All Stories

  1. Volatile allosteric antagonists of mosquito odorant receptors inhibit human-host attraction

    Article • Journal of Biological Chemistry, January 2021, Elsevier

    Dr. Stefan Schulz, Professor Kostas Iatrou

  2. Volatile allosteric antagonists of mosquito odorant receptors inhibit normal odor-dependent behaviors

    Article • April 2020, Cold Spring Harbor Laboratory Press

    Professor Kostas Iatrou

  3. Identification of novel bioinspired synthetic mosquito repellents by combined ligand-based screening and OBP-structure-based molecular docking

    Article • Insect Biochemistry and Molecular Biology, July 2018, Elsevier

    Professor Kostas Iatrou

  4. Odorant-binding protein-based identification of natural spatial repellents for the African malaria mosquito Anopheles gambiae

    Article • Insect Biochemistry and Molecular Biology, May 2018, Elsevier

    Professor Kostas Iatrou

  5. Positive Allosteric Modulation of Insect Olfactory Receptor Function by ORco Agonists

    Article • Frontiers in Cellular Neuroscience, December 2016, Frontiers

    Professor Kostas Iatrou

  6. Bombyx mori nucleopolyhedrovirus lef8 gene: effects of deletion and implications for gene transduction applications

    Article • Journal of General Virology, March 2016, Society for General Microbiology

    Professor Kostas Iatrou

  7. A comprehensive analysis of the chorion locus in silkmoth

    Article • Scientific Reports, November 2015, Nature

    Professor Kostas Iatrou

  8. Construction, complete sequence, and annotation of a BAC contig covering the silkworm chorion locus

    Article • Scientific Data, November 2015, Nature

    Professor Kostas Iatrou

  9. Inhibition of Anopheles gambiae Odorant Receptor Function by Mosquito Repellents

    Article • Journal of Biological Chemistry, February 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Kostas Iatrou

  10. Chorion Genes: A Landscape of Their Evolution, Structure, and Regulation

    Article • Annual Review of Entomology, January 2015, Annual Reviews

    Professor Kostas Iatrou

  11. Expression of a Highly Antigenic and Native-Like Folded Extracellular Domain of the Human α1 Subunit of Muscle Nicotinic Acetylcholine Receptor, Suitable for Use in Antigen Specific Therapies for Myasthenia Gravis

    Article • PLOS One, December 2013, PLOS

    Professor Kostas Iatrou

  12. Crystal and Solution Studies of the “Plus-C” Odorant-binding Protein 48 from Anopheles gambiae

    Article • Journal of Biological Chemistry, November 2013, Elsevier

    Professor Kostas Iatrou

  13. Functional Characterization of a Juvenile Hormone Esterase Related Gene in the Moth Sesamia nonagrioides through RNA Interference

    Article • PLOS One, September 2013, PLOS

    Professor Kostas Iatrou

  14. A simple technique to enhance the humoral immune response to intracellular protein antigens in genetic immunizations

    Article • Journal of Immunological Methods, January 2013, Elsevier

    Professor Kostas Iatrou

  15. BmVMP90, a large vitelline membrane protein of the domesticated silkmoth Bombyx mori, is an essential component of the developing ovarian follicle

    Article • Insect Biochemistry and Molecular Biology, September 2012, Elsevier

    Professor Kostas Iatrou

  16. Bombyx mori DNA/RNA non-specific nuclease: Expression of isoforms in insect culture cells, subcellular localization and functional assays

    Article • Journal of Insect Physiology, August 2012, Elsevier

    Professor Kostas Iatrou

  17. Differential inhibition of BmRelish1-dependent transcription in lepidopteran cells by bracovirus ankyrin-repeat proteins

    Article • Insect Biochemistry and Molecular Biology, December 2011, Elsevier

    Professor Kostas Iatrou

  18. Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents

    Article • Cellular and Molecular Life Sciences, June 2011, Springer Science + Business Media

