All Stories

  1. Development of Sustainable Biocatalytic Furfurylamine Production in a Magnetic Field-Assisted Microfluidic Reactor

    Article • ACS Sustainable Chemistry & Engineering, September 2025, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  2. Transition Metal‐Free Ortho‐Deuteration of Electron‐Deficient N‐Heteroarenes

    Article • European Journal of Organic Chemistry, August 2025, Wiley

    Prof. Dr. Janez Kosmrlj

  3. Sustainable synthetic routes to deuterium-labelled organic compounds using immobilized and recyclable (bio)catalysts

    Article • Green Synthesis and Catalysis, February 2025, Elsevier

    Prof. Dr. Janez Kosmrlj

  4. Photophysics of Molecular Probes for Amyloid-β Detection: Computational Insights into the Roles of Probe Linker and Functional Groups

    Article • The Journal of Physical Chemistry A, August 2024, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  5. The Versatile and Strategic O-Carbamate Directed Metalation Group in the Synthesis of Aromatic Molecules: An Update

    Article • Chemical Reviews, June 2024, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  6. Probing Alzheimer's pathology: Exploring the next generation of FDDNP analogues for amyloid β detection

    Article • Biomedicine & Pharmacotherapy, June 2024, Elsevier

    Prof. Dr. Janez Kosmrlj

  7. Piperidine and piperazine analogs in action: zinc(ii)-mediated formation of amidines

    Article • New Journal of Chemistry, January 2024, Royal Society of Chemistry

    Prof. Dr. Janez Kosmrlj

  8. Towards structurally versatile mesoionic N-heterocyclic olefin ligands and their coordination to palladium, gold, and boron hydride

    Article • Dalton Transactions, January 2024, Royal Society of Chemistry

    Prof. Dr. Janez Kosmrlj

  9. Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

    Article • Journal of Medicinal Chemistry, October 2023, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  10. Elucidating the reaction mechanism of a palladium-palladium dual catalytic process through kinetic studies of proposed elementary steps

    Article • Communications Chemistry, March 2023, Springer Science + Business Media

    Prof. Dr. Janez Kosmrlj

  11. Deuterated Drugs and Biomarkers in the COVID-19 Pandemic

    Article • ACS Omega, November 2022, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  12. Iridium Azocarboxamide Complexes: Variable Coordination Modes, C–H Activation, Transfer Hydrogenation Catalysis, and Mechanistic Insights

    Article • Organometallics, November 2021, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  13. A convenient approach to arenediazonium tosylates

    Article • Dyes and Pigments, January 2021, Elsevier

    Prof. Dr. Janez Kosmrlj

  14. Database Independent Automated Structure Elucidation of Organic Molecules Based on IR, 1H NMR, 13C NMR, and MS Data

    Article • Journal of Chemical Information and Modeling, December 2020, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  15. Designing Homogeneous Copper-Free Sonogashira Reaction through a Prism of Pd–Pd Transmetalation

    Article • Organic Letters, May 2020, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  16. Pyridine Wingtip in [Pd(Py-tzNHC)2]2+ Complex Is a Proton Shuttle in the Catalytic Hydroamination of Alkynes

    Article • Organic Letters, January 2020, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  17. Half-Sandwich Ir(III) and Os(II) Complexes of Pyridyl-Mesoionic Carbenes as Potential Anticancer Agents

    Article • Organometallics, October 2019, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  18. Arylation of Click Triazoles with Diaryliodonium Salts

    Article • The Journal of Organic Chemistry, September 2019, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  19. 1 H− 15 N HMBC NMR as a tool for rapid identification of isomeric azaindoles: The case of 5F‐MDMB‐P7AICA

    Article • Drug Testing and Analysis, February 2019, Wiley

    Prof. Dr. Janez Kosmrlj

  20. Polynuclear oxomolybdates(VI): Products of inadvertent oxidation of molybdenum(V) species

    Article • Inorganica Chimica Acta, February 2019, Elsevier

    Prof. Dr. Janez Kosmrlj

  21. Mechanism of copper-free Sonogashira reaction operates through palladium-palladium transmetallation

    Article • Nature Communications, November 2018, Springer Science + Business Media

