All Stories

  1. Rational Design of an Antimicrobial Peptide Based on Structural Insight into the Interaction of Pseudomonas aeruginosa Initiation Factor 1 with Its Cognate 30S Ribosomal Subunit

    Article • ACS Infectious Diseases, October 2021, American Chemical Society (ACS)

    Dr James M Bullard

  2. Two Forms of Tyrosyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Discovery of Inhibitory Compounds

    Article • SLAS DISCOVERY, October 2020, Elsevier

    Dr James M Bullard

  3. Identification and Characterization of Chemical Compounds that Inhibit Leucyl-tRNA Synthetase from Pseudomonas aeruginosa

    Article • Current Drug Discovery Technologies, April 2020, Bentham Science Publishers

    Dr James M Bullard

  4. 1H, 13C and 15N resonance assignments of translation initiation factor 3 from Pseudomonas aeruginosa

    Article • Biomolecular NMR Assignments, January 2020, Springer Science + Business Media

    Dr James M Bullard

  5. Glutaminyl‐tRNA Synthetase from Pseudomonas aeruginosa : Characterization, Structure, and Development as a Screening Platform

    Article • Protein Science, December 2019, Wiley

    Dr James M Bullard

  6. Lysyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Identification of Inhibitory Compounds

    Article • SLAS DISCOVERY, September 2019, SAGE Publications

    Dr James M Bullard

  7. Characterization and structure determination of prolyl‐tRNA synthetase from Pseudomonas aeruginosa and development as a screening platform

    Article • Protein Science, February 2019, Wiley

    Dr James M Bullard

  8. Design, synthesis and microbiological evaluation of novel compounds as potential Staphylococcus aureus phenylalanine tRNA synthetase inhibitors

    Article • Egyptian Journal of Chemistry, July 2018, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr James M Bullard

  9. Discovery and Characterization of Chemical Compounds That Inhibit the Function of Aspartyl-tRNA Synthetase from Pseudomonas aeruginosa

    Article • SLAS DISCOVERY, November 2017, SAGE Publications

    Dr James M Bullard

  10. Identification and Characterization of a Chemical Compound that Inhibits Methionyl-tRNA Synthetase from Pseudomonas aeruginosa

    Article • Current Drug Discovery Technologies, August 2017, Bentham Science Publishers

    Dr James M Bullard

  11. Identification of Chemical Compounds That Inhibit the Function of Histidyl-tRNA Synthetase from Pseudomonas aeruginosa

    Article • SLAS DISCOVERY, July 2017, SAGE Publications

    Dr James M Bullard

  12. Identification of Chemical Compounds That Inhibit Protein Synthesis in Pseudomonas aeruginosa

    Article • SLAS DISCOVERY, November 2016, SAGE Publications

    Dr James M Bullard

  13. Solution structure of protein synthesis initiation factor 1 from Pseudomonas aeruginosa

    Article • Protein Science, September 2016, Wiley

    Dr James M Bullard

  14. NMR structure of IF1 from Pseudomonas aeruginosa

    Article • September 2016, Protein Data Bank, Rutgers University

    Dr James M Bullard

  15. Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa

    Article • Antimicrobial Agents and Chemotherapy, May 2016, ASM Journals

    Dr James M Bullard

  16. 1H, 13C and 15N resonance assignments and secondary structure analysis of translation initiation factor 1 from Pseudomonas aeruginosa

    Article • Biomolecular NMR Assignments, March 2016, Springer Science + Business Media

    Dr James M Bullard

  17. Identification of Chemical Compounds That Inhibit the Function of Glutamyl-tRNA Synthetase from Pseudomonas aeruginosa

    Article • SLAS DISCOVERY, June 2015, SAGE Publications

    Dr James M Bullard

  18. High Throughput Screen Identifies Natural Product Inhibitor of Phenylalanyl-tRNA Synthetase from Pseudomonas aeruginosa and Streptococcus pneumoniae

    Article • Current Drug Discovery Technologies, May 2015, Bentham Science Publishers

    Dr James M Bullard

  19. Long-Range PCR Amplification of DNA by DNA Polymerase III Holoenzyme fromThermus thermophilus

    Article • Enzyme Research, January 2015, Hindawi Publishing Corporation

    Dr James M Bullard

  20. Chemical Cleavage as a Probe of Ribosomal Structure

    Article • April 2014, ASM Journals

    Dr James M Bullard

  21. Two Homologous EF-G Proteins from Pseudomonas aeruginosa Exhibit Distinct Functions

    Article • PLOS One, November 2013, PLOS

    Dr James M Bullard

  22. Cloning and Characterization of EF-Tu and EF-Ts fromPseudomonas aeruginosa

    Article • BioMed Research International, January 2013, Hindawi Publishing Corporation

