All Stories

  1. Transcriptomic Analysis of Extracellular Vesicles in the Search for Novel Plasma and Thrombus Biomarkers of Ischemic Stroke Etiologies

    Article • International Journal of Molecular Sciences, April 2024, MDPI AG

    Jose A. Rodriguez

  2. Role of factor XIII in ischemic stroke: a key molecule promoting thrombus stabilization and resistance to lysis

    Article • Journal of Thrombosis and Haemostasis, April 2024, Elsevier

    Jose A. Rodriguez

  3. Trimethylamine N-Oxide as a Mediator Linking Peripheral to Central Inflammation: An In Vitro Study

    Article • International Journal of Molecular Sciences, December 2023, MDPI AG

    Jose A. Rodriguez

  4. Role of LCN2 in a murine model of hindlimb ischemia and in peripheral artery disease patients, and its potential regulation by miR-138-5P

    Article • Atherosclerosis, November 2023, Elsevier

    Jose A. Rodriguez

  5. Loss of the matrix metalloproteinase-10 causes premature features of aging in satellite cells

    Article • Frontiers in Cell and Developmental Biology, May 2023, Frontiers

    Jose A. Rodriguez

  6. Photodynamic nasal SARS-CoV-2 decolonization shortens infectivity and influences specific T-Cell responses

    Article • Frontiers in Cellular and Infection Microbiology, January 2023, Frontiers

    Jose A. Rodriguez

  7. Matrix Metalloproteinase 10 Contributes to Choroidal Neovascularisation

    Article • Biomedicines, June 2022, MDPI AG

    Jose A. Rodriguez

  8. Lipocalin-2 and Calprotectin Potential Prognosis Biomarkers in Peripheral Arterial Disease

    Article • European Journal of Vascular and Endovascular Surgery, April 2022, Elsevier

    Jose A. Rodriguez

  9. CM-352 Efficacy in a Mouse Model of Anticoagulant-Associated Intracranial Hemorrhage

    Article • Thrombosis and Haemostasis, February 2022, Thieme Publishing Group

    Jose A. Rodriguez

  10. Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice

    Article • Journal of Bone and Mineral Research, November 2021, Oxford University Press (OUP)

    Jose A. Rodriguez

  11. Validation of a rapid antigen test as a screening tool for SARS-CoV-2 infection in asymptomatic populations. Sensitivity, specificity and predictive values

    Article • EClinicalMedicine, July 2021, Elsevier

    Jose A. Rodriguez

  12. The Bone Regeneration Capacity of BMP-2 + MMP-10 Loaded Scaffolds Depends on the Tissue Status

    Article • Pharmaceutics, June 2021, MDPI AG

    Jose A. Rodriguez

  13. Association of SDF1 and MMP12 with Atherosclerosis and Inflammation: Clinical and Experimental Study

    Article • Life, May 2021, MDPI AG

    Jose A. Rodriguez

  14. Inner ear drug delivery through a cochlear implant: Pharmacokinetics in a Macaque experimental model

    Article • Hearing Research, May 2021, Elsevier

    Jose A. Rodriguez

  15. Association of calprotectin with other inflammatory parameters in the prediction of mortality for ischemic stroke

    Article • Journal of Neuroinflammation, January 2021, Springer Science + Business Media

    Jose A. Rodriguez

  16. Circulating TIMP-1 is associated with hematoma volume in patients with spontaneous intracranial hemorrhage

    Article • Scientific Reports, June 2020, Springer Science + Business Media

    Jose A. Rodriguez

  17. A Role for MMP-10 (Matrix Metalloproteinase-10) in Calcific Aortic Valve Stenosis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2020, Wolters Kluwer Health

    Jose A. Rodriguez

  18. Elevated circulating metalloproteinase 7 predicts recurrent cardiovascular events in patients with carotid stenosis: a prospective cohort study

    Article • BMC Cardiovascular Disorders, February 2020, Springer Science + Business Media

