All Stories

  1. Deep Learning-Driven Estimation of Centiloid Scales from Amyloid PET Images with 11C-PiB and 18F-Labeled Tracers in Alzheimer’s Disease

    Article • Brain Sciences, April 2024, MDPI AG

    Dr. Koki Hasegawa

  2. Characterization of the expression of gastrin‐releasing peptide and its receptor in the trigeminal and spinal somatosensory systems of Japanese macaque monkeys: Insight into humans

    Article • The Journal of Comparative Neurology, June 2022, Wiley

    Dr. Koki Hasegawa

  3. Development of a phoswich detector composed of ZnS(Ag) and YAP(Ce) for astatine-211 imaging

    Article • Radiation Measurements, April 2022, Elsevier

    Dr. Koki Hasegawa

  4. Corrigendum: Kiss1R Identification and Biodistribution Analysis Employing a Western Ligand Blot and Ligand‐Derivative Stain with a FITC‐Kisspeptin Derivative

    Article • ChemMedChem, January 2021, Wiley

    Dr. Koki Hasegawa

  5. Facile synthesis of 2‐deoxy‐2‐[18F]fluorosorbitol using sodium borohydride on aluminum oxide

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, October 2020, Wiley

    Dr. Koki Hasegawa

  6. Rationale for Translational Research on Targeted Alpha Therapy in Japan —Renaissance of Radiopharmaceuticals Utilizing Astatine-211 and Actinium-225—

    Article • RADIOISOTOPES, October 2020, Japan Radioisotope Association

    Dr. Koki Hasegawa

  7. Enhancement of direct membrane penetration of arginine-rich peptides by polyproline II helix structure

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, October 2020, Elsevier

    Dr. Koki Hasegawa

  8. Kiss1R Identification and Biodistribution Analysis Employing a Western Ligand Blot and Ligand‐Derivative Stain with a FITC‐Kisspeptin Derivative

    Article • ChemMedChem, August 2020, Wiley

    Dr. Koki Hasegawa

  9. A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding region of human apolipoprotein E

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2019, Elsevier

    Dr. Koki Hasegawa

  10. Relationship between the fluorescence intensity of rhodamine-labeled orexin A and the calcium responses in cortical neurons: An in vivo two-photon calcium imaging study

    Article • Journal of Pharmacological Sciences, September 2018, Elsevier

    Dr. Koki Hasegawa

  11. Expression of Draxin in Lung Carcinomas

    Article • ACTA HISTOCHEMICA ET CYTOCHEMICA, January 2018, Japan Society of Histochemistry & Cytochemistry

    Dr. Koki Hasegawa

  12. Somatostatin receptor staining in FFPE sections using a ligand derivative dye as an alternative to immunostaining

    Article • PLOS One, February 2017, PLOS

    Dr. Koki Hasegawa

  13. Improved68Ga-labeling method using ethanol addition: Application to the α-helical peptide DOTA-FAMP

    Article • Journal of Labelled Compounds, December 2016, Wiley

    Dr. Koki Hasegawa

  14. Visualization and Quantitative Assessment of the Brain Distribution of Insulin through Nose-to-Brain Delivery Based on the Cell-Penetrating Peptide Noncovalent Strategy

    Article • Molecular Pharmaceutics, February 2016, American Chemical Society (ACS)

    Dr. Koki Hasegawa

  15. Hybrid Light Imaging Using Cerenkov Luminescence and Liquid Scintillation for Preclinical Optical Imaging In Vivo

    Article • Molecular Imaging and Biology, January 2016, Springer Science + Business Media

    Dr. Koki Hasegawa

  16. Insulinoma-Associated Protein 1 Is a Crucial Regulator of Neuroendocrine Differentiation in Lung Cancer

    Article • American Journal Of Pathology, December 2015, Elsevier

    Dr. Koki Hasegawa

  17. Iodine-131 imaging using 284 keV photons with a small animal CZT-SPECT system dedicated to low-medium-energy photon detection

    Article • Annals of Nuclear Medicine, September 2015, Springer Science + Business Media

