All Stories

  1. Metabolic activation and cytotoxicity of metaxalone mediated by cytochrome P450 enzymes and sulfotransferases

    Article • Chemico-Biological Interactions, September 2023, Elsevier

    Professor Jiang Zheng

  2. Evidence for the Metabolic Activation of Deferasirox In Vitro and In Vivo

    Article • Chemical Research in Toxicology, July 2023, American Chemical Society (ACS)

    Professor Jiang Zheng

  3. Recent advances in mass spectrometry-based spatially resolved molecular imaging of drug disposition and metabolomics

    Article • Drug Metabolism and Disposition, June 2023, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  4. Difference in hepatotoxicity of furan-containing components in cortex dictamni correlates the efficiency of their metabolic activation

    Article • Phytomedicine, June 2023, Elsevier

    Professor Jiang Zheng

  5. Reduction of emodin-8-O-ß-D-glucoside content participates in processing-based detoxification of polygoni multiflori radix

    Article • Phytomedicine, June 2023, Elsevier

    Professor Jiang Zheng

  6. DNA damage and up-regulation of PARP-1 induced by columbin in vitro and in vivo

    Article • Toxicology Letters, April 2023, Elsevier

    Professor Jiang Zheng

  7. Formation of RNA adducts resulting from metabolic activation of spice ingredient safrole mediated by P450 enzymes and sulfotransferases

    Article • Food and Chemical Toxicology, April 2023, Elsevier

    Professor Jiang Zheng

  8. Immunochemical and LC–MS/MS Detection of Protein Adduction Resulting from Metabolic Activation of Columbin In Vitro and In Vivo

    Article • Chemical Research in Toxicology, March 2023, American Chemical Society (ACS)

    Professor Jiang Zheng

  9. Mechanistic Study of Xanthotoxin-Mediated Inactivation of CYP1A2 and Related Drug–Drug Interaction with Tacrine

    Article • Chemical Research in Toxicology, March 2023, American Chemical Society (ACS)

    Professor Jiang Zheng

  10. Effects of xenobiotics on CYP1 enzyme-mediated biotransformation and bioactivation of estradiol

    Article • Drug Metabolism Reviews, February 2023, Taylor & Francis

    Professor Jiang Zheng

  11. OAT3 Participates in Drug–Drug Interaction between Bentysrepinine and Entecavir through Interactions with M8—A Metabolite of Bentysrepinine—In Rats and Humans In Vitro

    Article • Molecules, February 2023, MDPI AG

    Professor Jiang Zheng

  12. In Vitro and In Vivo Metabolic Activation of Tolterodine Mediated by CYP3A

    Article • Chemical Research in Toxicology, February 2023, American Chemical Society (ACS)

    Professor Jiang Zheng

  13. Inflammation Intensifies Monocrotaline-Induced Liver Injury

    Article • Journal of Agricultural and Food Chemistry, February 2023, American Chemical Society (ACS)

    Professor Jiang Zheng

  14. Quinoline is more genotoxic than 4-methylquinoline in hiHeps cells and rodent liver

    Article • Mutation Research/Genetic Toxicology and Environmental Mutagenesis, February 2023, Elsevier

    Professor Jiang Zheng

  15. Metabolic Activation of Pesticide Isoprocarb Mediated by CYP3A4 and the Possible Correlation with Its Cytotoxicity

    Article • Journal of Agricultural and Food Chemistry, January 2023, American Chemical Society (ACS)

    Professor Jiang Zheng

  16. Evaluating and predicting the correlations of hepatic concentration and pyrrole-protein adduction with hepatotoxicity induced by retrorsine based on pharmacokinetic/pharmacodynamic model

    Article • Toxicology Letters, January 2023, Elsevier

    Professor Jiang Zheng

  17. Configurational Alteration Results in Change in Hepatotoxicity of Asarone

    Article • Journal of Agricultural and Food Chemistry, December 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  18. 2,3,5,4′-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, a mechanism-based inactivator of CYP2C19 and CYP3A4, potentiates hepatic protein adduction and hepatotoxicity induced by emodin in vivo

    Article • Chemico-Biological Interactions, December 2022, Elsevier

    Professor Jiang Zheng

  19. Diverse sesquiterpenoids from Litsea lancilimba Merr. with potential neuroprotective effects against H2O2-induced SH-SY5Y cell injury

