All Stories

  1. A legacy written in blood: maternal obesity, fetal programming, and the search for molecular interventions
  2. Renal hypertrophy and hyperfiltration is enhanced in early acquired compared with a congenital solitary function kidney model in sheep
  3. Special Issue “Sympathetic Nerves and Cardiovascular Diseases”
  4. The kidney in health and disease in 2022: Gaps in and opportunities for new knowledge
  5. Progress towards improving blood pressure control
  6. Novel AT2R agonist, β-Pro7Ang III, is cardio- and vaso-protective in diabetic spontaneously hypertensive rats
  7. Sympathetic Nervous System and Atherosclerosis
  8. Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney
  9. Antihypertensives and Antibiotics: Impact on Intestinal Dysfunction and Hypertension
  10. Sex- and age-related differences in renal and cardiac injury and senescence in stroke-prone spontaneously hypertensive rats
  11. Beneficial effects of brief early life angiotensin-converting enzyme inhibition wane with time in sheep with solitary functioning kidney
  12. Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice
  13. Extracting Information From Sympathetic Nerve Traffic in Gestational Hypertension
  14. AW-APSH-1: TARGETING WINDOWS OF PLASTICITY TO PREVENT HYPERTENSION.
  15. The Novel AT2 Receptor Agonist β-Pro7-AngIII Exerts Cardiac and Renal Anti-Fibrotic and Anti-Inflammatory Effects in High Salt-Fed Mice
  16. Bezlotoxumab prevents extraintestinal organ damage induced by Clostridioides difficile infection
  17. Strategies for immortalisation of amnion‐derived mesenchymal and epithelial cells
  18. Kidney Angiotensin in Cardiovascular Disease: Formation and Drug Targeting
  19. Brief Early Life Angiotensin-Converting Enzyme Inhibition Offers Renoprotection in Sheep with a Solitary Functioning Kidney at 8 Months of Age
  20. Renal Denervation in Combination With Angiotensin Receptor Blockade Prolongs Blood Pressure Trough During Hemorrhage
  21. Renal Deafferentation Prevents Progression of Hypertension and Changes to Sympathetic Reflexes in a Rabbit Model of Chronic Kidney Disease
  22. Relaxin Attenuates Organ Fibrosis via an Angiotensin Type 2 Receptor Mechanism in Aged Hypertensive Female Rats
  23. Blunted natriuretic response to saline loading in sheep with hypertensive kidney disease following radiofrequency catheter-based renal denervation
  24. In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism
  25. Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations
  26. Increase in Bioavailability of Nitric Oxide After Renal Denervation Improves Kidney Function in Sheep With Hypertensive Kidney Disease
  27. Considering Sex as a Biological Variable in Basic and Clinical Studies: An Endocrine Society Scientific Statement
  28. Connecting Generations of Scientists in the Council on Hypertension Through Harriet Dustan
  29. GPCRs (G-Protein–Coupled Receptors) as Microprocessors
  30. Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy
  31. Contribution of the Renal Nerves to Hypertension in a Rabbit Model of Chronic Kidney Disease
  32. Differential sympathetic response to lesion-induced chronic kidney disease in rabbits
  33. Physiology and Pathophysiology of Compensatory Adaptations of a Solitary Functioning Kidney
  34. The anti‐fibrotic actions of relaxin are mediated through AT2R‐associated protein phosphatases via RXFP1‐AT2R functional crosstalk in human cardiac myofibroblasts
  35. Renal functional effects of the highly selective AT2R agonist, β-Pro7 Ang III, in normotensive rats
  36. Serelaxin and the AT2 Receptor Agonist CGP42112 Evoked a Similar, Nonadditive, Cardiac Antifibrotic Effect in High Salt-Fed Mice That Were Refractory to Candesartan Cilexetil
  37. Fetal growth and well‐being in a study of maternal hypertension in rabbits
  38. “The more I learn, the more I realize how much I don’t know.” - The role of the renal nerves in hypertension
  39. mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans
  40. AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis
  41. Renal Denervation Update From the International Sympathetic Nervous System Summit
  42. Chronic low alcohol intake during pregnancy programs sex-specific cardiovascular deficits in rats
  43. Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation
  44. Sex Differences in the Role of the Angiotensin Type 2 Receptor in the Regulation of Blood Pressure
  45. Renal Denervation
  46. Adenosine Receptors
  47. Role of the Sympathetic Nervous System and Its Modulation in Renal Hypertension
  48. Sex-specific differences in hypertension and associated cardiovascular disease
  49. Perinatal Programming of Arterial Pressure
  50. Relaxin contributes to the regulation of arterial pressure in adult female mice
  51. New insights on glomerular hyperfiltration: a Japanese autopsy study
  52. Anti-fibrotic Potential of AT2 Receptor Agonists
  53. Editorial: Function of Renal Sympathetic Nerves
  54. Renal Denervation Promotes Atherosclerosis in Hypertensive Apolipoprotein E-Deficient Mice Infused with Angiotensin II
  55. Effect of renal denervation on kidney function in patients with chronic kidney disease
  56. Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage
  57. Perinatal Programming of Arterial Pressure
  58. Sex- and age-related differences in arterial pressure and albuminuria in mice
  59. Transcutaneous assessment of glomerular filtration rate in unanesthetized rats using a small animal imager: impact on arterial pressure, heart rate, and activity
  60. Chronic recurrent dehydration associated with periodic water intake exacerbates hypertension and promotes renal damage in male spontaneously hypertensive rats
  61. Anti‐fibrotic actions of relaxin
  62. “You are what you drink!” Focus on “Rehydration with soft drink-like beverages exacerbates dehydration and worsens dehydration-associated renal injury”
  63. Placental Growth Factor
  64. Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney
  65. Epochs in the depressor/pressor balance of the renin–angiotensin system
  66. Angiotensin AT2-receptor stimulation improves survival and neurological outcome after experimental stroke in mice
  67. Accelerated age-related decline in renal and vascular function in female rats following early-life growth restriction
  68. Response to Letters Regarding Article, “Renal Dysfunction Is Associated With a Reduced Contribution of Nitric Oxide and Enhanced Vasoconstriction After a Congenital Renal Mass Reduction in Sheep”
  69. Angiotensin Type 2 Receptor
  70. β-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats
  71. Role of the kidney in the fetal programming of adult cardiovascular disease: an update
  72. Erratum: Reduced sensitivity of the renal vasculature to angiotensin II in young rats: the role of the angiotensin type 2 receptor
  73. Renal Dysfunction Is Associated With a Reduced Contribution of Nitric Oxide and Enhanced Vasoconstriction After a Congenital Renal Mass Reduction in Sheep
  74. Sex Differences in AT2R Expression and Action
  75. High-Dose Estradiol-Replacement Therapy Enhances the Renal Vascular Response to Angiotensin II via an AT2-Receptor Dependent Mechanism
  76. Angiotensin-Based Peptides as AT2R Agonists
  77. AT2R, Vascular Effects, and Blood Pressure
  78. Using stimulation of the diving reflex in humans to teach integrative physiology
  79. Sex- and age-related differences in the chronic pressure-natriuresis relationship: role of the angiotensin type 2 receptor
  80. Pressor responsiveness to angiotensin II in female mice is enhanced with age: role of the angiotensin type 2 receptor
  81. Role of Inflammation and the Angiotensin Type 2 Receptor in the Regulation of Arterial Pressure During Pregnancy in Mice
  82. Reduced sensitivity of the renal vasculature to angiotensin II in young rats: the role of the angiotensin type 2 receptor
  83. Angiotensin Type 2 Receptor Stimulation Increases Renal Function in Female, but Not Male, Spontaneously Hypertensive Rats
