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  1. Pharmacokinetics and pharmacodynamics of antibacterial peptide NZX in Staphylococcus aureus mastitis mouse model

    Article • Applied Microbiology and Biotechnology, March 2024, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  2. Polylactic Glycolic Acid-Mediated Delivery of Plectasin Derivative NZ2114 in Staphylococcus epidermidis Biofilms

    Article • Antibiotics, February 2024, MDPI AG

    Professor and senior PI Jianhua WANG

  3. Efficiency of NZ2114 on Superficial Pyoderma Infected with Staphylococcus pseudintermedius

    Article • Pharmaceuticals, February 2024, MDPI AG

    Professor and senior PI Jianhua WANG

  4. Expression and characterization of the new antimicrobial peptide AP138L-arg26 anti Staphylococcus aureus

    Article • Applied Microbiology and Biotechnology, January 2024, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  5. Plectasin: from evolution to truncation, expression, and better druggability

    Article • Frontiers in Microbiology, December 2023, Frontiers

    Professor and senior PI Jianhua WANG

  6. High-Yield Preparation of American Oyster Defensin (AOD) via a Small and Acidic Fusion Tag and Its Functional Characterization

    Article • Marine Drugs, December 2023, MDPI AG

    Professor and senior PI Jianhua WANG

  7. A cleavable chimeric peptide with targeting and killing domains enhances LPS neutralization and antibacterial properties against multi-drug resistant E. coli

    Article • Communications Biology, November 2023, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  8. Perspective: A proposal on solutions of modern supply chain construction for lactoferrin

    Article • Journal of Dairy Science, November 2023, American Dairy Science Association

    Professor and senior PI Jianhua WANG

  9. Site Mutation Improves the Expression and Antimicrobial Properties of Fungal Defense

    Article • Antibiotics, August 2023, MDPI AG

    Professor and senior PI Jianhua WANG

  10. Lactoferrin, a Great Wall of host-defence?

    Article • BioMetals, April 2023, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  11. Molecular Modification of Kex2 P1’ Site Enhances Expression and Druggability of Fungal Defensin

    Article • Antibiotics, April 2023, MDPI AG

    Professor and senior PI Jianhua WANG

  12. Thinking on the Construction of Antimicrobial Peptide Databases: Powerful Tools for the Molecular Design and Screening

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Professor and senior PI Jianhua WANG

  13. Editorial: Community series in antimicrobial peptides: Molecular design, structure function relationship and biosynthesis optimization

    Article • Frontiers in Microbiology, January 2023, Frontiers

    Professor and senior PI Jianhua WANG

  14. D1018 with higher stability and excellent lipopolysaccharide binding affinity has potent anti-bacterial and anti-inflammatory activity

    Article • Frontiers in Microbiology, December 2022, Frontiers

    Professor and senior PI Jianhua WANG

  15. Effects of dietary supplementation of bovine lactoferrin on growth performance, immune function and intestinal health in weaning piglets

    Article • BioMetals, November 2022, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  16. Effect of NZ2114 against Streptococcus dysgalactiae biofilms and its application in murine mastitis model

    Article • Frontiers in Microbiology, September 2022, Frontiers

    Professor and senior PI Jianhua WANG

  17. Pharmacokinetics and Pharmacodynamics of Fungal Defensin NZX Against Staphylococcus aureus-Induced Mouse Peritonitis Model

    Article • Frontiers in Microbiology, June 2022, Frontiers

    Professor and senior PI Jianhua WANG

  18. C-terminal mini-PEGylation of a marine peptide N6 had potent antibacterial and anti-inflammatory properties against Escherichia coli and Salmonella strains in vitro and in vivo

    Article • BMC Microbiology, May 2022, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  19. The Outer Membrane Proteins and Their Synergy Triggered the Protective Effects against Pathogenic Escherichia coli

    Article • Microorganisms, May 2022, MDPI AG

    Professor and senior PI Jianhua WANG

  20. Antibacterial peptide NZ2114-loaded hydrogel accelerates Staphylococcus aureus-infected wound healing

    Article • Applied Microbiology and Biotechnology, May 2022, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  21. In Vitro Pharmacodynamics and Bactericidal Mechanism of Fungal Defensin-Derived Peptides NZX and P2 against Streptococcus agalactiae

    Article • Microorganisms, April 2022, MDPI AG

    Professor and senior PI Jianhua WANG

  22. Editorial: Antimicrobial Peptides: Molecular Design, Structure-Function Relationship, and Biosynthesis Optimization

    Article • Frontiers in Microbiology, April 2022, Frontiers

    Professor and senior PI Jianhua WANG

  23. Fascaplysin derivatives binding to DNA via unique cationic five-ring coplanar backbone showed potent antimicrobial/antibiofilm activity against MRSA in vitro and in vivo

