All Stories

  1. A one-pot amidation of primary nitroalkanes

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  2. ChemInform Abstract: Oxidative Inter-/Intermolecular Alkene Diamination of Hydroxy Styrenes with Electron-Rich Amines.

    Article • ChemInform, September 2015, Wiley

    Professor Jeffrey N. Johnston

  3. Abstract B12: Synergistic anticancer activity of Aurora A kinase and MDM2 antagonists in melanoma

    Article • Cancer Research, July 2015, American Association for Cancer Research (AACR)

    Professor Jeffrey N. Johnston

  4. ChemInform Abstract: Enantioselective Synthesis of D-α-Amino Amides from Aliphatic Aldehydes.

    Article • ChemInform, July 2015, Wiley

    Professor Jeffrey N. Johnston

  5. Oxidative Inter-/Intermolecular Alkene Diamination of Hydroxy Styrenes with Electron-Rich Amines

    Article • Organic Letters, May 2015, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  6. ChemInform Abstract: Broensted Acid Catalyzed Phosphoramidic Acid Additions to Alkenes: Diastereo- and Enantioselective Halogenative Cyclizations for the synthesis of C- and P-Chiral Phosphoramidates.

    Article • ChemInform, April 2015, Wiley

    Professor Jeffrey N. Johnston

  7. ChemInform Abstract: Umpolung Amide Synthesis Using Substoichiometric N-Iodosuccinimide (NIS) and Oxygen as a Terminal Oxidant.

    Article • ChemInform, February 2015, Wiley

    Professor Jeffrey N. Johnston

  8. Enantioselective synthesis of d-α-amino amides from aliphatic aldehydes

    Article • Chemical Science, January 2015, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  9. ChemInform Abstract: Alkene Diamination Using Electron-Rich Amines: Hypervalent Iodine-Promoted Inter-/Intramolecular C-N Bond Formation.

    Article • ChemInform, December 2014, Wiley

    Professor Jeffrey N. Johnston

  10. ChemInform Abstract: Silyl Imine Electrophiles in Enantioselective Catalysis: A Rosetta Stone for Peptide Homologation, Enabling Diverse N-Protected Aryl Glycines from Aldehydes in Three Steps.

    Article • ChemInform, November 2014, Wiley

    Professor Jeffrey N. Johnston

  11. Alkene Diamination Using Electron-Rich Amines: Hypervalent Iodine-Promoted Inter-/Intramolecular C–N Bond Formation

    Article • Organic Letters, July 2014, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  12. 2,6-Bis[(4S)-4-isopropyloxazolin-2-yl]pyridine

    Article • May 2014, Wiley

    Professor Jeffrey N. Johnston

  13. ChemInform Abstract: Preparation of (-)-Nutlin-3 Using Enantioselective Organocatalysis at Decagram Scale.

    Article • ChemInform, March 2014, Wiley

    Professor Jeffrey N. Johnston

  14. Preparation of H,4PyrrolidineQuin-BAM (PBAM)

    Article • February 2014, Wiley

    Professor Jeffrey N. Johnston

  15. Preparation of (−)-Nutlin-3 Using Enantioselective Organocatalysis at Decagram Scale

    Article • The Journal of Organic Chemistry, November 2013, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  16. ChemInform Abstract: Enantioselective Synthesis of α-Oxy Amides via Umpolung Amide Synthesis.

    Article • ChemInform, February 2013, Wiley

    Professor Jeffrey N. Johnston

  17. Enantioselective Synthesis of α-Oxy Amides via Umpolung Amide Synthesis

    Article • Journal of the American Chemical Society, September 2012, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  18. ChemInform Abstract: Chiral Proton Catalysis of Secondary Nitroalkane Additions to Azomethine: Synthesis of a Potent GlyT1 Inhibitor.

    Article • ChemInform, August 2012, Wiley

    Professor Jeffrey N. Johnston

  19. ChemInform Abstract: Achiral Counterion Control of Enantioselectivity in a Broensted Acid-Catalyzed Iodolactonization.

