Dr Jonathan Malcolm Friedman
Post-Doc, Biological Sciences
Japan
My co-authors include
Dr Oluwatoyin A Asojo
My Publications
CBS9106-Induced CRM1 Degradation Is Mediated by Cullin Ring Ligase Activity and the Ned...
Molecular Cancer Therapeutics
September 2014
CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity
Blood
August 2011
Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a ...
Molecular Cancer Therapeutics
January 2007
Crystal Structures of KDOP Synthase in Its Binary Complexes with the Substrate Phosphoe...
Biochemistry
May 2001
Interconversion between 3D molecular representations: some macromolecular applications ...
Computers & Chemistry
January 1999
Regio- and Diastereoselective Michael Additions by Unsymmetrical Allylic Anions Upon Et...
Synthetic Communications
September 1997
Fourier-filtered van der Waals contact surfaces: accurate ligand shapes from protein st...
Protein Engineering Design and Selection
August 1997
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transc...
Proceedings of the National Academy of Sciences
July 1994
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase...
Proceedings of the National Academy of Sciences
April 1994
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucle...
Biochemistry
December 1993
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an ...
Science
June 1992
Holding on and letting go
Current Biology
June 1992
Cocrystal structure of an editing complex of Klenow fragment with DNA.
Proceedings of the National Academy of Sciences
December 1988
Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I
Science
April 1988
The quest for free metaphosphate in solution. Racemization at phosphorus in the transfe...
Journal of the American Chemical Society
February 1988
Free monomeric metaphosphate in protic solution: complete racemization at phosphorus in...
Journal of the American Chemical Society
May 1987
The quest for free metaphosphate in solution: racemization at phosphorus in the transfe...
Journal of the American Chemical Society
October 1985
Stereochemistry of nucleophilic displacement on two phosphoric monoesters and a phospho...
Journal of the American Chemical Society
August 1984
Characterization of short-chain alkyl ether lecithin analogs: carbon-13 NMR and phospho...
Biochemistry
October 1981