All Stories

  1. LC–MS-Based Direct Quantification of MicroRNAs in Rat Blood

    Article • ACS Omega, October 2023, American Chemical Society (ACS)

    Jonh-Hwa Lee

  2. Particulate Matter Elevates Ocular Inflammation and Endoplasmic Reticulum Stress in Human Retinal Pigmented Epithelium Cells

    Article • International Journal of Environmental Research and Public Health, March 2023, MDPI AG

    Jonh-Hwa Lee

  3. Ellagic Acid Prevents Particulate Matter-Induced Pulmonary Inflammation and Hyperactivity in Mice: A Pilot Study

    Article • International Journal of Environmental Research and Public Health, March 2023, MDPI AG

    Jonh-Hwa Lee

  4. Quantification of venadaparib, a novel PARP inhibitor, in the rat and dog plasma using liquid chromatography/tandem mass spectrometry

    Article • Journal of Analytical Science & Technology, February 2023, Springer Science + Business Media

    Jonh-Hwa Lee

  5. Dietary Intervention with Quercetin Attenuates Diesel Exhaust Particle-Instilled Pulmonary Inflammation and Behavioral Abnormalities in Mice

    Article • Journal of Medicinal Food, January 2023, Mary Ann Liebert Inc

    Jonh-Hwa Lee

  6. Probiotic, Paraprobiotic, and Hydrolyzed Yeast Mixture Supplementation Has Comparable Effects to Zinc Oxide in Improving Growth Performance and Ameliorating Post-weaning Diarrhea in Weaned Piglets

    Article • Probiotics and Antimicrobial Proteins, January 2023, Springer Science + Business Media

    Jonh-Hwa Lee

  7. Application of physiologically‐based pharmacokinetic model approach to predict pharmacokinetics and drug–drug interaction of rivaroxaban: A case study of rivaroxaban and carbamazepine

    Article • CPT Pharmacometrics & Systems Pharmacology, October 2022, Wiley

    Jonh-Hwa Lee

  8. Formulation Approaches for Improving the Dissolution Behavior and Bioavailability of Tolvaptan Using SMEDDS

    Article • Pharmaceutics, February 2022, MDPI AG

    Jonh-Hwa Lee

  9. The Development and Optimization of Hot-Melt Extruded Amorphous Solid Dispersions Containing Rivaroxaban in Combination with Polymers

    Article • Pharmaceutics, March 2021, MDPI AG

    Jonh-Hwa Lee

  10. Simultaneous Quantification of 3′- and 6′-Sialyllactose in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Pharmacokinetic Study

    Article • Molecules, February 2021, MDPI AG

    Jonh-Hwa Lee

  11. Development and validation of a bioanalytical method of analyzing 3′- and 6′-sialyllactose using liquid chromatography–tandem mass spectrometry in minipig plasma and its application in a pharmacokinetic study

    Article • Journal of Pharmaceutical and Biomedical Analysis, February 2021, Elsevier

    Jonh-Hwa Lee

  12. Quantification of triiodothyronine and thyroxine in rat serum using liquid chromatography tandem mass spectrometry

    Article • Journal of Pharmaceutical and Biomedical Analysis, February 2021, Elsevier

    Jonh-Hwa Lee

  13. An Exploratory Study of the Relationships Between Diesel Engine Exhaust Particle Inhalation, Pulmonary Inflammation and Anxious Behavior

    Article • International Journal of Environmental Research and Public Health, January 2021, MDPI AG

    Jonh-Hwa Lee

  14. Gender differences and dose proportionality in the toxicokinetics of udenafil and its active metabolite following oral administration in rodents

    Article • Toxicology and Applied Pharmacology, January 2021, Elsevier

    Jonh-Hwa Lee

  15. Development and Validation of a Bioanalytical Method for 3′- and 6′-Sialyllactose in Minipig Liver and Kidney Using Liquid Chromatography-Tandem Mass Spectrometry and Its Application to Analysis of Tissue Distribution