    Prof. Dr. Janez Kosmrlj

  22. Versatile Coordination of Azocarboxamides: Redox‐Triggered Change of the Chelating Binding Pocket in Ruthenium Complexes

    Article • Chemistry - A European Journal, November 2018, Wiley

    Prof. Dr. Janez Kosmrlj

  23. Seasonal and spatial variations in the occurrence, mass loadings and removal of compounds of emerging concern in the Slovene aqueous environment and environmental risk assessment

    Article • Environmental Pollution, November 2018, Elsevier

    Prof. Dr. Janez Kosmrlj

  24. Synthesis of Bis(1,2,3-Triazole) Functionalized Quinoline-2,4-Diones

    Article • Molecules, September 2018, MDPI AG

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  25. The Value of In Vitro Binding as Predictor of In Vivo Results: A Case for [18F]FDDNP PET

    Article • Molecular Imaging and Biology, May 2018, Springer Science + Business Media

    Prof. Dr. Janez Kosmrlj

  26. Systematic Evaluation of 2-Arylazocarboxylates and 2-Arylazocarboxamides as Mitsunobu Reagents

    Article • The Journal of Organic Chemistry, March 2018, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  27. En Route to 2-(Cyclobuten-1-yl)-3-(trifluoromethyl)-1H-indole

    Article • The Journal of Organic Chemistry, February 2018, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  28. Synthesis and X-ray Structural Analysis of the Ruthenium(III) Complex Na[trans-RuCl4(DMSO) (PyrDiaz)], the Diazene Derivative of Antitumor NAMI-Pyr

    Article • December 2017, Slovenian Chemical Society

    Prof. Dr. Janez Kosmrlj

  29. 4-Hydroxyquinolin-2-one and Quinoline-2,4-dione based Compounds

    Article • Current Organic Chemistry, October 2017, Bentham Science Publishers

    Stanislav Kafka, Prof. Dr. Janez Kosmrlj

  30. Design, Syntheses, and in Vitro Evaluation of New Fluorine-18 Radiolabeled Tau-Labeling Molecular Probes

    Article • Journal of Medicinal Chemistry, October 2017, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  31. Synthesis and in vitro investigation of halogenated 1,3-bis(4-nitrophenyl)triazenide salts as antitubercular compounds

    Article • Chemical Biology & Drug Design, September 2017, Wiley

    Prof. Dr. Janez Kosmrlj

  32. Design, synthesis and antitubercular potency of 4-hydroxyquinolin-2(1 H )-ones

    Article • European Journal of Medicinal Chemistry, September 2017, Elsevier

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  33. Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis

    Article • European Journal of Medicinal Chemistry, February 2017, Elsevier

    Prof. Dr. Janez Kosmrlj

  34. Synthesis of 1,4-Benzodiazepine-2,5-diones by Base Promoted Ring Expansion of 3-Aminoquinoline-2,4-diones

    Article • The Journal of Organic Chemistry, November 2016, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  35. The Eighth Central European Conference “Chemistry towards Biology”: Snapshot

    Article • Molecules, October 2016, MDPI AG

    Professor Marc Diederich, Dr Atanas G. Atanasov, Prof. Pavel Matejka, Prof. Dr. Janez Kosmrlj

  36. Ruthenium Azocarboxamide Half-Sandwich Complexes: Influence of the Coordination Mode on the Electronic Structure and Activity in Base-Free Transfer Hydrogenation Catalysis

    Article • Organometallics, August 2016, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  37. The “Fully Catalytic System” in Mitsunobu Reaction Has Not Been Realized Yet

    Article • Organic Letters, August 2016, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  38. Amide Assisted Regioselective Hydrolysis and Transesterification of Dimethyl 3-Benzamidophthalates

    Article • The Journal of Organic Chemistry, June 2016, American Chemical Society (ACS)

    Professor Franc Perdih, Prof. Dr. Janez Kosmrlj

  39. A mesoionic bis(Py-tzNHC) palladium(ii) complex catalyses “green” Sonogashira reaction through an unprecedented mechanism

