All Stories

  1. Recognition of a Conserved Minimal Catalaphile Explains Catalyst Generality in Enantioselective Nitroalkene Reductions

    Article • ACS Catalysis, June 2026, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  2. Selective RyR2 inhibition reduces arrhythmia susceptibility in human cardiac slices

    Article • The Journal of Physiology, January 2026, Wiley

    Professor Jeffrey N. Johnston

  3. Performance-enhancing asymmetric catalysis unlocks tuning without rebuilding

    Article • Chem Catalysis, November 2025, Elsevier

    Professor Jeffrey N. Johnston

  4. Introduction of a Single Carboxylic Acid Converts the Cyclic Oligomeric Depsipeptide ent-Verticilide from an RyR2 Inhibitor to RyR2 Activator

    Article • Molecular Pharmacology, October 2025, Elsevier

    Professor Jeffrey N. Johnston

  5. Performance-Enhancing Asymmetric Catalysis Driven by Achiral Counterion Design

    Article • Journal of the American Chemical Society, May 2025, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  6. End-to-End Backbone Cyclization Enhances Passive Permeability of bRo5 Oligomeric Depsipeptides with Nonlinear Size Dependence

    Article • ACS Medicinal Chemistry Letters, March 2025, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  7. Elucidating Fluorine Steering Effects in Diels‐Alder Reactions Interfaced with Charge‐Enhanced Reactivity

    Article • European Journal of Organic Chemistry, January 2025, Wiley

    Professor Jeffrey N. Johnston

  8. Backbone-Determined Antiarrhythmic Structure–Activity Relationships for a Mirror Image, Oligomeric Depsipeptide Natural Product

    Article • Journal of Medicinal Chemistry, July 2024, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  9. ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2−/− Mice

    Article • Molecular Pharmacology, March 2024, Elsevier

    Professor Jeffrey N. Johnston

  10. Generality-Driven Catalyst Development: A Universal Catalyst for Enantioselective Nitroalkene Reduction

    Article • Journal of the American Chemical Society, January 2024, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  11. The backbone constitution drives passive permeability independent of side chains in depsipeptide and peptide macrocycles inspired by ent-verticilide

    Article • Chemical Science, January 2024, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  12. ent-Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice

    Article • July 2023, Cold Spring Harbor Laboratory Press

    Professor Jeffrey N. Johnston

  13. The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency

    Article • Journal of Molecular and Cellular Cardiology, July 2023, Elsevier

    Professor Jeffrey N. Johnston

  14. RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

    Article • June 2023, Cold Spring Harbor Laboratory Press

    Professor Jeffrey N. Johnston

  15. In Vivo Pharmacokinetic and Pharmacodynamic Properties of the Antiarrhythmic Molecule ent-Verticilide

    Article • Journal of Pharmacology and Experimental Therapeutics, June 2023, Elsevier

    Professor Jeffrey N. Johnston

  16. Secondary Orbital Effect Involving Fluorine is Responsible for Substrate‐Controlled Diastereodivergence in the Catalyzed syn‐aza‐Henry Reaction of α‐Fluoronitroalkanes

    Article • Chemistry - A European Journal, March 2023, Wiley

    Professor Jeffrey N. Johnston

  17. Enantioselective Synthesis of cis- and trans-Cycloheptyl β-Fluoro Amines by Sequential aza-Henry Addition/Ring-Closing Metathesis

    Article • Organic Letters, February 2023, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  18. Structure–Activity Relationships for the N-Me- Versus N-H-Amide Modification to Macrocyclic ent-Verticilide Antiarrhythmics

    Article • ACS Medicinal Chemistry Letters, October 2022, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  19. Preparation of N-Aryl Amides by Epimerization-Free Umpolung Amide Synthesis

    Article • Journal of the American Chemical Society, September 2022, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  20. Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2–Deficient Hearts

    Article • Circulation, May 2022, Wolters Kluwer Health

    Professor Jeffrey N. Johnston

  21. Resolving Bromonitromethane Sourcing by Synthesis: Preparation at the Decagram Scale

    Article • The Journal of Organic Chemistry, April 2022, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  22. Enantioselective iodolactonization to prepare ε-lactone rings using hypervalent iodine

    Article • Chemical Science, January 2022, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  23. Fluorine-induced diastereodivergence discovered in an equally rare enantioselective syn-aza-Henry reaction

    Article • Chemical Science, January 2022, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  24. Ring Size as an Independent Variable in Cyclooligomeric Depsipeptide Antiarrhythmic Activity