    Article • Chinese Journal of Natural Medicines, September 2022, Elsevier

    Professor Jiang Zheng

  20. Hepatic RNA adduction derived from metabolic activation of retrorsine in vitro and in vivo

    Article • Chemico-Biological Interactions, September 2022, Elsevier

    Professor Jiang Zheng

  21. Evidence for Metabolic Activation of Omeprazole In Vitro and In Vivo

    Article • Chemical Research in Toxicology, August 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  22. Asparagine and Glutamine Residues Participate in Protein Covalent Binding by Epoxide Metabolite of 8-Epidiosbulbin E Acetate In Vitro and In Vivo

    Article • Chemical Research in Toxicology, July 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  23. Evidence for adduction of biologic amines with reactive metabolite of 8-epidiosbulbin E acetate in vitro and in vivo

    Article • Toxicology Letters, July 2022, Elsevier

    Professor Jiang Zheng

  24. Diosbulbin B: An important component responsible for hepatotoxicity and protein covalent binding induced by Dioscorea bulbifera L.

    Article • Phytomedicine, July 2022, Elsevier

    Professor Jiang Zheng

  25. Development of a mechanism-based biomarker for Dioscorea bulbifera L. exposure and hepatotoxicity in rats

    Article • Phytomedicine, July 2022, Elsevier

    Professor Jiang Zheng

  26. Metabolic Activation of Gemfibrozil Mediated by Cytochrome P450 Enzymes and Sulfotransferases

    Article • Chemical Research in Toxicology, June 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  27. Phytochemistry, synthesis, analytical methods, pharmacological activity, and pharmacokinetics of loganin: A comprehensive review

    Article • Phytotherapy Research, May 2022, Wiley

    Professor Jiang Zheng

  28. In Vitro and In Vivo Metabolic Activation and Hepatotoxicity of Environmental Pollutant 2,6-Dimethylphenol

    Article • Chemical Research in Toxicology, May 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  29. Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity

    Article • Chemical Research in Toxicology, May 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  30. DNA damage by reactive oxygen species resulting from metabolic activation of 8-epidiosbulbin E acetate in vitro and in vivo

    Article • Toxicology and Applied Pharmacology, May 2022, Elsevier

    Professor Jiang Zheng

  31. Metabolic activation of 3-aminodibenzofuran mediated by P450 enzymes and sulfotransferases

    Article • Toxicology Letters, May 2022, Elsevier

    Professor Jiang Zheng

  32. Metabolic Activation of Militarine In Vitro and In Vivo

    Article • Chemical Research in Toxicology, April 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  33. Metabolic Activation and Cytotoxicity of Propafenone Mediated by CYP2D6

    Article • Chemical Research in Toxicology, April 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  34. Anastrozole and related glucuronic acid conjugate are electrophilic species

    Article • Xenobiotica, April 2022, Taylor & Francis

    Professor Jiang Zheng

  35. 2-Naphthalenemethanol participates in metabolic activation of 2-methylnaphthalene

    Article • Xenobiotica, April 2022, Taylor & Francis

    Professor Jiang Zheng

  36. Small Molecule Accurate Recognition Technology accelerated isolation of structurally diverse sesquiterpenes from Litsea lancilimba Merr.

    Article • Fitoterapia, April 2022, Elsevier

    Professor Jiang Zheng

  37. A Metabolic Activation-Based Chemoproteomic Platform to Profile Adducted Proteins Derived from Furan-Containing Compounds

    Article • ACS Chemical Biology, March 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  38. Metabolic Activation and Cytotoxicity of Fungicide Carbendazim Mediated by CYP1A2

    Article • Journal of Agricultural and Food Chemistry, March 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  39. Response to the comments raised by Fernando Tricta

    Article • Xenobiotica, March 2022, Taylor & Francis

    Professor Jiang Zheng

  40. Metabolic Activation of Perampanel Mediated by CYP1A2

    Article • Chemical Research in Toxicology, February 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  41. Unique Oxidative Metabolism of Bufalin Generates Two Reactive Metabolites That Strongly Inactivate Human Cytochrome P450 3A

    Article • Journal of Medicinal Chemistry, January 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  42. Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds

    Article • Drug Metabolism and Disposition, January 2022, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  43. Cysteine-Based Protein Covalent Binding and Hepatotoxicity Induced by Emodin

