All Stories

  1. Understanding the Impact of Hypoxia on Pulmonary Artery Endothelial Cells in Chronic Thromboembolic Pulmonary Hypertension Patients
  2. Precise Dynamic Control of Tissue Oxygenation during Brain Slice Electrophysiology
  3. Open-Source Device to Apply Controlled Positive or Negative Airway Pressure for Vocal Training
  4. Optimized Open-Source Setting for Subjecting Rodents to Chronic Normobaric Hypoxia in Facilities with Minimal Nitrogen Supply
  5. Normalization of Oxygen Levels Induces a Metabolic Reprogramming in Livers Exposed to Intermittent Hypoxia Mimicking Obstructive Sleep Apnea
  6. Low-Cost, Open-Source Device for Simultaneously Subjecting Rodents to Different Circadian Cycles of Light, Food, and Temperature
  7. Lung Micrometastases Display ECM Depletion and Softening While Macrometastases Are 30-Fold Stiffer and Enriched in Fibronectin
  8. Multi-Step Extracellular Matrix Remodelling and Stiffening in the Development of Idiopathic Pulmonary Fibrosis
  9. Experimental Models to Study End-Organ Morbidity in Sleep Apnea: Lessons Learned and Future Directions
  10. Lung Extracellular Matrix Hydrogels-Derived Vesicles Contribute to Epithelial Lung Repair
  11. Characterization of 3D Printed Metal-PLA Composite Scaffolds for Biomedical Applications
  12. hLMSC Secretome Affects Macrophage Activity Differentially Depending on Lung-Mimetic Environments
  13. Aging Impairs Reverse Remodeling and Recovery of Ventricular Function after Isoproterenol-Induced Cardiomyopathy
  14. Baseline Stiffness Modulates the Non-Linear Response to Stretch of the Extracellular Matrix in Pulmonary Fibrosis
  15. Human experimental models: seeking to enhance multiscale research in sleep apnoea
  16. Heterogeneity of Melanoma Cell Responses to Sleep Apnea-Derived Plasma Exosomes and to Intermittent Hypoxia
  17. Image-Based Method to Quantify Decellularization of Tissue Sections
  18. Oxygen Biosensors and Control in 3D Physiomimetic Experimental Models
  19. Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells
  20. Experimental Setting for Applying Mechanical Stimuli to Study the Endothelial Response of Ex Vivo Vessels under Realistic Pathophysiological Environments
  21. Metabolic dysfunction in OSA: Is there something new under the sun?
  22. Open access spreadsheet application for learning spontaneous breathing mechanics and mechanical ventilation
  23. The effect of chronic intermittent hypoxia in cardiovascular gene expression is modulated by age in a mice model of sleep apnea
  24. Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma
  25. Impact of sleep fragmentation, heart failure, and their combination, on the gut microbiome
  26. Intrahepatic Expression of Fatty Acid Translocase CD36 Is Increased in Obstructive Sleep Apnea
  27. The conventional isoproterenol-induced heart failure model does not consistently mimic the diaphragmatic dysfunction observed in patients
  28. Understanding the pathophysiological mechanisms of cardiometabolic complications in obstructive sleep apnoea: towards personalised treatment approaches
  29. ERS International Congress, Madrid, 2019: highlights from the Sleep and Clinical Physiology Assembly
  30. Biophysically Preconditioning Mesenchymal Stem Cells Improves Treatment of Ventilator-Induced Lung Injury
  31. Lung cancer aggressiveness in an intermittent hypoxia murine model of postmenopausal sleep apnea
  32. Obesity, sleep apnea, and cancer
  33. Chronic Sleep Fragmentation Mimicking Sleep Apnea Does Not Worsen Left-Ventricular Function in Healthy and Heart Failure Mice
  34. Obstructive sleep apnea intensifies stroke severity following middle cerebral artery occlusion
  35. Cancer and Sleep Apnea: Cutaneous Melanoma as a Case Study
  36. Differential effect of intermittent hypoxia and sleep fragmentation on PD-1/PD-L1 upregulation
  37. Effects of Sustained and Intermittent Hypoxia on Human Lung Cancer Cells
