All Stories

  1. A Loss-of-Function Mutation in bco1l Underlies Yellow Coloration in Large Yellow Croaker (Larimichthys crocea)

    Article • Animals, March 2026, MDPI AG

    Professor Johannes von Lintig

  2. Retinoic acid production via the ray-finned fish gene bco1l is essential for juvenile development

    Article • Genetics, February 2026, Oxford University Press (OUP)

    Professor Johannes von Lintig

  3. Aster-B Modulates Oxidative Stress Responses and Carotenoid Distribution in ARPE-19 Cells

    Article • Antioxidants, May 2025, MDPI AG

    Professor Johannes von Lintig

  4. Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine

    Article • Journal of Lipid Research, March 2025, Elsevier

    Professor Johannes von Lintig

  5. The Absorption, Storage, and Transport of Ocular Carotenoids and Retinoids

    Article • Annual Review of Vision Science, September 2024, Annual Reviews

    Professor Johannes von Lintig

  6. Maternal genetics and diet modulate vitamin A homeostasis of the offspring and affect the susceptibility to obesity in adulthood in mice

    Article • AJP Endocrinology and Metabolism, September 2024, American Physiological Society

    Professor Johannes von Lintig

  7. Unraveling the mystery of ocular retinoid turnover: Insights from albino mice and the role of STRA6

    Article • Journal of Biological Chemistry, March 2024, Elsevier

    Professor Johannes von Lintig

  8. Bioavailability and provitamin A activity of neurosporaxanthin in mice

    Article • Communications Biology, October 2023, Springer Science + Business Media

    Professor Johannes von Lintig

  9. Genetic deletion of Bco2 and Isx establishes a golden mouse model for carotenoid research

    Article • Molecular Metabolism, July 2023, Elsevier

    Professor Johannes von Lintig

  10. Vitamin A deficiency compromises the barrier function of the retinal pigment epithelium

    Article • PNAS Nexus, May 2023, Oxford University Press (OUP)

    Professor Johannes von Lintig

  11. ASTER-B regulates mitochondrial carotenoid transport and homeostasis

    Article • Journal of Lipid Research, May 2023, Elsevier

    Professor Johannes von Lintig

  12. β-Cryptoxanthin Attenuates Cigarette-Smoke-Induced Lung Lesions in the Absence of Carotenoid Cleavage Enzymes (BCO1/BCO2) in Mice

    Article • Molecules, February 2023, MDPI AG

    Professor Johannes von Lintig

  13. Genetic tuning of β-carotene oxygenase-1 activity rescues cone photoreceptor function in STRA6-deficient mice

    Article • Human Molecular Genetics, September 2022, Oxford University Press (OUP)

    Professor Johannes von Lintig

  14. Aster la vista: Unraveling the biochemical basis of carotenoid homeostasis in the human retina

    Article • BioEssays, September 2022, Wiley

    Professor Johannes von Lintig

  15. Diabetes Aggravates Photoreceptor Pathologies in a Mouse Model for Ocular Vitamin A Deficiency

    Article • Antioxidants, June 2022, MDPI AG

    Professor Johannes von Lintig

  16. Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A

    Article • Journal of Lipid Research, June 2022, Elsevier

    Professor Johannes von Lintig

  17. Aster proteins mediate carotenoid transport in mammalian cells

    Article • Proceedings of the National Academy of Sciences, April 2022, Proceedings of the National Academy of Sciences

    Professor Johannes von Lintig

  18. Genomic consequences of domestication of the Siamese fighting fish

    Article • Science Advances, March 2022, American Association for the Advancement of Science

    Professor Johannes von Lintig

  19. Carotenoid modifying enzymes in metazoans

    Article • January 2022, Elsevier

    Professor Johannes von Lintig

  20. Expression and biochemical analyses of proteins involved in the transport of carotenoids and retinoids

    Article • January 2022, Elsevier

    Professor Johannes von Lintig

  21. Author response: Disturbed retinoid metabolism upon loss of rlbp1a impairs cone function and leads to subretinal lipid deposits and photoreceptor degeneration in the zebrafish retina

