All Stories

  1. Aster-B Modulates Oxidative Stress Responses and Carotenoid Distribution in ARPE-19 Cells
  2. Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine
  3. The Absorption, Storage, and Transport of Ocular Carotenoids and Retinoids
  4. Maternal genetics and diet modulate vitamin A homeostasis of the offspring and affect the susceptibility to obesity in adulthood in mice
  5. Unraveling the mystery of ocular retinoid turnover: Insights from albino mice and the role of STRA6
  6. Bioavailability and provitamin A activity of neurosporaxanthin in mice
  7. Genetic deletion of Bco2 and Isx establishes a golden mouse model for carotenoid research
  8. Vitamin A deficiency compromises the barrier function of the retinal pigment epithelium
  9. ASTER-B regulates mitochondrial carotenoid transport and homeostasis
  10. β-Cryptoxanthin Attenuates Cigarette-Smoke-Induced Lung Lesions in the Absence of Carotenoid Cleavage Enzymes (BCO1/BCO2) in Mice
  11. Genetic tuning of β-carotene oxygenase-1 activity rescues cone photoreceptor function in STRA6-deficient mice
  12. Aster la vista: Unraveling the biochemical basis of carotenoid homeostasis in the human retina
  13. Diabetes Aggravates Photoreceptor Pathologies in a Mouse Model for Ocular Vitamin A Deficiency
  14. Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A
  15. Aster proteins mediate carotenoid transport in mammalian cells
  16. Genomic consequences of domestication of the Siamese fighting fish
  17. Carotenoid modifying enzymes in metazoans
  18. Expression and biochemical analyses of proteins involved in the transport of carotenoids and retinoids
  19. Author response: Disturbed retinoid metabolism upon loss of rlbp1a impairs cone function and leads to subretinal lipid deposits and photoreceptor degeneration in the zebrafish retina
  20. The vitamin A transporter STRA6 adjusts the stoichiometry of chromophore and opsins in visual pigment synthesis and recycling
  21. Disturbed retinoid metabolism upon loss of rlbp1a impairs cone function and leads to subretinal lipid deposits and photoreceptor degeneration in the zebrafish retina
  22. The Structural and Biochemical Basis of Apocarotenoid Processing by β-Carotene Oxygenase-2
  23. Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1
  24. Molecular components affecting ocular carotenoid and retinoid homeostasis
  25. LRAT coordinates the negative-feedback regulation of intestinal retinoid biosynthesis from β-carotene
  26. β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice
  27. The human mitochondrial enzyme BCO2 exhibits catalytic activity toward carotenoids and apocarotenoids
  28. Biology of carotenoids in mammals
  29. Carotenoid metabolism at the intestinal barrier
  30. Overlapping Vitamin A Interventions with Provitamin A Carotenoids and Preformed Vitamin A Cause Excessive Liver Retinol Stores in Male Mongolian Gerbils
  31. Astaxanthin-Shifted Gut Microbiota Is Associated with Inflammation and Metabolic Homeostasis in Mice
  32. Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase
  33. Eat Your Carrots! β-Carotene and Cholesterol Homeostasis
  34. Vitamin A and Other Carotenoids
  35. Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color
  36. Expression and Characterization of Mammalian Carotenoid Cleavage Dioxygenases
  37. Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases
  38. Characterization of the novel role of NinaB orthologs from Bombyx mori and Tribolium castaneum
  39. News and views about carotenoids: Red-hot and true
  40. Dietary vitamin A impacts DNA methylation patterns of adipogenesis-related genes in suckling rats
  41. Preparation and characterization of metal-substituted carotenoid cleavage oxygenases
  42. Protective role of carotenoids in the visual cycle
  43. The Biochemical Basis of Vitamin A Production from the Asymmetric Carotenoid β-Cryptoxanthin
  44. Abstract 210: Beta-carotene Conversion to Vitamin a Delays Atherosclerosis Progression and Accelerates Atherosclerosis Regression
  45. Correction
  46. Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice
  47. Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration
  48. Transcription factor ISX mediates the cross talk between diet and immunity
  49. Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center
  50. Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies
  51. Lack of β, β‐carotene‐9′, 10′‐oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice
  52. Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family