    Article • European Journal of Medicinal Chemistry, February 2022, Elsevier

    Professor and senior PI Jianhua WANG

  24. Resistance response to Arenicin derivatives in Escherichia coli

    Article • Applied Microbiology and Biotechnology, December 2021, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  25. A study on fungal defensin against multidrug-resistant Clostridium perfringens and its treatment on infected poultry

    Article • Applied Microbiology and Biotechnology, September 2021, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  26. Fatty acid modified-antimicrobial peptide analogues with potent antimicrobial activity and topical therapeutic efficacy against Staphylococcus hyicus

    Article • Applied Microbiology and Biotechnology, July 2021, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  27. Design and Pharmacodynamics of Recombinant Fungus Defensin NZL with Improved Activity against Staphylococcus hyicus In Vitro and In Vivo

    Article • International Journal of Molecular Sciences, May 2021, MDPI AG

    Professor and senior PI Jianhua WANG

  28. The Pharmacodynamics Study of Insect Defensin DLP4 Against Toxigenic Staphylococcus hyicus ACCC 61734 in Vitro and Vivo

    Article • Frontiers in Cellular and Infection Microbiology, May 2021, Frontiers

    Professor and senior PI Jianhua WANG

  29. Design and High Expression of Non-glycosylated Lysostaphins in Pichia pastoris and Their Pharmacodynamic Study

    Article • Frontiers in Microbiology, March 2021, Frontiers

    Professor and senior PI Jianhua WANG

  30. Marine Peptide-N6NH2 and Its Derivative-GUON6NH2 Have Potent Antimicrobial Activity Against Intracellular Edwardsiella tarda in vitro and in vivo

    Article • Frontiers in Microbiology, March 2021, Frontiers

    Professor and senior PI Jianhua WANG

  31. Potent intracellular antibacterial activity of a marine peptide-N6NH2 and its D-enantiomer against multidrug-resistant Aeromonas veronii

    Article • Applied Microbiology and Biotechnology, February 2021, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  32. A prospective on multiple biological activities of lactoferrin contributing to piglet welfare

    Article • Biochemistry and Cell Biology, February 2021, Canadian Science Publishing

    Professor and senior PI Jianhua WANG

  33. A recombinant fungal defensin-like peptide-P2 combats Streptococcus dysgalactiae and biofilms

    Article • Applied Microbiology and Biotechnology, February 2021, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  34. Dual Antibacterial Activities and Biofilm Eradication of a Marine Peptide-N6NH2 and Its Analogs against Multidrug-Resistant Aeromonas veronii

    Article • International Journal of Molecular Sciences, December 2020, MDPI AG

    Professor and senior PI Jianhua WANG

  35. Improved Stability and Activity of a Marine Peptide-N6NH2 against Edwardsiella tarda and Its Preliminary Application in Fish

    Article • Marine Drugs, December 2020, MDPI AG

    Professor and senior PI Jianhua WANG

  36. A Review on the Use of Antimicrobial Peptides to Combat Porcine Viruses

    Article • Antibiotics, November 2020, MDPI AG

    Professor and senior PI Jianhua WANG

  37. A critical review of antibiotic resistance in probiotic bacteria

    Article • Food Research International, October 2020, Elsevier

    Professor and senior PI Jianhua WANG

  38. Recent progress of bacterial FtsZ inhibitors with a focus on peptides

    Article • FEBS Journal, August 2020, Wiley

    Professor and senior PI Jianhua WANG

  39. Therapeutic potential of a designed CSαβ peptide ID13 in Staphylococcus aureus-induced endometritis of mice

    Article • Applied Microbiology and Biotechnology, June 2020, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  40. An Enhanced Variant Designed From DLP4 Cationic Peptide Against Staphylococcus aureus CVCC 546

    Article • Frontiers in Microbiology, June 2020, Frontiers

    Professor and senior PI Jianhua WANG

  41. Recombinant of the Staphylococcal Bacteriophage Lysin CHAPk and Its Elimination against Streptococcus agalactiae Biofilms

    Article • Microorganisms, February 2020, MDPI AG

    Professor and senior PI Jianhua WANG

  42. Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli

    Article • Communications Biology, January 2020, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  43. A new high-yielding antimicrobial peptide NZX and its antibacterial activity against Staphylococcus hyicus in vitro/vivo

    Article • Applied Microbiology and Biotechnology, January 2020, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  44. Recent progress in preparation and agricultural application of microcapsules

    Article • Journal of Biomedical Materials Research Part A, June 2019, Wiley

    Professor and senior PI Jianhua WANG

  45. Synthesis and characterization of calcium phosphorylated inulin complex as a new source of enriched calcium supplement with prebiotic effect in food

    Article • Food Science and Technology, June 2019, FapUNIFESP (SciELO)