    Article • October 2021, eLife

    Professor Johannes von Lintig

  22. The vitamin A transporter STRA6 adjusts the stoichiometry of chromophore and opsins in visual pigment synthesis and recycling

    Article • Human Molecular Genetics, September 2021, Oxford University Press (OUP)

    Professor Johannes von Lintig

  23. Disturbed retinoid metabolism upon loss of rlbp1a impairs cone function and leads to subretinal lipid deposits and photoreceptor degeneration in the zebrafish retina

    Article • June 2021, Cold Spring Harbor Laboratory Press

    Professor Johannes von Lintig

  24. The Structural and Biochemical Basis of Apocarotenoid Processing by β-Carotene Oxygenase-2

    Article • ACS Chemical Biology, February 2021, American Chemical Society (ACS)

    Professor Johannes von Lintig

  25. Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1

    Article • Journal of Clinical Investigation, February 2021, American Society for Clinical Investigation

    Professor Johannes von Lintig

  26. Molecular components affecting ocular carotenoid and retinoid homeostasis

    Article • Progress in Retinal and Eye Research, January 2021, Elsevier

    Professor Johannes von Lintig

  27. LRAT coordinates the negative-feedback regulation of intestinal retinoid biosynthesis from β-carotene

    Article • Journal of Lipid Research, January 2021, Elsevier

    Professor Johannes von Lintig

  28. β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice

    Article • Journal of Lipid Research, November 2020, Elsevier

    Professor Johannes von Lintig

  29. The human mitochondrial enzyme BCO2 exhibits catalytic activity toward carotenoids and apocarotenoids

    Article • Journal of Biological Chemistry, November 2020, Elsevier

    Professor Johannes von Lintig

  30. Biology of carotenoids in mammals

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, November 2020, Elsevier

    Professor Johannes von Lintig

  31. Carotenoid metabolism at the intestinal barrier

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, November 2020, Elsevier

    Professor Johannes von Lintig

  32. Overlapping Vitamin A Interventions with Provitamin A Carotenoids and Preformed Vitamin A Cause Excessive Liver Retinol Stores in Male Mongolian Gerbils

    Article • Journal of Nutrition, November 2020, Elsevier

    Professor Johannes von Lintig

  33. Astaxanthin-Shifted Gut Microbiota Is Associated with Inflammation and Metabolic Homeostasis in Mice

    Article • Journal of Nutrition, October 2020, Elsevier

    Professor Johannes von Lintig

  34. Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase

    Article • Proceedings of the National Academy of Sciences, August 2020, Proceedings of the National Academy of Sciences

    Philip Kiser, Professor Johannes von Lintig

  35. Eat Your Carrots! β-Carotene and Cholesterol Homeostasis

    Article • Journal of Nutrition, August 2020, Elsevier

    Professor Johannes von Lintig

  36. Vitamin A and Other Carotenoids

    Article • January 2020, Elsevier

    Professor Johannes von Lintig

  37. Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color

    Article • Scientific Reports, December 2019, Springer Science + Business Media

    Professor Johannes von Lintig

  38. Expression and Characterization of Mammalian Carotenoid Cleavage Dioxygenases

    Article • November 2019, Springer Science + Business Media

    Professor Johannes von Lintig

  39. Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases

    Article • Journal of Biological Chemistry, July 2019, Elsevier

    Professor Johannes von Lintig

  40. Characterization of the novel role of NinaB orthologs from Bombyx mori and Tribolium castaneum

    Article • Insect Biochemistry and Molecular Biology, June 2019, Elsevier

    Professor Johannes von Lintig

  41. News and views about carotenoids: Red-hot and true

    Article • Archives of Biochemistry and Biophysics, November 2018, Elsevier

    Professor Johannes von Lintig

  42. Dietary vitamin A impacts DNA methylation patterns of adipogenesis-related genes in suckling rats

    Article • Archives of Biochemistry and Biophysics, July 2018, Elsevier

    Professor Johannes von Lintig

  43. Preparation and characterization of metal-substituted carotenoid cleavage oxygenases

    Article • JBIC Journal of Biological Inorganic Chemistry, June 2018, Springer Science + Business Media