  53. Transport of vitamin A across blood–tissue barriers is facilitated by STRA6
  54. Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism
  55. The Biochemical Basis of Vitamin A3 Production in Arthropod Vision
  56. Utilization of Dioxygen by Carotenoid Cleavage Oxygenases
  57. Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7
  58. Characterization of the Role of β-Carotene 9,10-Dioxygenase in Macular Pigment Metabolism
  59. Retinylamine Benefits Early Diabetic Retinopathy in Mice
  60. A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption
  61. Lycopene and Apo-10′-lycopenoic Acid Have Differential Mechanisms of Protection against Hepatic Steatosis in β-Carotene-9′,10′-oxygenase Knockout Male Mice1–3
  62. Vitamin A metabolism in day light vision
  63. Lycopene Attenuated Hepatic Tumorigenesis via Differential Mechanisms Depending on Carotenoid Cleavage Enzyme in Mice
  64. β‐Carotene during the suckling period is absorbed intact and induces retinoic acid dependent responses similar to preformed vitamin A in intestine and liver, but not adipose tissue of young rats
  65. A Mouse Model for Studying Cone Photoreceptor Pathologies
  66. Evidence for compartmentalization of mammalian carotenoid metabolism
  67. STRA6 is critical for cellular vitamin A uptake and homeostasis
  68. Diabetes-Induced Impairment in Visual Function in Mice: Contributions of p38 MAPK, RAGE, Leukocytes, and Aldose Reductase
  69. Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO)
  70. Carotenoids
  71. Characterization of human β,β-carotene-15,15′-monooxygenase (BCMO1) as a soluble monomeric enzyme
  72. Structural basis of carotenoid cleavage: From bacteria to mammals
  73. Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism
  74. Genetic Ablation of the Fatty Acid–Binding Protein FABP5 Suppresses HER2-Induced Mammary Tumorigenesis
  75. Genetics and Diet Regulate Vitamin A Production via the Homeobox Transcription Factor ISX
  76. Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain
  77. Vitamin A supplementation in early life affects later response to an obesogenic diet in rats
  78. Provitamin A metabolism and functions in mammalian biology
  79. In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death
  80. BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway
  81. Lecithin:Retinol Acyltransferase Is Critical for Cellular Uptake of Vitamin A from Serum Retinol-binding Protein
  82. TheDrosophilaVisual Cycle andDe NovoChromophore Synthesis Depends onrdhB
  83. Differential Expression of the Demosponge (Suberites domuncula) Carotenoid Oxygenases in Response to Light: Protection Mechanism Against the Self-Produced Toxic Protein (Suberitine)
  84. Mammalian Carotenoid-oxygenases: Key players for carotenoid function and homeostasis
  85. Metabolism of Carotenoids and Retinoids Related to Vision
  86. Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1
  87. Dietary 9-cis-β,β-Carotene Fails to Rescue Vision in Mouse Models of Leber Congenital Amaurosis
  88. Gene expression response of mouse lung, liver and white adipose tissue to β-carotene supplementation, knockout of Bcmo1 and sex
  89. Beta-Carotene Reduces Body Adiposity of Mice via BCMO1
  90. Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid
  91. Loss of Carotene-9′,10'-Monooxygenase Expression Increases Serum and Tissue Lycopene Concentrations in Lycopene-Fed Mice
  92. In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death
  93. A mitochondrial enzyme degrades carotenoids and protects against oxidative stress
  94. β,β-Carotene Decreases Peroxisome Proliferator Receptor γ Activity and Reduces Lipid Storage Capacity of Adipocytes in a β,β-Carotene Oxygenase 1-dependent Manner
  95. Colors with Functions: Elucidating the Biochemical and Molecular Basis of Carotenoid Metabolism
  96. The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision
  97. Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1−/− mice
  98. Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene
  99. ISX is a retinoic acid‐sensitive gatekeeper that controls intestinal β,β‐carotene absorption and vitamin A production
  100. NinaB Is Essential for Drosophila Vision but Induces Retinal Degeneration in Opsin-deficient Photoreceptors
  101. Requirement for an Enzymatic Visual Cycle in Drosophila
  102. Increased adiposity in the retinol saturase‐knockout mouse
  103. Activation of Retinoic Acid Receptors by Dihydroretinoids
  104. β-Carotene conversion products and their effects on adipose tissue