    Dr James M Bullard

  23. Development of 4H-pyridopyrimidines: a class of selective bacterial protein synthesis inhibitors

    Article • Organic and Medicinal Chemistry Letters, January 2012, Springer Science + Business Media

    Dr James M Bullard

  24. Discovery and Analysis of 4H-Pyridopyrimidines, a Class of Selective Bacterial Protein Synthesis Inhibitors

    Article • Antimicrobial Agents and Chemotherapy, November 2010, ASM Journals

    Dr James M Bullard

  25. Spectrum of activity and mode of action of REP3123, a new antibiotic to treat Clostridium difficile infections

    Article • Journal of Antimicrobial Chemotherapy, March 2009, Oxford University Press (OUP)

    Dr James M Bullard

  26. DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP and Mn

    Article • January 2009, Protein Data Bank, Rutgers University

    Dr James M Bullard

  27. DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP, Mg and Zn

    Article • January 2009, Protein Data Bank, Rutgers University

    Dr James M Bullard

  28. Structure of PolC reveals unique DNA binding and fidelity determinants

    Article • Proceedings of the National Academy of Sciences, December 2008, Proceedings of the National Academy of Sciences

    Dr James M Bullard

  29. Inhibition of Methionyl-tRNA Synthetase by REP8839 and Effects of Resistance Mutations on Enzyme Activity

    Article • Antimicrobial Agents and Chemotherapy, November 2008, ASM Journals

    Dr James M Bullard

  30. Discovery and Characterization of the Cryptic Ψ Subunit of the Pseudomonad DNA Replicase

    Article • Journal of Biological Chemistry, October 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr James M Bullard

  31. Reconstitution of a Minimal DNA Replicase from Pseudomonas aeruginosa and Stimulation by Non-cognate Auxiliary Factors

    Article • Journal of Biological Chemistry, December 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr James M Bullard

  32. A Three-domain Structure for the   Subunit of the DNA Polymerase III Holoenzyme   Domain III Binds  ' and Assembles into the DnaX Complex

    Article • Journal of Biological Chemistry, April 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr James M Bullard

  33. DNA Polymerase III Holoenzyme from Thermus thermophilus Identification, Expression, Purification of Components, and Use to Reconstitute a Processive Replicase

    Article • Journal of Biological Chemistry, January 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr James M Bullard

  34. Interaction of Mitochondrial Elongation Factor Tu with Aminoacyl-tRNA and Elongation Factor Ts

    Article • Journal of Biological Chemistry, May 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr James M Bullard

  35. Expression and characterization of the human mitochondrial leucyl-tRNA synthetase

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, February 2000, Elsevier

    Dr James M Bullard

  36. Effects of domain exchanges between Escherichia coli and mammalian mitochondrial EF-Tu on interactions with guanine nucleotides, aminoacyl-tRNA and ribosomes

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, July 1999, Elsevier

    Dr James M Bullard

  37. Expression and characterization of a human mitochondrial phenylalanyl-tRNA synthetase 1 1Edited by D. E. Draper

    Article • Journal of Molecular Biology, May 1999, Elsevier

    Dr James M Bullard

  38. Regions of 16S Ribosomal RNA Proximal to Transfer RNA Bound at the P-Site of Escherichia coli Ribosomes †

    Article • Biochemistry, February 1998, American Chemical Society (ACS)

    Dr James M Bullard

  39. Cleavage of 16S rRNA within the Ribosome by mRNA Modified in the A-Site Codon with Phenanthroline-Cu(II) †

    Article • Biochemistry, July 1997, American Chemical Society (ACS)

    Dr James M Bullard

  40. Mechanistic studies of the translational elongation cycle in mammalian mitochondria

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, May 1997, Elsevier

    Dr James M Bullard

  41. Identification of ribosome–ligand interactions using cleavage reagents

    Article • Biochemistry and Cell Biology, December 1995, Canadian Science Publishing

    Dr James M Bullard

  42. Regions of 23 S Ribosomal RNA Proximal to Transfer RNA bound at the P and E Sites

    Article • Journal of Molecular Biology, October 1995, Elsevier

    Dr James M Bullard