    Professor Johannes von Lintig

  44. Protective role of carotenoids in the visual cycle

    Article • The FASEB Journal, June 2018, Wiley

    Made Airanthi Kusuma Widjaja-Adhi, Professor Johannes von Lintig

  45. The Biochemical Basis of Vitamin A Production from the Asymmetric Carotenoid β-Cryptoxanthin

    Article • ACS Chemical Biology, June 2018, American Chemical Society (ACS)

    Professor Johannes von Lintig

  46. Abstract 210: Beta-carotene Conversion to Vitamin a Delays Atherosclerosis Progression and Accelerates Atherosclerosis Regression

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2018, Wolters Kluwer Health

    Professor Johannes von Lintig

  47. Correction

    Article • Molecular Nutrition & Food Research, April 2018, Wiley

    Professor Johannes von Lintig

  48. Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice

    Article • Molecular Nutrition & Food Research, March 2018, Wiley

    Professor Johannes von Lintig

  49. Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration

    Article • Molecular and Cellular Biology, October 2017, ASM Journals

    Professor Johannes von Lintig

  50. Transcription factor ISX mediates the cross talk between diet and immunity

    Article • Proceedings of the National Academy of Sciences, October 2017, Proceedings of the National Academy of Sciences

    Made Airanthi Kusuma Widjaja-Adhi, Professor Johannes von Lintig

  51. Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center

    Article • Biochemistry, May 2017, American Chemical Society (ACS)

    Professor Johannes von Lintig

  52. Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies

    Article • The American Journal of Human Genetics, April 2017, Elsevier

    Professor Johannes von Lintig

  53. Lack of β, β‐carotene‐9′, 10′‐oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice

    Article • Molecular Nutrition & Food Research, February 2017, Wiley

    Professor Johannes von Lintig

  54. Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family

    Article • Biochemistry, November 2016, American Chemical Society (ACS)

    Professor Johannes von Lintig

  55. Transport of vitamin A across blood–tissue barriers is facilitated by STRA6

    Article • The FASEB Journal, August 2016, Federation of American Societies For Experimental Biology (FASEB)

    Professor Johannes von Lintig, Made Airanthi Kusuma Widjaja-Adhi

  56. Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism

    Article • Journal of Lipid Research, July 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Made Airanthi Kusuma Widjaja-Adhi, Professor Johannes von Lintig

  57. The Biochemical Basis of Vitamin A3 Production in Arthropod Vision

    Article • ACS Chemical Biology, February 2016, American Chemical Society (ACS)

    Professor Johannes von Lintig

  58. Utilization of Dioxygen by Carotenoid Cleavage Oxygenases

    Article • Journal of Biological Chemistry, December 2015, Elsevier

    Professor Johannes von Lintig

  59. Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7

    Article • PLOS One, November 2015, PLOS

    Professor Johannes von Lintig

  60. Characterization of the Role of β-Carotene 9,10-Dioxygenase in Macular Pigment Metabolism

    Article • Journal of Biological Chemistry, August 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Made Airanthi Kusuma Widjaja-Adhi, Professor Johannes von Lintig

  61. Retinylamine Benefits Early Diabetic Retinopathy in Mice

    Article • Journal of Biological Chemistry, August 2015, Elsevier

    Professor Johannes von Lintig

  62. A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption

    Article • Human Molecular Genetics, February 2015, Oxford University Press (OUP)

    Made Airanthi Kusuma Widjaja-Adhi, Professor Johannes von Lintig

  63. Lycopene and Apo-10′-lycopenoic Acid Have Differential Mechanisms of Protection against Hepatic Steatosis in β-Carotene-9′,10′-oxygenase Knockout Male Mice1–3

    Article • Journal of Nutrition, December 2014, Oxford University Press (OUP)

    Professor Xiang-Dong Wang, Professor Johannes von Lintig

  64. Vitamin A metabolism in day light vision

    Article • The FASEB Journal, October 2014, Federation of American Societies For Experimental Biology (FASEB)

    Professor Johannes von Lintig

  65. Lycopene Attenuated Hepatic Tumorigenesis via Differential Mechanisms Depending on Carotenoid Cleavage Enzyme in Mice

    Article • Cancer Prevention Research, October 2014, American Association for Cancer Research (AACR)

