Contact

All Stories

  1. Bacillus thuringiensis Cry1AbMod toxin counters tolerance associated with low cadherin expression but not that associated with low alkaline phosphatase expression in Manduca sexta

    Article • Peptides, June 2015, Elsevier

    Dr Isabel Gomez

  2. Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12

    Article • Insect Biochemistry and Molecular Biology, April 2015, Elsevier

    Dr Isabel Gomez

  3. Identification and Characterization of Receptors for Insecticidal Toxins from Bacillus thuringiensis

    Article • January 2015, Springer Science + Business Media

    Dr Isabel Gomez

  4. Bacillus thuringiensis Cry1A toxins are versatile proteins with multiple modes of action: two distinct pre-pores are involved in toxicity

    Article • Biochemical Journal, April 2014, Portland Press Ltd.

    Dr Isabel Gomez

  5. Differential Role of Manduca sexta Aminopeptidase-N and Alkaline Phosphatase in the Mode of Action of Cry1Aa, Cry1Ab, and Cry1Ac Toxins from Bacillus thuringiensis

    Article • Applied and Environmental Microbiology, May 2013, ASM Journals

    Dr Isabel Gomez

  6. Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non-toxic to Manduca sexta larvae.

    Article • Journal of Biological Chemistry, March 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  7. A Tenebrio molitor GPI-anchored alkaline phosphatase is involved in binding of Bacillus thuringiensis Cry3Aa to brush border membrane vesicles

    Article • Peptides, March 2013, Elsevier

    Dr Isabel Gomez

  8. Oligomerization of Cry11Aa from Bacillus thuringiensis Has an Important Role in Toxicity against Aedes aegypti

    Article • Applied and Environmental Microbiology, February 2013, ASM Journals

    Dr Isabel Gomez

  9. Domains II and III of Bacillus thuringiensis Cry1Ab toxin remain exposed to the solvent after insertion of part of domain I into the membrane.: FIGURE S1.

    Article • Journal of Biological Chemistry, October 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  10. 125. Cadherin Binding Is Not a Limiting Step for Bacillus thuringiensis subs. israelensis Cry4Ba Toxicity to Aedes aegypti Larvae

    Article • Toxicon, August 2012, Elsevier

    Dr Isabel Gomez

  11. Cadherin binding is not a limiting step for Bacillus thuringiensis subsp. israelensis Cry4Ba toxicity to Aedes aegypti larvae

    Article • Biochemical Journal, May 2012, Portland Press Ltd.

    Dr Isabel Gomez

  12. Evolution ofBacillus thuringiensisCry toxins insecticidal activity

    Article • Microbial Biotechnology, March 2012, Wiley

    Dr Isabel Gomez

  13. Role of GPI-Anchored Membrane Receptors in the Mode of Action of Bacillus thuringiensis Cry Toxins

    Article • February 2012, IntechOpen

    Dr Isabel Gomez

  14. Domains II and III of Bacillus thuringiensis Cry1Ab Toxin Remain Exposed to the Solvent after Insertion of Part of Domain I into the Membrane

    Article • Journal of Biological Chemistry, April 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  15. Role of Alkaline Phosphatase from Manduca sexta in the Mechanism of Action of Bacillus thuringiensis Cry1Ab Toxin

    Article • Journal of Biological Chemistry, February 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  16. Oligomerization of Cry11Aa from Bacillus thuringiensis Has an Important Role in Toxicity against Aedes aegypti

    Article • Applied and Environmental Microbiology, October 2009, ASM Journals

    Dr Isabel Gomez

  17. Domain II Loop 3 of Bacillus thuringiensis Cry1Ab Toxin Is Involved in a "Ping Pong" Binding Mechanism with Manduca sexta Aminopeptidase-N and Cadherin Receptors

    Article • Journal of Biological Chemistry, October 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  18. Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation

