All Stories

  1. Concordance of Direct and Indirect Measures of Medication Adherence in A Treatment Trial for Cannabis Dependence
  2. Practice What We Publish
  3. An Epidemic of Opioid Prescriptions
  4. Parents and Mentors May Be Gone but They Are Never Forgotten
  5. Basic Science and the Ebola Virus Infection Epidemic
  6. Behind the Cover atPharmacotherapy
  7. Pig Fat, Pork Bellies, and Portly Appearance
  8. Marijuana Use in America: Whither Are We Bound?
  9. What Evidence is Required for Drug Exposure to be Causally Associated with Adverse Events? The Case for Case Reports Published inPharmacotherapy
  10. Celebrating 32 Years of Pharmacotherapy
  11. Human Psychopharmacology: the first twenty-five years
  12. Exposing Fetal Drug Exposure
  13. Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic
  14. P-glycoprotein inhibition potentiates the behavioural and neurochemical actions of risperidone in rats
  15. P.1.b.007 Developmental expression and activity of carboxylesterase 1 and carboxylesterase 2 in mouse and human
  16. Aripiprazole brain concentration is altered in P-glycoprotein deficient mice
  17. Principles of Pharmacokinetics and Pharmacodynamics
  18. Pro-inflammatory biomakers in depression: Treatment with venlafaxine
  19. Antipsychotic Drugs Inhibit the Function of Breast Cancer Resistance Protein
  20. Two CES1 Gene Mutations Lead to Dysfunctional Carboxylesterase 1 Activity in Man: Clinical Significance and Molecular Basis
  21. Enantiospecific gas chromatographic–mass spectrometric analysis of urinary methylphenidate: Implications for phenotyping
  22. Pro-inflammatory biomakers in depression: Treatment with venlafaxine
  23. Sertraline and Its Metabolite Desmethylsertraline, but not Bupropion or Its Three Major Metabolites, Have High Affinity for P-Glycoprotein
  24. Interactions of attention-deficit/hyperactivity disorder therapeutic agents with the efflux transporter P-glycoprotein
  25. A novel HPLC fluorescence method for the quantification of methylphenidate in human plasma
  26. Atypical Antipsychotic Administration During Late Pregnancy: Placental Passage and Obstetrical Outcomes
  27. Double-blind donepezil–placebo crossover augmentation study of atypical antipsychotics in chronic, stable schizophrenia: A pilot study
  28. Sensitive quantification of atomoxetine in human plasma by HPLC with fluorescence detection using 4-(4,5-diphenyl-1H-imidazole-2-yl) benzoyl chloride derivatization
  29. Open-label steady-state pharmacokinetic drug interaction study on co-administered quetiapine fumarate and divalproex sodium in patients with schizophrenia, schizoaffective disorder, or bipolar disorder
  30. The Emerging Importance of Transporter Proteins in the Psychopharmacological Treatment of the Pregnant Patient
  31. A Comprehensive In Vitro Screening of d-, l- , and dl-threo -Methylphenidate: An Exploratory Study
  32. Risperidone and Paliperidone Inhibit P-Glycoprotein Activity In Vitro
  33. Counterpoint
  34. Antidepressant–Drug Interactions are Potentially but Rarely Clinically Significant
  35. Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein
  36. Placental Passage of Tricyclic Antidepressants
  37. Pharmacokinetics of Olanzapine After Single-Dose Oral Administration of Standard Tablet Versus Normal and Sublingual Administration of an Orally Disintegrating Tablet in Normal Volunteers
  38. PIII-63The cannabinoid cannabidiol inhibits P-glycoprotein activity
  39. Modafinil and Cocaine Interactions
  40. Antidepressants in Amniotic Fluid: Another Route of Fetal Exposure
  41. Population pharmacokinetic analysis of drug–drug interactions among risperidone, bupropion, and sertraline in CF1 mice
  42. Donepezil effects on mood in patients with schizophrenia and schizoaffective disorder
  43. Effect ofGinkgo bilobaExtract on Plasma Steroid Concentrations in Healthy Volunteers: A Pilot Study
  44. P-glycoprotein does not actively transport nicotine and cotinine
  45. Modafinil Influences the Pharmacokinetics of Intravenous Cocaine in Healthy Cocaine-Dependent Volunteers
  46. Effects of St John's wort (Hypericum perforatum L.) extract on plasma androgen concentrations in healthy men and women: a pilot study
  47. The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein
  48. Effect of St. John’s Wort on Drug Metabolism by Induction of Cytochrome P450 3A4 Enzyme
  49. Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood?brain barrier of Abcb1a gene knockout mice
  50. Comparative CYP3A4 Inhibitory Effects of Venlafaxine, Fluoxetine, Sertraline, and Nefazodone in Healthy Volunteers
  51. Multiple-Dose Administration of Ginkgo biloba Did Not Affect Cytochrome P-450 2D6 or 3A4 Activity in Normal Volunteers
  52. Dietary levels of quinine in tonic water do not inhibit CYP2D6 in vivo
  53. Augmenting Atypical Antipsychotics with a Cognitive Enhancer (Donepezil) Improves Regional Brain Activity in Schizophrenia Patients: A Pilot Double-blind Placebo Controlled BOLD fMRI Study
  54. Chiral Analysis of d- and l-Modafinil in Human Serum: Application to Human Pharmacokinetic Studies
  55. Pharmacokinetics of Methylphenidate After Oral Administration of Two Modified-Release Formulations in Healthy Adults
  56. Differential Time Course of Cytochrome P450 2D6 Enzyme Inhibition by Fluoxetine, Sertraline, and Paroxetine in Healthy Volunteers
  57. Clinical Pharmacokinetics of Sertraline
  58. Hypotension and Bradycardia in a Healthy Volunteer following a Single 5 mg Dose of Olanzapine
  59. Clinical Applications of Modafinil in Stimulant Abusers: Low Abuse Potential
  60. Intranasal Sumatriptan in Post-ECT Headache: Results of an Open-Label Trial
  61. Drug Glucuronidation in Clinical Psychopharmacology
  62. Substance P: A New Era, a New Role
  63. An Evaluation of Risperidone Drug Interactions
  64. Lack of Citalopram Effect on the Pharmacokinetics of Cyclosporine
  65. A single dose of methadone inhibits cytochrome P-4503A activity in healthy volunteers as assessed by the urinary cortisol ratio
  66. Clinical Pharmacokinetics of Quetiapine
  67. A Double-blind Placebo-controlled Case Study of the Use of Donepezil to Improve Cognition in a Schizoaffective Disorder Patient: Functional MRI Correlates.
  68. A Double-blind Placebo-controlled Case Study of the Use of Donepezil to Improve Cognition in a Schizoaffective Disorder Patient: Functional MRI Correlates.
  69. Nefazodone in Diabetic Neuropathy: Response and Biology
  70. Drs. DeVane and Pollock Reply
  71. Single-Dose Pharmacokinetics of Methylphenidate in CYP2D6 Extensive and Poor Metabolizers
  72. Sertraline in Diabetic Neuropathy: Response and Biology
  73. Olanzapine Pharmacokinetics in Pediatric and Adolescent Inpatients With Childhood-Onset Schizophrenia
  74. Rifampin-Induced Selective Serotonin Reuptake Inhibitor Withdrawal Syndrome in a Patient Treated With Sertraline
  75. Development and application of a chiral high performance liquid chromatography assay for pharmacokinetic studies of methadone
  76. Development and application of a chiral high performance liquid chromatography assay for pharmacokinetic studies of methadone
  77. Fluoxetine-Related Death in a Child with Cytochrome P-450 2D6 Genetic Deficiency
  78. Evaluation of the efficacy, safety and physiological effects of fluvoxamine in social phobia
  79. Effect of St. John's wort on cytochrome (CYP) P-450 activity in healthy volunteers
  80. Mirtazapine in Major Depression With Comorbid Generalized Anxiety Disorder
  81. Suspected Ciprofloxacin Inhibition of Olanzapine Resulting in Increased Plasma Concentration
  82. Pharmacokinetics of trazodone and its major metabolite m-chlorophenylpiperazine in plasma and brain of rats
  83. Drug interactions with psychostimulants
  84. Pharmacokinetics and drug interactions of the newer antidepressants
  85. No Mourning for the Conventional Antipsychotics: The Dawn of the Atypical Agents
  86. Bupropion slow-release response in depression: diagnosis and biochemistry
  87. Therapeutic Drug Monitoring of Alprazolam in Adolescents With Asthma
  88. Lack of urinary side-effects with nefazodone as compared to other newer antidepressants
  89. Lack of urinary side‐effects with nefazodone as compared to other newer antidepressants
  90. 331. Mirtazapine in combined major depression and generalized anxiety disorder
  91. Lack of Antidepressant-Cyclosporine Pharmacokinetic Interactions
  92. Translational pharmacokinetics: Current issues with newer antidepressants
  93. Translational pharmacokinetics: Current issues with newer antidepressants
