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  1. Cryo-EM and X-ray structures of an anti-MHC-I monoclonal antibody/H2-K b complex reveal the basis of conformational dependence and allelic specificity

    Article • September 2026, openRxiv

    Dr. Jiansheng Jiang

  2. Unlocking Innate Antitumor Immunity by Targeting HLA-Mediated Immune Tolerance

    Article • Communications Biology, February 2026, Springer Science + Business Media

    Dr. Jiansheng Jiang, Dr. Abir K. Panda

  3. Antibodies Unlock the Immune System to Attack Cancer by Blocking Self-Protection Signals

    Article • Cancer Immunology Research, October 2025, American Association for Cancer Research (AACR)

    Dr. Jiansheng Jiang, Dr. Abir K. Panda

  4. Chaperone-mediated MHC-I peptide exchange in antigen presentation

    Article • IUCrJ, April 2024, International Union of Crystallography

    Dr. Jiansheng Jiang

  5. Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction

    Article • The Journal of Immunology, March 2024, The American Association of Immunologists

    Dr. Jiansheng Jiang

  6. Experimental structures of antibody/MHC-I complexes reveal details of epitopes overlooked by computational prediction

    Article • December 2023, Cold Spring Harbor Laboratory Press

    Dr. Jiansheng Jiang

  7. SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

    Article • Communications Biology, September 2023, Springer Science + Business Media

    Dr. Jiansheng Jiang

  8. Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond

    Article • Frontiers in Immunology, June 2023, Frontiers

    Dr. Jiansheng Jiang

  9. SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

    Article • May 2023, Research Square

    Dr. Jiansheng Jiang

  10. Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation

    Article • Nature Communications, September 2022, Springer Science + Business Media

    Dr. Jiansheng Jiang

  11. Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity

    Article • Frontiers in Immunology, April 2022, Frontiers

    Dr. Jiansheng Jiang

  12. Mucus sialylation determines intestinal host-commensal homeostasis

    Article • Cell, March 2022, Elsevier

    Dr. Jiansheng Jiang

  13. Structures of synthetic nanobody–SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction

    Article • Journal of Biological Chemistry, October 2021, Elsevier

    Dr. Jiansheng Jiang

  14. Structures of synthetic nanobody–SARS-CoV-2–RBD complexes reveal distinct sites of interaction and recognition of variants

    Article • June 2021, Research Square

    Dr. Jiansheng Jiang

  15. Structural mechanism of DNA recognition by the p204 HIN domain

    Article • Nucleic Acids Research, February 2021, Oxford University Press (OUP)

    Dr. Jiansheng Jiang

  16. Synthetic nanobody–SARS-CoV-2 receptor-binding domain structures identify distinct epitopes

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Dr. Jiansheng Jiang

  17. Structural and dynamic studies of TAPBPR and Tapasin reveal the mechanism of peptide loading of MHC-I molecules

    Article • Current Opinion in Immunology, June 2020, Elsevier

    Dr. Jiansheng Jiang

  18. Structure determination of the CAMP factor ofStreptococcus agalactiaewith the aid of an MBP tag and insights into membrane-surface attachment

    Article • Acta Crystallographica Section D Structural Biology, July 2019, International Union of Crystallography

    Dr. Jiansheng Jiang

  19. MHC‐restricted Ag85B‐specific CD8+ T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice

    Article • European Journal of Immunology, June 2019, Wiley

    Dr. Jiansheng Jiang

  20. Structural aspects of chaperone-mediated peptide loading in the MHC-I antigen presentation pathway

    Article • Critical Reviews in Biochemistry and Molecular Biology, March 2019, Taylor & Francis

    Dr. Jiansheng Jiang

  21. MHC Molecules, T cell Receptors, Natural Killer Cell Receptors, and Viral Immunoevasins—Key Elements of Adaptive and Innate Immunity

    Article • January 2019, Springer Science + Business Media

    Dr. Jiansheng Jiang

  22. Structure and Function of Molecular Chaperones that Govern Immune Peptide Loading

    Article • January 2019, Springer Science + Business Media

    Dr. Jiansheng Jiang

  23. Revisit of Reconstituted 30-nm Nucleosome Arrays Reveals an Ensemble of Dynamic Structures

    Article • Journal of Molecular Biology, September 2018, Elsevier

    Dr. Jiansheng Jiang

  24. The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

    Article • Frontiers in Immunology, July 2018, Frontiers

    Dr. Jiansheng Jiang

  25. Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle

    Article • Nature Chemical Biology, July 2018, Springer Science + Business Media

    Dr. Jiansheng Jiang

  26. Functional and structural characterization of zebrafish ASC

    Article • FEBS Journal, June 2018, Wiley

    Dr. Jiansheng Jiang

  27. Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity

    Article • The Journal of Immunology, March 2018, The American Association of Immunologists

    Dr. Jiansheng Jiang

  28. Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction

    Article • PLOS One, January 2018, PLOS

    Dr. Jiansheng Jiang

  29. Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen presentation

    Article • Science, November 2017, American Association for the Advancement of Science

    Dr. Jiansheng Jiang

  30. An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role

    Article • Nature Communications, May 2017, Springer Science + Business Media

    Dr. Jiansheng Jiang

  31. Design of an expression system to enhance MBP-mediated crystallization

    Article • Scientific Reports, January 2017, Springer Science + Business Media

    Dr. Jiansheng Jiang

  32. Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing

    Article • Proceedings of the National Academy of Sciences, February 2016, Proceedings of the National Academy of Sciences

