All Stories

  1. Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes

    Article • PLoS Pathogens, July 2022, PLOS

    Professor Jianming Hu

  2. Host cell-dependent late entry step as determinant of hepatitis B virus infection

    Article • PLoS Pathogens, June 2022, PLOS

    Professor Jianming Hu

  3. Multiple roles of PP2A binding motif in hepatitis B virus core linker and PP2A in regulating core phosphorylation state and viral replication

    Article • PLoS Pathogens, January 2021, PLOS

    Professor Jianming Hu

  4. Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation

    Article • PLoS Pathogens, March 2020, PLOS

    Professor Jianming Hu

  5. Common and Distinct Capsid and Surface Protein Requirements for Secretion of Complete and Genome-Free Hepatitis B Virions

    Article • Journal of Virology, May 2018, ASM Journals

    Professor Jianming Hu

  6. Identification of an Intermediate in Hepatitis B Virus Covalently Closed Circular (CCC) DNA Formation and Sensitive and Selective CCC DNA Detection

    Article • Journal of Virology, June 2017, ASM Journals

    Professor Jianming Hu

  7. Capsid Phosphorylation State and Hepadnavirus Virion Secretion

    Article • Journal of Virology, February 2017, ASM Journals

    Professor Jianming Hu

  8. Cell-Free Hepatitis B Virus Capsid Assembly Dependent on the Core Protein C-Terminal Domain and Regulated by Phosphorylation

    Article • Journal of Virology, April 2016, ASM Journals

    Professor Jianming Hu

  9. Viral DNA-Dependent Induction of Innate Immune Response to Hepatitis B Virus in Immortalized Mouse Hepatocytes

    Article • Journal of Virology, October 2015, ASM Journals

    Professor Jianming Hu

  10. Alteration of Mature Nucleocapsid and Enhancement of Covalently Closed Circular DNA Formation by Hepatitis B Virus Core Mutants Defective in Complete-Virion Formation

    Article • Journal of Virology, July 2015, ASM Journals

    Professor Jianming Hu

  11. Hepatitis B Virus Covalently Closed Circular DNA Formation in Immortalized Mouse Hepatocytes Associated with Nucleocapsid Destabilization

    Article • Journal of Virology, June 2015, ASM Journals

    Professor Jianming Hu

  12. Regulation of Multiple Stages of Hepadnavirus Replication by the Carboxyl-Terminal Domain of Viral Core Protein in trans

    Article • Journal of Virology, December 2014, ASM Journals

    Professor Jianming Hu

  13. Sequences in the terminal protein and reverse transcriptase domains of the hepatitis B virus polymerase contribute to RNA binding and encapsidation

    Article • Journal of Viral Hepatitis, January 2014, Wiley

    Professor Jianming Hu

  14. Comparative Analysis of Hepatitis B Virus Polymerase Sequences Required for Viral RNA Binding, RNA Packaging, and Protein Priming

    Article • Journal of Virology, November 2013, ASM Journals

    Professor Jianming Hu

  15. In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase

    Article • Journal of Virology, October 2013, ASM Journals

    Professor Jianming Hu

  16. Noncompetitive Inhibition of Hepatitis B Virus Reverse Transcriptase Protein Priming and DNA Synthesis by the Nucleoside Analog Clevudine

    Article • Antimicrobial Agents and Chemotherapy, October 2013, ASM Journals

    Professor Jianming Hu

  17. Maturation-Associated Destabilization of Hepatitis B Virus Nucleocapsid

    Article • Journal of Virology, August 2013, ASM Journals

    Professor Jianming Hu

  18. Noncompetitive Inhibition of Hepatitis B Virus Reverse Transcriptase Protein Priming and DNA Synthesis by the Nucleoside Analog Clevudine

    Article • Antimicrobial Agents and Chemotherapy, June 2013, ASM Journals

    Professor Jianming Hu

  19. Hepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral intervention

    Article • Emerging Microbes & Infections, January 2013, Taylor & Francis

    Professor Jianming Hu

  20. Protein-Primed Terminal Transferase Activity of Hepatitis B Virus Polymerase

    Article • Journal of Virology, December 2012, ASM Journals

    Professor Jianming Hu

  21. Cyclin-Dependent Kinase 2 Phosphorylates S/T-P Sites in the Hepadnavirus Core Protein C-Terminal Domain and Is Incorporated into Viral Capsids

