Lack of correlation betwen translocation and biological effects mediated by protein kinase C: an appraisal

    Article • Immunology Today, July 1989, Elsevier

    Lisardo Bosca

  259. Oleate-induced translocation of protein kinase C to hepatic microsomal membranes

    Article • Biochemical and Biophysical Research Communications, May 1989, Elsevier

    Lisardo Bosca

  260. Translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in thioacetamide-induced liver tumours in rats

    Article • Toxicology Letters, April 1989, Elsevier

    Lisardo Bosca

  261. Glucagon-induced changes in fructose 2,6-bisphosphate and 6-phosphofructo-2-kinase in cultured rat foetal hepatocytes

    Article • Biochemical Journal, February 1989, Portland Press Ltd.

    Lisardo Bosca

  262. Presence of antibody to A- and B-transferases in minor incompatible bone marrow transplants

    Article • British Journal of Haematology, December 1988, Wiley

    Lisardo Bosca

  263. Age-related changes in the translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in rat liver

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, November 1988, Elsevier

    Lisardo Bosca

  264. Phorbol 12,13-dibutyrate and mitogens increase fructose 2,6-bisphosphate in lymphocytes. Comparison of lymphocyte and rat-liver 6-phosphofructo-2-kinase

    Article • European Journal of Biochemistry, August 1988, Wiley

    Lisardo Bosca

  265. Phorbol ester translocation of protein kinase C in guinea-pig synaptosomes and the potentiation of calcium-dependent glutamate release

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 1988, Elsevier

    Lisardo Bosca

  266. Activation of protein kinase C from B lymphocytes by lipid A

    Article • Biochemical and Biophysical Research Communications, April 1988, Elsevier

    Lisardo Bosca

  267. Fructose 2,6-bisphosphate in isolated foetal hepatocytes

    Article • FEBS Letters, December 1987, Wiley

    Lisardo Bosca

  268. Expression of the v-src or v-fps oncogene increases fructose 2,6-bisphosphate in chick-embryo fibroblasts. Novel mechanism for the stimulation of glycolysis by retroviruses

    Article • Biochemical Journal, June 1986, Portland Press Ltd.

    Lisardo Bosca

  269. Effect of glutamine on fructose 2,6-bisphosphate and on glucose metabolism in HeLa cells and in chick-embryo fibroblasts

    Article • Biochemical Journal, December 1985, Portland Press Ltd.

    Lisardo Bosca

  270. Phorbol 12-myristate 13-acetate and insulin increase the concentration of fructose 2,6-bisphosphate and stimulate glycolysis in chicken embryo fibroblasts.

    Article • Proceedings of the National Academy of Sciences, October 1985, Proceedings of the National Academy of Sciences

    Lisardo Bosca

  271. The effect of fructose 2,6-bisphosphate on muscle fructose-1,6-bisphosphatase activity

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, April 1985, Elsevier

    Lisardo Bosca

  272. A problematic enzyme

    Article • Trends in Biochemical Sciences, February 1985, Elsevier

    Lisardo Bosca

  273. Difference in glucose sensitivity of liver glycolysis and glycogen synthesis. Relationship between lactate production and fructose 2,6-bisphosphate concentration

    Article • Biochemical Journal, December 1984, Portland Press Ltd.

    Lisardo Bosca

  274. Is phosphofructokinase the rate-limiting step of glycolysis?

    Article • Trends in Biochemical Sciences, September 1984, Elsevier

    Lisardo Bosca

  275. Biphasic effect of fructose 2,6-bisphosphate on the liver fructose-1,6-bisphosphatase: mechanistic and physiological implications

    Article • FEBS Letters, February 1984, Wiley

    Lisardo Bosca

  276. Specific activation by fructose 2,6-bisphosphate and inhibition by P-enolpyruvate of ascites tumor phosphofructokinase

    Article • Biochemical and Biophysical Research Communications, May 1982, Elsevier

    Lisardo Bosca

  277. Mitochondrial Membrane-Bound Hexokinase of Ascites Tumor Cells. Functional Implications of Lysine Residues Studied by Modification with Imidoesters

    Article • Hoppe-Seyler´s Zeitschrift für physiologische Chemie, January 1982, De Gruyter

    Lisardo Bosca

  278. Measurement of NOS mRNA by Northern Blotting and the Ribonuclease-Protection Assay

    Article • Springer Science + Business Media

    Lisardo Bosca