All Stories

  1. Distinct Responses to IL4 in Macrophages Mediated by JNK

    Article • Cells, April 2023, MDPI AG

    Jorge Lloberas

  2. IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages

    Article • Journal of Innate Immunity, November 2022, Karger Publishers

    Jorge Lloberas

  3. GM-CSF Protects Macrophages from DNA Damage by Inducing Differentiation

    Article • Cells, March 2022, MDPI AG

    Jorge Lloberas

  4. Induction of CIITA by IFN-γ in macrophages involves STAT1 activation by JAK and JNK

    Article • Immunobiology, September 2021, Elsevier

    Jorge Lloberas

  5. Macrophage mitochondrial MFN2 (mitofusin 2) links immune stress and immune response through reactive oxygen species (ROS) production

    Article • Autophagy, November 2020, Taylor & Francis

    Jorge Lloberas

  6. Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity

    Article • Cell Reports, August 2020, Elsevier

    Jorge Lloberas

  7. Induction of Samhd1 by interferon gamma and lipopolysaccharide in murine macrophages requires IRF1

    Article • European Journal of Immunology, May 2020, Wiley

    Jorge Lloberas

  8. Macrophages and Mitochondria

    Article • January 2017, Elsevier

    Jorge Lloberas

  9. Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology

    Article • Frontiers in Molecular Biosciences, June 2016, Frontiers

    Jorge Lloberas

  10. NBS1 is required for macrophage homeostasis and functional activity in mice

    Article • Blood, November 2015, American Society of Hematology

    Jorge Lloberas

  11. The Response of Secondary Genes to Lipopolysaccharides in Macrophages Depends on Histone Deacetylase and Phosphorylation of C/EBPβ

    Article • The Journal of Immunology, January 2014, The American Association of Immunologists

    Jorge Lloberas

  12. The Exonuclease Trex1 Restrains Macrophage Proinflammatory Activation

    Article • The Journal of Immunology, December 2013, The American Association of Immunologists

    Jorge Lloberas

  13. Arginine Transport Is Impaired in C57Bl/6 Mouse Macrophages as a Result of a Deletion in the Promoter of Slc7a2 (CAT2), and Susceptibility to Leishmania Infection Is Reduced

    Article • The Journal of Infectious Diseases, March 2013, Oxford University Press (OUP)

    Jorge Lloberas

  14. Deacetylation of C/EBPβ is required for IL-4-inducedarginase-1expression in murine macrophages

    Article • European Journal of Immunology, September 2012, Wiley

    Jorge Lloberas

  15. MKP-1: A critical phosphatase in the biology of macrophages controlling the switch between proliferation and activation

    Article • European Journal of Immunology, August 2012, Wiley

    Jorge Lloberas

  16. Inorganic nanoparticles and the immune system: detection, selective activation and tolerance

    Article • February 2012, SPIE

    Jorge Lloberas

  17. Arginine and Macrophage Activation

    Article • December 2011, Springer Science + Business Media

    Jorge Lloberas

  18. Characterization of Trex1 Induction by IFN-γ in Murine Macrophages

    Article • The Journal of Immunology, February 2011, The American Association of Immunologists

    Jorge Lloberas

  19. Macrophage Proinflammatory Activation and Deactivation

    Article • January 2010, Elsevier

    Jorge Lloberas

  20. The locus control region of the MHC class II promoter acts as a repressor element, the activity of which is inhibited by CIITA

    Article • Molecular Immunology, January 2010, Elsevier

    Jorge Lloberas

  21. Telomere Shortening and Oxidative Stress in Aged Macrophages Results in Impaired STAT5a Phosphorylation

    Article • The Journal of Immunology, August 2009, The American Association of Immunologists

    Jorge Lloberas

  22. CREB and AP-1 activation regulates MKP-1 induction by LPS or M-CSF and their kinetics correlate with macrophage activationversusproliferation

