All Stories

  1. Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies

    Article • Proceedings of the National Academy of Sciences, July 2023, Proceedings of the National Academy of Sciences

    Karl Wittrup

  2. Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies

    Article • Proceedings of the National Academy of Sciences, August 2022, Proceedings of the National Academy of Sciences

    Karl Wittrup

  3. Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice

    Article • PLoS ONE, April 2021, PLOS

    Karl Wittrup

  4. Connecting the sequence dots: shedding light on the genesis of antibodies reported to be designed in silico

    Article • mAbs, May 2019, Taylor & Francis

    Karl Wittrup

  5. Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models

    Article • OncoImmunology, February 2019, Taylor & Francis

    Karl Wittrup

  6. Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed on Yeast

    Article • Journal of Molecular Biology, January 2013, Elsevier

    Karl Wittrup