    Article • ACS Medicinal Chemistry Letters, November 2021, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  25. DFT-Based Stereochemical Rationales for the Bifunctional Brønsted Acid/Base-Catalyzed Diastereodivergent and Enantioselective aza-Henry Reactions of α-Nitro Esters

    Article • The Journal of Organic Chemistry, October 2021, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  26. The Formation of Impossible Rings in Macrocyclooligomerizations for Cyclodepsipeptide Synthesis: The 18-from-12 Paradox

    Article • The Journal of Organic Chemistry, June 2021, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  27. Correction to “Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides”

    Article • Journal of the American Chemical Society, April 2021, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  28. RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT

    Article • Circulation Research, February 2021, Wolters Kluwer Health

    Professor Jeffrey N. Johnston

  29. Substituted Imidazoline Synthesis: A Diastereo- and Enantioselective aza-Henry Route to a Human Proteasome Modulator

    Article • Organic Letters, October 2020, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  30. Direct Observation and Analysis of the Halo-Amino-Nitro Alkane Functional Group

    Article • Chem, May 2019, Elsevier

    Professor Jeffrey N. Johnston

  31. Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic

    Article • Proceedings of the National Academy of Sciences, February 2019, Proceedings of the National Academy of Sciences

    Professor Jeffrey N. Johnston

  32. The inverted ketene synthon: a double umpolung approach to enantioselective β2,3-amino amide synthesis

    Article • Chemical Science, January 2019, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  33. Catalytic, Enantioselective Synthesis of Cyclic Carbamates from Dialkyl Amines by CO2-Capture: Discovery, Development, and Mechanism

    Article • Journal of the American Chemical Society, December 2018, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  34. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

    Article • ACS Central Science, December 2018, American Chemical Society (ACS)

    Wei Shi, Professor Jeffrey N. Johnston

  35. Enantioselective Organocatalytic Amine-Isocyanate Capture-Cyclization: Regioselective Alkene Iodoamination for the Synthesis of Chiral Cyclic Ureas

    Article • ACS Catalysis, November 2018, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  36. Canvass: A Crowd-Sourced, Natural Product Screening Library for Exploring Biological Space

    Article • October 2018, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  37. Continuous Platform To Generate Nitroalkanes On-Demand (in Situ) Using Peracetic Acid-Mediated Oxidation in a PFA Pipes-in-Series Reactor

    Article • Organic Process Research & Development, July 2018, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  38. Preparation of Benzyl(( R )‐2‐(4‐(benzyloxy)phenyl)‐2‐(( tert ‐Butoxycarbonyl)Amino)Acetyl)‐D‐Phenylalaninate Using Umpolung Amide Synthesis

    Article • June 2018, Wiley

    Professor Jeffrey N. Johnston

  39. Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides

    Article • Journal of the American Chemical Society, March 2018, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  40. Cluster Preface: Alkene Halofunctionalization

    Article • Synlett, February 2018, Thieme Publishing Group

    Professor Jeffrey N. Johnston

  41. Biomimetic Desymmetrization of a Carboxylic Acid

    Article • Journal of the American Chemical Society, February 2018, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  42. Diastereo- and enantioselective additions of α-nitro esters to imines for anti-α,β-diamino acid synthesis with α-alkyl-substitution

    Article • Chemical Science, January 2018, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  43. MDM2 Antagonists Counteract Drug-Induced DNA Damage

    Article • EBioMedicine, October 2017, Elsevier

    Professor Jeffrey N. Johnston

  44. 1,3,4-Oxadiazole and Heteroaromatic-Fused 1,2,4-Triazole Synthesis­ Using Diverted Umpolung Amide Synthesis

    Article • Synthesis, August 2017, Thieme Publishing Group

    Professor Jeffrey N. Johnston

  45. A convergent synthesis of 1,3,4-oxadiazoles from acyl hydrazides under semiaqueous conditions

    Article • Chemical Science, January 2017, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  46. Rapid synthesis of cyclic oligomeric depsipeptides with positional, stereochemical, and macrocycle size distribution control

    Article • Proceedings of the National Academy of Sciences, December 2016, Proceedings of the National Academy of Sciences

    Professor Jeffrey N. Johnston

  47. Enantioselective Synthesis of β-Fluoro Amines via β-Amino α-Fluoro Nitroalkanes and a Traceless Activating Group Strategy

    Article • Journal of the American Chemical Society, October 2016, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  48. On-Demand Complex Peptide Synthesis: An Aspirational (and Elusive?) Goal for Peptide Synthesis

    Article • Journal of the American Chemical Society, October 2016, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  49. Development of an Intermittent-Flow Enantioselective Aza-Henry Reaction Using an Arylnitromethane and Homogeneous Brønsted Acid–Base Catalyst with Recycle