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Prof. Dr. Janez Kosmrlj

  40. Discovery of ‘click’ 1,2,3-triazolium salts as potential anticancer drugs

    Article • Radiology and Oncology, January 2016, De Gruyter

    Prof. Dr. Janez Kosmrlj

  41. Advances and mechanistic insight on the catalytic Mitsunobu reaction using recyclable azo reagents

    Article • Chemical Science, January 2016, Royal Society of Chemistry

    Prof. Dr. Janez Kosmrlj

  42. RuII, IrIII and OsII mesoionic carbene complexes: efficient catalysts for transfer hydrogenation of selected functionalities

    Article • Dalton Transactions, January 2016, Royal Society of Chemistry

    Prof. Dr. Janez Kosmrlj

  43. The 1,3-diaryltriazenido(p-cymene)ruthenium(II) complexes with a high in vitro anticancer activity

    Article • Journal of Inorganic Biochemistry, December 2015, Elsevier

    Prof. Dr. Janez Kosmrlj

  44. RuII, OsII, and IrIIIComplexes with Chelating Pyridyl-Mesoionic Carbene Ligands: Structural Characterization and Applications in Transfer Hydrogenation Catalysis

    Article • Chemistry - A European Journal, March 2015, Wiley

    Prof. Dr. Janez Kosmrlj

  45. Completely Stereocontrolled Aldol Reaction of Chiral β-Amino Acids

    Article • Organic Letters, January 2015, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  46. Catalytic oxygenation of sp3 “C–H” bonds with Ir(iii) complexes of chelating triazoles and mesoionic carbenes

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Prof. Dr. Janez Kosmrlj

  47. Combining [Arene-Ru] with Azocarboxamide to Generate a Complex with Cytotoxic Properties

    Article • Chemistry - A European Journal, November 2014, Wiley

    Prof. Dr. Janez Kosmrlj

  48. Synthesis and NMR Analysis of 1,4-Disubstituted 1,2,3-Triazoles Tethered to Pyridine, Pyrimidine, and Pyrazine Rings

    Article • European Journal of Organic Chemistry, October 2014, Wiley

    Prof. Dr. Janez Kosmrlj

  49. Exploring the Scope of Pyridyl- and Picolyl-Functionalized 1,2,3-Triazol-5-ylidenes in Bidentate Coordination to Ruthenium(II) Cymene Chloride Complexes

    Article • Organometallics, May 2014, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  50. Anti-mycobacterial activity of 1,3-diaryltriazenes

    Article • European Journal of Medicinal Chemistry, April 2014, Elsevier

    Prof. Dr. Janez Kosmrlj

  51. Biological evaluation of diazene derivatives as anti-tubercular compounds

    Article • European Journal of Medicinal Chemistry, March 2014, Elsevier

    Prof. Dr. Janez Kosmrlj

  52. Fischer indolisation of N-(α-ketoacyl)anthranilic acids.

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Stanislav Kafka, Prof. Dr. Janez Kosmrlj

  53. Oxidative ring opening of 3-hydroxyquinoline-2,4(1H,3H)-diones into N-(α-ketoacyl)anthranilic acids

    Article • Tetrahedron, December 2013, Elsevier

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  54. A Selective Approach to Pyridine Appended 1,2,3-Triazolium Salts

    Article • Organic Letters, September 2013, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  55. Platinum-Mediated Dinitrogen Liberation from 2-Picolyl Azide through a Putative Pt═N Double Bond Containing Intermediate

    Article • Inorganic Chemistry, March 2013, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  56. 4-Hydroxy-1-methyl-3-phenylquinolin-2(1H)-one

    Article • Acta Crystallographica Section E Structure Reports Online, January 2013, International Union of Crystallography

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  57. 3-Ethyl-3-hydroxy-8-methoxyquinoline-2,4(1H,3H)-dione monohydrate

    Article • Acta Crystallographica Section E Structure Reports Online, October 2012, International Union of Crystallography

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  58. 3-Ethyl-4-hydroxy-8-methoxyquinolin-2(1H)-one

    Article • Acta Crystallographica Section E Structure Reports Online, October 2012, International Union of Crystallography

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  59. Concise and highly efficient approach to three key pyrimidine precursors for rosuvastatin synthesis

