All Stories

  1. Dynamic and functional changes in vascular endothelial cell monolayers under combined hypoxic and inflammatory stimuli

    Article • Scientific Reports, December 2025, Springer Science + Business Media

    Prof. Kenichi Funamoto

  2. Dictyostelium discoideum chemotaxis is altered by hypoxia to orient streaming toward higher oxygen levels

    Article • BMC Molecular and Cell Biology, November 2025, Springer Science + Business Media

    Prof. Kenichi Funamoto

  3. Dictyostelium discoideum chemotaxis is altered by hypoxia to orient streaming toward higher oxygen level independently of aerotaxis

    Article • August 2025, Cold Spring Harbor Laboratory Press

    Prof. Kenichi Funamoto

  4. Observation of Collective Migration of Vascular Endothelial Cells Exposed to Lipopolysaccharide and Hypoxia

    Article • July 2025, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  5. Proliferation and weak aerotaxis changes the cancer cell distribution in oxygen gradients at physiological level

    Article • Microfluidics and Nanofluidics, March 2025, Springer Science + Business Media

    Prof. Kenichi Funamoto

  6. Cell-cultured PDMS vascular model to allow placement of implant devices

    Article • January 2025, Cold Spring Harbor Laboratory Press

    Prof. Kenichi Funamoto

  7. Evaluation of Effects of Cyclic Hypoxia on Vascular Permeability Using Microfluidic Device

    Article • December 2024, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  8. Aneurysm Wall Enhancement Can Predict Rupture Point in Intracranial Aneurysms With Multiple Blebs

    Article • Neurosurgery, August 2024, Wolters Kluwer Health

    Prof. Kenichi Funamoto

  9. Hypoxia suppresses glucose-induced increases in collective cell migration in vascular endothelial cell monolayers

    Article • Scientific Reports, March 2024, Springer Science + Business Media

    Prof. Kenichi Funamoto

  10. Biological characterization of breast cancer spheroid formed by fast fabrication method

    Article • In vitro models, February 2024, Springer Science + Business Media

    Prof. Kenichi Funamoto

  11. Behavior of breast cancer cells under oxygen concentration gradients in a microfluidic device

    Article • July 2023, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  12. Evaluation of the effects of glucose and oxygen on the vascular endothelial cell migration

    Article • July 2023, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  13. Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans

    Article • Nature Biomedical Engineering, July 2023, Springer Science + Business Media

    Prof. Kenichi Funamoto

  14. The aerotaxis of Dictyostelium discoideum is independent of mitochondria, nitric oxide and oxidative stress

    Article • Frontiers in Cell and Developmental Biology, June 2023, Frontiers

    Prof. Kenichi Funamoto

  15. Microfluidic platform for the reproduction of hypoxic vascular microenvironments

    Article • Scientific Reports, April 2023, Springer Science + Business Media

    Prof. Kenichi Funamoto

  16. Numerical analysis of hemodynamic changes and blood stagnation in the left ventricle by internal structures and torsional motion

    Article • AIP Advances, April 2023, American Institute of Physics

    Prof. Kenichi Funamoto

  17. Stiffness of primordial germ cells is required for their extravasation in avian embryos

    Article • iScience, December 2022, Elsevier

    Prof. Kenichi Funamoto

  18. A Review of Functional Analysis of Endothelial Cells in Flow Chambers

    Article • Journal of Functional Biomaterials, July 2022, MDPI AG

    Prof. Kenichi Funamoto

  19. Model-based estimation of QT intervals of mouse fetal electrocardiogram

    Article • BioMedical Engineering OnLine, June 2022, Springer Science + Business Media

    Prof. Kenichi Funamoto

  20. Stiffness of primordial germ cells is required for their extravasation in avian embryos

    Article • May 2022, Cold Spring Harbor Laboratory Press

    Prof. Kenichi Funamoto

  21. The Oxygen Gradient in Hypoxic Conditions Enhances and Guides Dictyostelium discoideum Migration

    Article • Processes, February 2022, MDPI AG

    Prof. Kenichi Funamoto

  22. Aerotaxis and aerokinesis of Dictyostelium discoideum under hypoxic microenvironments

    Article • November 2021, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  23. Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Article • eLife, August 2021, eLife