    Professor and senior PI Jianhua WANG

  46. Internalization, distribution, and activity of peptide H2 against the intracellular multidrug-resistant bovine mastitis-causing bacterium Staphylococcus aureus

    Article • Scientific Reports, May 2019, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  47. A recombinant fungal defensin-like peptide-P2 combats multidrug-resistant Staphylococcus aureus and biofilms

    Article • Applied Microbiology and Biotechnology, April 2019, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  48. In vitro/vivo Mechanism of Action of MP1102 With Low/Nonresistance Against Streptococcus suis Type 2 Strain CVCC 3928

    Article • Frontiers in Cellular and Infection Microbiology, February 2019, Frontiers

    Professor and senior PI Jianhua WANG

  49. Improved Antibacterial Activity of the Marine Peptide N6 against Intracellular Salmonella Typhimurium by Conjugating with the Cell-Penetrating Peptide Tat11 via a Cleavable Linker

    Article • Journal of Medicinal Chemistry, August 2018, American Chemical Society (ACS)

    Professor and senior PI Jianhua WANG

  50. Increased intracellular activity of MP1102 and NZ2114 against Staphylococcus aureus in vitro and in vivo

    Article • Scientific Reports, March 2018, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  51. A review of the design and modification of lactoferricins and their derivatives

    Article • BioMetals, February 2018, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  52. Recent Advances in Antibacterial and Antiendotoxic Peptides or Proteins from Marine Resources

    Article • Marine Drugs, February 2018, MDPI AG

    Professor and senior PI Jianhua WANG

  53. Improved antibacterial activity of a marine peptide-N2 against intracellular Salmonella typhimurium by conjugating with cell-penetrating peptides-bLFcin 6 /Tat 11

    Article • European Journal of Medicinal Chemistry, February 2018, Elsevier

    Professor and senior PI Jianhua WANG

  54. Effective Antimicrobial Activity of Plectasin-Derived Antimicrobial Peptides against Staphylococcus aureus Infection in Mammary Glands

    Article • Frontiers in Microbiology, December 2017, Frontiers

    Professor and senior PI Jianhua WANG

  55. Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus

    Article • Scientific Reports, September 2017, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  56. Mode of action of plectasin-derived peptides against gas gangrene-associated Clostridium perfringens type A

    Article • PLoS ONE, September 2017, PLOS

    Professor and senior PI Jianhua WANG

  57. Deleting the first disulphide bond in an arenicin derivative enhances its expression in Pichia pastoris

    Article • Letters in Applied Microbiology, August 2017, Oxford University Press (OUP)

    Professor and senior PI Jianhua WANG

  58. Escherichia coli outer membrane protein F (OmpF): an immunogenic protein induces cross-reactive antibodies against Escherichia coli and Shigella

    Article • AMB Express, July 2017, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  59. Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis

    Article • Scientific Reports, June 2017, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  60. Research advances on plectasin and its derivatives as new potential antimicrobial candidates

    Article • Process Biochemistry, May 2017, Elsevier

    Professor and senior PI Jianhua WANG

  61. Killing of Staphylococcus aureus and Salmonella enteritidis and neutralization of lipopolysaccharide by 17-residue bovine lactoferricins: improved activity of Trp/Ala-containing molecules

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  62. Design and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus

    Article • AMB Express, February 2017, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  63. In vitro and in vivo antibacterial effect of NZ2114 against Streptococcus suis type 2 infection in mice peritonitis models

    Article • AMB Express, February 2017, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  64. Research and development on lactoferrin and its derivatives in China from 2011–2015

    Article • Biochemistry and Cell Biology, February 2017, Canadian Science Publishing

    Professor and senior PI Jianhua WANG

  65. Combined Systems Approaches Reveal a Multistage Mode of Action of a Marine Antimicrobial Peptide against Pathogenic Escherichia coli and Its Protective Effect against Bacterial Peritonitis and Endotoxemia

    Article • Antimicrobial Agents and Chemotherapy, January 2017, ASM Journals

    Professor and senior PI Jianhua WANG

  66. Enhancement of Nutritional and Antioxidant Properties of Peanut Meal by Bio-modification with Bacillus licheniformis

    Article • Applied Biochemistry and Biotechnology, June 2016, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  67. Modification and characterization of a new recombinant marine antimicrobial peptide N2

    Article • Process Biochemistry, June 2016, Elsevier

    Professor and senior PI Jianhua WANG

  68. In silico analysis and recombinant expression of BamA protein as a universal vaccine against Escherichia coli in mice

    Article • Applied Microbiology and Biotechnology, March 2016, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  69. Mechanism of action of a novel recombinant peptide, MP1102, against Clostridium perfringens type C

    Article • Applied Microbiology and Biotechnology, February 2016, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  70. Paving the way to construct a new vaccine against Escherichia coli from its recombinant outer membrane protein C via a murine model