    Professor Kostas Iatrou

  19. RNA interference in Lepidoptera: An overview of successful and unsuccessful studies and implications for experimental design

    Article • Journal of Insect Physiology, February 2011, Elsevier

    Dr Ioannis Eleftherianos, Professor Kostas Iatrou, Dr Alexie Papanicolaou

  20. Expression and Membrane Topology of Anopheles gambiae Odorant Receptors in Lepidopteran Insect Cells

    Article • PLOS One, November 2010, PLOS

    Professor Kostas Iatrou

  21. Cooperative interactions between odorant-binding proteins of Anopheles gambiae

    Article • Cellular and Molecular Life Sciences, October 2010, Springer Science + Business Media

    Professor Kostas Iatrou

  22. Soluble forms of the cell adhesion molecule L1 produced by insect and baculovirus-transduced mammalian cells enhance Schwann cell motility

    Article • Journal of Neurochemistry, October 2010, Wiley

    Professor Kostas Iatrou

  23. Baculoviruses deficient in ie1 gene function abrogate viral gene expression in transduced mammalian cells

    Article • Virology, October 2010, Elsevier

    Professor Kostas Iatrou

  24. Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays

    Article • Pest Management Science, July 2010, Wiley

    Professor Kostas Iatrou

  25. The Anopheles gambiae Odorant Binding Protein 1 (AgamOBP1) Mediates Indole Recognition in the Antennae of Female Mosquitoes

    Article • PLOS One, March 2010, PLOS

    Professor Kostas Iatrou

  26. Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays

    Article • Pest Management Science, January 2010, Wiley

    Professor Kostas Iatrou

  27. Antennal expression pattern of two olfactory receptors and an odorant binding protein implicated in host odor detection by the malaria vector Anopheles gambiae

    Article • International Journal of Biological Sciences, January 2010, Ivyspring International Publisher

    Professor Kostas Iatrou

  28. BmCAP, a silkmoth gene encoding multiple protein isoforms characterized by SoHo and SH3 domains: Expression analysis during ovarian follicular development

    Article • Insect Biochemistry and Molecular Biology, December 2009, Elsevier

    Professor Kostas Iatrou

  29. Endoparasitoid wasp bracovirus-mediated inhibition of hemolin function and lepidopteran host immunosuppression

    Article • Cellular Microbiology, October 2008, Wiley

    Professor Kostas Iatrou

  30. Non-steroidal ecdysteroid agonist chromafenozide: Gene induction activity, cell proliferation inhibition and larvicidal activity

    Article • Pesticide Biochemistry and Physiology, October 2008, Elsevier

    Professor Kostas Iatrou

  31. Ecdysteroid signaling in ecdysteroid-resistant cell lines from the polyphagous noctuid pest Spodoptera exigua

    Article • Insect Biochemistry and Molecular Biology, September 2008, Elsevier

    Professor Kostas Iatrou

  32. Sex-biased expression of odorant receptors in antennae and palps of the African malaria vector Anopheles gambiae

    Article • Insect Biochemistry and Molecular Biology, February 2008, Elsevier

    Professor Kostas Iatrou

  33. Juvenile hormone analogs do not affect directly the activity of the ecdysteroid receptor complex in insect culture cell lines

    Article • Journal of Insect Physiology, February 2008, Elsevier

    Professor Kostas Iatrou

  34. Prostaglandin signaling and ovarian follicle development in the silkmoth, Bombyx mori

    Article • Insect Biochemistry and Molecular Biology, August 2007, Elsevier

    Professor Kostas Iatrou

  35. 7 th International Workshop on the Molecular Biology and Genetics of the Lepidoptera

    Article • Journal of Insect Science, May 2007, Oxford University Press (OUP)

    Professor Kostas Iatrou

  36. 16 th International Ecdysone Workshop: July 10–14, 2006, Ghent University, Belgium

    Article • Journal of Insect Science, March 2007, Oxford University Press (OUP)

