All Stories

  1. Facilitating data collaboration for precision medicine.

    Article • PLOS Digital Health, January 2025, PLOS

    Dr. John Jacobs

  2. A data management system for precision medicine

    Article • February 2024, Cold Spring Harbor Laboratory Press

    Dr. John Jacobs

  3. Trust in and Acceptance of Artificial Intelligence Applications in Medicine: Mixed Methods Study

    Article • JMIR Human Factors, January 2024, JMIR Publications Inc.

    Dr. John Jacobs, Dr Bert Vrijhoef

  4. Precision Medicine for More Oxygen (P4O2)—Study Design and First Results of the Long COVID-19 Extension

    Article • Journal of Personalized Medicine, June 2023, MDPI AG

    Dr. John Jacobs

  5. Trust in and Acceptance of Artificial Intelligence Applications in Medicine: Mixed Methods Study (Preprint)

    Article • March 2023, JMIR Publications Inc.

    Dr. John Jacobs, Dr Bert Vrijhoef

  6. Neutralizing antibodies mediate virus-immune pathology of COVID-19

    Article • Medical Hypotheses, October 2020, Elsevier

    Dr. John Jacobs

  7. A computerised decision support system for cardiovascular risk management ‘live’ in the electronic health record environment: development, validation and implementation—the Utrecht Cardiovascular Cohort Initiative

    Article • Netherlands Heart Journal, August 2019, Springer Science + Business Media

    Dr. John Jacobs

  8. Serum testosterone plays an important role in the metastatic ability of castration resistant prostate cancer

    Article • World Journal of Urology, October 2012, Springer Science + Business Media

    Dr. John Jacobs

  9. “First do no harm” and the importance of prediction in oncology

    Article • The EPMA Journal, July 2010, Springer Science + Business Media

    Dr. John Jacobs

  10. The Amiens Strategy: Small Phase III Trials for Clinically Relevant Progress in the War Against Cancer

    Article • Journal of Clinical Oncology, June 2009, American Society of Clinical Oncology (ASCO)

    Dr. John Jacobs

  11. Local therapy of cancer with free IL-2

    Article • Medical Oncology, February 2008, Springer Science + Business Media

    Dr. John Jacobs

  12. In vitro and in vivo protein delivery from in situ forming poly(ethylene glycol)–poly(lactide) hydrogels

    Article • Journal of Controlled Release, June 2007, Elsevier

    Dr. John Jacobs

  13. Treatment of ocular squamous cell carcinomas in cattle with interleukin‐2

    Article • Veterinary Record, November 2006, Wiley

    Dr. John Jacobs

  14. Genetic polymorphism of metabolic enzymes modifies the risk of chronic solvent-induced encephalopathy

    Article • Toxicology and Industrial Health, August 2006, SAGE Publications

    Dr. John Jacobs

  15. Stratum corneum cytokines and skin irritation response to sodium lauryl sulfate

    Article • Contact Dermatitis, June 2006, Wiley

    Dr. John Jacobs

  16. Skin irritants and contact sensitizers induce Langerhans cell migration and maturation at irritant concentration

    Article • Experimental Dermatology, May 2006, Wiley

    Dr. John Jacobs

  17. Subtoxic concentrations of allergenic haptens induce LC migration and maturation in a human organotypic skin explant culture model: a novel method for identifying potential contact allergens

    Article • Experimental Dermatology, May 2006, Wiley

    Dr. John Jacobs

  18. Local interleukin-2 and interleukin-12 therapy of bovine ocular squamous cell carcinomas

    Article • Veterinary Immunology and Immunopathology, July 2005, Elsevier

    Dr. John Jacobs

  19. Local interleukin 2 therapy is most effective against cancer when injected intratumourally

    Article • Medical Oncology, February 2005, Springer Science + Business Media

    Dr. John Jacobs

  20. Locoregional IL-2 low dose applications for gastrointestinal tumors

    Article • World Journal of Gastroenterology, January 2005, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr. John Jacobs

  21. Treatment of stage III–IV nasopharyngeal carcinomas by external beam irradiation and local low doses of IL-2

    Article • Medical Oncology, December 2004, Springer Science + Business Media

    Dr. John Jacobs

  22. Assessment of contact allergens by dissociation of irritant and sensitizing properties

    Article • Toxicology in Vitro, October 2004, Elsevier

    Dr. John Jacobs

  23. In situ crosslinked biodegradable hydrogels loaded with IL-2 are effective tools for local IL-2 therapy

    Article • European Journal of Pharmaceutical Sciences, March 2004, Elsevier

    Dr. John Jacobs

  24. A Two-centre Evaluation of the Human Organotypic Skin Explant Culture Model for Screening Contact Allergens

    Article • Alternatives to Laboratory Animals, November 2003, SAGE Publications

    Dr. John Jacobs

  25. Comparison of the efficacy of local treatment of equine sarcoids with IL-2 or cisplatin/IL-2

    Article • Medical Oncology, February 2003, Springer Science + Business Media

    Dr. John Jacobs

  26. An in vitro model for detecting skin irritants: methyl green-pyronine staining of human skin explant cultures

    Article • Toxicology in Vitro, October 2002, Elsevier

    Dr. John Jacobs

  27. An automated method for the quantification of immunostained human Langerhans cells

    Article • Journal of Immunological Methods, January 2001, Elsevier

    Dr. John Jacobs

  28. Methyl Green-Pyronine Staining of Porcine Organotypic Skin Explant Cultures: An Alternative Model for Screening for Skin Irritants

    Article • Alternatives to Laboratory Animals, March 2000, SAGE Publications

    Dr. John Jacobs

  29. Detection of varicella-zoster virus and herpes simplex virus by the polymerase chain reaction with degenerate primers

    Article • Journal of Virological Methods, December 1999, Elsevier

    Dr. John Jacobs