    Article • ChemInform, August 2012, Wiley

    Professor Jeffrey N. Johnston

  20. Achiral Counterion Control of Enantioselectivity in a Brønsted Acid-Catalyzed Iodolactonization

    Article • Journal of the American Chemical Society, April 2012, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  21. Chiral proton catalysis of secondary nitroalkane additions to azomethine: synthesis of a potent GlyT1 inhibitor

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  22. Serratezomine A

    Article • January 2012, Springer Science + Business Media

    Professor Jeffrey N. Johnston

  23. Preparation of Isopropyl 2-Diazoacetyl(Phenyl)Carbamate

    Article • November 2011, Wiley

    Professor Jeffrey N. Johnston

  24. Total Synthesis of the Chlorine-Containing Hapalindoles K, A, and G

    Article • Angewandte Chemie, July 2011, Wiley

    Professor Jeffrey N. Johnston

  25. Total Synthesis of the Chlorine-Containing Hapalindoles K, A, and G

    Article • Angewandte Chemie International Edition, July 2011, Wiley

    Professor Jeffrey N. Johnston

  26. ChemInform Abstract: A Chiral N-Phosphinyl Phosphoramide: Another Offspring for the Sage Phosphoric Acid Progenitor.

    Article • ChemInform, June 2011, Wiley

    Professor Jeffrey N. Johnston

  27. Origins of Selectivity in Brønsted Acid-Promoted Diazoalkane−Azomethine Reactions (The Aza-Darzens Aziridine Synthesis)

    Article • Organic Letters, April 2011, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  28. Ein chirales N-Phosphinylphosphoramid: ein weiterer Abkömmling der Phosphorsäure

    Article • Angewandte Chemie, February 2011, Wiley

    Professor Jeffrey N. Johnston

  29. A Chiral N-Phosphinyl Phosphoramide: Another Offspring for the Sage Phosphoric Acid Progenitor

    Article • Angewandte Chemie International Edition, February 2011, Wiley

    Professor Jeffrey N. Johnston

  30. Catalytic, enantioselective synthesis of stilbene cis-diamines: A concise preparation of (−)-Nutlin-3, a potent p53/MDM2 inhibitor

    Article • Chemical Science, January 2011, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  31. Chiral Brønsted Base-Promoted Nitroalkane Alkylation: Enantioselective Synthesis of sec -Alkyl-3-Substituted Indoles

    Article • Organic Letters, December 2010, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  32. Umpolung reactivity in amide and peptide synthesis

    Article • Nature, June 2010, Nature

    Professor Jeffrey N. Johnston

  33. ChemInform Abstract: Catalytic Enantioselective Michael Additions to Unsaturated Ester Derivatives Using Chiral Copper(II) Lewis Acid Complexes.

    Article • ChemInform, June 2010, Wiley

    Professor Jeffrey N. Johnston

  34. ChemInform Abstract: Stereocontrolled Elaboration of Natural (-)-Polycavernoside A, a Powerfully Toxic Metabolite of the Red Alga Polycavernosa tsudai.

    Article • ChemInform, June 2010, Wiley

    Professor Jeffrey N. Johnston

  35. ChemInform Abstract: To Protonate or Alkylate? Stereoselective Broensted Acid Catalysis of C-C Bond Formation Using Diazoalkanes

    Article • ChemInform, June 2010, Wiley

    Professor Jeffrey N. Johnston

  36. ChemInform Abstract: Nonconventional Carbon Additions to Azomethines. Aryl Amination/Indoline Synthesis by Direct Aryl Radical Addition to Azomethine Nitrogen.

    Article • ChemInform, May 2010, Wiley

    Professor Jeffrey N. Johnston

  37. ChemInform Abstract: Enantioselective and Diastereoselective Mukaiyama-Michael Reactions Catalyzed by Bis(oxazoline) Copper(II) Complexes.

    Article • ChemInform, May 2010, Wiley

    Professor Jeffrey N. Johnston

  38. ChemInform Abstract: Use of the Vicinal Element Effect for Regiochemical Control of Quinone Substitutions and Its Implication for Convergent Mitomycin Construction.