    Article • Process Biochemistry, August 2015, Elsevier

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  71. Multiple copies of the target gene enhances plectasin secretion in Pichia pastoris X-33

    Article • Process Biochemistry, April 2015, Elsevier

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  72. Detection of genetically modified crops using multiplex asymmetric polymerase chain reaction and asymmetric hyperbranched rolling circle amplification coupled with reverse dot blot

    Article • Food Chemistry, April 2015, Elsevier

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  73. Optimization of expression conditions for a novel NZ2114-derived antimicrobial peptide-MP1102 under the control of the GAP promoter in Pichia pastoris X-33

    Article • BMC Microbiology, March 2015, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  74. GAP-initiated constitutive expression of a novel plectasin-derived peptide MP1106 by Pichia pastoris and its activity against Streptococcus suis

    Article • Process Biochemistry, February 2015, Elsevier

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  75. In vitro and in vivo characterization of a new recombinant antimicrobial peptide, MP1102, against methicillin-resistant Staphylococcus aureus

    Article • Applied Microbiology and Biotechnology, January 2015, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  76. Recombinant outer membrane protein A induces a protective immune response against Escherichia coli infection in mice

    Article • Applied Microbiology and Biotechnology, January 2015, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  77. Saccharomyces boulardii prevention of the hepatic injury induced by Salmonella Enteritidis infection

    Article • Canadian Journal of Microbiology, October 2014, Canadian Science Publishing

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  78. Design and recombination expression of a novel plectasin-derived peptide MP1106 and its properties against Staphylococcus aureus

    Article • Applied Microbiology and Biotechnology, September 2014, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  79. Biotechnical paving of recombinant enterocin A as the candidate of anti-Listeriaagent

    Article • BMC Microbiology, August 2014, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  80. Mechanism of action of the tri-hybrid antimicrobial peptide LHP7 from lactoferricin, HP and plectasin on Staphylococcus aureus

    Article • BioMetals, July 2014, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  81. A dual mechanism involved in membrane and nucleic acid disruption of AvBD103b, a new avian defensin from the king penguin, against Salmonella enteritidis CVCC3377

    Article • Applied Microbiology and Biotechnology, July 2014, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  82. Candidacidal mechanism of the arenicin-3-derived peptide NZ17074 from Arenicola marina

    Article • Applied Microbiology and Biotechnology, May 2014, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  83. Recombinant production of the antimicrobial peptide NZ17074 inPichia pastorisusing SUMO3 as a fusion partner

    Article • Letters in Applied Microbiology, April 2014, Wiley

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  84. Rapid cloning, expression and purification of a novel high-activity alkaline phosphatase with detoxification of lipopolysaccharide

    Article • Process Biochemistry, March 2014, Elsevier

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  85. Influence of Different Processing Treatments on the Detectability of Nucleic Acid and Protein Targets in Transgenic Soybean Meal

    Article • Applied Biochemistry and Biotechnology, February 2014, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  86. High expression of a plectasin-derived peptide NZ2114 in Pichia pastoris and its pharmacodynamics, postantibiotic and synergy against Staphylococcus aureus

    Article • Applied Microbiology and Biotechnology, April 2013, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  87. Erratum to: Design, expression, and characterization of a novel targeted plectasin against methicillin-resistant Staphylococcus aureus

    Article • Applied Microbiology and Biotechnology, March 2013, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  88. Design, expression and characterization of the hybrid antimicrobial peptide LHP7, connected by a flexible linker, against Staphylococcus and Streptococcus

    Article • Process Biochemistry, March 2013, Elsevier

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  89. Detection of the Soybean Allergenic Protein Gly m Bd 28K by an Indirect Enzyme-Linked Immunosorbent Assay

    Article • Journal of Agricultural and Food Chemistry, January 2013, American Chemical Society (ACS)

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  90. DNA Degradation of Genetically Modified Cottonseed Meal During Feed Processing

    Article • Applied Biochemistry and Biotechnology, November 2012, Springer Science + Business Media

    Professor and senior PI Jianhua WANG

  91. Design, expression, and characterization of a novel targeted plectasin against methicillin-resistant Staphylococcus aureus

    Article • Applied Microbiology and Biotechnology, October 2012, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  92. Expression of the soybean allergenic protein P34 in Escherichia coli and its indirect ELISA detection method

    Article • Applied Microbiology and Biotechnology, March 2012, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  93. Characterization of recombinant plectasin: Solubility, antimicrobial activity and factors that affect its activity

    Article • Process Biochemistry, May 2011, Elsevier

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG

  94. Construction of a reference plasmid molecule containing eight targets for the detection of genetically modified crops

    Article • Applied Microbiology and Biotechnology, February 2011, Springer Science + Business Media

    Professor Jianhua WANG, Professor and senior PI Jianhua WANG