All Stories

  1. Evolution of termination codons of proteins and the TAG-TGA paradox
  2. Use of Publication Dynamics to Distinguish Cancer Genes and Bystander Genes
  3. Wnt Inhibitory Factor 1 Binds to and Inhibits the Activity of Sonic Hedgehog
  4. Miguel Llinás and the Structure of the Kringle Fold
  5. Exon Shuffling Played a Decisive Role in the Evolution of the Genetic Toolkit for the Multicellular Body Plan of Metazoa
  6. Use of signals of positive and negative selection to distinguish cancer genes and passenger genes
  7. Fold class and evolutionary mobility of protein modules
  8. The Arg244His missense mutation in SDHB-1 leads to altered metabolism in Caenorhabditis elegans: a new disease model
  9. Exon skipping-rich transcriptomes of animals reflect the significance of exon-shuffling in metazoan proteome evolution
  10. Influence of WFIKKN 1 on BMP 1‐mediated activation of latent myostatin
  11. The Mstn cmpt-Dl1abc mutation impairs secretion of promyostatin
  12. Putative extremely high rate of proteome innovation in lancelets might be explained by high rate of gene prediction errors
  13. Identification and Correction of Erroneous Protein Sequences in Public Databases
  14. Wnts grasp the WIF domain of Wnt Inhibitory Factor 1 at two distinct binding sites
  15. K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin
  16. FixPred: a resource for correction of erroneous protein sequences
  17. Both LCCL-domains of human CRISPLD2 have high affinity for lipid A
  18. MisPred: a resource for identification of erroneous protein sequences in public databases
  19. Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2
  20. Exons and Protein Modules
  21. Domain Architecture Evolution of Metazoan Proteins
  22. Characterization of a Wnt-binding site of the WIF-domain of Wnt inhibitory factor-1
  23. Biological functions of the WAP domain-containing multidomain proteins WFIKKN1 and WFIKKN2
  24. Correction: Nagy, A., et al. Reassessing Domain Architecture Evolution of Metazoan Proteins: Major Impact of Gene Prediction Errors. Genes 2011, 2, 449-501.
  25. Reassessing Domain Architecture Evolution of Metazoan Proteins: The Contribution of Different Evolutionary Mechanisms
  26. Reassessing Domain Architecture Evolution of Metazoan Proteins: Major Impact of Errors Caused by Confusing Paralogs and Epaktologs
  27. Reassessing Domain Architecture Evolution of Metazoan Proteins: Major Impact of Gene Prediction Errors
  28. WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity
  29. Agrin Binds BMP2, BMP4 and TGFβ1
  30. Identifying protein-coding genes in genomic sequences
  31. The second von Willebrand type A domain of cochlin has high affinity for type I, type II and type IV collagens
  32. Alternative Splicing: Evolution
  33. Exons: Shuffling
  34. Exons and Protein Modules
  35. Introns: Phase Compatibility
  36. Collagen-binding domains of gelatinase A and thrombospondin-derived peptides impede endocytic clearance of active gelatinase A and promote HT1080 fibrosarcoma cell invasion
  37. Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
  38. Quality control of gene predictions
  39. Comment on "Tequila, a Neurotrypsin Ortholog, Regulates Long-Term Memory Formation in Drosophila"
  40. A general theory of gene sharing
  41. Exons: Shuffling
  42. Alternative Splicing: Evolution
  43. Introns: Phase Compatibility
  44. Exons and Protein Modules
  45. Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein
  46. NMR structure of the WIF domain from human WIF-1
  47. NMR Structure of the WIF Domain of the Human Wnt-Inhibitory Factor-1
  48. Modules, multidomain proteins and organismic complexity
  49. Hydroxamate-based peptide inhibitors of matrix metalloprotease 2
  50. Xenolog
  51. Coevolution of Protein Residues
  52. Alignment Score
  53. Protein Domain
  54. Multidomain Protein
  55. DNA-Protein Coevolution
  56. Exon Shuffling
  57. Synonymous Mutation (Silent Mutation)
  58. Gap Penalty
  59. Homology
  60. Protein Module
  61. Module Shuffling
  62. Exon
  63. Homologous Genes
  64. Protein-Protein Coevolution
  65. Modular Protein
  66. Sequence Similarity Search
  67. Non-Synonymous Mutation
  68. BLOSUM (BLOSUM Matrix)
  69. Xenolog (Xenologue)
  70. Epaktolog (Epaktologue)
  71. Pseudoparalog (pseudoparalogue)
  72. BLOSUM Matrix
  73. Horizontal Gene Transfer
  74. Mosaic Protein
  75. Nonsynonymous Mutation
  76. PAM Matrix of Nucleotide Substitutions
  77. Paralog
  78. Homology
  79. Modular Protein
  80. Coevolution (Molecular Coevolution)
  81. Sequence Similarity Search
  82. Multidomain Protein
  83. Coevolution of Protein Residues
  84. Module Shuffling
