All Stories

  1. The Role of Cholesterol Homeostasis in Diabetic Kidney Disease

    Article • Current Medicinal Chemistry, November 2021, Bentham Science Publishers

    Dr Liang Ma

  2. The Mitochondrion-Targeted Antioxidants in Kidney Disease

    Article • Current Medicinal Chemistry, July 2021, Bentham Science Publishers

    Dr Liang Ma

  3. Synthesis and Biological Evaluation of Novel Substituted 4‐Anilinoquinazolines as Antitumor Agents

    Article • Chemical Biology & Drug Design, October 2020, Wiley

    Dr Liang Ma

  4. Mechanistic Insights of Soluble Uric Acid-related Kidney Disease

    Article • Current Medicinal Chemistry, September 2020, Bentham Science Publishers

    Dr Liang Ma

  5. 2-methylquinazoline derivative F7 as a potent and selective HDAC6 inhibitor protected against rhabdomyolysis-induced acute kidney injury

    Article • PLoS ONE, October 2019, PLOS

    Dr Liang Ma

  6. Microbial and metabolomic remodeling by a formula of Sichuan dark tea improves hyperlipidemia in apoE-deficient mice

    Article • PLoS ONE, July 2019, PLOS

    Dr Liang Ma

  7. Melittin Inducing the Apoptosis of Renal Tubule Epithelial Cells through Upregulation of Bax/Bcl-2 Expression and Activation of TNF-α Signaling Pathway

    Article • BioMed Research International, May 2019, Hindawi Publishing Corporation

    Dr Liang Ma

  8. Mixed micelles loaded with the 5-benzylidenethiazolidine-2,4-dione derivative SKLB023 for efficient treatment of non-alcoholic steatohepatitis

    Article • International Journal of Nanomedicine, May 2019, Dove Medical Press

    Dr Liang Ma

  9. Cigarette smoking as a risk factor for diabetic nephropathy: A systematic review and meta-analysis of prospective cohort studies

    Article • PLoS ONE, February 2019, PLOS

    Dr Liang Ma

  10. Gut microbiota–derived short-chain fatty acids and kidney diseases

    Article • Drug Design Development and Therapy, December 2017, Dove Medical Press

    Dr Liang Ma, Lingzhi Li

  11. Synthesis and biological evaluation of 1, 2, 4-oxadiazole derivatives as novel GPR119 agonists

    Article • Chemical Biology & Drug Design, November 2016, Wiley

    Dr Liang Ma

  12. Design, Synthesis, and Evaluation of in Vitro and In Vivo Anticancer Activity of 4-Substituated Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors

    Article • Journal of Medicinal Chemistry, May 2016, American Chemical Society (ACS)

    Dr Liang Ma

  13. Synthesis, activity, and docking study of phenylthiazole acids as potential agonists of PPARγ

    Article • Drug Design Development and Therapy, May 2016, Dove Medical Press

    Dr Liang Ma

  14. Synthesis, in vitro and in vivo evaluation of novel substituted N-(4-(2-(4-benzylpiperazin-1-yl)ethoxy)phenyl)-N-methyl-quinazolin-4-amines as potent antitumor agents

    Article • Bioorganic & Medicinal Chemistry Letters, April 2016, Elsevier

    Dr Liang Ma

  15. Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer

    Article • Journal of Medicinal Chemistry, February 2016, American Chemical Society (ACS)

    Dr Liang Ma

  16. Synthesis, Activity, and Docking Study of Novel Phenylthiazole-Carboxamido Acid Derivatives as FFA2 Agonists

    Article • Chemical Biology & Drug Design, February 2016, Wiley

    Dr Liang Ma

  17. Therapeutic potential of a synthetic FABP4 inhibitor 8g on atherosclerosis in ApoE-deficient mice: the inhibition of lipid accumulation and inflammation

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    Dr Liang Ma

  18. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity

    Article • Bioorganic & Medicinal Chemistry, July 2015, Elsevier

    Dr Liang Ma

  19. Synthesis and biological evaluation of novel pyrazoline derivatives as potent anti-inflammatory agents

    Article • Bioorganic & Medicinal Chemistry Letters, June 2015, Elsevier

    Dr Liang Ma

  20. Discovery of a Potent 9-Deazaxanthine-based Agent for the Treatment of Obesity-Related Non-alcoholic Fatty Liver Disease