    Article • ChemInform, May 2010, Wiley

    Professor Jeffrey N. Johnston

  39. ChemInform Abstract: Broensted Acid Activation of α-Diazo Imide: A syn-Selective Glycolate Mannich Reaction.

    Article • ChemInform, March 2010, Wiley

    Professor Jeffrey N. Johnston

  40. To Protonate or Alkylate? Stereoselective Brønsted Acid Catalysis of CC Bond Formation Using Diazoalkanes

    Article • Angewandte Chemie International Edition, March 2010, Wiley

    Professor Jeffrey N. Johnston

  41. Protonierung oder Alkylierung? Stereoselektive Brønsted-Säure-katalysierte C-C-Verknüpfungen mit Diazoalkanen

    Article • Angewandte Chemie, March 2010, Wiley

    Professor Jeffrey N. Johnston

  42. ChemInform Abstract: Total Synthesis of the Lycopodium Alkaloid (+)-Serratezomine A.

    Article • ChemInform, July 2009, Wiley

    Professor Jeffrey N. Johnston

  43. Total Synthesis of the Lycopodium Alkaloid (+)-Serratezomine A

    Article • Journal of the American Chemical Society, March 2009, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  44. ChemInform Abstract: A Formal Enantioselective Acetate Mannich Reaction: The Nitro Functional Group as a Traceless Agent for Activation and Enantiocontrol in the Synthesis of β-Amino Acids.

    Article • ChemInform, March 2009, Wiley

    Professor Jeffrey N. Johnston

  45. ChemInform Abstract: A Diastereo- and Enantioselective Synthesis of α-Substituted anti-α,β-Diaminophosphonic Acid Derivatives.

    Article • ChemInform, January 2009, Wiley

    Professor Jeffrey N. Johnston

  46. Brønsted acid activation of α-diazo imide: a syn-selective glycolate Mannich reaction

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  47. ChemInform Abstract: A Diastereo- and Enantioselective Synthesis of α-Substituted syn-α,β-Diamino Acids.

    Article • ChemInform, September 2008, Wiley

    Professor Jeffrey N. Johnston

  48. ChemInform Abstract: Free Radical-Mediated Aryl Amination: Convergent Two- and Three-Component Couplings to Chiral 2,3-Disubstituted Indolines.

    Article • ChemInform, August 2008, Wiley

    Professor Jeffrey N. Johnston

  49. A Preparation of Enantiomerically Enriched Axially Chiral β-Diketimines: Synthesis of (−)- and (+)-IAN Amine

    Article • Organic Letters, June 2008, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  50. A Diastereo- and Enantioselective Synthesis of α-Substituted syn -α,β-Diamino Acids

    Article • Journal of the American Chemical Society, May 2008, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  51. ChemInform Abstract: Synthesis of the ABC- (I) and D-Ring Systems (II) of the Indole Alkaloid Ambiguine G (III).

    Article • ChemInform, April 2008, Wiley

    Professor Jeffrey N. Johnston

  52. A diastereo- and enantioselective synthesis of α-substituted anti-α,β-diaminophosphonic acid derivatives

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Professor Jeffrey N. Johnston

  53. Synthesis of the ABC- and D-Ring Systems of the Indole Alkaloid Ambiguine G

    Article • Organic Letters, November 2007, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  54. Chiral Proton Catalysis: Enantioselective Broensted Acid Catalyzed Additions of Nitroacetic Acid Derivatives as Glycine Equivalents.

    Article • ChemInform, August 2007, Wiley

    Professor Jeffrey N. Johnston

  55. Synthesis of an Advanced Intermediate en Route to the Mitomycin Natural Products

    Article • Organic Letters, December 2006, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  56. Preparation of a protected phosphoramidon precursor via an H-Phosphonate coupling strategy

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Professor Jeffrey N. Johnston

  57. A Case Study in Biomimetic Total Synthesis: Polyolefin Carbocyclizations to Terpenes and Steroids

    Article • ChemInform, April 2006, Wiley

    Professor Jeffrey N. Johnston

  58. Chiral Proton Catalysis: pK a Determination for a BAM-HX Brønsted Acid

    Article • Synlett, January 2006, Thieme Publishing Group

    Professor Jeffrey N. Johnston

  59. A Case Study in Biomimetic Total Synthesis:  Polyolefin Carbocyclizations to Terpenes and Steroids

    Article • Chemical Reviews, December 2005, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  60. Broensted Acid-Promoted Olefin Aziridination and Formal anti-Aminohydroxylation.

