All Stories

  1. The Yersiniabactin-Associated ATP Binding Cassette Proteins YbtP and YbtQ Enhance Escherichia coli Fitness during High-Titer Cystitis

    Article • Infection and Immunity, February 2016, ASM Journals

    Dr Jeffrey P Henderson

  2. Metal selectivity by the virulence-associated yersiniabactin metallophore system

    Article • Metallomics, January 2015, Oxford University Press (OUP)

    Dr Jeffrey P Henderson

  3. Metabolomic Analysis of Siderophore Cheater Mutants Reveals Metabolic Costs of Expression in Uropathogenic Escherichia coli

    Article • Journal of Proteome Research, March 2014, American Chemical Society (ACS)

    Dr Jeffrey P Henderson

  4. Cupric Yersiniabactin Is a Virulence-Associated Superoxide Dismutase Mimic

    Article • ACS Chemical Biology, February 2014, American Chemical Society (ACS)

    Dr Jeffrey P Henderson

  5. The Bacterial Amyloid Curli Is Associated with Urinary Source Bloodstream Infection

    Article • PLoS ONE, January 2014, PLOS

    Dr Jeffrey P Henderson

  6. Pathogenic adaptations to host-derived antibacterial copper

    Article • Frontiers in Cellular and Infection Microbiology, January 2014, Frontiers

    Dr Jeffrey P Henderson

  7. Vancomycin resistance has no influence on outcomes of enterococcal bacteriuria

    Article • Journal of Hospital Infection, November 2013, Elsevier

    Dr Jeffrey P Henderson

  8. Weekend diagnosis of Escherichia coli urinary tract infection does not predict poor outcome

    Article • Epidemiology and Infection, September 2013, Cambridge University Press

    Dr Jeffrey P Henderson

  9. Escherichia coli Biofilms Have an Organized and Complex Extracellular Matrix Structure

    Article • mBio, September 2013, ASM Journals

    Dr Jeffrey P Henderson

  10. Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital

    Article • BMC Infectious Diseases, May 2013, Springer Science + Business Media

    Dr Jeffrey P Henderson

  11. Genomic Diversity and Fitness of E. coli Strains Recovered from the Intestinal and Urinary Tracts of Women with Recurrent Urinary Tract Infection

    Article • Science Translational Medicine, May 2013, American Association for the Advancement of Science

    Dr Jeffrey P Henderson

  12. A well known siderophore binds copper during human infections

    Article • Nature Chemical Biology, July 2012, Springer Science + Business Media

    Dr Jeffrey P Henderson

  13. Combinatorial Small-Molecule Therapy Prevents Uropathogenic Escherichia coli Catheter-Associated Urinary Tract Infections in Mice

    Article • Antimicrobial Agents and Chemotherapy, June 2012, ASM Journals

    Dr Jeffrey P Henderson

  14. Structural engineering of a phage lysin that targets Gram-negative pathogens

    Article • Proceedings of the National Academy of Sciences, June 2012, Proceedings of the National Academy of Sciences

    Dr Jeffrey P Henderson

  15. Both Host and Pathogen Factors Predispose to Escherichia coli Urinary-Source Bacteremia in Hospitalized Patients

    Article • Clinical Infectious Diseases, March 2012, Oxford University Press (OUP)

    Dr Jeffrey P Henderson

  16. Yersinia High Pathogenicity Island Genes Modify the Escherichia coli Primary Metabolome Independently of Siderophore Production

    Article • Journal of Proteome Research, December 2011, American Chemical Society (ACS)

    Dr Jeffrey P Henderson

  17. Treatment and Prevention of Urinary Tract Infection with Orally Active FimH Inhibitors

    Article • Science Translational Medicine, November 2011, American Association for the Advancement of Science

    Dr Jeffrey P Henderson

  18. Not All Nosocomial Escherichia coli Bacteriurias Are Catheter Associated

    Article • Infection Control and Hospital Epidemiology, November 2011, Cambridge University Press

