All Stories

  1. Rethinking HIV antibody testing in children aged 18-24 months in the OPPTIM study conducted in Johannesburg, South Africa 2018-2021
  2. Vaginal Microbiota and Cytokines Among Pregnant and Breastfeeding Women in Clinical Trials of the Dapivirine Vaginal Ring and Oral Tenofovir Disoproxil Fumarate/Emtricitabine
  3. Letter Reply to “Mind the Postpartum Trough: Closing the Clofazimine Exposure Gap After Delivery in Rifampicin-Resistant Tuberculosis”
  4. Rethinking HIV antibody testing in children aged 18-24 months in the OPPTIM study conducted in Johannesburg, South Africa 2018-2021
  5. Health system and household costs of preventive treatment delivery for children exposed to multidrug-resistant tuberculosis in South Africa
  6. Pharmacokinetics and Safety of Clofazimine in Women With Rifampicin-resistant Tuberculosis During Pregnancy and the Postpartum Period: Results From IMPAACT P1026s
  7. Clot twist – D-dimer analysis of healthy adults receiving heterologous or homologous booster COVID-19 vaccine after a single prime dose of Ad26.COV2.S in a phase II randomised open-label trial, BaSiS
  8. Safety and immunogenicity of investigational tuberculosis vaccine M72/AS01E–4 in people living with HIV in South Africa: an observer-blinded, randomised, controlled, phase 2 trial
  9. Factors Predictive of Early Discontinuation of Preventive Treatment in Children With Household Exposure to Multidrug-resistant Tuberculosis
  10. Characterizing the HIV care continuum among children and adolescents with HIV in eastern and southern Africa in the era of “Universal Test and Treat”: A systematic review and meta‐analysis
  11. Bone Mineral Content, Growth, and Renal Health of Infants With Perinatal Exposure to Maternal Dolutegravir Versus Efavirenz and Tenofovir Disoproxil Fumarate Versus Tenofovir Alafenamide: The Randomized IMPAACT 2010 (VESTED) Trial
  12. Risk of tuberculosis infection in young children exposed to multidrug-resistant tuberculosis in the TB-CHAMP multi-site randomised controlled trial
  13. BCG Revaccination for the Prevention of Mycobacterium tuberculosis Infection
  14. Pharmacokinetics and Safety of Levofloxacin for Treatment of Rifampicin-Resistant Tuberculosis During Pregnancy and the Postpartum Period: Results from IMPAACT P1026s
  15. Acceptability of a 250 mg levofloxacin formulation in children receiving TB preventive treatment
  16. Vaccine Utilization and Timing of Administration in Pregnant Women: A South African Perspective
  17. Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis
  18. The need to avert emergent resistance to dolutegravir in children and adolescents with HIV
  19. Safety and immunogenicity of Ad26.COV2.S in adolescents: Phase 2 randomized clinical trial
  20. A Meta-Analysis of Levofloxacin for Contacts of Multidrug-Resistant Tuberculosis
  21. Burden of Lassa fever disease in pregnant women and children and options for prevention
  22. Levofloxacin Preventive Treatment in Children Exposed to MDR Tuberculosis
  23. Immunogenicity and safety following a homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine with Matrix-M TM adjuvant (NVX-CoV2373) versus a primary series in people living with and without HIV-1 i...