    Article • Organic Process Research & Development, February 2016, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  50. A one-pot amidation of primary nitroalkanes

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  51. Enantioselective Synthesis of α-Bromonitroalkanes for Umpolung Amide Synthesis: Preparation of tert-Butyl ((1R)-1-(4-(benzyloxy)phenyl)-2-bromo-2-nitroethyl)carbamate

    Article • Organic Syntheses, January 2016, Organic Syntheses

    Professor Jeffrey N. Johnston

  52. Enantioselective Addition of Bromonitromethane to Aliphatic N-Boc Aldimines Using a Homogeneous Bifunctional Chiral Organocatalyst

    Article • ACS Catalysis, October 2015, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  53. ChemInform Abstract: Oxidative Inter-/Intermolecular Alkene Diamination of Hydroxy Styrenes with Electron-Rich Amines.

    Article • ChemInform, September 2015, Wiley

    Professor Jeffrey N. Johnston

  54. A Unified Approach to the Four Azaindoline Families by Inter-/Intramolecular Annulative Diamination of Vinylpyridines

    Article • Organic Letters, July 2015, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  55. Abstract B12: Synergistic anticancer activity of Aurora A kinase and MDM2 antagonists in melanoma

    Article • Cancer Research, July 2015, American Association for Cancer Research (AACR)

    Professor Jeffrey N. Johnston

  56. ChemInform Abstract: Enantioselective Synthesis of D-α-Amino Amides from Aliphatic Aldehydes.

    Article • ChemInform, July 2015, Wiley

    Professor Jeffrey N. Johnston

  57. Enantioselective Small Molecule Synthesis by Carbon Dioxide Fixation using a Dual Brønsted Acid/Base Organocatalyst

    Article • Journal of the American Chemical Society, June 2015, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  58. Oxidative Inter-/Intermolecular Alkene Diamination of Hydroxy Styrenes with Electron-Rich Amines

    Article • Organic Letters, May 2015, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  59. ChemInform Abstract: Broensted Acid Catalyzed Phosphoramidic Acid Additions to Alkenes: Diastereo- and Enantioselective Halogenative Cyclizations for the synthesis of C- and P-Chiral Phosphoramidates.

    Article • ChemInform, April 2015, Wiley

    Professor Jeffrey N. Johnston

  60. ChemInform Abstract: Umpolung Amide Synthesis Using Substoichiometric N-Iodosuccinimide (NIS) and Oxygen as a Terminal Oxidant.

    Article • ChemInform, February 2015, Wiley

    Professor Jeffrey N. Johnston

  61. Adaptation of a Small-Molecule Hydrogen-Bond Donor Catalyst to an Enantioselective Hetero-Diels–Alder Reaction Hypothesized for Brevianamide Biosynthesis

    Article • Organic Letters, January 2015, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  62. ChemInform Abstract: Organocatalytic, Diastereo‐ and Enantioselective Synthesis of Nonsymmetric cis‐Stilbene Diamines: A Platform for the Preparation of Single‐Enantiomer cis‐Imidazolines for Protein—Protein Inhibition.

    Article • ChemInform, January 2015, Wiley

    Professor Jeffrey N. Johnston

  63. Enantioselective synthesis of d-α-amino amides from aliphatic aldehydes

    Article • Chemical Science, January 2015, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  64. Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells

    Article • Cancer Research, January 2015, American Association for Cancer Research (AACR)

    Professor Jeffrey N. Johnston

  65. ChemInform Abstract: Alkene Diamination Using Electron-Rich Amines: Hypervalent Iodine-Promoted Inter-/Intramolecular C-N Bond Formation.

    Article • ChemInform, December 2014, Wiley

    Professor Jeffrey N. Johnston

  66. ChemInform Abstract: Silyl Imine Electrophiles in Enantioselective Catalysis: A Rosetta Stone for Peptide Homologation, Enabling Diverse N-Protected Aryl Glycines from Aldehydes in Three Steps.

