All Stories

  1. Identification of an IgG CDR sequence contributing to co-purification of the host cell protease cathepsin D

    Article • Biotechnology Progress, November 2016, Wiley

    Dr Jared S Bee

  2. Generation and Characterization of an IgG4 Monomeric Fc Platform

    Article • PLoS ONE, August 2016, PLOS

    Dr Jared S Bee

  3. Fate of Multimeric Oligomers, Submicron, and Micron Size Aggregates of Monoclonal Antibodies Upon Subcutaneous Injection in Mice

    Article • Journal of Pharmaceutical Sciences, May 2016, Elsevier

    Dr Jared S Bee

  4. Trace levels of the CHO host cell protease cathepsin D caused particle formation in a monoclonal antibody product

    Article • Biotechnology Progress, August 2015, Wiley

    Dr Jared S Bee

  5. Technical Decision Making with Higher Order Structure Data: Impact of a Formulation Change on the Higher Order Structure and Stability of a mAb

    Article • Journal of Pharmaceutical Sciences, April 2015, Elsevier

    Dr Jared S Bee

  6. Gelation of a Monoclonal Antibody at the Silicone Oil–Water Interface and Subsequent Rupture of the Interfacial Gel Results in Aggregation and Particle Formation

    Article • Journal of Pharmaceutical Sciences, April 2015, Elsevier

    Dr Jared S Bee

  7. Characterization of Monoclonal Antibody Aggregates and Emerging Technologies

    Article • January 2015, American Chemical Society (ACS)

    Dr Jared S Bee

  8. Characterization of the Initial Level and Migration of Silicone Oil Lubricant in Empty Prefilled Syringes for Biologics Using Infrared Spectroscopy

    Article • PDA Journal of Pharmaceutical Science and Technology, September 2014, Parenteral Drug Association, Inc.

    Dr Jared S Bee

  9. Protein Aggregation and Particle Formation in Prefilled Glass Syringes

    Article • Journal of Pharmaceutical Sciences, June 2014, Elsevier

    Dr Jared S Bee, theodore Randolph

  10. Partial Unfolding of a Monoclonal Antibody: Role of a Single Domain in Driving Protein Aggregation

    Article • Biochemistry, May 2014, American Chemical Society (ACS)

    Dr Jared S Bee

  11. Ionic Strength Affects Tertiary Structure and Aggregation Propensity of a Monoclonal Antibody Adsorbed to Silicone Oil–Water Interfaces

    Article • Journal of Pharmaceutical Sciences, February 2013, Elsevier

    Dr Jared S Bee

  12. The future of protein particle characterization and understanding its potential to diminish the immunogenicity of biopharmaceuticals: A shared perspective

    Article • Journal of Pharmaceutical Sciences, October 2012, Elsevier

    Dr Jared S Bee

  13. Computational fluid dynamics (CFD) insights into agitation stress methods in biopharmaceutical development

    Article • International Journal of Pharmaceutics, February 2012, Elsevier

    Dr Jared S Bee

  14. Production of particles of therapeutic proteins at the air–water interface during compression/dilation cycles

    Article • Soft Matter, January 2012, Royal Society of Chemistry

    Dr Jared S Bee

  15. Effects of Surfaces and Leachables on the Stability of Biopharmaceuticals

    Article • Journal of Pharmaceutical Sciences, October 2011, Elsevier

    Dr Jared S Bee

  16. Aggregation of a monoclonal antibody induced by adsorption to stainless steel

    Article • Biotechnology and Bioengineering, January 2010, Wiley

    Dr Jared S Bee

  17. Precipitation of a Monoclonal Antibody by Soluble Tungsten

    Article • Journal of Pharmaceutical Sciences, September 2009, Elsevier

    Dr Jared S Bee

  18. Monoclonal antibody interactions with micro- and nanoparticles: Adsorption, aggregation, and accelerated stress studies

    Article • Journal of Pharmaceutical Sciences, September 2009, Elsevier

    Dr Jared S Bee

  19. Response of a concentrated monoclonal antibody formulation to high shear

    Article • Biotechnology and Bioengineering, August 2009, Wiley

    Dr Jared S Bee

  20. Variable Dimensionality in the Uranium Fluoride/2-Methyl-Piperazine System:  Syntheses and Structures of UFO-5, -6, and -7; Zero-, One-, and Two-Dimensional Materials with Unprecedented Topologies

    Article • Journal of the American Chemical Society, February 1999, American Chemical Society (ACS)

    Dr Jared S Bee