All Stories

  1. Synergistic antitumor efficacy of antibacterial helvolic acid from Cordyceps taii and cyclophosphamide in a tumor mouse model

    Article • Experimental Biology and Medicine, September 2016, SAGE Publications

    Professor Jian-Jiang Zhong

  2. Improvement of ganoderic acid production by fermentation of Ganoderma lucidum with cellulase as an elicitor

    Article • Process Biochemistry, October 2014, Elsevier

    Professor Jian-Jiang Zhong

  3. Enhanced production of validamycin A in Streptomyces hygroscopicus 5008 by engineering validamycin biosynthetic gene cluster

    Article • Applied Microbiology and Biotechnology, July 2014, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  4. Induction of ganoderic acid biosynthesis by Mn2+ in static liquid cultivation of Ganoderma lucidum

    Article • Biotechnology and Bioengineering, July 2014, Wiley

    Professor Jian-Jiang Zhong

  5. Triggering Respirofermentative Metabolism in the Crabtree-Negative Yeast Pichia guilliermondii by Disrupting theCAT8Gene

    Article • Applied and Environmental Microbiology, April 2014, ASM Journals

    Professor Jian-Jiang Zhong

  6. Screening of Ganoderma strains with high polysaccharides and ganoderic acid contents and optimization of the fermentation medium by statistical methods

    Article • Bioprocess and Biosystems Engineering, February 2014, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  7. Oxygen limitation improves ganoderic acid biosynthesis in submerged cultivation of Ganoderma lucidum

    Article • Biotechnology and Bioprocess Engineering, September 2013, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  8. Exogenous 1,4‐butyrolactone stimulates A‐factor‐like cascade and validamycin biosynthesis in Streptomyces hygroscopicus 5008

    Article • Biotechnology and Bioengineering, August 2013, Wiley

    Professor Jian-Jiang Zhong

  9. Induced effect of Na+ on ganoderic acid biosynthesis in static liquid culture of Ganoderma lucidum via calcineurin signal transduction

    Article • Biotechnology and Bioengineering, February 2013, Wiley

    Professor Jian-Jiang Zhong

  10. Enhanced recovery of four antitumor ganoderic acids from Ganoderma lucidum mycelia by a novel process of simultaneous extraction and hydrolysis

    Article • Process Biochemistry, February 2013, Elsevier

    Professor Jian-Jiang Zhong

  11. A new ganoderic acid from Ganoderma lucidum mycelia and its stability

    Article • Fitoterapia, January 2013, Elsevier

    Professor Jian-Jiang Zhong

  12. Volatile organic compounds from a Tuber melanosporum fermentation system

    Article • Food Chemistry, December 2012, Elsevier

    Professor Jian-Jiang Zhong

  13. Impacts of calcium signal transduction on the fermentation production of antitumor ganoderic acids by medicinal mushroom Ganoderma lucidum

    Article • Biotechnology Advances, November 2012, Elsevier

    Professor Jian-Jiang Zhong

  14. Enhancement of Ganoderic Acid Accumulation by Overexpression of an N-Terminally Truncated 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene in the Basidiomycete Ganoderma lucidum

    Article • Applied and Environmental Microbiology, August 2012, ASM Journals

    Professor Jian-Jiang Zhong

  15. Enhancement of validamycin A production by addition of ethanol in fermentation of Streptomyces hygroscopicus 5008

    Article • Bioresource Technology, June 2012, Elsevier

    Professor Jian-Jiang Zhong

  16. Recovery of ganoderic acids from Ganoderma lucidum mycelia by macroporous adsorption resins

    Article • Biotechnology and Bioprocess Engineering, April 2012, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  17. Isolation and characterization of a novel Ganoderma lucidum gene that differentially expressed between shaking culture and liquid static culture

    Article • Genes & Genomics, December 2011, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  18. Enhanced recovery of antitumor ganoderic acid T from Ganoderma lucidum mycelia by novel chemical conversion strategy