    Article • ChemInform, November 2014, Wiley

    Professor Jeffrey N. Johnston

  67. Brønsted Acid Catalyzed Phosphoramidic Acid Additions to Alkenes: Diastereo- and Enantioselective Halogenative Cyclizations for the Synthesis ofC- andP-Chiral Phosphoramidates

    Article • Journal of the American Chemical Society, October 2014, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  68. Umpolung Amide Synthesis Using Substoichiometric N-Iodosuccinimide (NIS) and Oxygen as a Terminal Oxidant

    Article • Organic Letters, September 2014, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  69. Alkene Diamination Using Electron-Rich Amines: Hypervalent Iodine-Promoted Inter-/Intramolecular C–N Bond Formation

    Article • Organic Letters, July 2014, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  70. Organocatalytic, Diastereo- and Enantioselective Synthesis of Nonsymmetric cis-Stilbene Diamines: A Platform for the Preparation of Single-Enantiomer cis-Imidazolines for Protein–Protein Inhibition

    Article • The Journal of Organic Chemistry, July 2014, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  71. 2,6-Bis[(4S)-4-isopropyloxazolin-2-yl]pyridine

    Article • May 2014, Wiley

    Professor Jeffrey N. Johnston

  72. Silyl Imine Electrophiles in Enantioselective Catalysis: A Rosetta Stone for Peptide Homologation, Enabling Diverse N-Protected Aryl Glycines from Aldehydes in Three Steps

    Article • Organic Letters, May 2014, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  73. ChemInform Abstract: Preparation of (-)-Nutlin-3 Using Enantioselective Organocatalysis at Decagram Scale.

    Article • ChemInform, March 2014, Wiley

    Professor Jeffrey N. Johnston

  74. Preparation of H,4PyrrolidineQuin-BAM (PBAM)

    Article • February 2014, Wiley

    Professor Jeffrey N. Johnston

  75. Preparation of (−)-Nutlin-3 Using Enantioselective Organocatalysis at Decagram Scale

    Article • The Journal of Organic Chemistry, November 2013, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  76. ChemInform Abstract: Enantioselective Synthesis of α-Oxy Amides via Umpolung Amide Synthesis.

    Article • ChemInform, February 2013, Wiley

    Professor Jeffrey N. Johnston

  77. VNI Cures Acute and Chronic Experimental Chagas Disease

    Article • The Journal of Infectious Diseases, January 2013, Oxford University Press (OUP)

    Professor Jeffrey N. Johnston

  78. Total Synthesis of the Lycopodium Alkaloid Serratezomine A Using Free Radical-Mediated Vinyl Amination to Prepare a β-Stannyl Enamine Linchpin

    Article • The Journal of Organic Chemistry, December 2012, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  79. Organocatalytic, Enantioselective Synthesis of VNI: A Robust Therapeutic Development Platform for Chagas, a Neglected Tropical Disease

    Article • Organic Letters, December 2012, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  80. Enantioselective Synthesis of α-Oxy Amides via Umpolung Amide Synthesis

    Article • Journal of the American Chemical Society, September 2012, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  81. ChemInform Abstract: Chiral Proton Catalysis of Secondary Nitroalkane Additions to Azomethine: Synthesis of a Potent GlyT1 Inhibitor.

    Article • ChemInform, August 2012, Wiley

    Professor Jeffrey N. Johnston

  82. ChemInform Abstract: Achiral Counterion Control of Enantioselectivity in a Broensted Acid-Catalyzed Iodolactonization.

    Article • ChemInform, August 2012, Wiley

    Professor Jeffrey N. Johnston

  83. Achiral Counterion Control of Enantioselectivity in a Brønsted Acid-Catalyzed Iodolactonization

    Article • Journal of the American Chemical Society, April 2012, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  84. Chiral proton catalysis of secondary nitroalkane additions to azomethine: synthesis of a potent GlyT1 inhibitor

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  85. Serratezomine A

    Article • January 2012, Springer Science + Business Media

    Professor Jeffrey N. Johnston

  86. Preparation of H,4 PyrrolidineQuin-BAM (PBAM)

    Article • Organic Syntheses, January 2012, Organic Syntheses

    Professor Jeffrey N. Johnston

  87. Discovery of competing anaerobic and aerobic pathways in umpolung amide synthesis allows for site-selective amide 18 O-labeling

    Article • Proceedings of the National Academy of Sciences, December 2011, Proceedings of the National Academy of Sciences

    Professor Jeffrey N. Johnston

  88. Preparation of Isopropyl 2-Diazoacetyl(Phenyl)Carbamate

    Article • November 2011, Wiley

    Professor Jeffrey N. Johnston

  89. Total Synthesis of the Chlorine-Containing Hapalindoles K, A, and G

    Article • Angewandte Chemie, July 2011, Wiley

    Professor Jeffrey N. Johnston

  90. Total Synthesis of the Chlorine-Containing Hapalindoles K, A, and G

    Article • Angewandte Chemie, July 2011, Wiley

    Professor Jeffrey N. Johnston

  91. ChemInform Abstract: Stereoselective Synthesis of Complex Polycyclic Aziridines (XI): Use of the Broensted Acid‐Catalyzed Aza‐Darzens Reaction to Prepare an Orthogonally Protected Mitomycin C Intermediate with Maximal Convergency.

