All Stories

  1. Implementing an integrated epistemic framework: A Multimodal active learning approach in translational neuroscience

    Article • AJP Advances in Physiology Education, November 2025, American Physiological Society

    Dr Kambiz N Alavian

  2. Paradigm shifts as portals to threshold concepts and epistemic transformation

    Article • Educational Philosophy and Theory, July 2025, Taylor & Francis

    Dr Kambiz N Alavian

  3. Reduced DJ-1-F1Fo ATP synthase association correlates with midbrain dopaminergic neuron vulnerability in idiopathic Parkinson’s disease

    Article • Science Advances, June 2025, American Association for the Advancement of Science

    Dr Kambiz N Alavian

  4. International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus

    Article • GeroScience, February 2025, Springer Science + Business Media

    Dr Kambiz N Alavian

  5. Defining an ageing-related pathology, disease or syndrome: International Consensus Statement

    Article • GeroScience, September 2024, Springer Science + Business Media

    Dr Ian van der Linde, Dr Kambiz N Alavian

  6. Defining an Ageing-Related Pathology, Disease or Syndrome: International Consensus Statement

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr Kambiz N Alavian

  7. Mitochondrial leak metabolism induces the Spemann-Mangold Organizer via Hif-1α in Xenopus

    Article • Developmental Cell, November 2023, Elsevier

    Dr Kambiz N Alavian

  8. Initial experience with magnetic resonance–guided focused ultrasound stereotactic surgery for central brain lesions in young adults

    Article • Journal of Neurosurgery, September 2022, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr Kambiz N Alavian

  9. CAV2.3 expression is upregulated in the substantia nigra pars compacta of humans with Parkinson's disease

    Article • Brain Disorders, March 2022, Elsevier

    Dr Kambiz N Alavian

  10. Retraction to: The Subcellular Expression Patterns of BCL-XL in Primary Brain Tumour Samples

    Article • BJS, May 2021, Oxford University Press (OUP)

    Dr Kambiz N Alavian

  11. Threshold Concepts in Neuroscience: Identification Challenges, Educational Opportunities and Recommendations for Practice

    Article • Frontiers in Education, March 2021, Frontiers

    Dr Kambiz N Alavian

  12. The factors for the early and late development of midbrain dopaminergic neurons segregate into two distinct evolutionary clusters

    Article • Brain Disorders, March 2021, Elsevier

    Dr Kambiz N Alavian

  13. Disorders of the brain, paradoxes of the enigma

    Article • Brain Disorders, March 2021, Elsevier

    Dr Kambiz N Alavian

  14. Nanoparticle-Based Gene Therapy Intervention for Stroke Treatment: A Systematic Review

    Article • Current Gene Therapy, December 2020, Bentham Science Publishers

    sorayya ghasemi, firoozeh Alavian, Dr Kambiz N Alavian

  15. PhySpeTree: an automated pipeline for reconstructing phylogenetic species trees

    Article • BMC Evolutionary Biology, December 2019, Springer Science + Business Media

    Dr Kambiz N Alavian

  16. Parkinson’s disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth

    Article • Cell Death and Disease, June 2019, Springer Science + Business Media

    Dr Kambiz N Alavian

  17. The mitochondrial metabolic function of DJ-1 is modulated by 14-3-3β

    Article • The FASEB Journal, April 2019, Federation of American Societies For Experimental Biology (FASEB)

    Dr Kambiz N Alavian

  18. Post mortem examination of Parkinson’s disease brains suggests decline in mitochondrial biomass, reversed by deep brain stimulation of subthalamic nucleus

    Article • The FASEB Journal, March 2019, Federation of American Societies For Experimental Biology (FASEB)

    Dr Kambiz N Alavian

  19. Phylogenetic Profiling of Mitochondrial Proteins and Integration Analysis of Bacterial Transcription Units Suggest Evolution of F1Fo ATP Synthase from Multiple Modules

    Article • Journal of Molecular Evolution, November 2017, Springer Science + Business Media