    Dr. Koki Hasegawa

  18. N otch1 controls cell chemoresistance in small cell lung carcinoma cells

    Article • Thoracic Cancer, July 2015, Wiley

    Dr. Koki Hasegawa

  19. Notch1 controls cell invasion and metastasis in small cell lung carcinoma cell lines

    Article • Lung Cancer, December 2014, Elsevier

    Dr. Koki Hasegawa

  20. Notch1 signaling controls cell proliferation, apoptosis and differentiation in lung carcinoma

    Article • Lung Cancer, August 2014, Elsevier

    Dr. Koki Hasegawa

  21. Identification of nuclear phosphoproteins as novel tobacco markers in mouse lung tissue following short-term exposure to tobacco smoke

    Article • FEBS Open Bio, January 2014, Wiley

    Dr. Koki Hasegawa

  22. Positron emission tomography study on pancreatic somatostatin receptors in normal and diabetic rats with 68Ga-DOTA-octreotide: A potential PET tracer for beta cell mass measurement

    Article • Biochemical and Biophysical Research Communications, December 2013, Elsevier

    Dr. Koki Hasegawa

  23. 64Cu-DOTA-Trastuzumab PET Imaging in Patients with HER2-Positive Breast Cancer

    Article • Journal of Nuclear Medicine, September 2013, Society of Nuclear Medicine

    Dr. Koki Hasegawa

  24. Detection of early stage atherosclerotic plaques using PET and CT fusion imaging targeting P-selectin in low density lipoprotein receptor-deficient mice

    Article • Biochemical and Biophysical Research Communications, March 2013, Elsevier

    Dr. Koki Hasegawa

  25. Novel Molecular Imaging of Atherosclerosis With Gallium-68-Labeled Apolipoprotein A-I Mimetic Peptide and Positron Emission Tomography

    Article • Circulation Journal, January 2013, Japanese Circulation Society

    Dr. Koki Hasegawa

  26. Noninvasive Imaging of Dendrimer-Type N-Glycan Clusters: In Vivo Dynamics Dependence on Oligosaccharide Structure

    Article • Angewandte Chemie, September 2010, Wiley

    Professor Koichi Fukase, Dr. Koki Hasegawa

  27. Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography

    Article • Journal of Controlled Release, August 2010, Elsevier

    Dr. Koki Hasegawa

  28. A Submicrogram-Scale Protocol for Biomolecule-Based PET Imaging by Rapid 6π-Azaelectrocyclization: Visualization of Sialic Acid Dependent Circulatory Residence of Glycoproteins

    Article • Angewandte Chemie, January 2008, Wiley

    Professor Koichi Fukase, Dr. Koki Hasegawa

  29. Recent Progress Using the Thioester Method

    Article • ChemInform, June 2007, Wiley

    Dr. Koki Hasegawa

  30. Synthesis of an olefin-containing cyclic peptide using the solid-phase Horner–Emmons reaction

    Article • Tetrahedron Letters, January 2004, Elsevier

    Dr. Koki Hasegawa

  31. Article • International Journal of Peptide Research and Therapeutics, January 2001, Springer Science + Business Media

    Dr. Koki Hasegawa

  32. Polypeptide synthesis using an expressed peptide as a building block for condensation with a peptide thioester: Application to the synthesis of phosphorylated p21Max protein(1-101)

    Article • Journal of Peptide Science, January 2001, Wiley

    Dr. Koki Hasegawa

  33. Polypeptide synthesis using an expressed peptide as a building block via the thioester method

    Article • Tetrahedron Letters, April 2000, Elsevier

    Dr. Koki Hasegawa

  34. Synthesis of a Phosphorylated Polypeptide by a Thioester Method

    Article • Bulletin of the Chemical Society of Japan, January 2000, The Chemical Society of Japan

    Dr. Koki Hasegawa

  35. Synthesis of phosphorylated polypeptide by a thioester method

    Article • Springer Science + Business Media

    Dr. Koki Hasegawa

  36. Synthesis of phosphorylated CRE BP1(19-106) amide using a phosphopeptide thioester prepared directly by an Fmoc solid-phase method

    Article • Springer Science + Business Media

    Dr. Koki Hasegawa