    Article • ChemInform, June 2011, Wiley

    Professor Jeffrey N. Johnston

  92. ChemInform Abstract: A Chiral N-Phosphinyl Phosphoramide: Another Offspring for the Sage Phosphoric Acid Progenitor.

    Article • ChemInform, June 2011, Wiley

    Professor Jeffrey N. Johnston

  93. Origins of Selectivity in Brønsted Acid-Promoted Diazoalkane−Azomethine Reactions (The Aza-Darzens Aziridine Synthesis)

    Article • Organic Letters, April 2011, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  94. Ein chirales N-Phosphinylphosphoramid: ein weiterer Abkömmling der Phosphorsäure

    Article • Angewandte Chemie, February 2011, Wiley

    Professor Jeffrey N. Johnston

  95. A Chiral N-Phosphinyl Phosphoramide: Another Offspring for the Sage Phosphoric Acid Progenitor

    Article • Angewandte Chemie, February 2011, Wiley

    Professor Jeffrey N. Johnston

  96. Review of Recent Developments in Asymmetric Organocatalysis

    Article • Journal of the American Chemical Society, January 2011, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  97. Stereoselective synthesis of complex polycyclic aziridines: use of the Brønsted acid-catalyzed aza-Darzens reaction to prepare an orthogonally protected mitomycin C intermediate with maximal convergency

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  98. Catalytic, enantioselective synthesis of stilbene cis-diamines: A concise preparation of (−)-Nutlin-3, a potent p53/MDM2 inhibitor

    Article • Chemical Science, January 2011, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  99. Geometric Restraint Drives On- and Off-pathway Catalysis by the Escherichia coli Menaquinol:Fumarate Reductase

    Article • Journal of Biological Chemistry, January 2011, Elsevier

    Professor Jeffrey N. Johnston

  100. PREPARATION OF ISOPROPYL 2-DIAZOACETYL(PHENYL)CARBAMATE

    Article • Organic Syntheses, January 2011, Organic Syntheses

    Professor Jeffrey N. Johnston

  101. Brønsted acid-promoted azide–olefin [3 + 2] cycloadditions for the preparation of contiguous aminopolyols: The importance of disiloxane ring size to a diastereoselective, bidirectional approach to zwittermicin A

    Article • Beilstein Journal of Organic Chemistry, December 2010, Beilstein Institut

    Professor Jeffrey N. Johnston

  102. Chiral Brønsted Base-Promoted Nitroalkane Alkylation: Enantioselective Synthesis of sec -Alkyl-3-Substituted Indoles

    Article • Organic Letters, December 2010, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  103. Umpolung reactivity in amide and peptide synthesis

    Article • Nature, June 2010, Nature

    Professor Jeffrey N. Johnston

  104. ChemInform Abstract: Catalytic Enantioselective Michael Additions to Unsaturated Ester Derivatives Using Chiral Copper(II) Lewis Acid Complexes.

    Article • ChemInform, June 2010, Wiley

    Professor Jeffrey N. Johnston

  105. ChemInform Abstract: Stereocontrolled Elaboration of Natural (-)-Polycavernoside A, a Powerfully Toxic Metabolite of the Red Alga Polycavernosa tsudai.

    Article • ChemInform, June 2010, Wiley

    Professor Jeffrey N. Johnston

  106. ChemInform Abstract: To Protonate or Alkylate? Stereoselective Broensted Acid Catalysis of C-C Bond Formation Using Diazoalkanes

    Article • ChemInform, June 2010, Wiley

    Professor Jeffrey N. Johnston

  107. ChemInform Abstract: Nonconventional Carbon Additions to Azomethines. Aryl Amination/Indoline Synthesis by Direct Aryl Radical Addition to Azomethine Nitrogen.

    Article • ChemInform, May 2010, Wiley

    Professor Jeffrey N. Johnston

  108. ChemInform Abstract: Enantioselective and Diastereoselective Mukaiyama-Michael Reactions Catalyzed by Bis(oxazoline) Copper(II) Complexes.

    Article • ChemInform, May 2010, Wiley

    Professor Jeffrey N. Johnston

  109. ChemInform Abstract: Use of the Vicinal Element Effect for Regiochemical Control of Quinone Substitutions and Its Implication for Convergent Mitomycin Construction.

