All Stories

  1. An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth

    Article • Nature Communications, November 2014, Springer Science + Business Media

    Dr Kai Ge

  2. Gcn5 and PCAF negatively regulate interferon-  production through HAT-independent inhibition of TBK1

    Article • EMBO Reports, September 2014, EMBO

    Dr Kai Ge

  3. Gcn5 and PCAF Regulate PPAR  and Prdm16 Expression To Facilitate Brown Adipogenesis

    Article • Molecular and Cellular Biology, July 2014, ASM Journals

    Dr Kai Ge

  4. Loss of function of mouse Pax‐Interacting Protein 1‐associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development

    Article • Developmental Dynamics, April 2014, Wiley

    Dr Kai Ge

  5. Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis

    Article • Cell & Bioscience, January 2014, Springer Science + Business Media

    Dr Kai Ge

  6. H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

    Article • eLife, December 2013, eLife

    Vittorio Sartorelli, Dr Kai Ge

  7. Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis

    Article • The EMBO Journal, November 2012, Springer Science + Business Media

    Dr Kai Ge

  8. Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

    Article • Proceedings of the National Academy of Sciences, October 2012, Proceedings of the National Academy of Sciences

    Dr Kai Ge

  9. UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity

    Article • Proceedings of the National Academy of Sciences, September 2012, Proceedings of the National Academy of Sciences

    Dr Kai Ge

  10. Epigenetic regulation of adipogenesis by histone methylation

    Article • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, July 2012, Elsevier

    Dr Kai Ge

  11. EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR

    Article • Cancer Research, November 2011, American Association for Cancer Research (AACR)

    Dr Kai Ge

  12. Affi nity Purifi cation of MLL3/MLL4 Histone H3K4 Methyltransferase Complex

    Article • October 2011, Springer Science + Business Media

    Dr Kai Ge

  13. Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

    Article • The EMBO Journal, December 2010, Springer Science + Business Media

    Dr Kai Ge

  14. Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

    Article • Proceedings of the National Academy of Sciences, April 2010, Proceedings of the National Academy of Sciences

    Dr Kai Ge

  15. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

    Article • The EMBO Journal, March 2010, Springer Science + Business Media

    Dr Kai Ge

  16. Histone Methylation Regulator PTIP Is Required for PPARγ and C/EBPα Expression and Adipogenesis

    Article • Cell Metabolism, July 2009, Elsevier

    Dr Kai Ge

  17. Accumulation of Pax2 Transactivation Domain Interaction Protein (PTIP) at Sites of DNA Breaks via RNF8-dependent Pathway Is Required for Cell Survival after DNA Damage

    Article • Journal of Biological Chemistry, January 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Kai Ge

  18. Alternative Mechanisms by Which Mediator Subunit MED1/TRAP220 Regulates Peroxisome Proliferator-Activated Receptor γ-Stimulated Adipogenesis and Target Gene Expression

    Article • Molecular and Cellular Biology, November 2007, ASM Journals

    Dr Kai Ge, Markus Kalkum

  19. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases

    Article • Proceedings of the National Academy of Sciences, November 2007, Proceedings of the National Academy of Sciences

    Dr Kai Ge

  20. PTIP Associates with MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase Complex

    Article • Journal of Biological Chemistry, May 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Kai Ge, Markus Kalkum

  21. The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis

    Article • Molecular Cell, October 2003, Elsevier

    Dr Kai Ge

  22. Med1/TRAP220 is essential for adipogenesis

    Article • Nature, May 2002, Springer Science + Business Media

    Dr Kai Ge