    Jose A. Rodriguez

  19. MMP-10 is Increased in Early Stage Diabetic Kidney Disease and can be Reduced by Renin-Angiotensin System Blockade

    Article • Scientific Reports, January 2020, Springer Science + Business Media

    Jose A. Rodriguez

  20. Functional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD)

    Article • Journal of Extracellular Vesicles, January 2020, Taylor & Francis

    Jose A. Rodriguez

  21. Trimethylamine-N-Oxide (TMAO) Predicts Cardiovascular Mortality in Peripheral Artery Disease

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Jose A. Rodriguez

  22. Galectin-3 as a novel biotarget in cardiovascular alterations associated to development of severe aortic stenosis

    Article • Anales del Sistema Sanitario de Navarra, August 2019, Gobierno de Navarra

    Jose A. Rodriguez

  23. High serum levels of tissue inhibitor of matrix metalloproteinase-1 during the first week of a malignant middle cerebral artery infarction in non-surviving patients

    Article • BMC Neurology, July 2019, Springer Science + Business Media

    Jose A. Rodriguez

  24. Persistently high circulating tissue inhibitor of matrix metalloproteinase-1 levels in non-survivor brain trauma injury patients

    Article • Journal of Critical Care, June 2019, Elsevier

    Jose A. Rodriguez

  25. Análisis de subpoblaciones monocitarias en relación con los factores de riesgo cardiovascular

    Article • Clínica e Investigación en Arteriosclerosis, April 2019, Elsevier

    Jose A. Rodriguez

  26. Matrix metalloproteinase-10 deficiency delays atherosclerosis progression and plaque calcification

    Article • Atherosclerosis, November 2018, Elsevier

    Jose A. Rodriguez, Prof. Vicente Andrés

  27. Selective increase of cardiomyocyte derived extracellular vesicles after experimental myocardial infarction and functional effects on the endothelium

    Article • Thrombosis Research, October 2018, Elsevier

    Jose A. Rodriguez

  28. MMP10 Promotes Efficient Thrombolysis After Ischemic Stroke in Mice with Induced Diabetes

    Article • Translational Stroke Research, July 2018, Springer Science + Business Media

    Jose A. Rodriguez

  29. Phenotypic Screening To Discover Novel Chemical Series as Efficient Antihemorrhagic Agents

    Article • ACS Medicinal Chemistry Letters, April 2018, American Chemical Society (ACS)

    Jose A. Rodriguez

  30. Combined sustained release of BMP2 and MMP10 accelerates bone formation and mineralization of calvaria critical size defect in mice

    Article • Drug Delivery, January 2018, Taylor & Francis

    Jose A. Rodriguez

  31. Reduced high-density lipoprotein cholesterol: A valuable, independent prognostic marker in peripheral arterial disease

    Article • Journal of Vascular Surgery, November 2017, Elsevier

    Jose A. Rodriguez

  32. CM352 Reduces Brain Damage and Improves Functional Recovery in a Rat Model of Intracerebral Hemorrhage

    Article • Journal of the American Heart Association, June 2017, Wolters Kluwer Health

    Jose A. Rodriguez

  33. New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator

    Article • Cardiovascular Research, April 2017, Oxford University Press (OUP)

    Jose A. Rodriguez

  34. Discovery and Safety Profiling of a Potent Preclinical Candidate, (4-[4-[[(3R)-3-(Hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the Prevention and Treatment of Hemorrhage

    Article • Journal of Medicinal Chemistry, February 2015, American Chemical Society (ACS)

    Jose A. Rodriguez

  35. Association of Sepsis-Related Mortality with Early Increase of TIMP-1/MMP-9 Ratio

    Article • PLOS One, April 2014, PLOS

    Jose A. Rodriguez

  36. Effect of Lutein and Antioxidant Supplementation on VEGF Expression, MMP-2 Activity, and Ultrastructural Alterations in Apolipoprotein E-Deficient Mouse

    Article • Oxidative Medicine and Cellular Longevity, January 2013, Hindawi Publishing Corporation

    Jose A. Rodriguez

  37. Synergistic Effect of Thrombin and CD40 Ligand on Endothelial Matrix Metalloproteinase-10 Expression and Microparticle Generation In Vitro and In Vivo

    Article • Arteriosclerosis Thrombosis and Vascular Biology, April 2012, Wolters Kluwer Health

    Jose A. Rodriguez, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  38. Matrix Metalloproteinase-10 Effectively Reduces Infarct Size in Experimental Stroke by Enhancing Fibrinolysis via a Thrombin-Activatable Fibrinolysis Inhibitor-Mediated Mechanism