    Professor Xiang-Dong Wang, Professor Johannes von Lintig

  66. β‐Carotene during the suckling period is absorbed intact and induces retinoic acid dependent responses similar to preformed vitamin A in intestine and liver, but not adipose tissue of young rats

    Article • Molecular Nutrition & Food Research, September 2014, Wiley

    Professor Johannes von Lintig

  67. A Mouse Model for Studying Cone Photoreceptor Pathologies

    Article • Investigative Ophthalmology & Visual Science, August 2014, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Johannes von Lintig

  68. Evidence for compartmentalization of mammalian carotenoid metabolism

    Article • The FASEB Journal, July 2014, Wiley

    Professor Johannes von Lintig

  69. STRA6 is critical for cellular vitamin A uptake and homeostasis

    Article • Human Molecular Genetics, May 2014, Oxford University Press (OUP)

    Professor Johannes von Lintig

  70. Diabetes-Induced Impairment in Visual Function in Mice: Contributions of p38 MAPK, RAGE, Leukocytes, and Aldose Reductase

    Article • Investigative Ophthalmology & Visual Science, May 2014, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Johannes von Lintig

  71. Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO)

    Article • Journal of Biological Chemistry, May 2014, Elsevier

    Professor Johannes von Lintig

  72. Carotenoids

    Article • Archives of Biochemistry and Biophysics, November 2013, Elsevier

    Dr Helmut Sies, Professor Johannes von Lintig

  73. Characterization of human β,β-carotene-15,15′-monooxygenase (BCMO1) as a soluble monomeric enzyme

    Article • Archives of Biochemistry and Biophysics, November 2013, Elsevier

    Professor Johannes von Lintig

  74. Structural basis of carotenoid cleavage: From bacteria to mammals

    Article • Archives of Biochemistry and Biophysics, November 2013, Elsevier

    Professor Johannes von Lintig

  75. Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism

    Article • Journal of Biological Chemistry, October 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Made Airanthi Kusuma Widjaja-Adhi, Professor Johannes von Lintig

  76. Genetic Ablation of the Fatty Acid–Binding Protein FABP5 Suppresses HER2-Induced Mammary Tumorigenesis

    Article • Cancer Research, July 2013, American Association for Cancer Research (AACR)

    Professor Johannes von Lintig

  77. Genetics and Diet Regulate Vitamin A Production via the Homeobox Transcription Factor ISX

    Article • Journal of Biological Chemistry, March 2013, Elsevier

    Professor Johannes von Lintig

  78. Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain

    Article • Journal of Neuroscience, February 2013, Society for Neuroscience

    Professor Johannes von Lintig

  79. Vitamin A supplementation in early life affects later response to an obesogenic diet in rats

    Article • International Journal of Obesity, December 2012, Springer Science + Business Media

    Professor Johannes von Lintig

  80. Provitamin A metabolism and functions in mammalian biology

    Article • American Journal of Clinical Nutrition, November 2012, Elsevier

    Professor Johannes von Lintig

  81. In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death

    Article • Human Molecular Genetics, October 2012, Oxford University Press (OUP)

    Professor Johannes von Lintig

  82. BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway

    Article • Development, August 2012, The Company of Biologists

    Professor Johannes von Lintig

  83. Lecithin:Retinol Acyltransferase Is Critical for Cellular Uptake of Vitamin A from Serum Retinol-binding Protein

    Article • Journal of Biological Chemistry, July 2012, Elsevier

    Professor Johannes von Lintig

  84. TheDrosophilaVisual Cycle andDe NovoChromophore Synthesis Depends onrdhB

    Article • Journal of Neuroscience, March 2012, Society for Neuroscience

    Professor Johannes von Lintig

  85. Differential Expression of the Demosponge (Suberites domuncula) Carotenoid Oxygenases in Response to Light: Protection Mechanism Against the Self-Produced Toxic Protein (Suberitine)

    Article • Marine Drugs, January 2012, MDPI AG

    Professor Johannes von Lintig

  86. Mammalian Carotenoid-oxygenases: Key players for carotenoid function and homeostasis

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, January 2012, Elsevier

    Professor Johannes von Lintig

  87. Metabolism of Carotenoids and Retinoids Related to Vision

    Article • Journal of Biological Chemistry, January 2012, Elsevier

    Professor Johannes von Lintig

  88. Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, December 2011, Elsevier