  24. Measles–Rubella Microarray Patches Phase III Clinical Trial Framework: Proposal and Considerations
  25. South African Parents’ and Grandparents’ Perspectives on the Acceptability of Implant Delivery of Treatment to Young Children with HIV
  26. Brief Report: Subsequent Pregnancies in the IMPAACT 2010/VESTED Trial: High Rate of Adverse Outcomes in Women Living With HIV
  27. Markers of Maternal Bone and Renal Toxicity Through 50 Weeks Postpartum: IMPAACT 2010 (VESTED) Trial
  28. Brief Report: Characterizing HIV Drug Resistance in Cases of Vertical Transmission in the VESTED Randomized Antiretroviral Treatment Trial
  29. Acceptability of the Dapivirine Vaginal Ring and Daily Oral Pre-exposure Prophylaxis (PrEP) during Pregnancy in Malawi, South Africa, Uganda, and Zimbabwe
  30. Dolutegravir- Versus Efavirenz-Based Treatment in Pregnancy: Impact on Red Blood Cell Folate Concentrations in Pregnant Women and Their Infants
  31. Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants
  32. Assessment of weight gain in adult patients living with HIV receiving first‐line dolutegravir‐based or efavirenz‐based ART regimens in routine care clinics in Tshwane district, South Africa: An observational study
  33. Effects of preterm birth, maternal ART and breastfeeding on 24-month infant HIV-free survival in a randomized trial
  34. Clot Twist – D-dimer analysis of healthy adults receiving heterologous or homologous booster COVID-19 vaccine after a single prime dose of Ad26.COV2.S in a phase II randomised open-label trial, BaSiS
  35. Obstetric and neonatal outcomes in South Africa
  36. Final 192-Week Efficacy and Safety Results of the ADVANCE Trial, Comparing 3 First-line Antiretroviral Regimens
  37. Weight Changes and Adverse Pregnancy Outcomes With Dolutegravir- and Tenofovir Alafenamide Fumarate–Containing Antiretroviral Treatment Regimens During Pregnancy and Postpartum
  38. DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy
  39. More Frequent HIV Viral Load Testing With Point-Of-Care Tests Detects Elevated Viral Load Earlier in Postpartum HIV-Positive Women in a Randomized Controlled Trial in Two Clinics in Johannesburg, South Africa
  40. Translating the consent form is the tip of the iceberg: using cognitive interviews to assess the barriers to informed consent in South African health facilities
  41. Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants
  42. Preferences for onward health data use in the electronic age among maternity patients and providers in South Africa: a qualitative study
  43. Acceptability of the Dapivirine Vaginal Ring and Oral Truvada Among African Users in Late-Stage of Pregnancy
  44. Safety surveillance for PrEP in pregnant and breastfeeding women
  45. Population Pharmacokinetic Modeling of Dolutegravir to Optimize Pediatric Dosing in HIV-1-Infected Infants, Children, and Adolescents
  46. Potential for Maternally Administered Vaccine for Infant Group B Streptococcus
  47. The burden, prevention and care of infants and children with congenital anomalies in sub-Saharan Africa: A scoping review
  48. ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19
  49. Efficacy and safety of three antiretroviral therapy regimens started in pregnancy up to 50 weeks post partum: a multicentre, open-label, randomised, controlled, phase 3 trial
  50. Efficacy of primary series AZD1222 (ChAdOx1 nCoV-19) vaccination against SARS-CoV-2 variants of concern: Final analysis of a randomized, placebo-controlled, phase 1b/2 study in South African adults (COV005)
  51. Durability of ChAdOx1 nCoV-19 (AZD1222) vaccine and hybrid humoral immunity against variants including omicron BA.1 and BA.4 6 months after vaccination (COV005): a post-hoc analysis of a randomised, phase 1b–2a trial
  52. Longitudinal IgA and IgG Response, and ACE2 Binding Blockade, to Full-Length SARS-CoV-2 Spike Protein Variants in a Population of Black PLWH Vaccinated with ChAdOx1 nCoV-19
  53. Novavax NVX-COV2373 triggers neutralization of Omicron sub-lineages
  54. High prevalence of SARS-CoV-2 antibodies in pregnant women after the second wave of infections in the inner-city of Johannesburg, Gauteng Province, South Africa
  55. Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages
  56. T-cell responses induced by ChAdOx1 nCoV-19 (AZD1222) vaccine to wild-type severe acute respiratory syndrome coronavirus 2 among people with and without HIV in South Africa
  57. Acceptability of Implants for HIV Treatment in Young Children: Perspectives of Health Care Providers in Johannesburg, South Africa
  58. Ambient temperature during pregnancy and risk of maternal hypertensive disorders: A time-to-event study in Johannesburg, South Africa
  59. Antiretroviral choice and severe disease predict poorer neuropsychological outcomes in HIV+ children from Africa
  60. HIV treatment success in children and adolescents with HIV
  61. SARS-CoV-2 infection in Africa: a systematic review and meta-analysis of standardised seroprevalence studies, from January 2020 to December 2021
  62. Maternal and infant renal safety following tenofovir disoproxil fumarate exposure during pregnancy in a randomized control trial
  63. Efficacy of the AZD1222 (ChAdOx1 nCoV-19) COVID-19 Vaccine Against SARS-CoV-2 Variants of Concern
  64. Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages
  65. Approaches to accelerating the study of new antiretrovirals in pregnancy
  66. Immunogenicity and safety of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine in people living with and without HIV-1 infection: a randomised, controlled, phase 2A/2B trial
  67. SARS-CoV-2 infection in Africa: A systematic review and meta-analysis of standardised seroprevalence studies, from January 2020 to December 2021
  68. Combination HIV prevention reduces orphanhood in Uganda
  69. A public health approach to drug use crucial to ending AIDS
  70. Global SARS-CoV-2 seroprevalence: a systematic review and meta-analysis of standardized population-based studies from Jan 2020-May 2022
  71. The predicted risk of adverse pregnancy outcomes as a result of treatment-associated obesity in a hypothetical population receiving tenofovir alafenamide/emtricitabine/dolutegravir, tenofovir disoproxil fumarate/emtricitabine/dolutegravir or tenofovir ...