    Article • ChemInform, May 2010, Wiley

    Professor Jeffrey N. Johnston

  110. ChemInform Abstract: Broensted Acid Activation of α-Diazo Imide: A syn-Selective Glycolate Mannich Reaction.

    Article • ChemInform, March 2010, Wiley

    Professor Jeffrey N. Johnston

  111. To Protonate or Alkylate? Stereoselective Brønsted Acid Catalysis of CC Bond Formation Using Diazoalkanes

    Article • Angewandte Chemie, March 2010, Wiley

    Professor Jeffrey N. Johnston

  112. Protonierung oder Alkylierung? Stereoselektive Brønsted-Säure-katalysierte C-C-Verknüpfungen mit Diazoalkanen

    Article • Angewandte Chemie, March 2010, Wiley

    Professor Jeffrey N. Johnston

  113. Bifunctional Asymmetric Catalysis: Amplification of Brønsted Basicity Can Orthogonally Increase the Reactivity of a Chiral Brønsted Acid

    Article • Journal of the American Chemical Society, February 2010, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  114. ChemInform Abstract: Use of Comparative Triazolinium Triflate Fragmentation Rates as a Tool to Assay Relative Competency of Broensted Bases in N→N Proton Transfer.

    Article • ChemInform, December 2009, Wiley

    Professor Jeffrey N. Johnston

  115. Use of comparative triazolinium triflate fragmentation rates as a tool to assay relative competency of Brønsted bases in N→N proton transfer

    Article • Bioorganic & Medicinal Chemistry Letters, September 2009, Elsevier

    Professor Jeffrey N. Johnston

  116. ChemInform Abstract: Total Synthesis of the Lycopodium Alkaloid (+)-Serratezomine A.

    Article • ChemInform, July 2009, Wiley

    Professor Jeffrey N. Johnston

  117. Total Synthesis of the Lycopodium Alkaloid (+)-Serratezomine A

    Article • Journal of the American Chemical Society, March 2009, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  118. ChemInform Abstract: A Formal Enantioselective Acetate Mannich Reaction: The Nitro Functional Group as a Traceless Agent for Activation and Enantiocontrol in the Synthesis of β-Amino Acids.

    Article • ChemInform, March 2009, Wiley

    Professor Jeffrey N. Johnston

  119. ChemInform Abstract: A Diastereo- and Enantioselective Synthesis of α-Substituted anti-α,β-Diaminophosphonic Acid Derivatives.

    Article • ChemInform, January 2009, Wiley

    Professor Jeffrey N. Johnston

  120. Brønsted acid activation of α-diazo imide: a syn-selective glycolate Mannich reaction

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  121. ChemInform Abstract: A Diastereo- and Enantioselective Synthesis of α-Substituted syn-α,β-Diamino Acids.

    Article • ChemInform, September 2008, Wiley

    Professor Jeffrey N. Johnston

  122. A Formal Enantioselective Acetate Mannich Reaction: The Nitro Functional Group as a Traceless Agent for Activation and Enantiocontrol in the Synthesis of β-Amino Acids

    Article • Organic Letters, September 2008, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  123. ChemInform Abstract: Free Radical-Mediated Aryl Amination: Convergent Two- and Three-Component Couplings to Chiral 2,3-Disubstituted Indolines.

    Article • ChemInform, August 2008, Wiley

    Professor Jeffrey N. Johnston

  124. A Preparation of Enantiomerically Enriched Axially Chiral β-Diketimines: Synthesis of (−)- and (+)-IAN Amine

    Article • Organic Letters, June 2008, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  125. A Diastereo- and Enantioselective Synthesis of α-Substituted syn -α,β-Diamino Acids

    Article • Journal of the American Chemical Society, May 2008, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  126. ChemInform Abstract: Synthesis of the ABC- (I) and D-Ring Systems (II) of the Indole Alkaloid Ambiguine G (III).

    Article • ChemInform, April 2008, Wiley

    Professor Jeffrey N. Johnston

  127. Free Radical-Mediated Aryl Amination:  Convergent Two- and Three-Component Couplings to Chiral 2,3-Disubstituted Indolines

    Article • The Journal of Organic Chemistry, March 2008, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  128. On the Nature of Rate Acceleration in the Synthesis and Fragmentation of Triazolines by Brønsted Acid:  Secondary Catalysis by Water (Hydronium Triflate)

    Article • Journal of the American Chemical Society, January 2008, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  129. A diastereo- and enantioselective synthesis of α-substituted anti-α,β-diaminophosphonic acid derivatives

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  130. Synthesis of the ABC- and D-Ring Systems of the Indole Alkaloid Ambiguine G

    Article • Organic Letters, November 2007, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  131. Chiral Proton Catalysis: Enantioselective Broensted Acid Catalyzed Additions of Nitroacetic Acid Derivatives as Glycine Equivalents.

