All Stories

  1. P38  MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism

    Article • Human Molecular Genetics, May 2014, Oxford University Press (OUP)

    Jason Karch

  2. c-kit+ cells minimally contribute cardiomyocytes to the heart

    Article • Nature, May 2014, Springer Science + Business Media

    Jason Karch

  3. Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy

    Article • Cell Death and Differentiation, March 2014, Springer Science + Business Media

    Jason Karch

  4. Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

    Article • eLife, August 2013, eLife

    Jason Karch

  5. Is p53 the Long-Sought Molecular Trigger for Cyclophilin D–Regulated Mitochondrial Permeability Transition Pore Formation and Necrosis?

    Article • Circulation Research, October 2012, Wolters Kluwer Health

    Jason Karch

  6. Cyclin D1 Is a Selective Modifier of Androgen-dependent Signaling and Androgen Receptor Function

    Article • Journal of Biological Chemistry, January 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jason Karch, Dr Clay Comstock

  7. Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

    Article • Journal of Clinical Investigation, October 2010, American Society for Clinical Investigation

    Jason Karch

  8. Cyclin D1 Splice Variants: Polymorphism, Risk, and Isoform-Specific Regulation in Prostate Cancer

    Article • Clinical Cancer Research, August 2009, American Association for Cancer Research (AACR)

    Jason Karch, Dr Clay Comstock