    Professor Kostas Iatrou

  37. Specific interactions among odorant‐binding proteins of the African malaria vector Anopheles gambiae

    Article • Insect Molecular Biology, December 2006, Wiley

    Professor Kostas Iatrou

  38. Baculovirus-Mediated Gene Delivery into Mammalian Cells Does Not Alter Their Transcriptional and Differentiating Potential but Is Accompanied by Early Viral Gene Expression

    Article • Journal of Virology, April 2006, ASM Journals

    Professor Kostas Iatrou

  39. High-throughput screening of ecdysone agonists using a reporter gene assay followed by 3-D QSAR analysis of the molting hormonal activity

    Article • Bioorganic & Medicinal Chemistry, February 2006, Elsevier

    Professor Kostas Iatrou

  40. Stably Transformed Insect Cell Lines: Tools for Expression of Secreted and Membrane‐anchored Proteins and High‐throughput Screening Platforms for Drug and Insecticide Discovery

    Article • January 2006, Elsevier

    Professor Kostas Iatrou

  41. Transformed lepidopteran cells expressing a protein of the silkmoth fat body display enhanced susceptibility to baculovirus infection and produce high titers of budded virus in serum-free media

    Article • Journal of Biotechnology, November 2005, Elsevier

    Professor Kostas Iatrou

  42. A Virus Essential for Insect Host-Parasite Interactions Encodes Cystatins

    Article • Journal of Virology, August 2005, ASM Journals

    Professor Kostas Iatrou

  43. Expression of a Toxoneuron nigriceps polydnavirus-encoded protein causes apoptosis-like programmed cell death in lepidopteran insect cells

    Article • Journal of General Virology, April 2005, Society for General Microbiology

    Professor Kostas Iatrou

  44. Functional expression of mammalian opioid receptors in insect cells and high-throughput screening platforms for receptor ligand mimetics

    Article • Cellular and Molecular Life Sciences, April 2005, Springer Science + Business Media

    Professor Kostas Iatrou

  45. Introduction

    Article • January 2005, Elsevier

    Professor Kostas Iatrou

  46. Insect Cell Culture and Recombinant Protein Expression Systems

    Article • January 2005, Elsevier

    Professor Kostas Iatrou

  47. Vitellogenesis and Post-Vitellogenic Maturation of the Insect Ovarian Follicle

    Article • January 2005, Elsevier

    Professor Kostas Iatrou

  48. Transfected insect cells in suspension culture rapidly yield moderate quantities of recombinant proteins in protein-free culture medium

    Article • Protein Expression and Purification, August 2004, Elsevier

    Professor Kostas Iatrou

  49. The ecdysone regulatory cascade and ovarian development in lepidopteran insects: insights from the silkmoth paradigm

    Article • Insect Biochemistry and Molecular Biology, December 2003, Elsevier

    Professor Kostas Iatrou

  50. A cell‐based high‐throughput screening system for detecting ecdysteroid agonists and antagonists in plant extracts and libraries of synthetic compounds

    Article • The FASEB Journal, November 2003, Wiley

    Professor Kostas Iatrou

  51. The orphan nuclear receptors BmE75A and BmE75C of the silkmoth Bombyx mori: hornmonal control and ovarian expression

    Article • Insect Biochemistry and Molecular Biology, December 2002, Elsevier

    Professor Kostas Iatrou

  52. The BmE75 Nuclear Receptors Function as Dominant Repressors of the Nuclear Receptor BmHR3A

    Article • Journal of Biological Chemistry, November 2002, Elsevier

    Professor Kostas Iatrou

  53. An ovarian follicular epithelium protein of the silkworm (Bombyx mori) that associates with the vitelline membrane and contributes to the structural integrity of the follicle