    Article • Biotechnology and Bioengineering, November 2011, Wiley

    Professor Jian-Jiang Zhong

  19. Enhanced production of ansamitocin P-3 by addition of Mg2+ in fermentation of Actinosynnema pretiosum

    Article • Bioresource Technology, November 2011, Elsevier

    Professor Jian-Jiang Zhong

  20. Enhanced production of ganoderic acids in static liquid culture of Ganoderma lucidum under nitrogen-limiting conditions

    Article • Bioresource Technology, September 2011, Elsevier

    Professor Jian-Jiang Zhong

  21. Isolation and analysis of differentially expressed genes during asexual sporulation in liquid static culture of Ganoderma lucidum by suppression subtractive hybridization

    Article • Molecular Biology Reports, July 2011, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  22. Effects of Ganoderic acid Me on inhibiting multidrug resistance and inducing apoptosis in multidrug resistant colon cancer cells

    Article • Process Biochemistry, June 2011, Elsevier

    Professor Jian-Jiang Zhong

  23. CO2 biofixation and fatty acid composition of Scenedesmus obliquus and Chlorella pyrenoidosa in response to different CO2 levels

    Article • Bioresource Technology, February 2011, Elsevier

    Professor Jian-Jiang Zhong

  24. In SituBiodiesel Production from Fast-Growing and High Oil ContentChlorella pyrenoidosain Rice Straw Hydrolysate

    Article • Journal of Biomedicine and Biotechnology, January 2011, Hindawi Publishing Corporation

    Professor Jian-Jiang Zhong

  25. Bioreactor Engineering

    Article • January 2011, Elsevier

    Professor Jian-Jiang Zhong

  26. Scale-up study on the fed-batch fermentation of Ganoderma lucidum for the hyperproduction of ganoderic acid and Ganoderma polysaccharides

    Article • Process Biochemistry, January 2011, Elsevier

    Professor Jian-Jiang Zhong

  27. Enhanced production of validamycin A by H2O2-induced reactive oxygen species in fermentation of Streptomyces hygroscopicus 5008

    Article • Bioresource Technology, January 2011, Elsevier

    Professor Jian-Jiang Zhong

  28. Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum

    Article • Bioresource Technology, January 2011, Elsevier

    Professor Jian-Jiang Zhong

  29. Plant Secondary Metabolites

    Article • January 2011, Elsevier

    Professor Jian-Jiang Zhong

  30. Multi-fed batch culture integrated with three-stage light irradiation and multiple additions of copper ions for the hyperproduction of ganoderic acid and Ganoderma polysaccharides by the medicinal mushroom Ganoderma lucidum

    Article • Process Biochemistry, December 2010, Elsevier

    Professor Jian-Jiang Zhong

  31. Separation and determination of four ganoderic acids from dried fermentation mycelia powder of Ganoderma lucidum by capillary zone electrophoresis

    Article • Journal of Pharmaceutical and Biomedical Analysis, December 2010, Elsevier

    Professor Jian-Jiang Zhong

  32. Antimetastatic effect of ganoderic acid T in vitro through inhibition of cancer cell invasion

    Article • Process Biochemistry, August 2010, Elsevier

    Professor Jian-Jiang Zhong

  33. A new ganoderic acid from Ganoderma lucidum mycelia

    Article • Journal of Asian Natural Products Research, August 2010, Taylor & Francis

    Professor Jian-Jiang Zhong

  34. Sorbitol production using recombinant Zymomonas mobilis strain

    Article • Journal of Biotechnology, July 2010, Elsevier

    Professor Jian-Jiang Zhong

  35. Enhanced biosynthetic gene expressions and production of ganoderic acids in static liquid culture of Ganoderma lucidum under phenobarbital induction

    Article • Applied Microbiology and Biotechnology, January 2010, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  36. Effect of oxygen concentration in gas phase on sporulation and individual ganoderic acids accumulation in liquid static culture of Ganoderma lucidum

    Article • Journal of Bioscience and Bioengineering, January 2010, Elsevier

    Professor Jian-Jiang Zhong

  37. H2O2-induced reactive oxygen species regulated gene transcription, enzyme activity and validamycin A biosynthesis by Streptomyces hygroscopicus 5008

    Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

    Professor Jian-Jiang Zhong

  38. Two cytotoxic sesquiterpenes from hairy root cultures of Artemisia annua L. induced apoptosis of highly metastatic lung carcinoma cell line 95-D

    Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

    Professor Jian-Jiang Zhong

  39. Purification and identification of 7-O-ethyl ganoderic acid O from fermented mycelia of Ganoderma lucidum and its conversion to other ganoderic acids

    Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

    Professor Jian-Jiang Zhong

  40. Comparison of individual ganoderic acids production and identification of differentially expressed genes between liquid static culture and shaking culture of Ganoderma lucidum

    Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

    Professor Jian-Jiang Zhong

  41. Fermentation, purification and characterization of a new antiviral ribonuclease produced by Bacillus cereus

    Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

    Professor Jian-Jiang Zhong

  42. Impact of oxygen level in gaseous phase on gene transcription and ganoderic acid biosynthesis in liquid static cultures of Ganoderma lucidum

    Article • Bioprocess and Biosystems Engineering, October 2009, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  43. Fermentation condition outweighed truffle species in affecting volatile organic compounds analyzed by chromatographic fingerprint system

    Article • Analytica Chimica Acta, August 2009, Elsevier

    Professor Jian-Jiang Zhong

  44. Production of individual ganoderic acids and expression of biosynthetic genes in liquid static and shaking cultures of Ganoderma lucidum

    Article • Applied Microbiology and Biotechnology, July 2009, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  45. Effect of fermentation temperature on validamycin A production by Streptomyces hygroscopicus 5008

    Article • Journal of Biotechnology, July 2009, Elsevier

    Professor Jian-Jiang Zhong

  46. Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum

    Article • Bioresource Technology, March 2009, Elsevier

    Professor Jian-Jiang Zhong

  47. Significance of fungal elicitors on the production of ganoderic acid and Ganoderma polysaccharides by the submerged culture of medicinal mushroom Ganoderma lucidum

    Article • Process Biochemistry, December 2008, Elsevier

    Professor Jian-Jiang Zhong

  48. A signal transduction cascade from defense signal response to taxoid biosynthesis by elicitation of a novel synthetic benzothiadiazole in Taxus chinensis

    Article • Journal of Biotechnology, October 2008, Elsevier

    Professor Jian-Jiang Zhong

  49. Chemical biotechnology and engineering: Cell elicitors, artificial nucleases and fluorescent sensors of heterocycles

    Article • Journal of Biotechnology, October 2008, Elsevier

    Professor Jian-Jiang Zhong

  50. Simultaneous determination of four triterpenoids of Ganoderma lucidum by reverse-phase high-performance liquid chromatography-diode array detector

    Article • Journal of Biotechnology, October 2008, Elsevier

    Professor Jian-Jiang Zhong

  51. Fermentation temperature is significant to validamycin a biosynthesis by Streptomyces hygroscopicus 5008

    Article • Journal of Biotechnology, October 2008, Elsevier

    Professor Jian-Jiang Zhong

  52. Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells

    Article • Life Sciences, December 2006, Elsevier

    Professor Jian-Jiang Zhong

  53. Separation of targeted ganoderic acids from Ganoderma lucidum by reversed phase liquid chromatography with ultraviolet and mass spectrometry detections

    Article • Biochemical Engineering Journal, December 2006, Elsevier

    Professor Jian-Jiang Zhong

  54. Novel, Unnatural Benzo-1,2,3-thiadiazole-7-carboxylate Elicitors of Taxoid Biosynthesis

    Article • Journal of Agricultural and Food Chemistry, October 2006, American Chemical Society (ACS)

    Professor Jian-Jiang Zhong

  55. Extraction of 20(S)-Ginsenoside Rg2 from Cultured Panax notoginseng Cells In Vitro Stimulates Human Umbilical Cord Vein Endothelial Cell Proliferation

