Kasper Hansen
Univesity of Montana
My Publications
Properties of Triheteromeric N-Methyl-d-Aspartate Receptors Containing Two Distinct Glu...
Molecular Pharmacology
February 2018
Structural basis of subunit selectivity for competitive NMDA receptor antagonists with ...
Proceedings of the National Academy of Sciences
July 2017
Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist...
Molecular Pharmacology
June 2017
Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites
ACS Chemical Neuroscience
May 2017
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine an...
April 2017
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine an...
April 2017
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine an...
April 2017
Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in...
Neuron
April 2017
Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains
September 2016
Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains with MPX 007
September 2016
GLUTAMATE- AND GLYCINE-BOUND GLUN1/GLUN2A AGONIST BINDING DOMAINS WITH MPX-004
September 2016
Glutamate- and DCKA-bound GluN1/GluN2A agonist binding domains with MPX-007
September 2016
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine an...
September 2016
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine an...
September 2016
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine an...
September 2016
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine an...
September 2016
Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors
Neuron
September 2016
Pharmacology of triheteromeric N -Methyl- d -Aspartate Receptors
Neuroscience Letters
March 2016
Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Gluta...
Molecular Pharmacology
December 2015
Correction to “Design, Synthesis, and Structure–Activity Relationship of a Novel Series...
Journal of Medicinal Chemistry
March 2015
Binding of ArgTX-636 in the NMDA Receptor Ion Channel
Journal of Molecular Biology
January 2015
Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Pos...
Molecular Pharmacology
September 2014
Glutamate receptors: Mechanistic twists and turns
Nature Methods
August 2014
Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2...
Neuron
March 2014
Functional analysis of a de novo GRIN2A missense mutation associated with early-onset e...
Nature Communications
February 2014
A Human Mutation in the M4 Helix of GluN2A Accelerates Forward Gating Transitions in NM...
Biophysical Journal
January 2014
Structure-based discovery of antagonists for GluN3-containing N-methyl-d-aspartate rece...
Neuropharmacology
December 2013
Crystal Structure and Pharmacological Characterization of a NovelN-Methyl-d-aspartate (...
Journal of Biological Chemistry
September 2013
Modal gating of GluN1/GluN2D NMDA receptors
Neuropharmacology
August 2013
GluN2D ligand-binding core in complex with propyl-NHP5G
May 2013
GluN2A ligand-binding core in complex with propyl-NHP5G
May 2013
Development of 2′-Substituted (2S,1′R,2′S)-2-(Carboxycyclopropyl)glycine Analogues as P...
Journal of Medicinal Chemistry
May 2013
Structural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-d...
Molecular Pharmacology
April 2013
Molecular pharmacology of human NMDA receptors
Neurochemistry International
September 2012
GluN1 splice variant control of GluN1/GluN2D NMDA receptors
The Journal of Physiology
June 2012
Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors
Journal of Neuroscience
May 2012
Molecular Determinants for Subtype-Selective Ion Channel Block of NMDA Receptors by Arg...
Biophysical Journal
January 2012
6.2 Structure-Function Correlates of Glutamate-Gated Ion Channels
January 2012
Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor...
Molecular Pharmacology
August 2011
How Glutamate Receptor Subunits Mix and Match: Details Uncovered
Neuron
July 2011
ChemInform Abstract: Partial Agonists and Subunit Selectivity at NMDA Receptors.
ChemInform
March 2011
Structural and Mechanistic Determinants of a Novel Site for Noncompetitive Inhibition o...
Journal of Neuroscience
March 2011
Partial Agonists and Subunit Selectivity at NMDA Receptors
Chemistry - A European Journal
October 2010
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
Nature Communications
October 2010
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
Pharmacological Reviews
August 2010
Novel 3-Carboxy- and 3-Phosphonopyrazoline Amino Acids as Potent and Selective NMDA Rec...
ChemMedChem
July 2010
Control of Assembly and Function of Glutamate Receptors by the Amino-Terminal Domain
Molecular Pharmacology
July 2010
4-Hydroxy-1,2,5-oxadiazol-3-yl Moiety as Bioisoster of the Carboxy Function. Synthesis,...
Journal of Medicinal Chemistry
May 2010
Activation of Recombinant Rat GluN1/gluN2D NMDA Receptors
Biophysical Journal
January 2010
Subunit-Specific Activation of NMDA Receptors
Biophysical Journal
January 2010
Mutational Mapping and Modeling of the Binding Site for (S)-Citalopram in the Human Ser...
Journal of Biological Chemistry
November 2009
Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain
Journal of Neuroscience
September 2009
An allosteric binding site at the human serotonin transporter mediates the inhibition o...
Neuroscience Letters
September 2009
Location of the Antidepressant Binding Site in the Serotonin Transporter
Journal of Biological Chemistry
February 2009
Modulation of the Dimer Interface at Ionotropic Glutamate-Like Receptor 2 by D-Serine ...
Journal of Neuroscience
January 2009
Stereocontrolled Synthesis and Pharmacological Evaluation of Azetidine-2,3-Dicarboxylic...
ChemMedChem
January 2009
N-Hydroxypyrazolyl Glycine Derivatives as SelectiveN-Methyl-d-aspartic Acid Receptor Li...
Journal of Medicinal Chemistry
July 2008
Pharmacological Characterization of Ligands at Recombinant NMDA Receptor Subtypes by El...
Combinatorial Chemistry & High Throughput Screening
May 2008
Ionotropic glutamate-like receptor 2 binds D-serine and glycine
Proceedings of the National Academy of Sciences
August 2007
Structural aspects of AMPA receptor activation, desensitization and deactivation
Current Opinion in Neurobiology
June 2007
Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ...
Organic & Biomolecular Chemistry
January 2007
Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
Molecular Pharmacology
August 2005
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ...
European Journal of Pharmacology
September 2004
(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic Acid, a Po...
Journal of Medicinal Chemistry
April 2003
Structure and Function of the NMDA Receptor
Structural Correlates of Ionotropic Glutamate Receptor Function