    Article • ChemInform, June 2005, Wiley

    Professor Jeffrey N. Johnston

  61. Brønsted Acid-Promoted Olefin Aziridination and Formal a nti -Aminohydroxylation

    Article • Journal of the American Chemical Society, February 2005, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  62. Free Radical-Mediated Aryl Amination: A Practical Synthesis of ( R )- and ( S )-7-Azaindoline α-Amino Acid

    Article • Synthesis, January 2005, Thieme Publishing Group

    Professor Jeffrey N. Johnston

  63. The Broensted Acid Catalyzed Direct Aza-Darzens Synthesis of N-Alkyl cis-Aziridines.

    Article • ChemInform, June 2004, Wiley

    Professor Jeffrey N. Johnston

  64. Free Radical-Mediated Vinyl Amination: A Mild, General Pyrrolidinyl Enamine Synthesis.

    Article • ChemInform, March 2004, Wiley

    Professor Jeffrey N. Johnston

  65. Chiral Proton Catalysis:  A Catalytic Enantioselective Direct Aza-Henry Reaction

    Article • Journal of the American Chemical Society, March 2004, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  66. The Brønsted Acid-Catalyzed Direct Aza-Darzens Synthesis of N -Alkyl cis -Aziridines

    Article • Journal of the American Chemical Society, February 2004, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  67. Enantioenriched Axially Chiral b-Diketimines: Determination of the IAN-amine Barrier to Atrop- isomerization

    Article • Heterocycles, January 2004, Japan Institute of Heterocyclic Chemistry

    Professor Jeffrey N. Johnston

  68. Free radical-mediated vinyl amination: a mild, general pyrrolidinyl enamine synthesis

    Article • Tetrahedron, November 2003, Elsevier

    Professor Jeffrey N. Johnston

  69. The First Azacyclopentenyl Carbinyl Radical Isomerizations (ACCRI): Independent Use of Steric and Electronic (Polarization) Effects as Gating Elements.

    Article • ChemInform, October 2003, Wiley

    Professor Jeffrey N. Johnston

  70. Free Radical-Mediated Aryl Amination and Its Use in a Convergent [3 + 2] Strategy for Enantioselective Indoline α-Amino Acid Synthesis.

    Article • ChemInform, June 2003, Wiley

    Professor Jeffrey N. Johnston

  71. N-Propenoyl Camphor-10,2-sultam

    Article • April 2003, Wiley

    Professor Jeffrey N. Johnston

  72. N-Glyoxyloyl-(2R)-bornane-10,2-sultam

    Article • April 2003, Wiley

    Professor Jeffrey N. Johnston

  73. Free Radical Mediated Vinyl Amination: Access-to N,N-Dialkyl Enamines and Their β-Stannyl and β-Thio Derivatives.

    Article • ChemInform, April 2003, Wiley

    Professor Jeffrey N. Johnston

  74. 2,6-Bis[(4S)-4-isopropyloxazolin-2-yl]pyridine

    Article • October 2002, Wiley

    Professor Jeffrey N. Johnston

  75. IAN-Amines: Direct Entry to a ChiralC2-Symmetric Zirconium(IV)β-Diketimine Complex

    Article • Angewandte Chemie, January 2002, Wiley

    Professor Jeffrey N. Johnston

  76. Use of the V icinal Element Effect for Regiochemical Control of Quinone Substitutions and Its Implication for Convergent Mitomycin Construction

    Article • Organic Letters, November 2001, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  77. Lithium Aluminum Hydride-Cerium(III) Chloride

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  78. Chromium(VI) Oxide-3,5-Dimethylpyrazole

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  79. Lithium Aluminum Hydride-Cobalt(II) Chloride

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  80. Diphenylacetylene

    Article • April 2001, Wiley

    Professor Jeffrey N. Johnston

  81. Nonconventional Carbon Additions to Azomethines. Aryl Amination/Indoline Synthesis by Direct Aryl Radical Addition to Azomethine Nitrogen

    Article • Organic Letters, April 2001, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  82. Catalytic Enantioselective Michael Additions to Unsaturated Ester Derivatives Using Chiral Copper(II) Lewis Acid Complexes

    Article • Organic Letters, September 1999, American Chemical Society (ACS)

    Professor Jeffrey N. Johnston

  83. Synthesis and biological evaluation of flavonoids and related compounds as gastroprotective agents

    Article • Bioorganic & Medicinal Chemistry Letters, April 1996, Elsevier

    Professor Jeffrey N. Johnston

  84. Studies directed toward the total synthesis of polycavernoside A. Enantioselective synthesis of the disaccharide component

    Article • Tetrahedron Letters, June 1995, Elsevier

    Professor Jeffrey N. Johnston

  85. Bromonitromethane

    Article • Wiley

    Professor Jeffrey N. Johnston