  84. Loss of a kidney during fetal life: long-term consequences and lessons learned
  85. Compensatory responses to nephron deficiency: Adaptive or maladaptive?
  86. Impaired ability to modulate glomerular filtration rate in aged female sheep following fetal uninephrectomy
  87. Transgenerational programming of fetal nephron deficits and sex-specific adult hypertension in rats
  88. Sex-Related Differences in Hypertension
  89. Maternal Obesity
  90. Control of salt and volume retention cannot be ruled out as a mechanism underlying the blood pressure-lowering effect of renal denervation
  91. Unmasking the potential of the angiotensin AT2receptor as a therapeutic target in hypertension in men and women: What we know and what we still need to find out
  92. Improvement in Renal Hemodynamics following Combined Angiotensin II Infusion and AT1R Blockade in Aged Female Sheep following Fetal Unilateral Nephrectomy
  93. Undergraduate perceptions of human and anesthetised rabbit cardiovascular physiology practicals
  94. Update on the Angiotensin AT2 Receptor
  95. The “His and Hers” of the Renin-Angiotensin System
  96. Blunted Sodium Excretion in Response to a Saline Load in 5 Year Old Female Sheep Following Fetal Uninephrectomy
  97. Sex differences in the renal vascular response to angiotensin II involves the Mas receptor
  98. Increased Cardiovascular and Renal Risk Is Associated with Low Nephron Endowment in Aged Females: An Ovine Model of Fetal Unilateral Nephrectomy
  99. Long-Term Alteration in Maternal Blood Pressure and Renal Function After Pregnancy in Normal and Growth-Restricted Rats
  100. Effects of tempol and candesartan on neural control of the kidney
  101. Renal responses to furosemide are significantly attenuated in male sheep at 6 months of age following fetal uninephrectomy
  102. The angiotensin type 2 receptor weighs in on obesity: a promising therapeutic target?
  103. Sex-Specific Influence of Angiotensin Type 2 Receptor Stimulation on Renal Function
  104. Postnatal Ontogeny of Angiotensin Receptors and ACE2 in Male and Female Rats
  105. In the arms of Morpheus
  106. Differential Mechanisms of Ang (1-7)-Mediated Vasodepressor Effect in Adult and Aged Candesartan-Treated Rats
  107. Sex Differences in the Pressor and Tubuloglomerular Feedback Response to Angiotensin II
  108. The arterial depressor response to chronic low-dose angiotensin II infusion in female rats is estrogen dependent
  109. Urine-concentrating defects exacerbate with age in male offspring with a low-nephron endowment
  110. The renin–angiotensin system
  111. Fetal uninephrectomy in male sheep alters the systemic and renal responses to angiotensin II infusion and AT1R blockade
  112. Induction of hyperglycemia in adult intrauterine growth-restricted rats: effects on renal function
  113. Renal programming: cause for concern?
  114. Gender Differences in Pressure-Natriuresis and Renal Autoregulation
  115. Prenatal Exposure to Alcohol Reduces Nephron Number and Raises Blood Pressure in Progeny
  116. High-salt diet reveals the hypertensive and renal effects of reduced nephron endowment
  117. Chronic maternal hypertension affects placental gene expression and differentiation in rabbits
  118. Chronic maternal hypertension characterized by renal dysfunction is associated with reduced placental blood flow during late gestation in rabbits
  119. Reduced nephron endowment due to fetal uninephrectomy impairs renal sodium handling in male sheep
  120. Review: Sex specific programming: A critical role for the renal renin–angiotensin system
  121. Ontogeny of Placental Structural Development and Expression of the Renin–Angiotensin System and 11β-HSD2 Genes in the Rabbit
  122. Glomerular surface area is normalized in mice born with a nephron deficit: no role for AT1receptors
  123. Development of cardiovascular disease due to renal insufficiency in male sheep following fetal unilateral nephrectomy