    Prof. Kenichi Funamoto

  24. Surface biofunctionalization with liquid-phase plasma treatment of collagen molecules

    Article • August 2021, Research Square

    Prof. Kenichi Funamoto

  25. Surface biofunctionalization with liquid-phase plasma treatment of collagen molecules

    Article • July 2021, Research Square

    Prof. Kenichi Funamoto

  26. P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers

    Article • Cell Adhesion & Migration, January 2021, Taylor & Francis

    Prof. Kenichi Funamoto

  27. Antihypertensive effect of brain-targeted mechanical intervention with passive head motion

    Article • September 2020, Cold Spring Harbor Laboratory Press

    Prof. Kenichi Funamoto

  28. Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Prof. Kenichi Funamoto

  29. Cancer cell migration and cancer drug screening in oxygen tension gradient chip

    Article • Biomicrofluidics, July 2020, American Institute of Physics

    Prof. Kenichi Funamoto

  30. Hydrostatic pressure promotes endothelial tube formation through aquaporin 1 and Ras-ERK signaling

    Article • Communications Biology, April 2020, Springer Science + Business Media

    Prof. Kenichi Funamoto

  31. Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension

    Article • APL Bioengineering, March 2020, American Institute of Physics

    Prof. Kenichi Funamoto

  32. Viscosity Estimation of a Suspension with Rigid Spheres in Circular Microchannels Using Particle Tracking Velocimetry

    Article • Micromachines, October 2019, MDPI AG

    Prof. Kenichi Funamoto

  33. Numerical analysis of the blood flow in the left ventricle with internal structures: Effect of trabeculae carneae models and atrial fibrillation

    Article • AIP Advances, October 2019, American Institute of Physics

    Toshiyuki Hayase, Prof. Kenichi Funamoto

  34. Experimental Study on the Effects of Radial Dispersion of Spherical Particles on the Suspension Rheology

    Article • July 2019, ASME International

    Prof. Kenichi Funamoto

  35. Oxygen-dependent contraction and degradation of the extracellular matrix mediated by interaction between tumor and endothelial cells

    Article • AIP Advances, April 2019, American Institute of Physics

    Prof. Kenichi Funamoto

  36. Migration of vascular endothelial cells in monolayers under hypoxic exposure

    Article • Integrative Biology, January 2019, Oxford University Press (OUP)

    Prof. Kenichi Funamoto

  37. Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images

    Article • Journal of Biomechanical Science and Engineering, January 2018, Japan Society of Mechanical Engineers

    Prof. Kenichi Funamoto

  38. Ultrasound Imaging of Mouse Fetal Intracranial Hemorrhage Due to Ischemia/Reperfusion

    Article • Frontiers in Physiology, May 2017, Frontiers

    Prof. Kenichi Funamoto

  39. Endothelial monolayer permeability under controlled oxygen tension

    Article • Integrative Biology, January 2017, Oxford University Press (OUP)

    Prof. Kenichi Funamoto

  40. Effects of upstream bifurcation and bend on the blood flow in a cerebral aneurysm

    Article • Journal of Biomechanical Science and Engineering, January 2017, Japan Society of Mechanical Engineers

    Prof. Kenichi Funamoto

  41. Daughter Sac Formation Related to Blood Inflow Jet in an Intracranial Aneurysm

    Article • World Neurosurgery, December 2016, Elsevier

    Dr. Shin-ichiro Sugiyama, Sherif Rashad, Prof. Kenichi Funamoto

  42. Deformation of Stenotic Blood Vessel Model Made From Poly (Vinyl Alcohol) Hydrogel by Hydrostatic Pressure

    Article • November 2016, ASME International

    Prof. Kenichi Funamoto

  43. Computational investigation toward selective collection of water particles containing odorous molecules by electrostatic spraying

    Article • Journal of Electrostatics, October 2016, Elsevier

    Prof. Kenichi Funamoto

  44. Photoplethysmography and ultrasonic-measurement-integrated simulation to clarify the relation between two-dimensional unsteady blood flow field and forward and backward waves in a carotid artery

    Article • Medical & Biological Engineering & Computing, July 2016, Springer Science + Business Media

    Prof. Kenichi Funamoto

  45. Reduced Uterine Perfusion Pressure (RUPP) Model of Preeclampsia in Mice

    Article • PLOS One, May 2016, PLOS

    Prof. Kenichi Funamoto

  46. strategies of glioma

    Article • Journal of Neurosurgery Spine, February 2016, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr. Shin-ichiro Sugiyama, rong zhang, Prof. Kenichi Funamoto

  47. Study of Estimation Method for Unsteady Inflow Velocity in Two-Dimensional Ultrasonic-Measurement-Integrated Blood Flow Simulation

    Article • IEEE Transactions on Biomedical Engineering, February 2016, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  48. Computational Hemodynamic Analysis for the Diagnosis of Atherosclerotic Changes in Intracranial Aneurysms: A Proof-of-Concept Study Using 3 Cases Harboring Atherosclerotic and Nonatherosclerotic Aneurysms Simultaneously