  38. Late Breaking Abstract - Fetal blood hypoxia/reoxygenation swings are reduced by placental oxygen transfer in a model ovine pregnancy with sleep apnea
  39. Lung extracellular matrix hydrogel for 3D bioprinting of lung mesenchymal stem cells
  40. Early Career Members at the Lung Science Conference and the Sleep and Breathing Conference 2019
  41. Placental oxygen transfer reduces hypoxia-reoxygenation swings in fetal blood in a sheep model of gestational sleep apnea
  42. Biomechanical Response of Lung Epithelial Cells to Iron Oxide and Titanium Dioxide Nanoparticles
  43. Aortic remodelling induced by obstructive apneas is normalized with mesenchymal stem cells infusion
  44. Highlights from the 2018 European Respiratory Society International Congress: sleep and clinical physiology
  45. Effect of age on the cardiovascular remodelling induced by chronic intermittent hypoxia as a murine model of sleep apnoea
  46. Why ERS Early Career Members should attend the International Congress 2019 in Madrid
  47. Preview of Sleep and Breathing Conference 2019 and report on Early Career Member international collaboration
  48. Differential Oxygenation in Tumor Microenvironment Modulates Macrophage and Cancer Cell Crosstalk: Novel Experimental Setting and Proof of Concept
  49. Soluble PD-L1 is a potential biomarker of cutaneous melanoma aggressiveness and metastasis in obstructive sleep apnoea patients
  50. Age‐dependent hypoxia‐induced PD‐L1 upregulation in patients with obstructive sleep apnoea
  51. Escherichia coli lipopolysaccharide induces alveolar epithelial cell stiffening
  52. Gas Partial Pressure in Cultured Cells: Patho-Physiological Importance and Methodological Approaches
  53. Sleep-Disordered Breathing Is Independently Associated With Increased Aggressiveness of Cutaneous Melanoma
  54. Intermittent Hypoxia Severity in Animal Models of Sleep Apnea
  55. Passive Stiffness of Left Ventricular Myocardial Tissue Is Reduced by Ovariectomy in a Post-menopause Mouse Model
  56. Aging Reduces Intermittent Hypoxia–induced Lung Carcinoma Growth in a Mouse Model of Sleep Apnea
  57. Overnight Change in Urinary Prostacyclin and Thromboxane in Obstructive Sleep Apnea
  58. Intermittent hypoxia and cancer: Undesirable bed partners?
  59. Clinical physiology and sleep: highlights from the European Respiratory Society Congress 2018 presented by early career members
  60. Intermittent Hypoxia Mimicking Sleep Apnea Increases Passive Stiffness of Myocardial Extracellular Matrix. A Multiscale Study
  61. Early Career Members at the ERS Lung Science Conference: cell-matrix interactions in lung disease and regeneration
  62. Zooming in on the ERS fellowships and the International Congress
  63. Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea
  64. Exosomal Cargo Properties, Endothelial Function and Treatment of Obesity Hypoventilation Syndrome: A Proof of Concept Study
  65. Intermittent Hypoxia Is Associated With High Hypoxia Inducible Factor-1α but Not High Vascular Endothelial Growth Factor Cell Expression in Tumors of Cutaneous Melanoma Patients
  66. Biomarkers of carcinogenesis and tumour growth in patients with cutaneous melanoma and obstructive sleep apnoea
  67. Alzheimer’s Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea
  68. Bioengineered Lungs: A Challenge and An Opportunity
  69. Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia
  70. Early Career Members at the ERS International Congress 2017: highlights from the Assemblies
  71. A prospective multicenter cohort study of cutaneous melanoma
  72. Early Career Members at the ERS LSC 2017: mechanistic overlap between chronic lung injury and cancer
  73. Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules
  74. Clinical physiology and sleep: insights from the European Respiratory Society Congress 2017
  75. Frequency and magnitude of intermittent hypoxia modulate endothelial wound healing in a cell culture model of sleep apnea