    Article • Molecules, December 2020, MDPI AG

    Jonh-Hwa Lee

  16. Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted Cancer

    Article • Cancers, June 2020, MDPI AG

    young kee shin, Jonh-Hwa Lee

  17. Determination of motolimod concentration in rat plasma by liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study

    Article • Journal of Pharmaceutical and Biomedical Analysis, February 2020, Elsevier

    Jonh-Hwa Lee

  18. Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry

    Article • Molecules, January 2020, MDPI AG

    Jonh-Hwa Lee

  19. Development and Evaluation of Raloxifene-Hydrochloride-Loaded Supersaturatable SMEDDS Containing an Acidifier

    Article • Pharmaceutics, June 2018, MDPI AG

    Jonh-Hwa Lee

  20. Identification of metabolites of MDR-1339, an inhibitor of β-amyloid protein aggregation, and kinetic characterization of the major metabolites in rats

    Article • Journal of Pharmaceutical and Biomedical Analysis, March 2018, Elsevier

    Jonh-Hwa Lee

  21. Development of a LC–MS/MS method for the determination of CKD-712 in rat plasma: Application to a pharmacokinetic study in rats

    Article • Journal of Chromatography B, September 2017, Elsevier

    Jonh-Hwa Lee

  22. Simultaneous quantification of volitinib and gefitinib in rat plasma by HPLC-MS/MS for application to a pharmacokinetic study in rats

    Article • Journal of Separation Science, August 2017, Wiley

    Jonh-Hwa Lee

  23. Quantification of EC-18, a synthetic monoacetyldiglyceride (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), in rat and mouse plasma by liquid-chromatography/tandem mass spectrometry

    Article • Journal of Pharmaceutical and Biomedical Analysis, April 2017, Elsevier

    Jonh-Hwa Lee

  24. Development and validation of a liquid chromatography–tandem mass spectrometry method for the assay of tafamidis in rat plasma: Application to a pharmacokinetic study in rats

    Article • Journal of Pharmaceutical and Biomedical Analysis, April 2017, Elsevier

    Jonh-Hwa Lee

  25. Specific Inhibition of the Distribution of Lobeglitazone to the Liver by Atorvastatin in Rats: Evidence for a Rat Organic Anion Transporting Polypeptide 1B2–Mediated Interaction in Hepatic Transport

    Article • Drug Metabolism and Disposition, March 2017, Elsevier

    Jonh-Hwa Lee

  26. Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T/C in the mouse liver

    Article • European Journal of Pharmaceutical Sciences, January 2017, Elsevier

    Jonh-Hwa Lee

  27. Subacute toxicity evaluation of KR-33493, FAF1 inhibitor for a new anti-parkinson's disease agent, after oral administration in rats and dogs

    Article • Regulatory Toxicology and Pharmacology, November 2016, Elsevier

    Jonh-Hwa Lee

  28. The identification of lobeglitazone metabolites in rat liver microsomes and the kinetics of the in vivo formation of the major metabolite M1 in rats

    Article • Journal of Pharmaceutical and Biomedical Analysis, November 2015, Elsevier

    Jonh-Hwa Lee

  29. A novel HPLC–MS/MS method for the simultaneous determination of astemizole and its major metabolite in dog or monkey plasma and application to pharmacokinetics

    Article • Journal of Pharmaceutical and Biomedical Analysis, October 2015, Elsevier

    Jonh-Hwa Lee

  30. Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats

    Article • Journal of Pharmaceutical Sciences, September 2015, Elsevier

    jong-hwa lee, Jonh-Hwa Lee

  31. Gender differences in the hepatic elimination and pharmacokinetics of lobeglitazone in rats

    Article • Biopharmaceutics & Drug Disposition, May 2015, Wiley

    jong-hwa lee, Jonh-Hwa Lee

  32. Development of QTc prolongation model incorporating circadian rhythm using harmonic model

    Article • Xenobiotica, December 2014, Taylor & Francis

    Jonh-Hwa Lee

  33. QUANTIFICATION OF ZABOFLOXACIN IN RAT PLASMA USING HPLC-UV DETECTOR AND ITS APPLICATION TO A PHARMACOKINETIC STUDY

    Article • Journal of Liquid Chromatography &amp Related Technologies, November 2013, Taylor & Francis