    Dr Kambiz N Alavian

  20. PrePhyloPro: phylogenetic profile-based prediction of whole proteome linkages

    Article • PeerJ, August 2017, PeerJ

    Dr Kambiz N Alavian

  21. Inhibition of Bcl-xL prevents pro-death actions of ΔN-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity

    Article • Cell Death and Differentiation, August 2017, Springer Science + Business Media

    Dr Kambiz N Alavian

  22. Mitochondria and Memory: Bioenergetics, Synaptic Plasticity and Neurodegeneration

    Article • Biophysical Journal, February 2017, Elsevier

    Dr Kambiz N Alavian

  23. The Mitochondrial Permeability Transition Pore: Molecular Structure and Function in Health and Disease

    Article • January 2017, Springer Science + Business Media

    Dr Kambiz N Alavian

  24. PTP and LTP: The physiological role of the permeability transition pore in learning and memory

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, August 2016, Elsevier

    Dr Kambiz N Alavian

  25. Physiological roles of the mitochondrial permeability transition pore

    Article • Journal of Bioenergetics and Biomembranes, February 2016, Springer Science + Business Media

    Dr Kambiz N Alavian

  26. The Mitochondrial Permeability Transition Pore and ATP Synthase

    Article • January 2016, Springer Science + Business Media

    Dr Kambiz N Alavian

  27. Erratum to: The Mitochondrial Permeability Transition Pore and ATP Synthase

    Article • January 2016, Springer Science + Business Media

    Dr Kambiz N Alavian

  28. Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress

    Article • PLoS Biology, October 2015, PLOS

    Dr Kambiz N Alavian

  29. The Mitochondrial Permeability Transition Pore, the c-Subunit of the F1FoATP Synthase, Cellular Development, and Synaptic Efficiency

    Article • September 2015, Wiley

    Dr Kambiz N Alavian

  30. Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F1FO ATP synthase

    Article • Pharmacological Research, September 2015, Elsevier

    Dr Kambiz N Alavian

  31. Iron Homeostasis and Pulmonary Hypertension

    Article • Circulation Research, May 2015, Wolters Kluwer Health

    Dr Kambiz N Alavian

  32. Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

    Article • Journal of Visualized Experiments, March 2015, MyJove Corporation

    Dr Kambiz N Alavian

  33. Isolation, Culture and Long-Term Maintenance of Primary Mesencephalic Dopaminergic Neurons From Embryonic Rodent Brains

    Article • Journal of Visualized Experiments, February 2015, MyJove Corporation

    Dr Kambiz N Alavian

  34. Bcl-xL Is Necessary for Neurite Outgrowth in Hippocampal Neurons

    Article • Antioxidants & Redox Signaling, January 2015, Mary Ann Liebert Inc

    Dr Kambiz N Alavian

  35. The Mitochondrial Complex V–Associated Large-Conductance Inner Membrane Current Is Regulated by Cyclosporine and Dexpramipexole

    Article • Molecular Pharmacology, October 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Kambiz N Alavian

  36. Bcl-xL in neuroprotection and plasticity

    Article • Frontiers in Physiology, September 2014, Frontiers

    Dr Kambiz N Alavian

  37. An uncoupling channel within the c-subunit ring of the F 1 F O ATP synthase is the mitochondrial permeability transition pore

    Article • Proceedings of the National Academy of Sciences, June 2014, Proceedings of the National Academy of Sciences

    Dr Kambiz N Alavian

  38. The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed

    Article • Journal of Biomedical Science, January 2014, Springer Science + Business Media

    Dr Kambiz N Alavian

  39. The C-Subunit of the ATP Synthase Forms the Pore of the PTP

    Article • Biophysical Journal, January 2014, Elsevier

    Dr Kambiz N Alavian

  40. A Bcl-xL–Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis

    Article • Nature Cell Biology, June 2013, Springer Science + Business Media

    Dr Kambiz N Alavian

  41. F1FO ATPase Vesicle Preparation and Technique for Performing Patch Clamp Recordings of Submitochondrial Vesicle Membranes