  72. Pooled Prevalence of Adverse Pregnancy and Neonatal Outcomes in Malawi, South Africa, Uganda, and Zimbabwe: Results From a Systematic Review and Meta-Analyses to Inform Trials of Novel HIV Prevention Interventions During Pregnancy
  73. Challenges in recruiting children to a multidrug-resistant TB prevention trial
  74. Pharmacokinetics and safety of high-dose rifampicin in children with TB: the Opti-Rif trial
  75. Ethically designing research to inform multidimensional, rapidly evolving policy decisions: Lessons learned from the PROMISE HIV Perinatal Prevention Trial
  76. Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: an interim analysis of a randomised, double-blind, placebo-controlled, phase 1B/2A trial
  77. Effect on growth of exposure to maternal antiretroviral therapy in breastmilk versus extended infant nevirapine prophylaxis among HIV-exposed perinatally uninfected infants in the PROMISE randomized trial
  78. Effects of preconception antiretroviral therapy in placenta development and pregnancy outcomes
  79. Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant
  80. Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant
  81. Etravirine in treatment-experienced HIV-1-infected children 1 year to less than 6 years of age
  82. Brief Report: Impact of ART on Maternal Health After Cessation of Breastfeeding
  83. Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAAC...
  84. Assessing pregnancy and neonatal outcomes in Malawi, South Africa, Uganda, and Zimbabwe: Results from a systematic chart review
  85. ChAdOx1 nCoV-19 (AZD1222) Vaccine in People Living With and Without HIV
  86. Preliminary Efficacy of the NVX-CoV2373 Covid-19 Vaccine Against the B.1.351 Variant
  87. Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
  88. Safety and efficacy of the ChAdOx1 nCoV-19 (AZD1222) Covid-19 vaccine against the B.1.351 variant in South Africa
  89. Unexpected interactions between dolutegravir and folate: randomized trial evidence from South Africa
  90. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
  91. Single Dose Administration, And The Influence Of The Timing Of The Booster Dose On Immunogenicity and Efficacy Of ChAdOx1 nCoV-19 (AZD1222) Vaccine
  92. Dolutegravir with emtricitabine and tenofovir alafenamide or tenofovir disoproxil fumarate versus efavirenz, emtricitabine, and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection (ADVANCE): week 96 results from a randomised, phase 3...
  93. Safety and immunogenicity of a parenteral trivalent P2-VP8 subunit rotavirus vaccine: a multisite, randomised, double-blind, placebo-controlled trial
  94. Pregnancy Outcomes of Women Conceiving on Antiretroviral Therapy (ART) Compared to Those Commenced on ART During Pregnancy
  95. Virologic response to efavirenz-based first-line antiretroviral therapy in children with previous exposure to antiretrovirals to prevent mother-to-child transmission
  96. Pharmacokinetics and Safety of a Raltegravir-Containing Regimen in Children Aged 4 Weeks to 2 Years Living With Human Immunodeficiency Virus and Receiving Rifampin for Tuberculosis
  97. COVID-19 in Africa: care and protection for frontline healthcare workers
  98. Abacavir Exposure in Children Cotreated for Tuberculosis with Rifampin and Superboosted Lopinavir-Ritonavir
  99. Earlier Antiretroviral Therapy Initiation and Decreasing Mortality Among HIV-infected Infants Initiating Antiretroviral Therapy Within 3 Months of Age in South Africa, 2006–2017
  100. The impact of short term Antiretroviral Therapy (ART) interruptions on longer term maternal health outcomes—A randomized clinical trial
  101. African Multi-Site 2-Year Neuropsychological Study of School-Age Children Perinatally Infected, Exposed, and Unexposed to Human Immunodeficiency Virus
  102. Association between HIV antiretroviral therapy and preterm birth based on antenatal ultrasound gestational age determination