    Article • European Journal of Immunology, July 2009, Wiley

    Jorge Lloberas

  23. Homogeneous Conjugation of Peptides onto Gold Nanoparticles Enhances Macrophage Response

    Article • ACS Nano, June 2009, American Chemical Society (ACS)

    Jorge Lloberas

  24. p21waf1/CIP1, a CDK inhibitor and a negative feedback system that controls macrophage activation

    Article • European Journal of Immunology, March 2009, Wiley

    Jorge Lloberas

  25. Peptides conjugated to gold nanoparticles induce macrophage activation

    Article • Molecular Immunology, February 2009, Elsevier

    Jorge Lloberas

  26. IL-4 blocks M-CSF-dependent macrophage proliferation by inducing p21Waf1 in a STAT6-dependent way

    Article • European Journal of Immunology, January 2009, Wiley

    Jorge Lloberas

  27. Macrophage Activation: Classical Vs. Alternative

    Article • January 2009, Springer Science + Business Media

    Jorge Lloberas

  28. Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases

    Article • Protein Science, December 2008, Wiley

    Jorge Lloberas

  29. Granulocyte Macrophage-Colony-Stimulating Factor-Dependent Proliferation Is Impaired in Macrophages From Senescence-Accelerated Mice

    Article • The Journals of Gerontology Series A, November 2008, Oxford University Press (OUP)

    Jorge Lloberas

  30. IFN-γ–mediated inhibition of MAPK phosphatase expression results in prolonged MAPK activity in response to M-CSF and inhibition of proliferation

    Article • Blood, October 2008, American Society of Hematology

    Jorge Lloberas

  31. Deacetylase Activity Is Required for STAT5-Dependent GM-CSF Functional Activity in Macrophages and Differentiation to Dendritic Cells

    Article • The Journal of Immunology, May 2008, The American Association of Immunologists

    Jorge Lloberas

  32. Lipopolysaccharide Up-Regulates MHC Class II Expression on Dendritic Cells through an AP-1 Enhancer without Affecting the Levels of CIITA

    Article • The Journal of Immunology, May 2007, The American Association of Immunologists

    Jorge Lloberas

  33. Structure of the Dimeric Exonuclease TREX1 in Complex with DNA Displays a Proline-rich Binding Site for WW Domains

    Article • Journal of Biological Chemistry, May 2007, Elsevier

    Jorge Lloberas

  34. JNK1 Is Required for the Induction of Mkp1 Expression in Macrophages during Proliferation and Lipopolysaccharide-dependent Activation

    Article • Journal of Biological Chemistry, April 2007, Elsevier

    Jorge Lloberas

  35. Cyclophilin A is required for M-CSF-dependent macrophage proliferation

    Article • European Journal of Immunology, September 2006, Wiley

    Jorge Lloberas

  36. Macrophages require distinct arginine catabolism and transport systems for proliferation and for activation

    Article • European Journal of Immunology, June 2006, Wiley

    Jorge Lloberas

  37. Macrophage-Colony-Stimulating Factor-Induced Proliferation and Lipopolysaccharide-Dependent Activation of Macrophages Requires Raf-1 Phosphorylation to Induce Mitogen Kinase Phosphatase-1 Expression

    Article • The Journal of Immunology, June 2006, The American Association of Immunologists

    Jorge Lloberas

  38. Arginine Transport via Cationic Amino Acid Transporter 2 Plays a Critical Regulatory Role in Classical or Alternative Activation of Macrophages

    Article • The Journal of Immunology, May 2006, The American Association of Immunologists