    Article • Tetrahedron, March 2012, Elsevier

    Prof. Dr. Janez Kosmrlj

  60. Click Triazoles

    Article • January 2012, Springer Science + Business Media

    Prof. Dr. Janez Kosmrlj

  61. New series of isoniazid hydrazones linked with electron-withdrawing substituents

    Article • European Journal of Medicinal Chemistry, December 2011, Elsevier

    Prof. Dr. Janez Kosmrlj

  62. 2-Hydroxy-2-methyl-1-phenylindolin-3-one

    Article • Acta Crystallographica Section E Structure Reports Online, November 2011, International Union of Crystallography

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  63. Conformational fluxionality in a palladium(II) complex of flexible click chelator 4-phenyl-1-(2-picolyl)-1,2,3-triazole: A dynamic NMR and DFT study

    Article • Polyhedron, August 2011, Elsevier

    Prof. Dr. Janez Kosmrlj

  64. Copper(I)-Catalyzed [ 3+ 2] Cycloaddition of 3-Azidoquinoline-2,4(1H,3H)-diones with Terminal Alkynes

    Article • Molecules, May 2011, MDPI AG

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  65. Synthesis and Characterization of Platinum(II) Complexes with a Diazenecarboxamide-Appended Picolyl-Triazole Ligand

    Article • European Journal of Inorganic Chemistry, March 2011, Wiley

    Prof. Dr. Janez Kosmrlj

  66. 1-(2-Picolyl)-substituted 1,2,3-triazole as novel chelating ligand for the preparation of ruthenium complexes with potential anticancer activity

    Article • Dalton Transactions, January 2011, Royal Society of Chemistry

    Dr Ioannis Bratsos, Iztok Turel, Prof. Dr. Janez Kosmrlj

  67. Preparation of diazenecarboxamide–carboplatin conjugates by click chemistry

    Article • Inorganica Chimica Acta, November 2010, Elsevier

    Prof. Dr. Janez Kosmrlj

  68. Pyridyl Conjugated 1,2,3-Triazole is a Versatile Coordination Ability Ligand Enabling Supramolecular Associations

    Article • Crystal Growth & Design, October 2010, American Chemical Society (ACS)

    Iztok Turel, Prof. Dr. Janez Kosmrlj

  69. Lactone Pathway to Statins Utilizing the Wittig Reaction. The Synthesis of Rosuvastatin

    Article • The Journal of Organic Chemistry, October 2010, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  70. 3-Ethyl-8-methoxy-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)quinolin-2(1H)-one

    Article • Acta Crystallographica Section E Structure Reports Online, May 2010, International Union of Crystallography

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  71. Click-Triazole N2 Coordination to Transition-Metal Ions Is Assisted by a Pendant Pyridine Substituent

    Article • Inorganic Chemistry, May 2010, American Chemical Society (ACS)

    Iztok Turel, Prof. Dr. Janez Kosmrlj

  72. N-(Propargyl)diazenecarboxamides for ‘click’ conjugation and their 1,3-dipolar cycloadditions with azidoalkylamines in the presence of Cu(II)

    Article • Tetrahedron, April 2010, Elsevier

    Prof. Dr. Janez Kosmrlj

  73. Selective formation of glycosidic linkages of N-unsubstituted 4-hydroxyquinolin-2-(1H)-ones

    Article • Carbohydrate Research, April 2010, Elsevier

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  74. Diazenes as Powerful and Versatile Tools in Organic Synthesis

    Article • Synlett, July 2009, Thieme Publishing Group

    Prof. Dr. Janez Kosmrlj

  75. The First Convenient Entry to δ-Formyl-δ-valerolactone Precursor for the Synthesis of Statins via Lactonized Side Chain

    Article • Synlett, March 2009, Thieme Publishing Group

    Prof. Dr. Janez Kosmrlj

  76. The first entry to pyrrolo[2,3-c]quinoline-2,4(3aH,5H)-diones

    Article • Tetrahedron, May 2008, Elsevier

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  77. Rearrangement of furo[2,3-c]quinoline-2,4(3aH,5H)-diones to furo[3,4-c]quinoline-3,4(1H,5H)-diones

    Article • Tetrahedron Letters, January 2008, Elsevier

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  78. Selective cytotoxicity of diazenecarboxamides towards human leukemic cell lines