    Professor Johannes von Lintig

  89. Dietary 9-cis-β,β-Carotene Fails to Rescue Vision in Mouse Models of Leber Congenital Amaurosis

    Article • Molecular Pharmacology, August 2011, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Johannes von Lintig

  90. Gene expression response of mouse lung, liver and white adipose tissue to β-carotene supplementation, knockout of Bcmo1 and sex

    Article • Molecular Nutrition & Food Research, July 2011, Wiley

    dr Jean-Francois Landrier, Professor Johannes von Lintig

  91. Beta-Carotene Reduces Body Adiposity of Mice via BCMO1

    Article • PLOS One, June 2011, PLOS

    dr Jean-Francois Landrier, Professor Johannes von Lintig

  92. Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid

    Article • Archives of Biochemistry and Biophysics, December 2010, Elsevier

    Ken Riedl, Professor Johannes von Lintig

  93. Loss of Carotene-9′,10'-Monooxygenase Expression Increases Serum and Tissue Lycopene Concentrations in Lycopene-Fed Mice

    Article • Journal of Nutrition, December 2010, Elsevier

    Professor Johannes von Lintig

  94. In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death

    Article • Human Molecular Genetics, November 2010, Oxford University Press (OUP)

    Professor Johannes von Lintig

  95. A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

    Article • The FASEB Journal, November 2010, Wiley

    Professor Johannes von Lintig

  96. β,β-Carotene Decreases Peroxisome Proliferator Receptor γ Activity and Reduces Lipid Storage Capacity of Adipocytes in a β,β-Carotene Oxygenase 1-dependent Manner

    Article • Journal of Biological Chemistry, September 2010, Elsevier

    Professor Johannes von Lintig

  97. Colors with Functions: Elucidating the Biochemical and Molecular Basis of Carotenoid Metabolism

    Article • Annual Review of Nutrition, July 2010, Annual Reviews

    Professor Johannes von Lintig

  98. The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision

    Article • Trends in Biochemical Sciences, July 2010, Elsevier

    Professor Johannes von Lintig

  99. Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1−/− mice

    Article • Carcinogenesis, May 2010, Oxford University Press (OUP)

    Professor Johannes von Lintig

  100. Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene

    Article • Cellular and Molecular Life Sciences, April 2010, Springer Science + Business Media

    Professor Johannes von Lintig

  101. ISX is a retinoic acid‐sensitive gatekeeper that controls intestinal β,β‐carotene absorption and vitamin A production

    Article • The FASEB Journal, January 2010, Wiley

    Professor Johannes von Lintig

  102. NinaB Is Essential for Drosophila Vision but Induces Retinal Degeneration in Opsin-deficient Photoreceptors

    Article • Journal of Biological Chemistry, January 2010, Elsevier

    Professor Johannes von Lintig

  103. Requirement for an Enzymatic Visual Cycle in Drosophila

    Article • Current Biology, January 2010, Elsevier

    Professor Johannes von Lintig

  104. Increased adiposity in the retinol saturase‐knockout mouse

    Article • The FASEB Journal, November 2009, Wiley

    Professor Johannes von Lintig

  105. Activation of Retinoic Acid Receptors by Dihydroretinoids

    Article • Molecular Pharmacology, September 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Johannes von Lintig

  106. β-Carotene conversion products and their effects on adipose tissue

    Article • Genes & Nutrition, June 2009, Springer Science + Business Media

    dr Jean-Francois Landrier, Professor Johannes von Lintig

  107. In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death

    Article • Human Molecular Genetics, January 2009, Oxford University Press (OUP)

    Professor Johannes von Lintig

  108. Two common single nucleotide polymorphisms in the gene encoding β‐carotene 15,15′‐monoxygenase alter β‐carotene metabolism in female volunteers

    Article • The FASEB Journal, December 2008, Wiley

    Professor Johannes von Lintig

  109. NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide

    Article • Proceedings of the National Academy of Sciences, December 2008, Proceedings of the National Academy of Sciences