    Article • Chemical Biology & Drug Design, May 2015, Wiley

    Dr Liang Ma

  21. Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases

    Article • European Journal of Medicinal Chemistry, March 2015, Elsevier

    Dr Liang Ma

  22. Scaffold-based design of xanthine as highly potent inhibitors of DPP-IV for improving glucose homeostasis in DIO mice

    Article • Molecular Diversity, February 2015, Springer Science + Business Media

    Dr Liang Ma

  23. Synthesis and Evaluation of Millepachine Amino Acid Prodrugs With Enhanced Solubility as Antitumor Agents

    Article • Chemical Biology & Drug Design, February 2015, Wiley

    Dr Liang Ma

  24. Separation of flavonoids fromMillettia griffithiiwith high-performance counter-current chromatography guided by anti-inflammatory activity

    Article • Journal of Separation Science, December 2014, Wiley

    Dr Liang Ma

  25. Synthesis and biological evaluation of 4-oxoquinoline-3-carboxamides derivatives as potent anti-fibrosis agents

    Article • Bioorganic & Medicinal Chemistry Letters, December 2014, Elsevier

    Dr Liang Ma

  26. Synthesis and lipid-lowering evaluation of 3-methyl-1H-purine-2,6-dione derivatives as potent and orally available anti-obesity agents

    Article • European Journal of Medicinal Chemistry, November 2014, Elsevier

    Dr Liang Ma

  27. Pharmacological Effects of the Water Fraction of Key Components in the Traditional Chinese Prescription Mai Tong Fang on 3T3-L1 Adipocytes and ob/ob Diabetic Mice

    Article • Molecules, September 2014, MDPI AG

    Dr Liang Ma

  28. Synthesis and Biological Evaluation of 5-Nitropyrimidine-2,4-dione Analogues as Inhibitors of Nitric Oxide and iNOS Activity

    Article • Chemical Biology & Drug Design, September 2014, Wiley

    Dr Liang Ma

  29. Protective effect of SKLB010 against d-galactosamine/lipopolysaccharide-induced acute liver failure via nuclear factor-κB signaling pathway in macrophages

    Article • International Immunopharmacology, August 2014, Elsevier

    Dr Liang Ma

  30. Synthesis, structure–activity relationships and biological evaluation of barbigerone analogues as anti-proliferative and anti-angiogenesis agents

    Article • Bioorganic & Medicinal Chemistry Letters, July 2014, Elsevier

    Dr Liang Ma

  31. Synthesis and Biological Evaluation of Novel Urea- and Guanidine-Based Derivatives for the Treatment of Obesity-Related Hepatic Steatosis

    Article • Molecules, May 2014, MDPI AG

    Dr Liang Ma

  32. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents

    Article • Bioorganic & Medicinal Chemistry, April 2014, Elsevier

    Dr Liang Ma

  33. Inclusion complex of barbigerone with hydroxypropyl-β-cyclodextrin: Preparation and in vitro evaluation

    Article • Carbohydrate Polymers, January 2014, Elsevier

    Dr Liang Ma

  34. Synthesis and Biological Evaluation of 3-Methyl-5-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivatives for the Treatment of Diet-Induced Obesity

    Article • Chemical and Pharmaceutical Bulletin, January 2014, Pharmaceutical Society of Japan

    Dr Liang Ma

  35. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors

    Article • Bioorganic & Medicinal Chemistry, November 2013, Elsevier

    Dr Liang Ma

  36. Identification of honokiol metabolites in rats by the method of stable isotope cluster technique and ultra-high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry

    Article • Journal of Chromatography B, July 2013, Elsevier

    Dr Liang Ma

  37. Identification of metabolites of honokiol in rat urine using 13C stable isotope labeling and liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

    Article • Journal of Chromatography A, June 2013, Elsevier

    Dr Liang Ma

  38. SKLB023 Blocks Joint Inflammation and Cartilage Destruction in Arthritis Models via Suppression of Nuclear Factor-Kappa B Activation in Macrophage

    Article • PLoS ONE, February 2013, PLOS

    Dr Liang Ma

  39. Calcium carbonate microspheres as carriers for the anticancer drug camptothecin

    Article • Materials Science and Engineering C, December 2012, Elsevier

    Dr Liang Ma

  40. Synthesis and Biological Evaluation of 5-Benzylidenepyrimidine-2,4,6(1 H ,3 H ,5 H )-trione Derivatives for the Treatment of Obesity-Related Nonalcoholic Fatty Liver Disease