  124. Developmental programming of a reduced nephron endowment: more than just a baby's birth weight
  125. Response to Can the Study of Female Rats Help Our Understanding of Women?
  126. Enhanced Angiotensin II Type 2 Receptor Mechanisms Mediate Decreases in Arterial Pressure Attributable to Chronic Low-Dose Angiotensin II in Female Rats
  127. SEX-DIFFERENCES IN CIRCADIAN BLOOD PRESSURE VARIATIONS IN RESPONSE TO CHRONIC ANGIOTENSIN II INFUSION IN RATS
  128. Postnatal growth and the tracking of blood pressure
  129. Physiological and molecular mechanisms governing sexual dimorphism of kidney, cardiac, and vascular function
  130. Sex differences in postnatal growth and renal development in offspring of rabbit mothers with chronic secondary hypertension
  131. INTRODUCTION
  132. Can adult cardiovascular disease be programmed in utero?
  133. Lack of contribution of P2X receptors to neurally mediated vasoconstriction in the rabbit kidney in vivo
  134. A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products
  135. Type 1 neuropeptide Y receptors and α1-adrenoceptors in the neural control of regional renal perfusion
  136. Intricacies of brain angiotensin II signalling pathways
  137. Paradoxical structural effects in the unilaterally denervated spontaneously hypertensive rat kidney
  138. New Physiological Targets Within the Kidney for Antihypertensive Therapy
  139. Predominant postglomerular vascular resistance response to reflex renal sympathetic nerve activation during ANG II clamp in rabbits
  140. Prostaglandins and nitric oxide in regional kidney blood flow responses to renal nerve stimulation
  141. EFFECT OF ENDOTHELIN-1 ON REGIONAL KIDNEY BLOOD FLOW AND RENAL ARTERIOLE CALIBRE IN RABBITS
  142. Mechanisms underlying the differential control of blood flow in the renal medulla and cortex
  143. DIFFERENTIAL NEURAL CONTROL OF GLOMERULAR ULTRAFILTRATION
  144. NEURAL CONTROL OF RENAL MEDULLARY PERFUSION
  145. Effects of early carvedilol treatment and withdrawal on the development of hypertension and renal vascular narrowing
  146. Nitric oxide in responses of regional kidney perfusion to renal nerve stimulation and renal ischaemia
  147. Adult Rabbit Offspring of Mothers With Secondary Hypertension Have Increased Blood Pressure
  148. Preglomerular and Postglomerular Resistance Responses to Different Levels of Sympathetic Activation by Hypoxia
  149. Metalloendopeptidases EC 3.4.24.15 and EC 3.4.24.16 And Bradykinin B2 Receptors Do Not Play Important Roles In Renal Wrap Hypertension In Rabbits
  150. Chronic angiotensin converting enzyme inhibition enhances renal vascular responsiveness to acetylcholine in anaesthetized rabbits
  151. Effects of activation of vasopressin-V1-receptors on regional kidney blood flow and glomerular arteriole diameters
  152. Glomerular hypertension and hyperfiltration in adrenocorticotrophin-induced hypertension in rats: the role of nitric oxide
  153. Differential control of intrarenal blood flow during reflex increases in sympathetic nerve activity
  154. Renovascular Hypertension
  155. Diversity of responses of renal cortical and medullary blood flow to vasoconstrictors in conscious rabbits
  156. Sex differences in pressure diuresis/natriuresis in rabbits
  157. Blood flow in the glomerular capillary network
  158. Intrarenal haemodynamic and glomerular responses to inhibition of nitric oxide formation in rabbits.
  159. RENAL DENERVATION POTENTIATES THE NATRIURETIC AND DIURETIC EFFECTS OF ATRIAL NATRIURETIC PEPTIDE IN ANAESTHETIZED RABBITS
  160. Glomerular ultrafiltration in rabbits with superficial glomeruli
  161. Evidence for a renomedullary vasodepressor system in rabbits and dogs.
  162. VASCULAR ACTIONS OF ENDOTHELIN IN THE RABBIT KIDNEY
  163. RENAL VENOUS WEDGE PRESSURE IN RENAL WRAP HYPERTENSION IN RABBITS
  164. Renal Effects of Atrial Natriuretic Peptide in Conscious Rabbits with Renal Wrap Hypertension
  165. DECREASED RENAL RESPONSES TO ATRIAL NATRIURETIC PEPTIDE IN RENAL WRAP HYPERTENSION
  166. Effect of Renal Denervation on the Development of Cellophane-Wrap Hypertension in Rabbits
  167. Programming Hypertension—Animal Models