    Jorge Lloberas

  39. MacrophAging: A cellular and molecular review

    Article • Immunobiology, August 2005, Elsevier

    Jorge Lloberas

  40. Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors

    Article • International Journal of Cancer, January 2004, Wiley

    Jorge Lloberas

  41. Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1

    Article • Genes & Immunity, January 2004, Springer Science + Business Media

    Jorge Lloberas

  42. Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism

    Article • Journal of Biological Chemistry, May 2003, Elsevier

    Jorge Lloberas

  43. Effect of aging on macrophage function

    Article • Experimental Gerontology, December 2002, Elsevier

    Jorge Lloberas

  44. Immunosenescence of macrophages: reduced MHC class II gene expression

    Article • Experimental Gerontology, January 2002, Elsevier

    Jorge Lloberas

  45. From transcription to cell surface expression, the induction of MHC class II I-Aα by interferon-γ in macrophages is regulated at different levels

    Article • Immunogenetics, March 2001, Springer Science + Business Media

    Jorge Lloberas

  46. An Orf FromBacillus licheniformisEncodes A Putative DNA Repressor

    Article • DNA Sequence, January 2000, Taylor & Francis

    Jorge Lloberas

  47. Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (bo,+AT) of rBAT

    Article • Nature Genetics, September 1999, Springer Science + Business Media

    Jorge Lloberas

  48. Identification of a Membrane Protein, LAT-2, That Co-expresses with 4F2 Heavy Chain, an L-type Amino Acid Transport Activity with Broad Specificity for Small and Large Zwitterionic Amino Acids

    Article • Journal of Biological Chemistry, July 1999, Elsevier

    Jorge Lloberas

  49. Interferon γ Induces the Expression of p21waf-1 and Arrests Macrophage Cell Cycle, Preventing Induction of Apoptosis

    Article • Immunity, July 1999, Elsevier

    Jorge Lloberas

  50. The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages

    Article • Immunology Today, April 1999, Elsevier

    Jorge Lloberas

  51. Identification and Characterization of a Membrane Protein (y+L Amino Acid Transporter-1) That Associates with 4F2hc to Encode the Amino Acid Transport Activity y+L

    Article • Journal of Biological Chemistry, December 1998, Elsevier

    Jorge Lloberas

  52. Two Missense Point Mutations in Different Alleles in the 3-Hydroxy-3-methylglutaryl Coenzyme A Lyase Gene Produce 3-Hydroxy-3-methylglutaric Aciduria in a French Patient

    Article • Archives of Biochemistry and Biophysics, October 1998, Elsevier

    Jorge Lloberas

  53. Dexamethasone enhances macrophage colony stimulating factor- and granulocyte macrophage colony stimulating factor-stimulated proliferation of bone marrow-derived macrophages

    Article • International Immunology, May 1998, Oxford University Press (OUP)

    Jorge Lloberas

  54. Glycoprotein E of bovine herpesvirus type 1 is involved in virus transmission by direct cell-to-cell spread

    Article • Virus Research, November 1996, Elsevier

    Jorge Lloberas

  55. The transcription factor PU.1 is involved in macrophage proliferation.

    Article • The Journal of Experimental Medicine, July 1996, Rockefeller University Press

    Jorge Lloberas

  56. Repression of I-Aβ Gene Expression by the Transcription Factor PU.1

    Article • Journal of Biological Chemistry, October 1995, Elsevier

    Jorge Lloberas

  57. A beta-glucosidase gene (bgl3) from Streptomyces sp. strain QM-B814. Molecular cloning, nucleotide sequence, purification and characterization of the encoded enzyme, a new member of family 1 glycosyl hydrolases

    Article • European Journal of Biochemistry, July 1994, Wiley

    Jorge Lloberas

  58. Molecular cloning, expression and nucleotide sequence of the endo-beta-1,3-1,4-d-glucanase gene from Bacillus licheniformis Predictive structural analyses of the encoded polypeptide

    Article • European Journal of Biochemistry, April 1991, Wiley

    Jorge Lloberas

  59. Purification and characterization of endo-?-1,3-1,4-d-glucanase activity from Bacillus licheniformis

    Article • Applied Microbiology and Biotechnology, August 1988, Springer Science + Business Media

    Dr Jordi Bernués, Jorge Lloberas