All Stories

  1. Exploring Meiosis in Brown Algae: Meiotic Axis Proteins in the model brown algaEctocarpus

    Article • December 2024, Cold Spring Harbor Laboratory Press

    John Weir

  2. Kinetic and structure-based comparisons of silent and stimulatory flagellin interactions with TLR5

    Article • December 2024, Cold Spring Harbor Laboratory Press

    John Weir

  3. Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes

    Article • Nature Communications, April 2024, Springer Science + Business Media

    John Weir

  4. The molecular machinery of meiotic recombination

    Article • Biochemical Society Transactions, February 2024, Portland Press Ltd.

    John Weir

  5. Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes

    Article • November 2023, Cold Spring Harbor Laboratory Press

    John Weir

  6. Molekulare Mechanismen der meiotischen Rekombination

    Article • BIOspektrum, November 2023, Springer Science + Business Media

    John Weir

  7. kcnj13regulates pigment cell shapes in zebrafish and has diverged by cis-regulatory evolution betweenDaniospecies

    Article • Development, August 2023, The Company of Biologists

    John Weir

  8. Biochemical characterisation of Mer3 helicase interactions and the protection of meiotic recombination intermediates

    Article • Nucleic Acids Research, March 2023, Oxford University Press (OUP)

    John Weir

  9. Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5

    Article • Science Immunology, January 2023, American Association for the Advancement of Science

    John Weir

  10. Unwinding during stressful times: Mechanisms of helicases in meiotic recombination

    Article • January 2023, Elsevier

    John Weir

  11. Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin

    Article • PLoS Genetics, December 2022, PLOS

    John Weir

  12. Cis-regulatory evolution of the potassium channel genekcnj13during pigment pattern diversification inDaniofish

    Article • December 2022, Cold Spring Harbor Laboratory Press

    John Weir

  13. Mer3 helicase protects early crossover intermediates from STR complex disassembly during meiosis

    Article • June 2022, Cold Spring Harbor Laboratory Press

    John Weir

  14. Studying meiosis in mitosis: Activating the meiosis-specific Red1-Hop1-Mek1 complex in mitotic budding yeast cells

    Article • April 2022, Cold Spring Harbor Laboratory Press

    John Weir

  15. Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation

    Article • eLife, December 2021, eLife

    John Weir

  16. InteBac: An integrated bacterial and baculovirus expression vector suite

    Article • Protein Science, October 2020, Wiley

    John Weir

  17. Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly

    Article • Life Science Alliance, August 2020, Life Science Alliance, LLC

    John Weir

  18. Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation

    Article • July 2020, Cold Spring Harbor Laboratory Press

    John Weir

  19. InteBac - An integrated bacterial and baculovirus expression vector suite

    Article • July 2020, Cold Spring Harbor Laboratory Press

    John Weir

  20. A meiosis-specific AAA+ assembly reveals repurposing of ORC during budding yeast gametogenesis

    Article • April 2019, Cold Spring Harbor Laboratory Press

    John Weir

  21. Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

    Article • Molecular Cell, September 2018, Elsevier

    John Weir

  22. Decoding the centromeric nucleosome through CENP-N

    Article • eLife, December 2017, eLife

    John Weir

  23. Insights from biochemical reconstitution into the architecture of human kinetochores

    Article • Nature, August 2016, Springer Science + Business Media

    John Weir

  24. Progress in the structural and functional characterization of kinetochores

    Article • Current Opinion in Structural Biology, April 2016, Elsevier

    John Weir

  25. Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1

    Article • PLOS One, December 2015, PLOS

    John Weir

  26. CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores

    Article • Journal of Cell Biology, June 2015, Rockefeller University Press

    John Weir

  27. The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities

    Article • Molecular Cell, September 2014, Elsevier

    John Weir, John Weir

  28. The pseudo GTPase CENP-M drives human kinetochore assembly

    Article • eLife, July 2014, eLife

    John Weir, Andrea Musacchio, Anna De Antoni, Dr Ana M Rojas, Dr Federica Basilico, Dr Stefano Maffini, John Weir

  29. Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling

    Article • eLife, September 2013, eLife

    John Weir, Andrea Musacchio, John Weir

  30. Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance

    Article • Proceedings of the National Academy of Sciences, June 2010, Proceedings of the National Academy of Sciences

    John Weir, John Weir

  31. The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

    Article • Science, October 2009, American Association for the Advancement of Science

    John Weir, John Weir

  32. GTPase activation of elongation factor EF-Tu by the ribosome during decoding

    Article • The EMBO Journal, February 2009, Wiley

    John Weir, John Weir

  33. Structure of the 70 S Ribosome Complexed with mRNA and tRNA

    Article • Science, September 2006, American Association for the Advancement of Science

    John Weir

  34. Finishing the euchromatic sequence of the human genome

    Article • Nature, October 2004, Springer Science + Business Media

    John Weir

  35. Abstract

    Article • eLife

    John Weir