    Article • ChemInform, August 2007, Wiley

    Professor Jeffrey N. Johnston

  132. Chiral Proton Catalysis:  Enantioselective Brønsted Acid Catalyzed Additions of Nitroacetic Acid Derivatives as Glycine Equivalents

    Article • Journal of the American Chemical Society, March 2007, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  133. Synthesis of an Advanced Intermediate en Route to the Mitomycin Natural Products

    Article • Organic Letters, December 2006, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  134. Preparation of a protected phosphoramidon precursor via an H-Phosphonate coupling strategy

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Professor Jeffrey N. Johnston

  135. A Case Study in Biomimetic Total Synthesis: Polyolefin Carbocyclizations to Terpenes and Steroids

    Article • ChemInform, April 2006, Wiley

    Professor Jeffrey N. Johnston

  136. On the use of a Modified Latin Hypercube Sampling (MLHS) method in the estimation of a Mixed Logit Model for vehicle choice

    Article • Transportation Research Part B Methodological, February 2006, Elsevier

    Professor Jeffrey N. Johnston

  137. Chiral Proton Catalysis: pK a Determination for a BAM-HX Brønsted Acid

    Article • Synlett, January 2006, Thieme Publishing Group

    Professor Jeffrey N. Johnston

  138. A Case Study in Biomimetic Total Synthesis:  Polyolefin Carbocyclizations to Terpenes and Steroids

    Article • Chemical Reviews, December 2005, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  139. Broensted Acid-Promoted Olefin Aziridination and Formal anti-Aminohydroxylation.

    Article • ChemInform, June 2005, Wiley

    Professor Jeffrey N. Johnston

  140. Brønsted Acid-Promoted Olefin Aziridination and Formal a nti -Aminohydroxylation

    Article • Journal of the American Chemical Society, February 2005, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  141. Free Radical-Mediated Aryl Amination: A Practical Synthesis of ( R )- and ( S )-7-Azaindoline α-Amino Acid

    Article • Synthesis, January 2005, Thieme Publishing Group

    Professor Jeffrey N. Johnston

  142. A Remarkably Facile Zirconium(IV) → Aluminum(III) β-Diketiminate Transmetalation That Also Results in a More Active Olefin Polymerization Catalyst upon Activation

    Article • Organometallics, November 2004, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  143. The Broensted Acid Catalyzed Direct Aza-Darzens Synthesis of N-Alkyl cis-Aziridines.

    Article • ChemInform, June 2004, Wiley

    Professor Jeffrey N. Johnston

  144. IAN Amines:  Chiral C2-Symmetric Zirconium(IV) Complexes from Readily Modified Axially Chiral C1-Symmetric β-Diketimines

    Article • Organometallics, April 2004, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  145. Free Radical-Mediated Vinyl Amination: A Mild, General Pyrrolidinyl Enamine Synthesis.

    Article • ChemInform, March 2004, Wiley

    Professor Jeffrey N. Johnston

  146. Chiral Proton Catalysis:  A Catalytic Enantioselective Direct Aza-Henry Reaction

    Article • Journal of the American Chemical Society, March 2004, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  147. The Brønsted Acid-Catalyzed Direct Aza-Darzens Synthesis of N -Alkyl cis -Aziridines

    Article • Journal of the American Chemical Society, February 2004, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  148. Enantioenriched Axially Chiral b-Diketimines: Determination of the IAN-amine Barrier to Atrop- isomerization

    Article • Heterocycles, January 2004, Japan Institute of Heterocyclic Chemistry

    Professor Jeffrey N. Johnston

  149. Free radical-mediated vinyl amination: a mild, general pyrrolidinyl enamine synthesis

    Article • Tetrahedron, November 2003, Elsevier

    Professor Jeffrey N. Johnston

  150. The First Azacyclopentenyl Carbinyl Radical Isomerizations (ACCRI): Independent Use of Steric and Electronic (Polarization) Effects as Gating Elements.

    Article • ChemInform, October 2003, Wiley

    Professor Jeffrey N. Johnston

  151. Free Radical-Mediated Aryl Amination and Its Use in a Convergent [3 + 2] Strategy for Enantioselective Indoline α-Amino Acid Synthesis.