  103. Neurodevelopmental delay: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data
  104. Current perspectives on paediatric HIV management from the Mexico International Aids Society Conference, 2019
  105. Inclusion of pregnant women in antiretroviral drug research: what is needed to move forwards?
  106. Association between caregiver depression symptoms and child executive functioning. Results from an observational study carried out in four sub-Saharan countries
  107. Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV
  108. Why South Africa urgently needs to support the development of pregnancy exposure registries
  109. What Should We Do When HIV-positive Children Fail First-line Combination Antiretroviral Therapy? A Comparison of 4 ART Management Strategies
  110. African Multi-Site Two-Year Longitudinal Study of Neurocognition in HIV Infected/Affected Children
  111. 287: Diagnostic accuracy of clinical newborn assessment versus ultrasound to define preterm birth: the PROMISE trial
  112. Levofloxacin versus placebo for the prevention of tuberculosis disease in child contacts of multidrug-resistant tuberculosis: study protocol for a phase III cluster randomised controlled trial (TB-CHAMP)
  113. Mortality and losses to follow‐up among adolescents living with HIV in the IeDEA global cohort collaboration
  114. Maternal health outcomes among HIV-infected breastfeeding women with high CD4 counts: results of a treatment strategy trial
  115. Lamivudine monotherapy as a holding regimen for HIV-positive children
  116. Building capacity in neurodevelopment assessment of children in sub-Saharan Africa: A quality assurance model to implement standardized neurodevelopment testing
  117. HIV retesting in pregnant women in South Africa: Outcomes of a quality improvement project targeting health systems’ weaknesses
  118. Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis
  119. High loss to follow-up of children on antiretroviral treatment in a primary care HIV clinic in Johannesburg, South Africa
  120. Validity of Neuropsychological Testing in Young African Children Affected by HIV
  121. Thank you from HMPG and the editors
  122. Lamivudine monotherapy in children and adolescents: The devil is in the detail
  123. Neuropsychological performance in African children with HIV enrolled in a multi-site anti-retroviral clinical trial
  124. Decline in CD4 T lymphocytes with monotherapy bridging strategy for non-adherent adolescents living with HIV infection: Results of the IMPAACT P1094 randomized trial
  125. The interaction between equipoise and logistics in clinical trials: A case study
  126. Cutting the cost of South African antiretroviral therapy using newer, safer drugs
  127. Cutting the cost of South African antiretroviral therapy using newer, safer drugs
  128. The Challenge of and Opportunities for Transitioning and Maintaining a Continuum of Care Among Adolescents and Young Adults Living with HIV in Resource Limited Settings
  129. Nevirapine- Versus Lopinavir/Ritonavir-Based Antiretroviral Therapy in HIV-Infected Infants and Young Children: Long-term Follow-up of the IMPAACT P1060 Randomized Trial
  130. Views of Medical Doctors Regarding the 2013 WHO Adult HIV Treatment Guidelines Indicate Variable Applicability for Routine Patient Monitoring, for Their Family Members and for Themselves, in South-Africa
  131. CD4+ and viral load outcomes of antiretroviral therapy switch strategies after virologic failure of combination antiretroviral therapy in perinatally HIV-infected youth in the United States
  132. Outcomes in treatment with darunavir/ritonavir in ART-experienced paediatric patients
  133. Time to implement 9-month infant HIV testing in South Africa
  134. Outcomes of Infants Starting Antiretroviral Therapy in Southern Africa, 2004–2012
  135. Paradoxical tuberculosis‐associated immune reconstitution inflammatory syndrome in children
  136. HIV and adolescents: focus on young key populations
  137. Providing comprehensive health services for young key populations: needs, barriers and gaps
  138. Virologic Failure Among Children Taking Lopinavir/Ritonavir-containing First-line Antiretroviral Therapy in South Africa
  139. Focus on adolescents with HIV and AIDS
  140. Microbiological investigation for tuberculosis among HIV-infected children in Soweto, South Africa
  141. Evaluation of Parent-Child Pairs on Antiretroviral Therapy in Separate Adult and Pediatric Clinics
  142. Frequency of stavudine substitution due to toxicity in children receiving antiretroviral treatment in sub-Saharan Africa
  143. Predictors of loss to follow-up among children in the first and second years of antiretroviral treatment in Johannesburg, South Africa
  144. Cost and outcomes of paediatric antiretroviral treatment in South Africa
  145. Antiretroviral treatment, management challenges and outcomes in perinatally HIV-infected adolescents
  146. Lamivudine Monotherapy as a Holding Strategy in HIV-Infected Children in South Africa
  147. Antiretroviral Therapy Outcomes in HIV-Infected Children after Adjusting Protease Inhibitor Dosing during Tuberculosis Treatment
  148. High prevalence of childhood multi-drug resistant tuberculosis in Johannesburg, South Africa: a cross sectional study
  149. Lopinavir Exposure is Insufficient in Children Given Double Doses of Lopinavir/Ritonavir during Rifampicin-Based Treatment for Tuberculosis