    Article • Toxicology in Vitro, December 2007, Elsevier

    Prof. Dr. Janez Kosmrlj

  79. Formation and structure elucidation of two novel spiro[2H-indol]-3(1H)-ones

    Article • Magnetic Resonance in Chemistry, January 2007, Wiley

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  80. X-Ray crystallographic, NMR and antimicrobial activity studies of magnesium complexes of fluoroquinolones – racemic ofloxacin and its S-form, levofloxacin

    Article • Journal of Inorganic Biochemistry, November 2006, Elsevier

    Iztok Turel, Prof. Dr. Janez Kosmrlj

  81. Diazene JK-279 induces apoptosis-like cell death in human cervical carcinoma cells

    Article • Toxicology in Vitro, March 2006, Elsevier

    Prof. Dr. Janez Kosmrlj

  82. Novel Tandem Hydration/Cyclodehydration of α-Thiocyanatoketones to 2-Oxo-3-thiazolines. Application to Thiazolo[5,4-c]quinoline-2,4(3aH,5H)-dione Synthesis

    Article • The Journal of Organic Chemistry, August 2004, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  83. Synthesis of 5H-pyridazino[4,5-b]indoles and their benzofurane analogues utilizing an intramolecular Heck-type reaction

    Article • Tetrahedron, March 2004, Elsevier

    Prof. Dr. Janez Kosmrlj

  84. Development of potential anti-cancer agents: Diazenes and derivatives

    Article • Drug Development Research, January 2004, Wiley

    Prof. Dr. Janez Kosmrlj

  85. Pt(II) complexes with N-(3-pyridyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide and their reactions with glutathione

    Article • Journal of Inorganic Biochemistry, June 2003, Elsevier

    Prof. Dr. Janez Kosmrlj

  86. Evaluation of the Enantiomeric Resolution of 7,8-Dihydroxy-7,8-dihydrobenzo[a]- pyrene and Its 6-Fluoro and 6-Bromo Derivatives on Polysaccharide-Derived Stationary Phases

    Article • The Journal of Organic Chemistry, April 2003, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  87. Unfunctionalized, α-Epimerizable Nonracemic Ketones and Aldehydes Can Be Accessed by Crystallization-Induced Dynamic Resolution of Imines†

    Article • Journal of the American Chemical Society, March 2003, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  88. Diazenecarboxamide UP-91, a Potential Anticancer Agent, Acts by Reducing Cellular Glutathione Content

    Article • Pharmacology & Toxicology, November 2002, Wiley

    Prof. Dr. Janez Kosmrlj

  89. Variable-Temperature Nuclear Magnetic Resonance Spectroscopy Allows Direct Observation of Carboxylate Shift in Zinc Carboxylate Complexes

    Article • Journal of the American Chemical Society, April 2002, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj

  90. Cytotoxic Effects of Diazenes on Tumor Cells in vitro

    Article • Chemotherapy, January 2002, Karger Publishers

    Prof. Dr. Janez Kosmrlj

  91. Novel Ring Contraction of 3-Hydroxy-2,4(1H,3H)-quinolinediones in Aqueous Alkali. The First Convenient Route to 2-Hydroxyindoxyls

    Article • The Journal of Organic Chemistry, September 2001, American Chemical Society (ACS)

    Prof. Dr. Janez Kosmrlj, Stanislav Kafka

  92. Suzuki reactions on chloropyridazinones: an easy approach towards arylated 3(2 H )-pyridazinones

    Article • Tetrahedron, February 2001, Elsevier

    Prof. Dr. Janez Kosmrlj

  93. Synthesis of Novel 3-Acyloxy-1,3-dihydro-2H-indol-2-ones and Isomeric 4-Acyl-1,4-dihydro-3,1-benzoxazin-2-ones: Double Rearrangement of 3-Hydroxyquinoline-2,4(1H,3H)-diones

    Article • Tetrahedron, March 2000, Elsevier

    Prof. Dr. Janez Kosmrlj

  94. NMR Investigation of the Copper(II)‐Ciprofloxacin System

    Article • Metal-Based Drugs, December 1998, Wiley

    Iztok Turel, Prof. Dr. Janez Kosmrlj