    Dr. Jiansheng Jiang

  33. Structural Mechanisms of Nucleosome Recognition by Linker Histones

    Article • Molecular Cell, August 2015, Elsevier

    Dr. Jiansheng Jiang

  34. RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

    Article • Journal of Experimental Medicine, April 2014, Rockefeller University Press

    Dr. Jiansheng Jiang

  35. The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer

    Article • Molecular Cell, February 2014, Elsevier

    Dr. Jiansheng Jiang

  36. Novel complex MAD phasing and RNase H structural insights using selenium oligonucleotides

    Article • Acta Crystallographica Section D Biological Crystallography, January 2014, International Union of Crystallography

    Dr. Jiansheng Jiang

  37. Crystal Structures of the Toll/Interleukin-1 Receptor (TIR) Domains from the Brucella Protein TcpB and Host Adaptor TIRAP Reveal Mechanisms of Molecular Mimicry

    Article • Journal of Biological Chemistry, January 2014, Elsevier

    Dr. Jiansheng Jiang

  38. RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

    Article • Journal of Cell Biology, October 2013, Rockefeller University Press

    Dr. Jiansheng Jiang

  39. RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

    Article • Journal of Experimental Medicine, September 2013, Rockefeller University Press

    Dr. Jiansheng Jiang

  40. Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2013, International Union of Crystallography

    Dr. Jiansheng Jiang

  41. A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-C

    Article • Science, May 2013, American Association for the Advancement of Science

    Dr. Jiansheng Jiang

  42. Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly

    Article • Journal of Biological Chemistry, May 2013, Elsevier

    Dr. Jiansheng Jiang

  43. The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2013, International Union of Crystallography

    Dr. Jiansheng Jiang

  44. Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase‐1

    Article • Proteins Structure Function and Bioinformatics, April 2013, Wiley

    Dr. Jiansheng Jiang

  45. Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli

    Article • Proceedings of the National Academy of Sciences, April 2013, Proceedings of the National Academy of Sciences

    Dr. Jiansheng Jiang

  46. Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B

    Article • Structure, May 2012, Elsevier

    Dr. Jiansheng Jiang

  47. Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

    Article • Immunity, April 2012, Elsevier

    Professor Eicke Latz, Dr. Jiansheng Jiang

  48. The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release

    Article • Structure, October 2011, Elsevier

    Dr. Jiansheng Jiang

  49. Synthesis and Crystallographic Analysis of 5-Se-Thymidine DNAs

    Article • Organic Letters, May 2009, American Chemical Society (ACS)

    Dr. Jiansheng Jiang

  50. Derivatization of DNAs with selenium at 6-position of guanine for function and crystal structure studies

    Article • Nucleic Acids Research, November 2008, Oxford University Press (OUP)

    Dr. Jiansheng Jiang

  51. 218 Mechanism of TOLL/IL-1 receptor domain dimerization and signaling revealed by a crystal structure of the MYD88

    Article • Cytokine, September 2008, Elsevier

    Dr. Jiansheng Jiang

  52. Oxygen Replacement with Selenium at the Thymidine 4-Position for the Se Base Pairing and Crystal Structure Studies

    Article • Journal of the American Chemical Society, March 2007, American Chemical Society (ACS)

    Dr. Jiansheng Jiang

  53. Synthesis of a 2‘-Se-thymidine Phosphoramidite and Its Incorporation into Oligonucleotides for Crystal Structure Study

    Article • Organic Letters, January 2007, American Chemical Society (ACS)

    Dr. Jiansheng Jiang

  54. Selenium derivatization of nucleic acids for crystallography

    Article • Nucleic Acids Research, December 2006, Oxford University Press (OUP)

    Dr. Jiansheng Jiang

  55. Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel

    Article • Journal of Biological Chemistry, January 2006, Elsevier

    Dr. Jiansheng Jiang

  56. Protein Data Bank depositions from synchrotron sources

    Article • Journal of Synchrotron Radiation, June 2004, International Union of Crystallography

    Dr. Jiansheng Jiang

  57. Crystallization and preliminary crystallographic analysis of theEscherichia coliwater channel AqpZ

    Article • Acta Crystallographica Section D Biological Crystallography, February 2004, International Union of Crystallography

    Dr. Jiansheng Jiang

  58. Structural genomics: A pipeline for providing structures for the biologist

    Article • Protein Science, April 2002, Wiley

    Dr. Jiansheng Jiang

  59. AutoDep: a web-based system for deposition and validation of macromolecular structural information

    Article • Acta Crystallographica Section D Biological Crystallography, July 2000, International Union of Crystallography

    Dr. Jiansheng Jiang

  60. Deposition of structure factors at the Protein Data Bank

    Article • Acta Crystallographica Section D Biological Crystallography, January 1999, International Union of Crystallography

    Dr. Jiansheng Jiang

  61. Article • Genetica, January 1999, Springer Science + Business Media

    Dr. Jiansheng Jiang

  62. Protein Data Bank (PDB): Database of Three-Dimensional Structural Information of Biological Macromolecules

    Article • Acta Crystallographica Section D Biological Crystallography, November 1998, International Union of Crystallography

    Dr. Jiansheng Jiang

  63. Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

    Article • Acta Crystallographica Section D Biological Crystallography, September 1998, International Union of Crystallography

    Dr. Jiansheng Jiang

  64. Protein Hydration Observed by X-ray Diffraction

    Article • Journal of Molecular Biology, October 1994, Elsevier

    Dr. Jiansheng Jiang