    Article • Circulation, November 2011, Wolters Kluwer Health

    Jose A. Rodriguez

  39. Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis

    Article • Critical Care, January 2011, Springer Science + Business Media

    Jose A. Rodriguez

  40. Serum levels of matrix metalloproteinase-10 are associated with the severity of atherosclerosis in patients with chronic kidney disease

    Article • Kidney International, December 2010, Elsevier

    prof alberto ortiz , Dr Jose M Valdivielso, Jose A. Rodriguez

  41. Stromelysin-2 (MMP-10) deficiency does not affect adipose tissue formation in a mouse model of nutritionally induced obesity

    Article • Biochemical and Biophysical Research Communications, November 2009, Elsevier

    Jose A. Rodriguez

  42. Tissue-specific PAI-1 gene expression and glycosylation pattern in insulin-resistant old rats

    Article • AJP Regulatory Integrative and Comparative Physiology, September 2009, American Physiological Society

    Jose A. Rodriguez

  43. Matrix Metalloproteinase-10 Is Upregulated by Thrombin in Endothelial Cells and Increased in Patients With Enhanced Thrombin Generation

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2009, Wolters Kluwer Health

    Jose A. Rodriguez, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  44. Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis

    Article • Critical Care, January 2009, Springer Science + Business Media

    Jose A. Rodriguez

  45. Asociación de marcadores inflamatorios y aterosclerosis subclínica en relación con la edad en sujetos sin enfermedad cardiovascular

    Article • Medicina Clínica, September 2008, Elsevier

    Jose A. Rodriguez

  46. Antioxidant effects of vitamins C and E, multivitamin-mineral complex and flavonoids in a model of retinal oxidative stress: The ApoE-deficient mouse

    Article • Experimental Eye Research, March 2008, Elsevier

    Jose A. Rodriguez

  47. Increased thrombin generation after acute versus chronic coronary disease as assessed by the thrombin generation test

    Article • Thrombosis and Haemostasis, January 2008, Schattauer GmbH

    Jose A. Rodriguez

  48. Metalloproteinases and atherothrombosis: MMP-10 mediates vascular remodeling promoted by inflammatory stimuli

    Article • Frontiers in Bioscience, January 2008, Frontiers in Bioscience

    Jose A. Rodriguez, Jose Martinez Gonzalez, Dr Cristina Rodriguez

  49. Egg yolk improves lipid profile, lipid peroxidation and retinal abnormalities in a murine model of genetic hypercholesterolemia

    Article • The Journal of Nutritional Biochemistry, January 2008, Elsevier

    Jose A. Rodriguez

  50. Vulnerable Plaque Versus Vulnerable Patient: Emerging Blood Biomarkers for Risk Stratification

    Article • Endocrine Metabolic & Immune Disorders - Drug Targets, September 2007, Bentham Science Publishers

    Jose A. Rodriguez

  51. Metaloproteasas, remodelado vascular y syndromes aterotrombóticos

    Article • Revista Española de Cardiología, September 2007, Elsevier

    Jose A. Rodriguez

  52. Folic acid and B vitamins improve hyperhomocysteinemia-induced cardiovascular risk profile in renal transplant recipients

    Article • Journal of Thrombosis and Haemostasis, May 2007, Wiley

    Jose A. Rodriguez

  53. Aterosclerosis en las enfermedades inflamatorias

    Article • Medicina Clínica, May 2007, Elsevier

    Jose A. Rodriguez

  54. Phagocytic NADPH Oxidase-Dependent Superoxide Production Stimulates Matrix Metalloproteinase-9: Implications for Human Atherosclerosis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, March 2007, Wolters Kluwer Health

    Jose A. Rodriguez

  55. Independent association of matrix metalloproteinase-10, cardiovascular risk factors and subclinical atherosclerosis

    Article • Journal of Thrombosis and Haemostasis, October 2006, Wiley

    Jose A. Rodriguez

  56. The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin

    Article • Journal of Thrombosis and Haemostasis, August 2006, Wiley

    Jose A. Rodriguez

  57. Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors

    Article • Clinica Chimica Acta, June 2006, Elsevier

    Jose A. Rodriguez

  58. C-Reactive Protein Induces Matrix Metalloproteinase-1 and -10 in Human Endothelial Cells

    Article • Journal of the American College of Cardiology, April 2006, Elsevier

    Jose A. Rodriguez

  59. Polimorfismo 4G/5G del PAI-1 en el síndrome metabólico

    Article • Medicina Clínica, February 2006, Elsevier

    Jose A. Rodriguez

  60. Effects of cryopreservation on the immunogenicity of porcine arterial allografts in early stages of transplant vasculopathy