    Article • Chemical Research in Toxicology, January 2022, American Chemical Society (ACS)

    Professor Jiang Zheng

  44. RNA adduction derived from electrophilic species in vitro and in vivo

    Article • Chemico-Biological Interactions, January 2022, Elsevier

    Professor Jiang Zheng

  45. Amino Acid and Biogenic Amine Adductions Derived from Reactive Metabolites

    Article • Current Drug Metabolism, December 2021, Bentham Science Publishers

    Professor Jiang Zheng

  46. Toxicokinetic and bioavailability studies on retrorsine in mice, and ketoconazole‐induced alteration in toxicokinetic properties

    Article • Biomedical Chromatography, November 2021, Wiley

    Professor Jiang Zheng

  47. Glutathione conjugation and protein modification resulting from metabolic activation of venlafaxine in vitro and in vivo

    Article • Xenobiotica, November 2021, Taylor & Francis

    Professor Jiang Zheng

  48. Metabolic activation of zolmitriptan mediated by CYP2D6

    Article • Xenobiotica, November 2021, Taylor & Francis

    Professor Jiang Zheng

  49. Metabolic activation of aegeline mediated by CYP2C19

    Article • Xenobiotica, November 2021, Taylor & Francis

    Professor Jiang Zheng

  50. Metabolic activation of deferiprone mediated by CYP2A6

    Article • Xenobiotica, October 2021, Taylor & Francis

    Professor Jiang Zheng

  51. Oxypeucedanin is a Mechanism-based Inactivator of CYP2B6 and CYP2D6

    Article • Current Drug Metabolism, September 2021, Bentham Science Publishers

    Professor Jiang Zheng

  52. Metabolic Activation of Atomoxetine Mediated by Cytochrome P450 2D6

    Article • Chemical Research in Toxicology, August 2021, American Chemical Society (ACS)

    Professor Jiang Zheng

  53. Icotinib Induces Mechanism-Based Inactivation of Recombinant Human CYP3A4/5 Possibly via Heme Destruction by Ketene Intermediate

    Article • Drug Metabolism and Disposition, July 2021, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  54. Mechanistic study of bergamottin-induced inactivation of CYP2C9

    Article • Food and Chemical Toxicology, July 2021, Elsevier

    Professor Jiang Zheng

  55. Metabolic Activation and Cytotoxicity of Labetalol Hydrochloride Mediated by Sulfotransferases

    Article • Chemical Research in Toxicology, April 2021, American Chemical Society (ACS)

    Professor Jiang Zheng

  56. Reversible and Irreversible Inhibition of Cytochrome P450 Enzymes by Methylophiopogonanone A

    Article • Drug Metabolism and Disposition, April 2021, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  57. In Vitro and In Vivo Evidence for RNA Adduction Resulting from Metabolic Activation of Methyleugenol

    Article • Journal of Agricultural and Food Chemistry, December 2020, American Chemical Society (ACS)

    Professor Jiang Zheng

  58. An LC-MS/MS- and hURAT1 cell-based approach for screening of uricosuric agents

    Article • Journal of Chromatography B, November 2020, Elsevier

    Professor Jiang Zheng

  59. Antibody-based detection of lysine modification of hepatic protein in mice treated with retrorsine

    Article • Journal of Environmental Science and Health Part C, October 2020, Taylor & Francis

    Professor Jiang Zheng

  60. Identification, synthesis and structural confirmation of process-related impurities in proparacaine hydrochloride

    Article • Journal of Pharmaceutical and Biomedical Analysis, October 2020, Elsevier

    Professor Jiang Zheng

  61. Glutathione Conjugation and Protein Adduction by Environmental Pollutant 2,4-Dichlorophenol In Vitro and In Vivo

    Article • Chemical Research in Toxicology, August 2020, American Chemical Society (ACS)

    Professor Jiang Zheng

  62. Dioscorea bulbifera L.-induced hepatotoxicity and involvement of metabolic activation of furanoterpenoids

    Article • Drug Metabolism Reviews, August 2020, Taylor & Francis

    Professor Jiang Zheng

  63. Metabolic Activation of Pirfenidone Mediated by Cytochrome P450s and Sulfotransferases

    Article • Journal of Medicinal Chemistry, July 2020, American Chemical Society (ACS)