  85. Gap Penalty
  86. Protein Domain
  87. Homologous Genes
  88. Exon Shuffling
  89. Alignment Score
  90. DNA-Protein Coevolution
  91. Protein-Protein Coevolution
  92. Synonymous Mutation (Silent Mutation)
  93. Exon
  94. Protein Module
  95. Protein Family
  96. Dayhoff Amino Acid Substitution Matrix (PAM Matrix, Percent Accepted Mutation Matrix)
  97. PAM Matrix of Nucleotide Substitutions (Point Accepted Mutations)
  98. Paralog (Paralogue)
  99. Protein Family
  100. Dayhoff Amino Acid Substitution Matrix (PAM Matrix, Percent Accepted Mutation Matrix)
  101. Insertion of spliceosomal introns in proto-splice sites: the case of secretory signal peptides
  102. Evidence that human genes of modular proteins have retained significantly more ancestral introns than their fly or worm orthologues
  103. Mutations in the COCH gene are a frequent cause of autosomal dominant progressive cochleo-vestibular dysfunction, but not of Meniere's disease
  104. NMR structure of the NTR domain from human PCOLCE1
  105. Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein
  106. Expression and characterization of the olfactomedin domain of human myocilin
  107. Modular assembly of genes and the evolution of new functions
  108. Structural characterization of the second TSP1-module of human thrombospondin
  109. The First Fibronectin Type II Module from Human Matrix Metalloproteinase 2
  110. Distinct Expression Pattern of Two Related Human Proteins Containing Multiple Types of Protease-Inhibitory Modules
  111. The Col-1 Module of Human Matrix Metalloproteinase-2 (MMP-2): Structural/Functional Relatedness between Gelatin-Binding Fibronectin Type II Modules and Lysine-Binding Kringle Domains
  112. NMR structure of the LCCL domain
  113. Origin of fibronectin type II (FN2) modules: Structural analyses of distantly-related members of the kringle family idey the kringle domain of neurotrypsin as a potential link between FN2 domains and kringles
  114. The Third Fibronectin Type II Module from Human Matrix Metalloproteinase 2
  115. Localization of Disulfide Bonds in the Frizzled Module of Ror1 Receptor Tyrosine Kinase
  116. Were protein internal repeats formed by ‘bricolage’?
  117. Involvement of Fibronectin Type II Repeats in the Efficient Inhibition of Gelatinases A and B by Long-chain Unsaturated Fatty Acids
  118. Unique functional composition of metazoan genomes
  119. The LCCL module
  120. The WIF module
  121. THE SECOND TYPE II MODULE FROM HUMAN MATRIX METALLOPROTEINASE 2
  122. The PAN module: the N-terminal domains of plasminogen and hepatocyte growth factor are homologous with the apple domains of the prekallikrein family and with a novel domain found in numerous nematode proteins
  123. The second type II module from human matrix metalloproteinase 2: structure, function and dynamics
  124. Genome evolution and the evolution of exon-shuffling — a review
  125. The NTR module: Domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases
  126. The gelatin-binding site of the second type-II domain of gelatinase �A/MMP-2
  127. Amoebapore homologs of Caenorhabditis elegans
  128. A deletion in the myostatin gene causes the compact ( Cmpt ) hypermuscular mutation in mice
  129. Apolipoprotein(a): A Puzzling Evolutionary Story
  130. Exon shuffling and other ways of module exchange
  131. [12] Consensus approaches in detection of distant homologies
  132. The SEA module: A new extracellular domain associated withO-glycosylation
  133. Sequences and topology
  134. Introns and exons
  135. Agrin-like proteins of the neuromuscular junction
  136. REFINED SOLUTION STRUCTURE AND LIGAND-BINDING PROPERTIES OF PDC-109 DOMAIN B. A COLLAGEN-BINDING TYPE II DOMAIN
  137. Significance of exon-shuffling in the evolution of extracellular proteolytic systems
  138. Functions of agrin and agrin-related proteins
  139. [1] Modular design of proteases of coagulation, fibrinolysis, and complement activation: Implications for protein engineering and structure-function studies
  140. Structure, function and evolution of mosaic proteins
  141. A family of laminin-related proteins controlling ectodermal differentiation in Drosophila
  142. Refined solution structure and ligand-binding properties of PDC-109 domain b
  143. Laminin A-related domains in crb protein of Drosophila and their possible role in epithelial polarization
  144. Modular exchange principles in proteins
  145. Evidence for the involvement of type II domains in collagen binding by 72 kDa type IV procollagenase
  146. Conformation of Lys-plasminogen and the kringle 1-3 fragment of plasminogen analyzed by small-angle neutron scattering
