All Stories

  1. Small caliber arterial endothelial cells calcium signals elicited by PAR 2 are preserved from endothelial dysfunction

    Article • Pharmacology Research & Perspectives, February 2015, Wiley

    Dr John J McGuire

  2. Disturbance of vasodilation via protease-activated receptor 2 in SHRSP.Z-Leprfa/IzmDmcr rats with metabolic syndrome

    Article • Vascular Pharmacology, October 2014, Elsevier

    Dr John J McGuire

  3. Effects of chronic in-vivo treatments with protease-activated receptor 2 agonist on endothelium function and blood pressures in mice

    Article • Canadian Journal of Physiology and Pharmacology, April 2013, Canadian Science Publishing

    Dr John J McGuire

  4. Attenuated Vasodilator Effectiveness of Protease-Activated Receptor 2 Agonist in Heterozygous par2 Knockout Mice

    Article • PLoS ONE, February 2013, PLOS

    Dr John J McGuire

  5. Preserved arterial vasodilatation via endothelial protease-activated receptor-2 in obese type 2 diabetic mice

    Article • British Journal of Pharmacology, August 2011, Wiley

    Dr John J McGuire

  6. Protection of protease-activated receptor 2 mediated vasodilatation against angiotensin II-induced vascular dysfunction in mice

    Article • BMC Pharmacology, January 2011, Springer Science + Business Media

    Dr John J McGuire

  7. Protease-activated receptor 2 and bradykinin-mediated vasodilation in the cerebral arteries of stroke-prone rats

    Article • Peptides, February 2010, Elsevier

    Dr John J McGuire

  8. Corrigendum

    Article • AJP Regulatory Integrative and Comparative Physiology, August 2009, American Physiological Society

    Dr John J McGuire

  9. Developmental programming of lipid metabolism and aortic vascular function in C57BL/6 mice: a novel study suggesting an involvement of LDL-receptor

    Article • AJP Regulatory Integrative and Comparative Physiology, February 2009, American Physiological Society

    Dr John J McGuire

  10. Blood pressures, heart rate and locomotor activity during salt loading and angiotensin II infusion in protease-activated receptor 2 (PAR2) knockout mice

    Article • BMC Physiology, January 2008, Springer Science + Business Media

    Dr John J McGuire

  11. Effects of Poststroke Losartan Versus Captopril Treatment on Myogenic and Endothelial Function in the Cerebrovasculature of SHRsp

    Article • Stroke, March 2007, Wolters Kluwer Health

    Dr John J McGuire

  12. Persistence of PAR-2 vasodilation despite endothelial dysfunction in BPH/2 hypertensive mice

    Article • Pflügers Archiv - European Journal of Physiology, February 2007, Springer Science + Business Media

    Dr John J McGuire

  13. PHENOTYPING THE LEVEL OF BLOOD PRESSURE BY TELEMETRY IN MICE

    Article • Clinical and Experimental Pharmacology and Physiology, November 2006, Wiley

    Dr John J McGuire

  14. Hyperpolarization of murine small caliber mesenteric arteries by activation of endothelial proteinase-activated receptor 2

    Article • Canadian Journal of Physiology and Pharmacology, December 2004, Canadian Science Publishing

    Dr John J McGuire

  15. Proteinase-Activated Receptor 2 (PAR2): A Challenging New Target for Treatment of Vascular Diseases

    Article • Current Pharmaceutical Design, August 2004, Bentham Science Publishers

    Dr John J McGuire

  16. 2-Furoyl-LIGRLO-amide: A Potent and Selective Proteinase-Activated Receptor 2 Agonist

    Article • Journal of Pharmacology and Experimental Therapeutics, February 2004, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr John J McGuire

  17. Searching for the physiological role and therapeutic potential of vascular proteinase-activated receptor-2 (PAR2)

    Article • Drug Development Research, September 2003, Wiley

    Dr John J McGuire

  18. A photosensitive vascular smooth muscle store of nitric oxide in mouse aorta: no dependence on expression of endothelial nitric oxide synthase

    Article • British Journal of Pharmacology, March 2003, Wiley

    Dr John J McGuire

  19. The Endothelium in Health and Disease -A Target for Therapeutic Intervention

    Article • Journal of Smooth Muscle Research, January 2003, Japan Society of Smooth Muscle Research

    Dr John J McGuire

  20. Proteinase-Activated Receptor-2 (PAR2): Vascular Effects of a PAR2-Derived Activating Peptide via a Receptor Different than PAR2

    Article • Journal of Pharmacology and Experimental Therapeutics, December 2002, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr John J McGuire

  21. Restricted ability of human mast cell tryptase to activate proteinase-activated receptor-2 in rat aorta

    Article • Canadian Journal of Physiology and Pharmacology, October 2002, Canadian Science Publishing

    Dr John J McGuire

  22. Endothelium-derived relaxing factors: A focus on endothelium-derived hyperpolarizing factor(s)

    Article • Canadian Journal of Physiology and Pharmacology, January 2001, Canadian Science Publishing

    Dr John J McGuire

  23. Enantioselective inhibition of the biotransformation and pharmacological actions of isoidide dinitrate by diphenyleneiodonium sulphate

    Article • British Journal of Pharmacology, January 1999, Wiley

    Dr John J McGuire

  24. Inhibition of NADPH-cytochrome P450 reductase and glyceryl trinitrate biotransformation by diphenyleneiodonium sulfate

    Article • Biochemical Pharmacology, October 1998, Elsevier

    Dr John J McGuire