    Professor Jiang Zheng

  64. Evidence for Polyamine, Biogenic Amine, and Amino Acid Adduction Resulting from Metabolic Activation of Diosbulbin B

    Article • Chemical Research in Toxicology, June 2020, American Chemical Society (ACS)

    Professor Jiang Zheng

  65. Reply to Letter to Editor from Veeravalli and Dash on “Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4: Revisiting the Significance of the Epoxide Intermediate and Glutathione Trapping”

    Article • Chemical Research in Toxicology, May 2020, American Chemical Society (ACS)

    Professor Jiang Zheng

  66. Mechanism-based inactivation of cytochrome P450 2D6 by Notopterol

    Article • Chemico-Biological Interactions, May 2020, Elsevier

    Professor Jiang Zheng

  67. Immunochemical Detection of Protein Modification Derived from Metabolic Activation of 8-Epidiosbulbin E Acetate

    Article • Chemical Research in Toxicology, April 2020, American Chemical Society (ACS)

    Professor Jiang Zheng

  68. Overcoming Taxol-resistance in A549 cells: A comprehensive strategy of targeting P-gp transporter, AKT/ERK pathways, and cytochrome P450 enzyme CYP1B1 by 4-hydroxyemodin

    Article • Biochemical Pharmacology, January 2020, Elsevier

    Professor Jiang Zheng

  69. Synthesis, bioconversion, pharmacokinetic and pharmacodynamic evaluation of N-isopropyl-oxy-carbonyloxymethyl prodrugs of CZh-226, a potent and selective PAK4 inhibitor

    Article • European Journal of Medicinal Chemistry, January 2020, Elsevier

    Professor Jiang Zheng

  70. Piperine Is a Mechanism-Based Inactivator of CYP3A

    Article • Drug Metabolism and Disposition, November 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  71. Metabolic Activation of Tofacitinib Mediated by Myeloperoxidase in Vitro

    Article • Chemical Research in Toxicology, November 2019, American Chemical Society (ACS)

    Professor Jiang Zheng

  72. Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice

    Article • Drug Metabolism and Disposition, September 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  73. In vitro and in vivo studies of the metabolic activation of chelidonine

    Article • Chemico-Biological Interactions, August 2019, Elsevier

    Professor Jiang Zheng

  74. Studies on hepatotoxicity and toxicokinetics of colchicine

    Article • Journal of Biochemical and Molecular Toxicology, July 2019, Wiley

    Professor Jiang Zheng

  75. Nitidine Chloride–Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism

    Article • Drug Metabolism and Disposition, May 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  76. Identification of Quinone Methide Intermediate Resulting from Metabolic Activation of Icaritin in Vitro and in Vivo

    Article • Chemical Research in Toxicology, April 2019, American Chemical Society (ACS)

    Professor Jiang Zheng

  77. Sex difference in monocrotaline-induced developmental toxicity and fetal hepatotoxicity in rats

    Article • Toxicology, April 2019, Elsevier

    Professor Jiang Zheng

  78. Prenatal exposure to pyrrolizidine alkaloids induced hepatotoxicity and pulmonary injury in fetal rats

    Article • Reproductive Toxicology, April 2019, Elsevier

    Professor Jiang Zheng

  79. Metabolism‐based herb–drug interaction ofCorydalis Bungeanae Herbawith berberinein vitroandin vivoin rats

    Article • Biomedical Chromatography, March 2019, Wiley

    Professor Jiang Zheng

  80. Chemical Reactivity of Aloe-Emodin and Its Hydroxylation Metabolites to Thiols

    Article • Chemical Research in Toxicology, January 2019, American Chemical Society (ACS)

    Professor Jiang Zheng

  81. In Vitro DNA Adduction Resulting from Metabolic Activation of Diosbulbin B and 8-Epidiosbulbin E Acetate

    Article • Chemical Research in Toxicology, December 2018, American Chemical Society (ACS)

    Professor Jiang Zheng

  82. Characterization of glutathione conjugates derived from reactive metabolites of seven silymarin isomers

    Article • Xenobiotica, November 2018, Taylor & Francis

    Professor Jiang Zheng

  83. A Difference in Internal Exposure Makes Newly Weaned Mice More Susceptible to the Hepatotoxicity of Retrorsine Than Adult Mice

    Article • Chemical Research in Toxicology, November 2018, American Chemical Society (ACS)