    Article • Peptides, March 2009, Elsevier

    Dr Isabel Gomez

  19. Employing phage display to study the mode of action of Bacillus thuringiensis Cry toxins

    Article • Peptides, February 2008, Elsevier

    Dr Isabel Gomez

  20. The pre-pore from Bacillus thuringiensis Cry1Ab toxin is necessary to induce insect death in Manduca sexta

    Article • Peptides, February 2008, Elsevier

    Dr Isabel Gomez

  21. Bacillus thuringiensis Cry1Ab Mutants Affecting Oligomer Formation Are Non-toxic to Manduca sexta Larvae

    Article • Journal of Biological Chemistry, May 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  22. Role of receptor interaction in the mode of action of insecticidal Cry and Cyt toxins produced by Bacillus thuringiensis

    Article • Peptides, January 2007, Elsevier

    Dr Isabel Gomez

  23. Specific Epitopes of Domains II and III ofBacillus thuringiensisCry1Ab Toxin Involved in the Sequential Interaction with Cadherin and Aminopeptidase-N Receptors inManduca sexta

    Article • Journal of Biological Chemistry, September 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  24. Structural Changes of the Cry1Ac Oligomeric Pre-Pore fromBacillus thuringiensisInduced byN-Acetylgalactosamine Facilitates Toxin Membrane Insertion†

    Article • Biochemistry, August 2006, American Chemical Society (ACS)

    Dr Isabel Gomez

  25. Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage

    Article • Journal of Invertebrate Pathology, May 2006, Elsevier

    Dr Isabel Gomez

  26. Role of Tryptophan Residues in Toxicity of Cry1Ab Toxin from Bacillus thuringiensis

    Article • Applied and Environmental Microbiology, January 2006, ASM Journals

    Dr Isabel Gomez

  27. Oligomerization triggers binding of a Bacillus thuringiensis Cry1Ab pore-forming toxin to aminopeptidase N receptor leading to insertion into membrane microdomains

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, November 2004, Elsevier

    Dr Isabel Gomez

  28. Tryptophan Spectroscopy Studies and Black Lipid Bilayer Analysis Indicate that the Oligomeric Structure of Cry1Ab Toxin from Bacillus thuringiensis Is the Membrane-Insertion Intermediate †

    Article • Biochemistry, January 2004, American Chemical Society (ACS)

    Dr Isabel Gomez

  29. Molecular Basis for Bacillus thuringiensis Cry1Ab Toxin Specificity:  Two Structural Determinants in the Manduca sexta Bt-R 1 Receptor Interact with Loops α-8 and 2 in Domain II of Cy1Ab Toxin †

    Article • Biochemistry, September 2003, American Chemical Society (ACS)

    Dr Isabel Gomez

  30. Functional studies of helix alpha-5 region from Bacillus thuringiensis Cry1Ab delta-endotoxin

    Article • January 2003, Taylor & Francis

    Dr Isabel Gomez

  31. Hydropathic Complementarity Determines Interaction of Epitope 869HITDTNNK876 in Manduca sexta Bt-R1 Receptor with Loop 2 of Domain II of Bacillus thuringiensis Cry1A Toxins

    Article • Journal of Biological Chemistry, June 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Isabel Gomez

  32. Pore formation activity of Cry1Ab toxin from Bacillus thuringiensis in an improved membrane vesicle preparation from Manduca sexta midgut cell microvilli

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, May 2002, Elsevier

    Dr Isabel Gomez

  33. Cadherin-like receptor binding facilitates proteolytic cleavage of helix α-1 in domain I and oligomer pre-pore formation ofBacillus thuringiensisCry1Ab toxin

    Article • FEBS Letters, February 2002, Wiley

    Dr Isabel Gomez

  34. Evidence for intermolecular interaction as a necessary step for pore-formation activity and toxicity of Bacillus thuringiensis Cry1Ab toxin

    Article • FEMS Microbiology Letters, October 2000, Oxford University Press (OUP)

    Dr Isabel Gomez