    Article • Computational and Mathematical Methods in Medicine, January 2016, Hindawi Publishing Corporation

    Dr. Shin-ichiro Sugiyama, Prof. Kenichi Funamoto

  49. Effects of inflow velocity profile on two-dimensional hemodynamic analysis by ordinary and ultrasonic-measurement-integrated simulations

    Article • Medical & Biological Engineering & Computing, August 2015, Springer Science + Business Media

    Prof. Kenichi Funamoto

  50. Numerical analysis of hemodynamic changes in the left atrium due to atrial fibrillation

    Article • Journal of Biomechanics, February 2015, Elsevier

    Prof. Kenichi Funamoto

  51. Investigation of characteristic hemodynamic parameters indicating thinning and thickening sites of cerebral aneurysms

    Article • Journal of Biomechanical Science and Engineering, January 2015, Japan Society of Mechanical Engineers

    Dr. Shin-ichiro Sugiyama, Prof. Kenichi Funamoto

  52. Blood flow analysis in carotid artery bifurcation by two-dimensional ultrasonic-measurement-integrated simulation

    Article • Journal of Biomechanical Science and Engineering, January 2015, Japan Society of Mechanical Engineers

    Prof. Kenichi Funamoto

  53. Numerical Analysis for Elucidation of Nonlinear Frictional Characteristics of a Deformed Erythrocyte Moving on a Plate in Medium Subject to Inclined Centrifugal Force

    Article • Journal of Biomechanical Engineering, October 2014, ASME International

    Prof. Kenichi Funamoto

  54. Development and feasibility study of a two-dimensional ultrasonic-measurement-integrated blood flow analysis system for hemodynamics in carotid arteries

    Article • Medical & Biological Engineering & Computing, September 2014, Springer Science + Business Media

    Prof. Kenichi Funamoto

  55. Microscopic observation of glass bead movement in soft tissue-mimicking phantom under ultrasound PW mode scanning

    Article • Journal of Medical Ultrasonics, August 2014, Springer Science + Business Media

    Prof. Kenichi Funamoto

  56. Poly(vinyl alcohol) gel ultrasound phantom with durability and visibility of internal flow

    Article • Journal of Medical Ultrasonics, August 2014, Springer Science + Business Media

    Prof. Kenichi Funamoto

  57. “Sonocytometry” — Novel diagnostic method of ultrasonic differentiation of cells in blood flow

    Article • August 2014, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  58. Hemodynamic Analysis of Intracranial Aneurysms with Atherosclerosis

    Article • January 2014, Springer Science + Business Media

    Prof. Kenichi Funamoto

  59. Computational simulation of convection-enhanced drug delivery in the non-human primate brainstem: a simple model predicting the drug distribution

    Article • Neurological Research, October 2013, Taylor & Francis

    Dr. Shin-ichiro Sugiyama, Prof. Kenichi Funamoto

  60. Fundamental study on micro calcification detection using twinkling sign (TS): The effect of stiffness of surrounding tissue on the appearance of TS

    Article • July 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  61. Simultaneous analysis system for blood pressure and flow using photoplethysmography and ultrasonic-measurement-integrated simulation

    Article • July 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  62. In vitro study of ultrasound radiation force-driven twinkling sign using PVA-H gel and glass beads tissue-mimicking phantom

    Article • Journal of Medical Ultrasonics, February 2013, Springer Science + Business Media

    Prof. Kenichi Funamoto

  63. Influence of Plaque Stiffness on Change of Blood Vessel Geometry Leading Hemodynamical Changes in PVA-H Stenosis Models

    Article • November 2012, ASME International

    Prof. Kenichi Funamoto

  64. Reproduction of pressure field in ultrasonic-measurement-integrated simulation of blood flow

    Article • International Journal for Numerical Methods in Biomedical Engineering, November 2012, Wiley

    Prof. Kenichi Funamoto

  65. Hemodynamic Analysis of Growing Intracranial Aneurysms Arising from a Posterior Inferior Cerebellar Artery

    Article • World Neurosurgery, November 2012, Elsevier

    Dr. Shin-ichiro Sugiyama, Prof. Kenichi Funamoto

  66. Erratum to “Influence of surface model extraction parameter on computational fluid dynamics modeling of cerebral aneurysms” [Journal of Biomechanics 45 (2012) 2355–2361]