    Professor Jiang Zheng

  84. Cytochrome P450 mediated metabolic activation of chrysophanol

    Article • Chemico-Biological Interactions, June 2018, Elsevier

    Professor Jiang Zheng

  85. Nitidine Chloride Is a Mechanism-Based Inactivator of CYP2D6

    Article • Drug Metabolism and Disposition, May 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  86. In Vitro and in Vivo Studies of the Electrophilicity of Physcion and its Oxidative Metabolites

    Article • Chemical Research in Toxicology, April 2018, American Chemical Society (ACS)

    Professor Jiang Zheng

  87. Development of Polyclonal Antibodies for Detection of Diosbulbin B-Derived cis-Enedial Protein Adducts

    Article • Chemical Research in Toxicology, March 2018, American Chemical Society (ACS)

    Professor Jiang Zheng

  88. Urinary Methyleugenol-deoxyadenosine Adduct as a Potential Biomarker of Methyleugenol Exposure in Rats

    Article • Journal of Agricultural and Food Chemistry, January 2018, American Chemical Society (ACS)

    Professor Jiang Zheng

  89. Maternal-Fetal Disposition and Metabolism of Retrorsine in Pregnant Rats

    Article • Drug Metabolism and Disposition, January 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  90. Identification of Ketene-Reactive Intermediate of Erlotinib Possibly Responsible for Inactivation of P450 Enzymes

    Article • Drug Metabolism and Disposition, January 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  91. Metabolic Epoxidation Is a Critical Step for the Development of Benzbromarone-Induced Hepatotoxicity

    Article • Drug Metabolism and Disposition, October 2017, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  92. Metabolite profile analysis and pharmacokinetic study of emodin, baicalin and geniposide in rats

    Article • Xenobiotica, October 2017, Taylor & Francis

    Professor Jiang Zheng

  93. Chemical Identity of Interaction of Protein with Reactive Metabolite of Diosbulbin B In Vitro and In Vivo

    Article • Toxins, August 2017, MDPI AG

    Professor Jiang Zheng

  94. Pharmacokinetic comparison of two phenolic acids after oral administration of Typhae pollen to normal rats and rats with acute cold blood stasis

    Article • Biomedical Chromatography, July 2017, Wiley

    Professor Jiang Zheng

  95. Sensitive bromine-based screening of potential toxic furanoids in Dioscorea bulbifera L.

    Article • Journal of Chromatography B, July 2017, Elsevier

    Professor Jiang Zheng

  96. Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids

    Article • Journal of Environmental Science and Health Part C, May 2017, Taylor & Francis

    Professor Jiang Zheng

  97. Chemical Interaction of Protein Cysteine Residues with Reactive Metabolites of Methyleugenol

    Article • Chemical Research in Toxicology, February 2017, American Chemical Society (ACS)

    Professor Jiang Zheng

  98. Comparative Study of Hepatotoxicity of Pyrrolizidine Alkaloids Retrorsine and Monocrotaline

    Article • Chemical Research in Toxicology, January 2017, American Chemical Society (ACS)

    Professor Jiang Zheng

  99. Lysine- and cysteine-based protein adductions derived from toxic metabolites of 8-epidiosbulbin E acetate

    Article • Toxicology Letters, December 2016, Elsevier

    Professor Jiang Zheng

  100. In vitro and in vivo metabolic activation of berbamine to quinone methide intermediate

    Article • Journal of Biochemical and Molecular Toxicology, November 2016, Wiley

    Professor Jiang Zheng

  101. Cytochrome P450 Mediated Bioactivation of Saracatinib

    Article • Chemical Research in Toxicology, November 2016, American Chemical Society (ACS)

    Professor Jiang Zheng

  102. Simultaneous assessment of endogenous thiol compounds by LC–MS/MS

    Article • Journal of Chromatography B, September 2016, Elsevier

    Professor Jiang Zheng

  103. Identification of glutathione and related cysteine conjugates derived from reactive metabolites of methyleugenol in rats

    Article • Chemico-Biological Interactions, June 2016, Elsevier

    Professor Jiang Zheng

  104. Oxidative bioactivation of nitrofurantoin in rat liver microsomes

    Article • Xenobiotica, April 2016, Taylor & Francis

    Professor Jiang Zheng

  105. Detection of protein adduction derived from dauricine by alkaline permethylation

    Article • Analytical and Bioanalytical Chemistry, April 2016, Springer Science + Business Media

