All Stories

  1. Properties of Triheteromeric N-Methyl-d-Aspartate Receptors Containing Two Distinct GluN1 Isoforms
  2. Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits
  3. Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site
  4. Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites
  5. Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-bromophenyl-ACEPC
  6. Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-fluorophenyl-ACEPC
  7. Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-(3-fluoropropyl)phenyl-ACEPC
  8. Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties
  9. Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains
  10. Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains with MPX 007
  11. GLUTAMATE- AND GLYCINE-BOUND GLUN1/GLUN2A AGONIST BINDING DOMAINS WITH MPX-004
  12. Glutamate- and DCKA-bound GluN1/GluN2A agonist binding domains with MPX-007
  13. Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-fluorophenyl-ACEPC
  14. Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, phenyl-ACEPC
  15. Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-bromophenyl-ACEPC
  16. Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-(3-fluoropropyl)phenyl-ACEPC
  17. Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors
  18. Pharmacology of triheteromeric N -Methyl- d -Aspartate Receptors
  19. Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors
  20. Correction to “Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators”
  21. Binding of ArgTX-636 in the NMDA Receptor Ion Channel
  22. Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator
  23. Glutamate receptors: Mechanistic twists and turns
  24. Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors
  25. Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy
  26. A Human Mutation in the M4 Helix of GluN2A Accelerates Forward Gating Transitions in NMDA Receptors
  27. Structure-based discovery of antagonists for GluN3-containing N-methyl-d-aspartate receptors
  28. Crystal Structure and Pharmacological Characterization of a NovelN-Methyl-d-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site
  29. Modal gating of GluN1/GluN2D NMDA receptors
  30. GluN2D ligand-binding core in complex with propyl-NHP5G
  31. GluN2A ligand-binding core in complex with propyl-NHP5G
  32. Development of 2′-Substituted (2S,1′R,2′S)-2-(Carboxycyclopropyl)glycine Analogues as PotentN-Methyl-d-aspartic Acid Receptor Agonists
  33. Structural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-d-Aspartate Receptors
  34. Molecular pharmacology of human NMDA receptors
  35. GluN1 splice variant control of GluN1/GluN2D NMDA receptors
  36. Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors
  37. Molecular Determinants for Subtype-Selective Ion Channel Block of NMDA Receptors by Argiotoxin Analogs
  38. 6.2 Structure-Function Correlates of Glutamate-Gated Ion Channels
  39. Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective Modulators
  40. How Glutamate Receptor Subunits Mix and Match: Details Uncovered
  41. ChemInform Abstract: Partial Agonists and Subunit Selectivity at NMDA Receptors.
  42. Structural and Mechanistic Determinants of a Novel Site for Noncompetitive Inhibition of GluN2D-Containing NMDA Receptors
  43. Partial Agonists and Subunit Selectivity at NMDA Receptors
  44. A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
  45. Glutamate Receptor Ion Channels: Structure, Regulation, and Function
  46. Novel 3-Carboxy- and 3-Phosphonopyrazoline Amino Acids as Potent and Selective NMDA Receptor Antagonists: Design, Synthesis, and Pharmacological Characterization
  47. Control of Assembly and Function of Glutamate Receptors by the Amino-Terminal Domain
  48. 4-Hydroxy-1,2,5-oxadiazol-3-yl Moiety as Bioisoster of the Carboxy Function. Synthesis, Ionization Constants, and Molecular Pharmacological Characterization at Ionotropic Glutamate Receptors of Compounds Related to Glutamate and Its Homologues
  49. Activation of Recombinant Rat GluN1/gluN2D NMDA Receptors
  50. Subunit-Specific Activation of NMDA Receptors
  51. Mutational Mapping and Modeling of the Binding Site for (S)-Citalopram in the Human Serotonin Transporter
  52. Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain
  53. An allosteric binding site at the human serotonin transporter mediates the inhibition of escitalopram by R-citalopram: Kinetic binding studies with the ALI/VFL–SI/TT mutant
  54. Location of the Antidepressant Binding Site in the Serotonin Transporter
  55. Modulation of the Dimer Interface at Ionotropic Glutamate-Like Receptor  2 by D-Serine and Extracellular Calcium
  56. Stereocontrolled Synthesis and Pharmacological Evaluation of Azetidine-2,3-Dicarboxylic Acids at NMDA Receptors
  57. N-Hydroxypyrazolyl Glycine Derivatives as SelectiveN-Methyl-d-aspartic Acid Receptor Ligands
  58. Pharmacological Characterization of Ligands at Recombinant NMDA Receptor Subtypes by Electrophysiological Recordings and Intracellular Calcium Measurements
  59. Ionotropic glutamate-like receptor δ2 binds d -serine and glycine
  60. Structural aspects of AMPA receptor activation, desensitization and deactivation
  61. Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid
  62. Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
  63. The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid
  64. (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic Acid, a Potent and Selective Agonist at the GluR5 Subtype of Ionotropic Glutamate Receptors. Synthesis, Modeling, and Molecular Pharmacology
  65. Structure and Function of the NMDA Receptor
  66. Structural Correlates of Ionotropic Glutamate Receptor Function