    Dr Jeffrey P Henderson

  19. A central metabolic circuit controlled by QseC in pathogenic Escherichia coli

    Article • Molecular Microbiology, May 2011, Wiley

    Dr Jeffrey P Henderson

  20. Development of an integrated metabolomic profiling approach for infectious diseases research

    Article • The Analyst, January 2011, Royal Society of Chemistry

    Dr Jeffrey P Henderson

  21. Quantitative Metabolomics Reveals an Epigenetic Blueprint for Iron Acquisition in Uropathogenic Escherichia coli

    Article • PLoS Pathogens, February 2009, PLOS

    Dr Jeffrey P Henderson

  22. 8-Nitroxanthine, a product of myeloperoxidase, peroxynitrite, and activated human neutrophils, enhances generation of superoxide by xanthine oxidase

    Article • Archives of Biochemistry and Biophysics, October 2003, Elsevier

    Dr Jeffrey P Henderson

  23. Identification and quantification of mutagenic halogenated cytosines by gas chromatography, fast atom bombardment, and electrospray ionization tandem mass spectrometry

    Article • Analytical Biochemistry, June 2003, Elsevier

    Dr Jeffrey P Henderson

  24. Phagocytes Produce 5-Chlorouracil and 5-Bromouracil, Two Mutagenic Products of Myeloperoxidase, in Human Inflammatory Tissue

    Article • Journal of Biological Chemistry, April 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jeffrey P Henderson

  25. Myeloperoxidase and Eosinophil Peroxidase: Phagocyte Enzymes for Halogenation in Humans

    Article • January 2003, Springer Science + Business Media

    Dr Jeffrey P Henderson

  26. Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis

    Article • Proceedings of the National Academy of Sciences, October 2001, Proceedings of the National Academy of Sciences

    Dr Jeffrey P Henderson

  27. Bromination of deoxycytidine by eosinophil peroxidase: A mechanism for mutagenesis by oxidative damage of nucleotide precursors

    Article • Proceedings of the National Academy of Sciences, February 2001, Proceedings of the National Academy of Sciences

    Dr Jeffrey P Henderson

  28. The Eosinophil Peroxidase-Hydrogen Peroxide-Bromide System of Human Eosinophils Generates 5-Bromouracil, a Mutagenic Thymine Analogue †

    Article • Biochemistry, February 2001, American Chemical Society (ACS)

    Dr Jeffrey P Henderson

  29. Production of Brominating Intermediates by Myeloperoxidase: A TRANSHALOGENATION PATHWAY FOR GENERATING MUTAGENIC NUCLEOBASES DURING INFLAMMATION

    Article • Journal of Biological Chemistry, November 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jeffrey P Henderson

  30. Chlorination of nucleobases, RNA and DNA by myeloperoxidase: a pathway for cytotoxicity and mutagenesis by activated phagocytes

    Article • Redox Report, December 1999, Taylor & Francis

    Dr Jeffrey P Henderson

  31. Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Produces 5-Chlorocytosine in Bacterial RNA

    Article • Journal of Biological Chemistry, November 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jeffrey P Henderson

  32. 8-Nitro-2‘-deoxyguanosine, a Specific Marker of Oxidation by Reactive Nitrogen Species, Is Generated by the Myeloperoxidase−Hydrogen Peroxide−Nitrite System of Activated Human Phagocytes †

    Article • Biochemistry, February 1999, American Chemical Society (ACS)

    Dr Jeffrey P Henderson

  33. 8-nitro-2′-deoxyguanosine is generated by the myeloperoxidase-H2O2-nitrite system of activated human phagocytes

    Article • Free Radical Biology and Medicine, January 1998, Elsevier

    Dr Jeffrey P Henderson

  34. Hyperglycemia results in an increase in myocardial interstitial glucose and glucose uptake during ischemia

    Article • Metabolism, May 1996, Elsevier

    Dr Jeffrey P Henderson