    Professor Jiang Zheng

  106. Design, synthesis and biological evaluation of N,N-3-phenyl-3-benzylaminopropanamide derivatives as novel cholesteryl ester transfer protein inhibitor

    Article • Bioorganic & Medicinal Chemistry, April 2016, Elsevier

    Professor Jiang Zheng

  107. Role of Metabolic Activation in 8-Epidiosbulbin E Acetate-Induced Liver Injury: Mechanism of Action of the Hepatotoxic Furanoid

    Article • Chemical Research in Toxicology, February 2016, American Chemical Society (ACS)

    Professor Jiang Zheng

  108. 9-Glutathionyl-6,7-dihydro-1-hydroxymethyl-5H-pyrrolizine Is the Major Pyrrolic Glutathione Conjugate of Retronecine-Type Pyrrolizidine Alkaloids in Liver Microsomes and in Rats

    Article • Chemical Research in Toxicology, January 2016, American Chemical Society (ACS)

    Professor Jiang Zheng

  109. Identification of Epoxide-Derived Metabolite(s) of Benzbromarone

    Article • Drug Metabolism and Disposition, January 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  110. Characterization of glutathione conjugates derived from reactive metabolites of bakuchiol

    Article • Chemico-Biological Interactions, January 2016, Elsevier

    Professor Jiang Zheng

  111. Homoharringtonine binds to and increases myosin-9 in myeloid leukaemia

    Article • British Journal of Pharmacology, December 2015, Wiley

    Professor Jiang Zheng

  112. Detection of cysteine- and lysine-based protein adductions by reactive metabolites of 2,5-dimethylfuran

    Article • Analytica Chimica Acta, October 2015, Elsevier

    Professor Jiang Zheng

  113. Psoralen, a mechanism-based inactivator of CYP2B6

    Article • Chemico-Biological Interactions, October 2015, Elsevier

    Professor Jiang Zheng

  114. Blood Pyrrole-Protein Adducts—A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans

    Article • Journal of Environmental Science and Health Part C, September 2015, Taylor & Francis

    Professor Jiang Zheng

  115. CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine

    Article • Archives of Toxicology, August 2015, Springer Science + Business Media

    Professor Jiang Zheng

  116. Mechanism-based inactivation of cytochrome P450 2B6 by isopsoralen

    Article • Xenobiotica, August 2015, Taylor & Francis

    Professor Jiang Zheng

  117. In Vitro and In Vivo Characterization of Reactive Intermediates of Corynoline

    Article • Drug Metabolism and Disposition, August 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  118. Comparative studies of pharmacokinetics and anticoagulatory effect in rats after oral administration of Frankincense and its processed products

    Article • Journal of Ethnopharmacology, August 2015, Elsevier

    Professor Jiang Zheng

  119. Mechanism-based inactivation of CYP2C9 by linderane

    Article • Xenobiotica, June 2015, Taylor & Francis

    Professor Jiang Zheng

  120. Mass spectrometry based detection of glutathione with sensitivity for single-cell analysis

    Article • Rapid Communications in Mass Spectrometry, April 2015, Wiley

    Professor Jiang Zheng

  121. Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic

    Article • Archives of Toxicology, April 2015, Springer Science + Business Media

    Professor Jiang Zheng

  122. Mechanism-based inactivation of cytochrome P450 2B6 by isoimperatorin

    Article • Chemico-Biological Interactions, January 2015, Elsevier

    Professor Jiang Zheng

  123. N-Acetyl Lysine/Glutathione-Derived Pyrroles as Potential Ex Vivo Biomarkers of Bioactivated Furan-Containing Compounds

    Article • Chemical Research in Toxicology, December 2014, American Chemical Society (ACS)

    Professor Jiang Zheng

  124. Imperatorin Is a Mechanism-Based Inactivator of CYP2B6

    Article • Drug Metabolism and Disposition, November 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng

  125. Selective and Sensitive Platform for Function-Based Screening of Potentially Harmful Furans

    Article • Analytical Chemistry, October 2014, American Chemical Society (ACS)

    Professor Jiang Zheng

  126. Cytochrome P450–Mediated Metabolic Activation of Diosbulbin B

    Article • Drug Metabolism and Disposition, July 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Jiang Zheng