    Article • Cryobiology, October 2005, Elsevier

    Jose A. Rodriguez

  61. Monocyte Cyclooxygenase-2 Activity: A New Therapeutic Target for Atherosclerosis?

    Article • Current Drug Targets - Cardiovascular & Hematological Disorders, August 2005, Bentham Science Publishers

    Jose A. Rodriguez

  62. Fibrinógeno. Vieja proteína hemostática con nueva función: marcador no invasivo de aterosclerosis subclínica

    Article • Medicina Clínica, May 2005, Elsevier

    Jose A. Rodriguez

  63. Vitamins C and E Reduce Retinal Oxidative Stress and Nitric Oxide Metabolites and Prevent Ultrastructural Alterations in Porcine Hypercholesterolemia

    Article • Investigative Ophthalmology & Visual Science, April 2005, Association for Research in Vision and Ophthalmology (ARVO)

    Jose A. Rodriguez

  64. Vitamins C and E prevent endothelial VEGF and VEGFR-2 overexpression induced by porcine hypercholesterolemic LDL

    Article • Cardiovascular Research, February 2005, European Society of Cardiology

    Jose A. Rodriguez

  65. Influence of the 4G/5G PAI-1 genotype on angiotensin II-stimulated human endothelial cells and in patients with hypertension

    Article • Cardiovascular Research, July 2004, European Society of Cardiology

    Jose A. Rodriguez

  66. Vitamins C and E downregulate vascular VEGF and VEGFR-2 expression in apolipoprotein-E-deficient mice

    Article • Atherosclerosis, November 2003, Elsevier

    Jose A. Rodriguez

  67. Different expression of MMPs/TIMP-1 in human atherosclerotic lesions. Relation to plaque features and vascular bed

    Article • Atherosclerosis, October 2003, Elsevier

    Jose A. Rodriguez

  68. Antioxidant vitamins increase the collagen content and reduce MMP-1 in a porcine model of atherosclerosis: implications for plaque stabilization

    Article • Atherosclerosis, March 2003, Elsevier

    Jose A. Rodriguez

  69. Estabilización de la placa de ateroma: un nuevo concepto basado en la biología dinámica de la aterosclerosis

    Article • Medicina Clínica, January 2003, Elsevier

    Jose A. Rodriguez

  70. Dietary supplementation with vitamins C and E prevents downregulation of endothelial NOS expression in hypercholesterolemia in vivo and in vitro

    Article • Atherosclerosis, November 2002, Elsevier

    Jose A. Rodriguez

  71. Hyperhomocysteinemia in Liver Cirrhosis: Mechanisms and Role in Vascular and Hepatic Fibrosis

    Article • Hypertension, November 2001, Wolters Kluwer Health

    Jose A. Rodriguez

  72. Vitamins C and E attenuate plasminogen activator inhibitor-1 (PAI-1) expression in a hypercholesterolemic porcine model of angioplasty

    Article • Cardiovascular Research, February 2001, European Society of Cardiology

    Jose A. Rodriguez

  73. Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, September 1999, Elsevier

    Jose A. Rodriguez

  74. Torasemide Inhibits Angiotensin II Induced Vasoconstriction and Intracellular Calcium Increase in the Aorta of Spontaneously Hypertensive Rats

    Article • Hypertension, July 1999, Wolters Kluwer Health

    Jose A. Rodriguez

  75. Cloning of Rat and Human Inducible Penile Nitric Oxide Synthase. Application for Gene Therapy of Erectile Dysfunction1

    Article • Biology of Reproduction, April 1997, Oxford University Press (OUP)

    Jose A. Rodriguez

  76. Cloning of a Novel Neuronal Nitric Oxide Synthase Expressed in Penis and Lower Urinary Tract

    Article • Biochemical and Biophysical Research Communications, September 1996, Elsevier

    Jose A. Rodriguez

  77. Up-regulation of the levels of androgen receptor and its mRNA by androgens in smooth-muscle cells from rat penis

    Article • Molecular and Cellular Endocrinology, January 1993, Elsevier

    Jose A. Rodriguez