    Article • Journal of Medicinal Chemistry, November 2012, American Chemical Society (ACS)

    Dr Liang Ma

  41. Semi-Synthesis and Biological Evaluation of 1,2,3-Triazole-Based Podophyllotoxin Congeners as Potent Antitumor Agents Inducing Apoptosis in HepG2 Cells

    Article • Archiv der Pharmazie, September 2012, Wiley

    Dr Liang Ma

  42. Design, synthesis, and structure–activity relationship studies of novel millepachine derivatives as potent antiproliferative agents

    Article • European Journal of Medicinal Chemistry, August 2012, Elsevier

    Dr Liang Ma

  43. Design, Synthesis, and Anti-Proliferative Evaluation of [1,1′-biphenyl]-4-ols as Inhibitor of HUVEC Migration and Tube Formation

    Article • Molecules, July 2012, MDPI AG

    Dr Liang Ma

  44. Design, synthesis and biological evaluation of thiazole- and indole-based derivatives for the treatment of type II diabetes

    Article • European Journal of Medicinal Chemistry, June 2012, Elsevier

    Dr Liang Ma

  45. Synthesis and Evaluation of 5-Benzylidenethiazolidine-2,4-dione Derivatives for the Treatment of Non-Alcoholic Fatty Liver Disease

    Article • Archiv der Pharmazie, April 2012, Wiley

    Dr Liang Ma

  46. Synthesis and biological evaluation of novel dimethyl[1,1′-biphenyl]-2,2′-dicarboxylate derivatives containing thiazolidine-2,4-dione for the treatment of concanavalin A-induced acute liver injury of BALB/c mice

    Article • European Journal of Medicinal Chemistry, December 2011, Elsevier

    Dr Liang Ma

  47. Structural Modification of Honokiol, a Biphenyl Occurring in Magnolia officinalis: the Evaluation of Honokiol Analogues as Inhibitors of Angiogenesis and for Their Cytotoxicity and Structure–Activity Relationship

    Article • Journal of Medicinal Chemistry, October 2011, American Chemical Society (ACS)

    Dr Liang Ma

  48. Development and validation of a UPLC–MS/MS method for quantification of SKLB010, an investigational anti-inflammatory compound, and its application to pharmacokinetic studies in beagle dogs

    Article • Journal of Pharmaceutical and Biomedical Analysis, September 2011, Elsevier

    Dr Liang Ma

  49. A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance

    Article • European Journal of Pharmacology, June 2011, Elsevier

    Dr Liang Ma

  50. Synthesis and biological activity of novel barbituric and thiobarbituric acid derivatives against non-alcoholic fatty liver disease

    Article • European Journal of Medicinal Chemistry, June 2011, Elsevier

    Dr Liang Ma

  51. Synthesis and Biological Evaluation of Novel 5-Benzylidenethiazolidine-2,4-dione Derivatives for the Treatment of Inflammatory Diseases

    Article • Journal of Medicinal Chemistry, April 2011, American Chemical Society (ACS)

    Dr Liang Ma

  52. (Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a Novel Readily Available and Orally Active Glitazone, Attenuates the Bleomycin-Induced Pulmonary Fibrosis in Vivo

    Article • Biological and Pharmaceutical Bulletin, January 2011, Pharmaceutical Society of Japan

    Dr Liang Ma

  53. (Z)-5-(4-methoxybenzylidene) thiazolidine-2, 4-dione ameliorates the adjuvant-induced arthritis via inhibiting the migration of macrophage and down-regulating the cytokine mRNA expression

    Article • International Immunopharmacology, November 2010, Elsevier

    Dr Liang Ma

  54. Discovery of ( Z )-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a Readily Available and Orally Active Glitazone for the Treatment of Concanavalin A-Induced Acute Liver Injury of BALB/c Mice

    Article • Journal of Medicinal Chemistry, January 2010, American Chemical Society (ACS)

    Dr Liang Ma

  55. Rapid separation and identification of major constituents in Pseudolarix kaempferi by ultra-performance liquid chromatography coupled with electrospray and quadrupole time-of-flight tandem mass spectrometry

    Article • Rapid Communications in Mass Spectrometry, November 2009, Wiley

    Dr Liang Ma