    Article • FEBS Letters, July 2002, Wiley

    Professor Kostas Iatrou

  54. The orphan nuclear receptor BmHR3A of Bombyx mori: hormonal control, ovarian expression and functional properties

    Article • Mechanisms of Development, May 2001, Elsevier

    Professor Kostas Iatrou

  55. Secretion of cytoplasmic and nuclear proteins from animal cells using novel secretion modules

    Article • Proteins Structure Function and Bioinformatics, October 2000, Wiley

    Professor Kostas Iatrou

  56. Mariner (Mos1) transposase and genomic integration of foreign gene sequences in Bombyx mori cells

    Article • Insect Molecular Biology, April 2000, Wiley

    Professor Kostas Iatrou

  57. DETERMINANTS OF THE FUNCTIONAL INTERACTION BETWEEN THE SOLUBLE GM-CSF RECEPTOR AND THE GM-CSF RECEPTOR β-SUBUNIT

    Article • Cytokine, March 2000, Elsevier

    Professor Kostas Iatrou

  58. Secretion of cytoplasmic and nuclear proteins from animal cells using novel secretion modules

    Article • Proteins Structure Function and Bioinformatics, January 2000, Wiley

    Professor Kostas Iatrou

  59. Minimal Domain Requirement for Cation Transport by the Potassium-dependent Na/Ca-K Exchanger

    Article • Journal of Biological Chemistry, January 2000, Elsevier

    Professor Kostas Iatrou

  60. Use of Flow Cytometry to Rapidly Optimize the Transfection of Animal Cells

    Article • BioTechniques, January 2000, Taylor & Francis

    Professor Kostas Iatrou

  61. Screening of Transformed Insect Cell Lines for Recombinant Protein Production

    Article • Biotechnology Progress, December 1999, Wiley

    Professor Kostas Iatrou

  62. The ecdysone agonist tebufenozide (RH-5992) blocks the progression into the ecdysteroid-induced regulatory cascade and arrests silkmoth oogenesis at mid-vitellogenesis

    Article • Insect Biochemistry and Molecular Biology, November 1999, Elsevier

    Professor Kostas Iatrou

  63. Transformed lepidopteran insect cells: New sources of recombinant human tissue plasminogen activator

    Article • Biotechnology and Bioengineering, August 1999, Wiley

    Professor Kostas Iatrou

  64. Transformed lepidopteran insect cells: New sources of recombinant human tissue plasminogen activator

    Article • Biotechnology and Bioengineering, August 1999, Wiley

    Professor Kostas Iatrou

  65. High-level expression of secreted glycoproteins in transformed lepidopteran insect cells using a novel expression vector

    Article • Biotechnology and Bioengineering, December 1998, Wiley

    Professor Kostas Iatrou

  66. The p95 Gene of Bombyx mori Nuclear Polyhedrosis Virus: Temporal Expression and Functional Properties

    Article • Journal of Virology, June 1998, ASM Journals

    Professor Kostas Iatrou

  67. The orphan receptor BmHNF-4 of the silkmoth Bombyx mori: ovarian and zygotic expression of two mRNA isoforms encoding polypeptides with different activating domains

    Article • Mechanisms of Development, March 1998, Elsevier

    Professor Kostas Iatrou

  68. A Baculovirus (Bombyx mori Nuclear Polyhedrosis Virus) Repeat Element Functions as a Powerful Constitutive Enhancer in Transfected Insect Cells

    Article • Journal of Biological Chemistry, December 1997, Elsevier

    Professor Kostas Iatrou

  69. Characterization of a domain of the genome of BmNPV containing a functional gene for a small capsid protein and harboring deletions eliminating three open reading frames that are present in AcNPV

    Article • Gene, January 1997, Elsevier

    Professor Kostas Iatrou

  70. The genes encoding the P39 and CG30 proteins of Bombyx mori nuclear polyhedrosis virus

    Article • Journal of General Virology, December 1996, Society for General Microbiology