    Article • Journal of Visualized Experiments, May 2013, MyJove Corporation

    Dr Kambiz N Alavian

  42. DJ1 regulates Neuronal Mitochondrial Bioenergetic Efficiency

    Article • Biophysical Journal, January 2013, Elsevier

    Dr Kambiz N Alavian

  43. NAD kinase regulates the size of the NADPH pool and insulin secretion in pancreatic β-cells

    Article • AJP Endocrinology and Metabolism, July 2012, American Physiological Society

    Dr Kambiz N Alavian

  44. Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency

    Article • Brain Research, March 2012, Elsevier

    Dr Kambiz N Alavian

  45. N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death

    Article • Nature Neuroscience, February 2012, Springer Science + Business Media

    Dr Kambiz N Alavian

  46. The C-Subunit Ring of the F1FO ATP Synthase Constitutes a Leak Channel that Regulates Cellular Metabolic Efficiency by Counteracting the H+ Translocator

    Article • Biophysical Journal, January 2012, Elsevier

    Dr Kambiz N Alavian

  47. Erratum: Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase

    Article • Nature Cell Biology, November 2011, Springer Science + Business Media

    Dr Kambiz N Alavian

  48. Bcl-xLregulates mitochondrial energetics by stabilizing the inner membrane potential

    Article • Journal of Cell Biology, October 2011, Rockefeller University Press

    Dr Kambiz N Alavian

  49. Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase

    Article • Nature Cell Biology, September 2011, Springer Science + Business Media

    Dr Kambiz N Alavian

  50. Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum

    Article • Journal of Neurosurgery, March 2011, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr Kambiz N Alavian

  51. Bcl-xL Determines the Metabolic Efficiency of Neurons, through Interaction with Mitochondrial ATP Synthase

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Kambiz N Alavian

  52. Decrease in a Leak Conductance Associated with Mitochondrial Complex V and Improved Bioenergetic Efficiency may Underlie Cytoprotection of at-Risk Neurons by Dexpramipexole

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Kambiz N Alavian

  53. The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons

    Article • Brain, June 2010, Oxford University Press (OUP)

    Dr Kambiz N Alavian

  54. BCL-xL Regulates ATP Synthase and Synaptic Efficiency

    Article • Biophysical Journal, January 2010, Elsevier

    Dr Kambiz N Alavian

  55. Parkinson's disease candidate gene prioritization based on expression profile of midbrain dopaminergic neurons

    Article • Journal of Biomedical Science, January 2010, Springer Science + Business Media

    Dr Kambiz N Alavian

  56. CD15, CD24 and CD29 Define a Surface Biomarker Code for Neural Lineage Differentiation of Stem Cells

    Article • Stem Cells, January 2009, Wiley

    Dr Kambiz N Alavian

  57. Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression

    Article • Neural Development, January 2009, Springer Science + Business Media

    Dr Kambiz N Alavian

  58. Linkage of cDNA expression profiles of mesencephalic dopaminergic neurons to a genome-wide in situ hybridization database

    Article • Molecular Neurodegeneration, January 2009, Springer Science + Business Media

    Dr Kambiz N Alavian

  59. Transcriptional Regulation of Their Survival:

    Article • January 2009, Springer Science + Business Media

    Dr Kambiz N Alavian

  60. Transcriptional regulation of mesencephalic dopaminergic neurons: The full circle of life and death

    Article • Movement Disorders, January 2008, Wiley

    Dr Kambiz N Alavian

  61. Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice

    Article • Proceedings of the National Academy of Sciences, October 2006, Proceedings of the National Academy of Sciences

    Dr Kambiz N Alavian

  62. The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta

    Article • Journal of Neurochemistry, November 2004, Wiley

    Dr Kambiz N Alavian

  63. Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes

    Article • Journal of Cell Science, September 2003, The Company of Biologists

    Dr Kambiz N Alavian