    Jonh-Hwa Lee

  34. Embryotoxicity and Toxicokinetics of the Antimalarial Artesunate in Rats

    Article • Toxicological Research, March 2013, The Korean Society of Toxicology

    Jonh-Hwa Lee

  35. Milk Transfer and Toxicokinetics of Valproic Acid in Lactating Cynomolgus Monkeys

    Article • Toxicological Research, March 2013, The Korean Society of Toxicology

    Jonh-Hwa Lee

  36. 1′-Acetoxychavicol Acetate Isolated from Alpinia galanga Ameliorates Ovalbumin-Induced Asthma in Mice

    Article • PLOS One, February 2013, PLOS

    Jonh-Hwa Lee

  37. Self-microemulsifying drug-delivery system for improved oral bioavailability of pranlukast hemihydrate: preparation and evaluation

    Article • International Journal of Nanomedicine, January 2013, Taylor & Francis

    jong-hwa lee, Jonh-Hwa Lee

  38. Development of a LC–MS method for quantification of FK-3000 and its application to in vivo pharmacokinetic study in drug development

    Article • Journal of Pharmaceutical and Biomedical Analysis, November 2012, Elsevier

    Jonh-Hwa Lee

  39. The Zanthoxylum schinifolium seed oil modulates immune function under the biological safety level

    Article • Molecular & Cellular Toxicology, June 2012, Springer Science + Business Media

    Jonh-Hwa Lee

  40. QUANTIFICATION OF CILNIDIPINE IN HUMAN PLASMA BY LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY

    Article • Journal of Liquid Chromatography &amp Related Technologies, January 2012, Taylor & Francis

    Jonh-Hwa Lee

  41. Quantification of oltipraz using liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study in rat plasma

    Article • Journal of Pharmaceutical and Biomedical Analysis, November 2011, Elsevier

    Jonh-Hwa Lee

  42. Stephania delavayi Diels. inhibits breast carcinoma proliferation through the p38 MAPK/NF-κB/COX-2 pathway

    Article • Oncology Reports, June 2011, Spandidos Publications

    Jonh-Hwa Lee

  43. Biological safety and B cells activation effects of Zanthoxylum schinifolium

    Article • Molecular & Cellular Toxicology, June 2011, Springer Science + Business Media

    Jonh-Hwa Lee

  44. Quantitative determination of sirolimus in dog blood using liquid chromatography–tandem mass spectrometry, and its applications to pharmacokinetic studies

    Article • Journal of Pharmaceutical and Biomedical Analysis, December 2010, Elsevier

    Jonh-Hwa Lee

  45. The stoichiometric relationship between KCNH-2 and KCNE-2 in IKr channel formation

    Article • International Journal of Cardiology, November 2010, Elsevier

    Jonh-Hwa Lee

  46. Simultaneous gene expression signature of heart and peripheral blood mononuclear cells in astemizole-treated rats

    Article • Archives of Toxicology, March 2010, Springer Science + Business Media

    Jonh-Hwa Lee

  47. Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its applications to pharmacokinetic studies

    Article • Journal of Pharmaceutical and Biomedical Analysis, December 2009, Elsevier

    jong-hwa lee, Jonh-Hwa Lee

  48. Determination of Belotecan in the Plasma, Bile, and Urine of Rats by High-Performance Liquid Chromatography with Fluorescence Detection and Its Application to a Pharmacokinetic Study

    Article • Analytical Letters, January 2009, Taylor & Francis

    Jonh-Hwa Lee

  49. Assessment of General and Cardiac Toxicities of Astemizole in Male Cynomolgus Monkeys: Serum Biochemistry and Action Potential Duration

    Article • Toxicological Research, December 2008, The Korean Society of Toxicology

    Jonh-Hwa Lee

  50. Reliable and fast quantitative analysis of active ingredient in pharmaceutical suspension using Raman spectroscopy

    Article • Analytica Chimica Acta, June 2007, Elsevier

    Jonh-Hwa Lee, Dr Seok Chan Park