    Professor Kostas Iatrou

  71. Trans-Activation of a Cell Housekeeping Gene Promoter by the IE1 Gene Product of Baculoviruses

    Article • Virology, April 1996, Elsevier

    Professor Kostas Iatrou

  72. Bombyx EcR (BmEcR) and Bombyx USP (BmCF1) combine to form a functional ecdysone receptor

    Article • Insect Biochemistry and Molecular Biology, March 1996, Elsevier

    Professor Kostas Iatrou

  73. The silkmoth homolog of the Drosophila ecdysone receptor (BI Isoform): Cloning and analysis of expression during follicular cell differentiation

    Article • Insect Biochemistry and Molecular Biology, July 1995, Elsevier

    Professor Kostas Iatrou

  74. Development Regulation of a Silkworm Gene Encoding Multiple GATA-type Transcription Factors by Alternative Splicing

    Article • Journal of Molecular Biology, February 1995, Elsevier

    Professor Kostas Iatrou

  75. Optimum infection conditions for recombinant protein production in insect cell (Bm5) suspension culture

    Article • Biotechnology Progress, November 1994, Wiley

    Professor Kostas Iatrou

  76. Transfer vectors for maximal expression of passenger genes in theBombyx mori nuclear polyhedrosis virus expression system

    Article • Biotechnology and Bioengineering, December 1993, Wiley

    Professor Kostas Iatrou

  77. Silk moth chorion pseudogenes: Hallmarks of genomic evolution by sequence duplication and gene conversion

    Article • Journal of Molecular Evolution, August 1993, Springer Science + Business Media

    Professor Kostas Iatrou

  78. Baculovirus expression vectors: A laboratory manual

    Article • Cell, July 1993, Elsevier

    Professor Kostas Iatrou

  79. A two-stage bioreactor system for the production of recombinant proteins using a genetically engineered baculovirus/insect cell system

    Article • Biotechnology and Bioengineering, July 1993, Wiley

    Professor Kostas Iatrou

  80. Investigation of reduced serum and serum-free media for the cultivation of insect cells (Bm5) and the production of baculovirus (BmNPV)

    Article • Biotechnology and Bioengineering, December 1992, Wiley

    Professor Kostas Iatrou

  81. A cellular promoter-based expression cassette for generating recombinant baculoviruses directing rapid expression of passenger genes in infected insects

    Article • Virology, October 1992, Elsevier

    Professor Kostas Iatrou

  82. Early establishment and autonomous implementation of a developmental program controlling silkmoth chorion gene expression

    Article • Developmental Biology, March 1992, Elsevier

    Professor Kostas Iatrou

  83. Kinetic data for the BM‐5 insect cell line in repeated‐batch suspension cultures

    Article • Biotechnology and Bioengineering, June 1991, Wiley

    Professor Kostas Iatrou

  84. Developmental regulation of covalent modification of double-stranded RNA during silkmoth oogenesis

    Article • Journal of Molecular Biology, April 1991, Elsevier

    Professor Kostas Iatrou

  85. Synergistic interactions of silkmoth chorion promoter-binding factors.

    Article • Molecular and Cellular Biology, April 1991, ASM Journals

    Professor Kostas Iatrou

  86. Growth characteristics of aBombyx moriinsect cell line in stationary and suspension cultures

    Article • The Canadian Journal of Chemical Engineering, April 1991, Wiley

    Professor Kostas Iatrou

  87. Silkmoth chorion antisense RNA

    Article • Journal of Molecular Biology, May 1990, Elsevier

    Professor Kostas Iatrou

  88. Tissue-specific expression of silkmoth chorion genes in vivo using Bombyx mori nuclear polyhedrosis virus as a transducing vector.

    Article • Proceedings of the National Academy of Sciences, May 1990, Proceedings of the National Academy of Sciences

    Professor Kostas Iatrou

  89. Recombinant baculoviruses as vectors for identifying proteins encoded by intron-containing members of complex multigene families.