    Professor Johannes von Lintig

  110. Subfunctionalization of a Retinoid-Binding Protein Provides Evidence for Two Parallel Visual Cycles in the Cone-Dominant Zebrafish Retina

    Article • Journal of Neuroscience, August 2008, Society for Neuroscience

    Professor Johannes von Lintig

  111. Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina

    Article • Journal of Biological Chemistry, April 2008, Elsevier

    Professor Johannes von Lintig

  112. RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome

    Article • Cell Metabolism, March 2008, Elsevier

    Yoshikazu Imanishi, Professor Johannes von Lintig

  113. CMO1 Deficiency Abolishes Vitamin A Production from β-Carotene and Alters Lipid Metabolism in Mice

    Article • Journal of Biological Chemistry, November 2007, Elsevier

    Professor Johannes von Lintig

  114. R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal

    Article • Human Molecular Genetics, October 2007, Oxford University Press (OUP)

    Professor Johannes von Lintig

  115. Evidence for RPE65‐independent vision in the cone‐dominated zebrafish retina

    Article • European Journal of Neuroscience, September 2007, Wiley

    Professor Stephan CF Neuhauss, Professor Johannes von Lintig

  116. RPE65 Is Essential for the Function of Cone Photoreceptors in NRL-Deficient Mice

    Article • Investigative Ophthalmology & Visual Science, February 2007, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Johannes von Lintig

  117. Specificity of Zebrafish Retinol Saturase:  Formation of All-trans-13,14-dihydroretinol and All-trans-7,8- dihydroretinol

    Article • Biochemistry, January 2007, American Chemical Society (ACS)

    Professor Johannes von Lintig

  118. Conversion of β‐Carotene to Retinal Pigment

    Article • January 2007, Elsevier

    Professor Johannes von Lintig

  119. Sequestration of Retinyl Esters Is Essential for Retinoid Signaling in the Zebrafish Embryo

    Article • Journal of Biological Chemistry, January 2007, Elsevier

    Professor Johannes von Lintig

  120. The Drosophila Class B Scavenger Receptor NinaD-I Is a Cell Surface Receptor Mediating Carotenoid Transport for Visual Chromophore Synthesis

    Article • Biochemistry, October 2006, American Chemical Society (ACS)

    Professor Johannes von Lintig

  121. β-Carotene Conversion into Vitamin A in Human Retinal Pigment Epithelial Cells

    Article • Investigative Ophthalmology & Visual Science, October 2005, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Johannes von Lintig

  122. A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision

    Article • Developmental Biology, August 2005, Elsevier

    Professor Stephan CF Neuhauss, Professor Johannes von Lintig

  123. The Retinal G Protein-coupled Receptor (RGR) Enhances Isomerohydrolase Activity Independent of Light

    Article • Journal of Biological Chemistry, August 2005, Elsevier

    Professor Johannes von Lintig

  124. Towards a better understanding of carotenoid metabolism in animals

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, May 2005, Elsevier

    Professor Johannes von Lintig

  125. Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids

    Article • Trends in Plant Science, April 2005, Elsevier

    Professor Johannes von Lintig

  126. Photoreceptor morphology is severely affected in the β,β‐carotene‐15,15′‐oxygenase (bcox) zebrafish morphant

    Article • European Journal of Neuroscience, January 2005, Wiley

    Professor Johannes von Lintig

  127. Vitamin A Formation in Animals: Molecular Identification and Functional Characterization of Carotene Cleaving Enzymes

    Article • Journal of Nutrition, January 2004, Elsevier

    Professor Johannes von Lintig

  128. Provitamin A conversion to retinal via theβ,β-carotene-15,15′-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis

    Article • Development, May 2003, The Company of Biologists

    Professor Johannes von Lintig

  129. Carotenoid oxygenases: cleave it or leave it

    Article • Trends in Plant Science, April 2003, Elsevier

    Professor Johannes von Lintig

  130. Structural and functional characterization of the phytoene synthase promoter from Arabidopsis thaliana

    Article • Planta, January 2003, Springer Science + Business Media

    Professor Johannes von Lintig

  131. A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila

    Article • Proceedings of the National Academy of Sciences, July 2002, Proceedings of the National Academy of Sciences