    Article • Journal of Biomechanics, November 2012, Elsevier

    Dr. Shin-ichiro Sugiyama, Prof. Kenichi Funamoto

  67. Influence of surface model extraction parameter on computational fluid dynamics modeling of cerebral aneurysms

    Article • Journal of Biomechanics, September 2012, Elsevier

    Dr. Shin-ichiro Sugiyama, Prof. Kenichi Funamoto

  68. A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment

    Article • Lab on a Chip, January 2012, Royal Society of Chemistry

    Prof. Kenichi Funamoto

  69. Local Hemodynamics at the Rupture Point of Cerebral Aneurysms Determined by Computational Fluid Dynamics Analysis

    Article • Cerebrovascular Diseases, January 2012, Karger Publishers

    Dr. Shin-ichiro Sugiyama, Prof. Kenichi Funamoto

  70. Erratum to: Implementation of visual data mining for unsteady blood flow field in an aortic aneurysm

    Article • Journal of Visualization, November 2011, Springer Science + Business Media

    Prof. Kenichi Funamoto

  71. Volumetric and Angiogenic Evaluation of Antitumor Effects with Acoustic Liposome and High-Frequency Ultrasound

    Article • Cancer Research, October 2011, American Association for Cancer Research (AACR)

    Prof. Kenichi Funamoto

  72. Implementation of visual data mining for unsteady blood flow field in an aortic aneurysm

    Article • Journal of Visualization, August 2011, Springer Science + Business Media

    Prof. Kenichi Funamoto

  73. Hemodynamic Changes in the Left Atrium due to Atrial Fibrillation

    Article • June 2011, ASME International

    Prof. Kenichi Funamoto

  74. Numerical Analysis of Effects of Measurement Errors on Ultrasonic-Measurement-Integrated Simulation

    Article • IEEE Transactions on Biomedical Engineering, March 2011, Institute of Electrical & Electronics Engineers (IEEE)

    Prof. Kenichi Funamoto

  75. Visualization of Microcirculation Based on Brightness Variation in Contrast-Enhanced Ultrasound

    Article • June 2010, ASME International

    Prof. Kenichi Funamoto

  76. Effect of Measurement Error on Ultrasonic-Measurement-Integrated Simulation of Blood Flow in an Aortic Aneurysm

    Article • January 2010, Springer Science + Business Media

    Prof. Kenichi Funamoto

  77. Reproduction of Blood Flow Field by Numerical Simulation Integrated With Ultrasonic Measurement With Noise

    Article • June 2009, ASME International

    Prof. Kenichi Funamoto

  78. Numerical Validation of MR-Measurement-Integrated Simulation of Blood Flow in a Cerebral Aneurysm

    Article • Annals of Biomedical Engineering, April 2009, Springer Science + Business Media

    Prof. Kenichi Funamoto

  79. Numerical Experiment of Transient and Steady Characteristics of Ultrasonic-Measurement-Integrated Simulation in Three-Dimensional Blood Flow Analysis

    Article • Annals of Biomedical Engineering, November 2008, Springer Science + Business Media

    Prof. Kenichi Funamoto

  80. Frictional Characteristics of Erythrocytes on Coated Glass Plates Subject to Inclined Centrifugal Forces

    Article • Journal of Biomechanical Engineering, July 2008, ASME International

    Prof. Kenichi Funamoto

  81. Numerical Experiment for Ultrasonic-Measurement-Integrated Simulation of Three-Dimensional Unsteady Blood Flow

    Article • Annals of Biomedical Engineering, May 2008, Springer Science + Business Media

    Prof. Kenichi Funamoto

  82. Numerical Experiment for Ultrasonic-Measurement-Integrated Simulation of Developed Laminar Pipe Flow Using Axisymmetric Model

    Article • Journal of Biomechanical Science and Engineering, January 2008, Japan Society of Mechanical Engineers

    Prof. Kenichi Funamoto

  83. Accuracy of Ultrasonic-Measurement-Integrated Simulation for Three-Dimensional Blood Flow in Aneurysmal Aorta

    Article • January 2007, ASME International

    Prof. Kenichi Funamoto

  84. Numerical Study on Variation of Feedback Methods in Ultrasonic-Measurement-Integrated Simulation of Blood Flow in the Aneurysmal Aorta

    Article • JSME International Journal Series C, January 2006, Japan Society of Mechanical Engineers

    Prof. Kenichi Funamoto

  85. Fundamental Study of Ultrasonic-Measurement-Integrated Simulation of Real Blood Flow in the Aorta

    Article • Annals of Biomedical Engineering, April 2005, Springer Science + Business Media

    Prof. Kenichi Funamoto

  86. Numerical Evaluation of MR-Measurement-Integrated Simulation of Unsteady Hemodynamics in a Cerebral Aneurysm

    Article • Springer Science + Business Media

    Prof. Kenichi Funamoto