    Article • Proceedings of the National Academy of Sciences, December 1989, Proceedings of the National Academy of Sciences

    Professor Kostas Iatrou

  90. Chorion antisense RNA during oogenesis in

    Article • Cell Differentiation and Development, August 1989, Elsevier

    Professor Kostas Iatrou

  91. GrB deletion of the chorion locus of the silkmoth Bombyx mori

    Article • Journal of Molecular Biology, February 1989, Elsevier

    Professor Kostas Iatrou

  92. Bombyx mori nuclear polyhedrosis virus-based vectors for expressing passenger genes in silkmoth cells under viral or cellular promoter control

    Article • Gene, January 1989, Elsevier

    Professor Kostas Iatrou

  93. Identification of a transcriptionally active pseudogene in the chorion locus of the silkmoth Bombyx mori

    Article • Journal of Molecular Biology, October 1988, Elsevier

    Professor Kostas Iatrou

  94. Infection of silkmoth follicular cells with Bombyx mori nuclear polyhedrosis virus

    Article • Journal of Invertebrate Pathology, July 1986, Elsevier

    Professor Kostas Iatrou

  95. Polyhedrin gene of Bombyx mori nuclear polyhedrosis virus

    Article • Journal of Virology, May 1985, ASM Journals

    Professor Kostas Iatrou

  96. DNA sequence transfer between two high-cysteine chorion gene families in the silkmoth Bombyx mori.

    Article • Proceedings of the National Academy of Sciences, July 1984, Proceedings of the National Academy of Sciences

    Professor Kostas Iatrou

  97. Structural features of B family chorion sequences in the silkmoth Bombyx mori, and their evolutionary implications.

    Article • The EMBO Journal, October 1983, Springer Science + Business Media

    Professor Kostas Iatrou

  98. Developmental classes and homologous families of chorion genes in Bombyx mori

    Article • Journal of Molecular Biology, May 1982, Elsevier

    Professor Kostas Iatrou

  99. Molecular analysis of the protamine multi-gene family in rainbow trout testis

    Article • Nucleic Acids Research, January 1981, Oxford University Press (OUP)

    Professor Kostas Iatrou

  100. Molecular analysis of the GrB mutation in Bombyx mori through the use of a chorion cDNA library

    Article • Cell, July 1980, Elsevier

    Professor Kostas Iatrou

  101. Protamine messenger RNA: partial purification and characterization of a heterogeneous family of polyadenylated messenger components

    Article • Canadian Journal of Biochemistry, June 1979, Canadian Science Publishing

    Professor Kostas Iatrou

  102. Translation of partially purified poly(A)+ protamine messenger RNA components in wheat germ and rabbit reticulocyte cell-free systems Evidence for translational control mechanisms

    Article • Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, May 1979, Elsevier

    Professor Kostas Iatrou

  103. A simple procedure for the isolation and purification of protamine messenger ribonucleic acid from trout testis

    Article • Biochemical Journal, June 1978, Portland Press Ltd.

    Professor Kostas Iatrou

  104. Protamine messenger RNA: Evidence for early synthesis and accumulation during spermatogenesis in rainbow trout

    Article • Developmental Biology, May 1978, Elsevier

    Professor Kostas Iatrou

  105. Isolation and characterization of trout testis protamine mRNAs lacking Poly(A)

    Article • Cell, March 1977, Elsevier

    Professor Kostas Iatrou

  106. The distribution of poly(A)+ and poly(A)− protamine messenger RNA sequences in the developing trout testis

    Article • Cell, March 1977, Elsevier

    Professor Kostas Iatrou

  107. The Structure and Function of Protamine mRNA from Developing Trout Testis

    Article • January 1977, Elsevier

    Professor Kostas Iatrou

  108. Ecdysteroids and Ecdysteroid Signaling Pathways During Insect Oogenesis

    Article • Springer Science + Business Media

    Professor Kostas Iatrou

  109. Applications of RNA Interference in Ecdysone Research

    Article • Springer Science + Business Media

    Professor Kostas Iatrou

  110. Engineered baculoviruses: molecular tools for lepidopteran developmental biology and physiology and potential agents for insect pest control

    Article • Cambridge University Press

    Professor Kostas Iatrou