    Article • ChemInform, June 2003, Wiley

    Professor Jeffrey N. Johnston

  152. The First Azacyclopentenyl Carbinyl Radical Isomerizations (ACCRI):  Independent Use of Steric and Electronic (Polarization) Effects as Gating Elements

    Article • Journal of the American Chemical Society, May 2003, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  153. N-Propenoyl Camphor-10,2-sultam

    Article • April 2003, Wiley

    Professor Jeffrey N. Johnston

  154. N-Glyoxyloyl-(2R)-bornane-10,2-sultam

    Article • April 2003, Wiley

    Professor Jeffrey N. Johnston

  155. Free Radical Mediated Vinyl Amination: Access-to N,N-Dialkyl Enamines and Their β-Stannyl and β-Thio Derivatives.

    Article • ChemInform, April 2003, Wiley

    Professor Jeffrey N. Johnston

  156. Free Radical-Mediated Aryl Amination and Its Use in a Convergent [3 + 2] Strategy for Enantioselective Indoline α-Amino Acid Synthesis

    Article • Journal of the American Chemical Society, December 2002, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  157. Free Radical-Mediated Vinyl Amination:  Access to N,N-Dialkyl Enamines and Their β-Stannyl and β-Thio Derivatives

    Article • Organic Letters, November 2002, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  158. 2,6-Bis[(4S)-4-isopropyloxazolin-2-yl]pyridine

    Article • October 2002, Wiley

    Professor Jeffrey N. Johnston

  159. IAN-Amines: Direct Entry to a ChiralC2-Symmetric Zirconium(IV)β-Diketimine Complex

    Article • Angewandte Chemie, January 2002, Wiley

    Professor Jeffrey N. Johnston

  160. IAN-Amines: Direct Entry to a Chiral C2-Symmetric Zirconium(IV) β-Diketimine Complex Financial support has been provided by a GAANN Fellowship to S.B.C. (2001) and by Indiana University. IAN-amines are amines that are derived from Isoquinoline and 2-Am...

    Article • Angewandte Chemie, January 2002, Wiley

    Professor Jeffrey N. Johnston

  161. Use of the V icinal Element Effect for Regiochemical Control of Quinone Substitutions and Its Implication for Convergent Mitomycin Construction

    Article • Organic Letters, November 2001, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  162. Enantioselective and Diastereoselective Mukaiyama−Michael Reactions Catalyzed by Bis(oxazoline) Copper(II) Complexes

    Article • Journal of the American Chemical Society, April 2001, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  163. Lithium Aluminum Hydride-Cerium(III) Chloride

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  164. Chromium(VI) Oxide-3,5-Dimethylpyrazole

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  165. Lithium Aluminum Hydride-Cobalt(II) Chloride

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  166. Diphenylacetylene

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  167. Article • Organic Letters, April 2001, CrossRef Test Account

    Professor Jeffrey N. Johnston

  168. Nonconventional Carbon Additions to Azomethines. Aryl Amination/Indoline Synthesis by Direct Aryl Radical Addition to Azomethine Nitrogen

    Article • Organic Letters, April 2001, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  169. Stereocontrolled Elaboration of Natural (−)-Polycavernoside A, a Powerfully Toxic Metabolite of the Red Alga Polycavernosa tsudai

    Article • Journal of the American Chemical Society, December 1999, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  170. Catalytic Enantioselective Michael Additions to Unsaturated Ester Derivatives Using Chiral Copper(II) Lewis Acid Complexes

    Article • Organic Letters, September 1999, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  171. Stereochemical Models for the Enantiocontrolled Construction of Fully Functionalized C Rings via Intramolecular Aldolization in Advanced Precursors to Paclitaxel

    Article • The Journal of Organic Chemistry, October 1998, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  172. New Extensions of the Anionic Oxy-Cope/Intramolecular SN' Reaction Cascade

    Article • Synthetic Communications, April 1998, Taylor & Francis

    Professor Jeffrey N. Johnston

  173. Application of an S → O Allylic Transposition in the Context of a Bridgehead Olefinic System. New Opportunities for the Structural Modification of Bicyclo[6.2.1]undecanes via Transannular Ring Closure

    Article • The Journal of Organic Chemistry, January 1998, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  174. Single Stereodifferentiation Associated with Carbon Atom Insertion during the Oxonium Ion-Initiated Pinacol Rearrangement of Dihydrofuranyl and Dihydropyranyl Carbinols

    Article • The Journal of Organic Chemistry, March 1997, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  175. Synthesis and biological evaluation of flavonoids and related compounds as gastroprotective agents

    Article • Bioorganic & Medicinal Chemistry Letters, April 1996, Elsevier

    Professor Jeffrey N. Johnston

  176. Studies directed toward the total synthesis of polycavernoside A. Enantioselective synthesis of the disaccharide component

    Article • Tetrahedron Letters, June 1995, Elsevier

    Professor Jeffrey N. Johnston

  177. Bromonitromethane

    Article • Wiley

    Professor Jeffrey N. Johnston