  147. Exons - original building blocks of proteins?
  148. Sequence-specific proton NMR assignments and structural characterization of bovine seminal fluid protein PDC-109 domain b
  149. The collagen-binding site of type-II units of bovine seminal fluid protein PDC-109 and fibronectin
  150. Evolutionary Assembly of Blood Coagulation Proteins
  151. Homology of a domain of the growth hormone/prolactin receptor family with type III modules of fibronectin
  152. Homology of cytotoxic protein of eosinophilic leukocytes with IgE receptor Fcϵ RII: Implications for its structure and function
  153. Detecting distant homologies of mosaic proteins
  154. Homology of human pancreatic stone protein with animal lectins
  155. 44 Homologies of plasma proteases: Implications for their structure, function and evolution
  156. 245 Different shapes and secondary struture of human glu- and lys-plasminogen
  157. Analysis of the aliphatic 1H-NMR spectrum of plasminogen kringle 4. A comparative study of human, porcine, bovine and chicken homologs
  158. Detecting homology of distantly related proteins with consensus sequences
  159. Intron-dependent evolution: Preferred types of exons and introns
  160. Is lung surfactant protein a lectin–collagen hybrid?
  161. The aromatic 1H-NMR spectrum of plasminogen kringle 4. A comparative study of human, porcine and bovine homologs
  162. The krigle 4 domain of chicken plasminogen
  163. Proximity of the catalytic region and the kringle 2 domain in the closed conformer of plasminogen
  164. Chemical modification and nuclear magnetic resonance studies on human plasminogen kringle 4. Assignment of tyrosine and histidine resonances to specific residues in the sequence
  165. Comments on 'Purification and properties of plasminogen activators from epithelial cells', by A. Electricwala and T. Atkinson
  166. Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules
  167. Analysis and identification of aromatic signals in the proton magnetic resonance spectrum of the kringle 4 fragment from human plasminogen
  168. .beta.(Leu121-Lys122) segment of fibrinogen is in a region essential for plasminogen binding by fibrin fragment E
  169. Common evolutionary origin of the fibrin-binding structures of fibronectin and tissue-type plasminogen activator
  170. Location of plasminogen-binding sites in human fibrin(ogen)
  171. Structure of the omega-aminocarboxylic acid-binding sites of human plasminogen. Arginine 70 and aspartic acid 56 are essential for binding of ligand by kringle 4.
  172. Origin of the Selectivity of alpha-Dicarbonyl Reagents for Arginyl Residues of Anion-Binding Sites
  173. Identification of the C-1-Phosphate-Binding Arginine Residue of Rabbit-Muscle Aldolase. Isolation of 1,2-Cyclohexanedione-Labeled Peptide by Chemisorption Chromatography
  174. Aldolase-catalysed inactivation of glyceraldehyde-3-phosphate dehydrogenase
  175. Role of Nascent alpha-Ketoaldehyde in Substrate-Dependent Oxidative Inactivation of Aldolase
  176. Decreased Heparin Sensitivity of Cyclohexanedione-Modified Thrombin
  177. Histone III. VI. Two forms of calf thymus histone III.
  178. Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues
  179. Identification of functional arginine residues in ribonuclease A and lysozyme
  180. Histone III
  181. Effect of amino acid starvation on constitutive synthesis of histidine mRNA