  105. In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death
  106. Two common single nucleotide polymorphisms in the gene encoding β‐carotene 15,15′‐monoxygenase alter β‐carotene metabolism in female volunteers
  107. NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide
  108. Subfunctionalization of a Retinoid-Binding Protein Provides Evidence for Two Parallel Visual Cycles in the Cone-Dominant Zebrafish Retina
  109. Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina
  110. RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome
  111. CMO1 Deficiency Abolishes Vitamin A Production from β-Carotene and Alters Lipid Metabolism in Mice
  112. R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal
  113. Evidence for RPE65‐independent vision in the cone‐dominated zebrafish retina
  114. RPE65 Is Essential for the Function of Cone Photoreceptors in NRL-Deficient Mice
  115. Specificity of Zebrafish Retinol Saturase:  Formation of All-trans-13,14-dihydroretinol and All-trans-7,8- dihydroretinol
  116. Conversion of β‐Carotene to Retinal Pigment
  117. Sequestration of Retinyl Esters Is Essential for Retinoid Signaling in the Zebrafish Embryo
  118. The Drosophila Class B Scavenger Receptor NinaD-I Is a Cell Surface Receptor Mediating Carotenoid Transport for Visual Chromophore Synthesis
  119. β-Carotene Conversion into Vitamin A in Human Retinal Pigment Epithelial Cells
  120. A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision
  121. The Retinal G Protein-coupled Receptor (RGR) Enhances Isomerohydrolase Activity Independent of Light
  122. Towards a better understanding of carotenoid metabolism in animals
  123. Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids
  124. Photoreceptor morphology is severely affected in the β,β‐carotene‐15,15′‐oxygenase (bcox) zebrafish morphant
  125. Vitamin A Formation in Animals: Molecular Identification and Functional Characterization of Carotene Cleaving Enzymes
  126. Provitamin A conversion to retinal via theβ,β-carotene-15,15′-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis
  127. Carotenoid oxygenases: cleave it or leave it
  128. Structural and functional characterization of the phytoene synthase promoter from Arabidopsis thaliana
  129. A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila
  130. Identification and Characterization of a Mammalian Enzyme Catalyzing the Asymmetric Oxidative Cleavage of Provitamin A
  131. Analysis of the blind Drosophila mutant ninaB identifies the gene encoding the key enzyme for vitamin A formation invivo
  132. Molecular Analysis of Vitamin A Formation: Cloning and Characterization of β-Carotene 15,15′-Dioxygenases
  133. Regulation and activation of phytoene synthase, a key enzyme in carotenoid biosynthesis, during photomorphogenesis
  134. Filling the Gap in Vitamin A Research
  135. Induced β-Carotene Synthesis Driven by Triacylglycerol Deposition in the Unicellular AlgaDunaliella bardawil1
  136. Light‐dependent regulation of carotenoid biosynthesis occurs at the level of phytoene synthase expression and is mediated by phytochrome in Sinapis alba and Arabidopsis thaliana seedlings
  137. Chloroplast Import of Four Carotenoid Biosynthetic Enzymes In Vitro Reveals Differential Fates Prior to Membrane Binding and Oligomeric Assembly
  138. Transgenic rice (Oryza sativa) endosperm expressing daffodil (Narcissus pseudonarcissus) phytoene synthase accumulates phytoene, a key intermediate of provitamin A biosynthesis
  139. Phytoene synthase from Narcissus pseudonarcissus: functional expression, galactolipid requirement, topological distribution in chromoplasts and induction during flowering
  140. A novel, soluble form of phytoene desaturase from Narcissus pseudonarcissus chromoplasts is Hsp70‐complexed and competent for flavinylation, membrane association and enzymatic activation
  141. Ti plasmid-encoded octopine and nopaline catabolism in Agrobacterium: specificities of the LysR-type regulators OccR and NocR, and protein-induced DNA bending
  142. Opine-regulated promoters and LysR-type regulators in the nopaline (noc) and octopine (occ) catabolic regions of Ti plasmids of Agrobacterium tumefaciens
  143. Opine transport genes in the octopine (occ) and nopaline (noc) catabolic regions in Ti plasmids of Agrobacterium tumefaciens
  144. Positive Regulators of Opine-Inducible Promoters in the Nopaline and Octopine Catabolism Regions of Ti Plasmids
  145. Temperature-sensitive step in Ti plasmid vir-region induction and correlation with cytokinin secretion by Agrobacteria