  76. Obstructive Sleep Apnea and Atherosclerosis: Both the Gut Microbiome and Hypercapnia Matter
  77. Hypoxia-induced PD-L1/PD-1 crosstalk impairs T-cell function in sleep apnoea
  78. Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice
  79. Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea
  80. Apnea del sueño y agresividad tumoral
  81. Visceral White Adipose Tissue after Chronic Intermittent and Sustained Hypoxia in Mice
  82. Sleep apnoea, insulin resistance and diabetes: the first step is in the fat
  83. Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea
  84. Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36
  85. Chronic intermittent hypoxia mimicking sleep apnoea increases spontaneous tumorigenesis in mice
  86. Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery
  87. Altered CD8+ T-Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep Apnea
  88. Early effects of continuous positive airway pressure in a rodent model of allergic rhinitis
  89. Tumor Cell Malignant Properties Are Enhanced by Circulating Exosomes in Sleep Apnea
  90. Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice
  91. Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice
  92. A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea
  93. Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation
  94. Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung
  95. Does obstructive sleep apnea confer risk to induce or enhance tumor malignancy?
  96. Intermittent Hypoxia-Induced Cardiovascular Remodeling Is Reversed by Normoxia in a Mouse Model of Sleep Apnea
  97. Obstructive sleep apnea and Fuhrman grade in patients with clear cell renal cell carcinoma treated surgically
  98. Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice
  99. Microarray-based analysis of plasma cirDNA epigenetic modification profiling in xenografted mice exposed to intermittent hypoxia
  100. Relación entre apnea del sueño y cáncer
  101. Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: Effect of tumor microenvironment
  102. Sex Dimorphism in Late Gestational Sleep Fragmentation and Metabolic Dysfunction in Offspring Mice
  103. Resveratrol Attenuates Intermittent Hypoxia-Induced Macrophage Migration to Visceral White Adipose Tissue and Insulin Resistance in Male Mice
  104. Increased upper airway collapsibility in a mouse model of Marfan syndrome
  105. Reduced NADPH oxidase type 2 activity mediates sleep fragmentation-induced effects on TC1 tumors in mice
  106. Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia
  107. Early Intermittent Hypoxia Induces Proatherogenic Changes in Aortic Wall Macrophages in a Murine Model of Obstructive Sleep Apnea
  108. Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea
  109. The polymorphic and contradictory aspects of intermittent hypoxia
  110. Brain Tissue Hypoxia and Oxidative Stress Induced by Obstructive Apneas is Different in Young and Aged Rats
  111. Sleep apnea awakens cancer
  112. Intermittent Hypoxia-induced Changes in Tumor-associated Macrophages and Tumor Malignancy in a Mouse Model of Sleep Apnea
  113. Fragmented Sleep Accelerates Tumor Growth and Progression through Recruitment of Tumor-Associated Macrophages and TLR4 Signaling
  114. Atrial fibrosis in a chronic murine model of obstructive sleep apnea: mechanisms and prevention by mesenchymal stem cells
  115. Oxygen diffusion and consumption in extracellular matrix gels: Implications for designing three-dimensional cultures
  116. Intermittent hypoxia increases melanoma metastasis to the lung in a mouse model of sleep apnea
  117. Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea
  118. Potential Role of Adult Stem Cells in Obstructive Sleep Apnea
  119. Intermittent hypoxia enhances cancer progression in a mouse model of sleep apnoea
  120. Early and mid-term effects of obstructive apneas in myocardial injury and inflammation
  121. Tissue Oxygenation in Brain, Muscle, and Fat in a Rat Model of Sleep Apnea: Differential Effect of Obstructive Apneas and Intermittent Hypoxia
  122. Potential Role of Bone Marrow Mesenchymal Stem Cells in Obstructive Sleep Apnea
  123. Mesenchymal stem cells reduce inflammation in a rat model of obstructive sleep apnea
  124. Effects of heated humidification on nasal inflammation in a CPAP rat model
  125. Changes in oxygen partial pressure of brain tissue in an animal model of obstructive apnea
  126. One-lung overventilation does not induce inflammation in the normally ventilated contralateral lung
  127. Upper airway collapse and reopening induce inflammation in a sleep apnoea model
  128. Continuous Positive Airway Pressure (CPAP) Induces Early Nasal Inflammation
  129. Upper-Airway Inflammation Triggered by Vibration in a Rat Model of Snoring
  130. Rheology of Passive and Adhesion-Activated Neutrophils Probed by Atomic Force Microscopy
  131. Vibration Enhances Interleukin-8 Release in a Cell Model of Snoring-Induced Airway Inflammation