    Article • Journal of Virology, September 2012, ASM Journals

    Professor Jianming Hu

  22. TP-RT Domain Interactions of Duck Hepatitis B Virus Reverse Transcriptase in cis and in trans during Protein-Primed Initiation of DNA Synthesis In Vitro

    Article • Journal of Virology, April 2012, ASM Journals

    Professor Jianming Hu

  23. Phosphorylation State-Dependent Interactions of Hepadnavirus Core Protein with Host Factors

    Article • PLoS ONE, December 2011, PLOS

    Professor Jianming Hu

  24. A Theoretical Model for the Dynamic Structure of Hepatitis B Nucleocapsid

    Article • Biophysical Journal, November 2011, Elsevier

    Professor Jianming Hu

  25. Secretion of Genome-Free Hepatitis B Virus – Single Strand Blocking Model for Virion Morphogenesis of Para-retrovirus

    Article • PLoS Pathogens, September 2011, PLOS

    Professor Jianming Hu

  26. Cryptic Protein Priming Sites in Two Different Domains of Duck Hepatitis B Virus Reverse Transcriptase for Initiating DNA Synthesis In Vitro

    Article • Journal of Virology, May 2011, ASM Journals

    Professor Jianming Hu

  27. An interdomain RNA binding site on the hepadnaviral polymerase that is essential for reverse transcription

    Article • Virology, July 2009, Elsevier

    Professor Jianming Hu

  28. trans-Complementation of HBV rtM204I mutant replication by HBV wild-type polymerase

    Article • Virology, May 2009, Elsevier

    Professor Jianming Hu

  29. RNA-protein interactions in hepadnavirus reverse transcription

    Article • Frontiers in Bioscience, January 2009, Frontiers in Bioscience

    Professor Jianming Hu

  30. Hepatitis B virus–cell interactions and pathogenesis

    Article • Journal of Cellular Physiology, January 2008, Wiley

    Professor Jianming Hu

  31. HIV–HBV and HIV–HCV Coinfection and Liver Cancer Development

    Article • January 2007, Springer Science + Business Media

    Professor Jianming Hu

  32. Hepatitis B Virus Reverse Transcriptase and ε RNA Sequences Required for Specific Interaction In Vitro

    Article • Journal of Virology, March 2006, ASM Journals

    Professor Jianming Hu

  33. Requirement of Heat Shock Protein 90 for Human Hepatitis B Virus Reverse Transcriptase Function

    Article • Journal of Virology, December 2004, ASM Journals

    Professor Jianming Hu

  34. Therapy for chronic hepatitis B: the earlier, the better?

    Article • Trends in Microbiology, October 2004, Elsevier

    Professor Jianming Hu

  35. Reconstitution of a Functional Duck Hepatitis B Virus Replication Initiation Complex from Separate Reverse Transcriptase Domains Expressed in Escherichia coli

    Article • Journal of Virology, August 2001, ASM Journals

    Professor Jianming Hu

  36. In Vitro Reconstitution of a Functional Duck Hepatitis B Virus Reverse Transcriptase: Posttranslational Activation by Hsp90

    Article • Journal of Virology, December 2000, ASM Journals

    Professor Jianming Hu

  37. Why are hepadnaviruses DNA and not RNA viruses?

    Article • Trends in Microbiology, November 1997, Elsevier

    Professor Jianming Hu

  38. RNA Signals That Control DNA Replication in Hepadnaviruses

    Article • Seminars in Virology, January 1997, Elsevier

    Professor Jianming Hu

  39. Mutagenesis of a Hepatitis B Virus Reverse Transcriptase Yields Temperature-Sensitive Virus

    Article • Virology, August 1996, Elsevier

    Professor Jianming Hu

  40. Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase.

    Article • Proceedings of the National Academy of Sciences, February 1996, Proceedings of the National Academy of Sciences

    Professor Jianming Hu

  41. Studying DHBV Polymerase by In Vitro Transcription and Translation

    Article • Springer Science + Business Media

    Professor Jianming Hu