    Article • American Journal of Therapeutics, May 2006, Wolters Kluwer Health

    Professor Jian-Jiang Zhong

  56. Protection effect of 20(S)-ginsenoside Rg2 extracted from cultured Panax notoginseng cells on hydrogen peroxide-induced cytotoxity of human umbilical cord vein endothelial cells in vitro

    Article • Process Biochemistry, October 2005, Elsevier

    Professor Jian-Jiang Zhong

  57. Enhancement of microbial transglutaminase production by Streptoverticillium mobaraense: application of a two-stage agitation speed control strategy

    Article • Process Biochemistry, February 2005, Elsevier

    Professor Jian-Jiang Zhong

  58. Modeling the kinetics of cell growth and ganoderic acid production in liquid static cultures of the medicinal mushroom Ganoderma lucidum

    Article • Biochemical Engineering Journal, November 2004, Elsevier

    Professor Jian-Jiang Zhong

  59. Novel Fermentation Strategy for Enhancing Glycerol Production by Candida krusei

    Article • Biotechnology Progress, October 2003, Wiley

    Professor Jian-Jiang Zhong

  60. Role of oxygen supply in submerged fermentation of Ganoderma lucidum for production of Ganoderma polysaccharide and ganoderic acid

    Article • Enzyme and Microbial Technology, March 2003, Elsevier

    Professor Jian-Jiang Zhong

  61. Scale‐Up of a Liquid Static Culture Process for Hyperproduction of Ganoderic Acid by the Medicinal Mushroom Ganodermalucidum

    Article • Biotechnology Progress, January 2003, Wiley

    Professor Jian-Jiang Zhong

  62. Significance of inoculation density control in production of polysaccharide and ganoderic acid by submerged culture of Ganoderma lucidum

    Article • Process Biochemistry, July 2002, Elsevier

    Professor Jian-Jiang Zhong

  63. Fed-batch fermentation of Ganoderma lucidum for hyperproduction of polysaccharide and ganoderic acid

    Article • Enzyme and Microbial Technology, July 2002, Elsevier

    Professor Jian-Jiang Zhong

  64. Two-Stage Culture Process for Improved Production of Ganoderic Acid by Liquid Fermentation of Higher Fungus Ganoderma lucidum

    Article • Biotechnology Progress, February 2002, Wiley

    Professor Jian-Jiang Zhong

  65. Submerged fermentation of higher fungus Ganoderma lucidum for production of valuable bioactive metabolites—ganoderic acid and polysaccharide

    Article • Biochemical Engineering Journal, February 2002, Elsevier

    Professor Jian-Jiang Zhong

  66. Effect of initial pH on production of ganoderic acid and polysaccharide by submerged fermentation of Ganoderma lucidum

    Article • Process Biochemistry, February 2002, Elsevier

    Professor Jian-Jiang Zhong

  67. Plant Cell Culture for Production of Paclitaxel and Other Taxanes.

    Article • Journal of Bioscience and Bioengineering, January 2002, Elsevier

    Professor Jian-Jiang Zhong

  68. Biochemical Engineering of the Production of Plant-Specific Secondary Metabolites by Cell Suspension Cultures

    Article • January 2001, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  69. Effects of initial phosphate concentration on physiological aspects of suspension cultures of rice cells: A kinetic study

    Article • Journal of Fermentation and Bioengineering, January 1997, Elsevier

    Professor Jian-Jiang Zhong

  70. Short communication: Production of l-glutamate oxidase by Streptomyces sp. N1 in submerged fermentation

    Article • World Journal of Microbiology and Biotechnology, November 1996, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  71. Enhancement of L-glutamate oxidase production in liquid fermentation of Streptomyces sp. by calcium addition

    Article • Biotechnology Techniques, June 1996, Springer Science + Business Media

    Professor Jian-Jiang Zhong

  72. Effects of temperature on cell growth and anthocyanin production in suspension cultures of Perilla frutescens

    Article • Journal of Fermentation and Bioengineering, January 1993, Elsevier

    Professor Jian-Jiang Zhong