    Professor Johannes von Lintig

  132. Identification and Characterization of a Mammalian Enzyme Catalyzing the Asymmetric Oxidative Cleavage of Provitamin A

    Article • Journal of Biological Chemistry, April 2001, Elsevier

    Professor Johannes von Lintig

  133. Analysis of the blind Drosophila mutant ninaB identifies the gene encoding the key enzyme for vitamin A formation invivo

    Article • Proceedings of the National Academy of Sciences, January 2001, Proceedings of the National Academy of Sciences

    Professor Johannes von Lintig

  134. Molecular Analysis of Vitamin A Formation: Cloning and Characterization of β-Carotene 15,15′-Dioxygenases

    Article • Archives of Biochemistry and Biophysics, January 2001, Elsevier

    Professor Johannes von Lintig

  135. Regulation and activation of phytoene synthase, a key enzyme in carotenoid biosynthesis, during photomorphogenesis

    Article • Planta, November 2000, Springer Science + Business Media

    Professor Johannes von Lintig

  136. Filling the Gap in Vitamin A Research

    Article • Journal of Biological Chemistry, April 2000, Elsevier

    Professor Johannes von Lintig

  137. Induced β-Carotene Synthesis Driven by Triacylglycerol Deposition in the Unicellular AlgaDunaliella bardawil1

    Article • PLANT PHYSIOLOGY, April 1998, Oxford University Press (OUP)

    Professor Johannes von Lintig

  138. Light‐dependent regulation of carotenoid biosynthesis occurs at the level of phytoene synthase expression and is mediated by phytochrome in Sinapis alba and Arabidopsis thaliana seedlings

    Article • The Plant Journal, September 1997, Wiley

    Professor Johannes von Lintig

  139. Chloroplast Import of Four Carotenoid Biosynthetic Enzymes In Vitro Reveals Differential Fates Prior to Membrane Binding and Oligomeric Assembly

    Article • FEBS Journal, August 1997, Wiley

    Professor Johannes von Lintig

  140. Transgenic rice (Oryza sativa) endosperm expressing daffodil (Narcissus pseudonarcissus) phytoene synthase accumulates phytoene, a key intermediate of provitamin A biosynthesis

    Article • The Plant Journal, May 1997, Wiley

    Professor Johannes von Lintig

  141. Phytoene synthase from Narcissus pseudonarcissus: functional expression, galactolipid requirement, topological distribution in chromoplasts and induction during flowering

    Article • The Plant Journal, November 1996, Wiley

    Professor Johannes von Lintig

  142. A novel, soluble form of phytoene desaturase from Narcissus pseudonarcissus chromoplasts is Hsp70‐complexed and competent for flavinylation, membrane association and enzymatic activation

    Article • The Plant Journal, May 1996, Wiley

    Professor Johannes von Lintig

  143. Ti plasmid-encoded octopine and nopaline catabolism in Agrobacterium: specificities of the LysR-type regulators OccR and NocR, and protein-induced DNA bending

    Article • MGG Molecular & General Genetics, January 1995, Springer Science + Business Media

    Professor Johannes von Lintig

  144. Opine-regulated promoters and LysR-type regulators in the nopaline (noc) and octopine (occ) catabolic regions of Ti plasmids of Agrobacterium tumefaciens

    Article • Journal of Bacteriology, January 1994, ASM Journals

    Professor Johannes von Lintig

  145. Opine transport genes in the octopine (occ) and nopaline (noc) catabolic regions in Ti plasmids of Agrobacterium tumefaciens

    Article • Journal of Bacteriology, February 1992, ASM Journals

    Professor Johannes von Lintig

  146. Positive Regulators of Opine-Inducible Promoters in the Nopaline and Octopine Catabolism Regions of Ti Plasmids

    Article • Molecular Plant-Microbe Interactions, January 1991, Scientific Societies

    Professor Johannes von Lintig

  147. Temperature-sensitive step in Ti plasmid vir-region induction and correlation with cytokinin secretion by Agrobacteria

    Article • MGG Molecular & General Genetics, July 1988, Springer Science + Business Media

    Professor Johannes von Lintig