  94. Extrapyramidal Symptoms Associated With Cyclic Antidepressant Treatment
  95. Psychopharmacology and drug interactions in HIV positive patients
  96. Clozapine Drug-Drug Interactions: A Review of the Literature
  97. Dr. Nemeroff and Colleagues Reply
  98. The Practical Use of Carbon Dioxide-Induced Anxiety in the Diagnosis and Care of Patients with Panic Disorder
  99. Alopecia and Mood Stabilizer Therapy
  100. The evaluation of fluvoxamine in the treatment of social phobia
  101. Theoretical considerations of dose/concentration/effect relationships: Direct and indirect pharmacokinetic/dynamic models
  102. Pharmacokinetics of Clozapine and Risperidone
  103. The reply
  104. Comparative safety and tolerability of selective serotonin reuptake inhibitors
  105. Pharmacokinetics of Single- and Multiple-Dose Bupropion in Elderly Patients with Depression
  106. Pharmacokinetic and Pharmacodynamic Considerations for the Design and Screening of Potential Medications
  107. Pharmacokinetics of the newer antidepressants: Clinical relevance
  108. Evaluation of population pharmacokinetics in therapeutic trials. IV. Application to postmarketing surveillance
  109. Treatment of Aggressive Children with Clonidine: Results of an Open Pilot Study
  110. The Assessment and Clinical Implications of Haloperidol Acute-Dose, Steady-State, and Withdrawal Pharmacokinetics
  111. Fundamentals of Monitoring Psychoactive Drug Therapy—by C. Lindsay DeVane, Pharm.D.; Baltimore, Williams & Wilkins, 1990, 288 pages, $31
  112. STEADY-STATE PREDICTIONS BASED ON FIRST DOSE DATA
  113. Pharmacokinetic and dynamic correlates of intravenous alprazolam challenge
  114. Influence of menstrual cycle and gender on alprazolam pharmacokinetics
  115. Effect of electroconvulsive therapy on serum concentration of alpha-1-acid glycoprotein
  116. Sustained Plasma Concentrations of Fluoxetine and/or Norfluoxetine Four and Eight Weeks After Fluoxetine Discontinuation
  117. Distribution of Phenobarbital and Phenytoin in Pregnant Rats and Their Fetuses
  118. Pharmacokinetic Correlates of Fetal Drug Exposure
  119. Immunologic Effects of Cocaine and Related Alkaloids
  120. Inhalational administration of cocaine in sheep
  121. Disposition of Bupropion in Healthy Volunteers and
  122. Electroconvulsive Therapy Complicated by Insecticide Ingestion
  123. Tissue distribution of cocaine in the pregnant rat
  124. Hypotension and bradycardia induced by amitriptyline in healthy volunteers
  125. Naming the Cyclic Antidepressants
  126. Possible Teratogenic Effects of Imipramine in the Rat
  127. The effect of experimentally-induced renal failure on accumulation of bupropion and its major basic metabolites in plasma and brain of guinea pigs
  128. Spread-sheet analysis in pharmacokinetic simulations
  129. Analytical Pitfalls with Tricyclic and Newer Antidepressants in Biological Samples
  130. Measurement of haloperidol and reduced haloperidol in human plasma using réversed-phase high-performance liquid chromatography
  131. Stability of Bupropion and its Major Metabolites in Human Plasma
  132. Pharmacokinetics of bupropion and its major basic metabolites in normal subjects after a single dose
  133. Diurnal Variation of α1-Acid Glycoprotein Concentration in Normal Volunteers
  134. Posttraumatic stress disorder: Characteristics and pharmacological response in the veteran population
  135. Cimetidine interaction with amitriptyline
  136. Cerebral and blood pharmacokinetics of imipramine and its active metabolites in the pregnant rat
  137. Quantification of imipramine and its major metabolites in whole blood, brain, and other tissues of the rat by liquid chromatography
  138. Mechanism and Management of Important Psychotherapeutic Drug Interactions
  139. Differences in Diazepam and Oxazepam
  140. The analysis and disposition of imipramine and its active metabolites in man
  141. Pharmacokinetics (2nd edn, revised and expanded), M. Gibaldi and D. Perrier (Vol. 15 of Drugs and the pharmaceutical sciences), Marcel Dekker, New York, 1982
  142. Drug and metabolite concentrations combined in predicting steady-state concentrations from test doses
  143. Dosage regimen design
  144. Hemoperfusion for Imipramine Overdose: Elimination of Active Metabolites