All Stories

  1. Normalization of Oxygen Levels Induces a Metabolic Reprogramming in Livers Exposed to Intermittent Hypoxia Mimicking Obstructive Sleep Apnea
  2. Low-Cost, Open-Source Device for Simultaneously Subjecting Rodents to Different Circadian Cycles of Light, Food, and Temperature
  3. Lung Micrometastases Display ECM Depletion and Softening While Macrometastases Are 30-Fold Stiffer and Enriched in Fibronectin
  4. Multi-Step Extracellular Matrix Remodelling and Stiffening in the Development of Idiopathic Pulmonary Fibrosis
  5. Experimental Models to Study End-Organ Morbidity in Sleep Apnea: Lessons Learned and Future Directions
  6. Lung Extracellular Matrix Hydrogels-Derived Vesicles Contribute to Epithelial Lung Repair
  7. Characterization of 3D Printed Metal-PLA Composite Scaffolds for Biomedical Applications
  8. hLMSC Secretome Affects Macrophage Activity Differentially Depending on Lung-Mimetic Environments
  9. Aging Impairs Reverse Remodeling and Recovery of Ventricular Function after Isoproterenol-Induced Cardiomyopathy
  10. Baseline Stiffness Modulates the Non-Linear Response to Stretch of the Extracellular Matrix in Pulmonary Fibrosis
  11. Human experimental models: seeking to enhance multiscale research in sleep apnoea
  12. Heterogeneity of Melanoma Cell Responses to Sleep Apnea-Derived Plasma Exosomes and to Intermittent Hypoxia
  13. Image-Based Method to Quantify Decellularization of Tissue Sections
  14. Oxygen Biosensors and Control in 3D Physiomimetic Experimental Models
  15. Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells
  16. Experimental Setting for Applying Mechanical Stimuli to Study the Endothelial Response of Ex Vivo Vessels under Realistic Pathophysiological Environments
  17. Metabolic dysfunction in OSA: Is there something new under the sun?
  18. Open access spreadsheet application for learning spontaneous breathing mechanics and mechanical ventilation
  19. The effect of chronic intermittent hypoxia in cardiovascular gene expression is modulated by age in a mice model of sleep apnea
  20. Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma
  21. Impact of sleep fragmentation, heart failure, and their combination, on the gut microbiome
  22. Intrahepatic Expression of Fatty Acid Translocase CD36 Is Increased in Obstructive Sleep Apnea
  23. The conventional isoproterenol-induced heart failure model does not consistently mimic the diaphragmatic dysfunction observed in patients
  24. Understanding the pathophysiological mechanisms of cardiometabolic complications in obstructive sleep apnoea: towards personalised treatment approaches
  25. ERS International Congress, Madrid, 2019: highlights from the Sleep and Clinical Physiology Assembly
  26. Biophysically Preconditioning Mesenchymal Stem Cells Improves Treatment of Ventilator-Induced Lung Injury
  27. Lung cancer aggressiveness in an intermittent hypoxia murine model of postmenopausal sleep apnea
  28. Obesity, sleep apnea, and cancer
  29. Chronic Sleep Fragmentation Mimicking Sleep Apnea Does Not Worsen Left-Ventricular Function in Healthy and Heart Failure Mice
  30. Obstructive sleep apnea intensifies stroke severity following middle cerebral artery occlusion
  31. Cancer and Sleep Apnea: Cutaneous Melanoma as a Case Study
  32. Differential effect of intermittent hypoxia and sleep fragmentation on PD-1/PD-L1 upregulation
  33. Effects of Sustained and Intermittent Hypoxia on Human Lung Cancer Cells
  34. Late Breaking Abstract - Fetal blood hypoxia/reoxygenation swings are reduced by placental oxygen transfer in a model ovine pregnancy with sleep apnea
  35. Lung extracellular matrix hydrogel for 3D bioprinting of lung mesenchymal stem cells
  36. Early Career Members at the Lung Science Conference and the Sleep and Breathing Conference 2019
  37. Placental oxygen transfer reduces hypoxia-reoxygenation swings in fetal blood in a sheep model of gestational sleep apnea
  38. Biomechanical Response of Lung Epithelial Cells to Iron Oxide and Titanium Dioxide Nanoparticles
  39. Aortic remodelling induced by obstructive apneas is normalized with mesenchymal stem cells infusion
  40. Highlights from the 2018 European Respiratory Society International Congress: sleep and clinical physiology
  41. Effect of age on the cardiovascular remodelling induced by chronic intermittent hypoxia as a murine model of sleep apnoea
  42. Why ERS Early Career Members should attend the International Congress 2019 in Madrid
  43. Preview of Sleep and Breathing Conference 2019 and report on Early Career Member international collaboration
  44. Differential Oxygenation in Tumor Microenvironment Modulates Macrophage and Cancer Cell Crosstalk: Novel Experimental Setting and Proof of Concept
  45. Soluble PD-L1 is a potential biomarker of cutaneous melanoma aggressiveness and metastasis in obstructive sleep apnoea patients
  46. Age‐dependent hypoxia‐induced PD‐L1 upregulation in patients with obstructive sleep apnoea
  47. Escherichia coli lipopolysaccharide induces alveolar epithelial cell stiffening
  48. Gas Partial Pressure in Cultured Cells: Patho-Physiological Importance and Methodological Approaches
  49. Sleep-Disordered Breathing Is Independently Associated With Increased Aggressiveness of Cutaneous Melanoma
  50. Intermittent Hypoxia Severity in Animal Models of Sleep Apnea
  51. Passive Stiffness of Left Ventricular Myocardial Tissue Is Reduced by Ovariectomy in a Post-menopause Mouse Model
  52. Aging Reduces Intermittent Hypoxia–induced Lung Carcinoma Growth in a Mouse Model of Sleep Apnea
  53. Overnight Change in Urinary Prostacyclin and Thromboxane in Obstructive Sleep Apnea
  54. Intermittent hypoxia and cancer: Undesirable bed partners?
  55. Clinical physiology and sleep: highlights from the European Respiratory Society Congress 2018 presented by early career members
  56. Intermittent Hypoxia Mimicking Sleep Apnea Increases Passive Stiffness of Myocardial Extracellular Matrix. A Multiscale Study
  57. Early Career Members at the ERS Lung Science Conference: cell-matrix interactions in lung disease and regeneration
  58. Zooming in on the ERS fellowships and the International Congress
  59. Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea
  60. Exosomal Cargo Properties, Endothelial Function and Treatment of Obesity Hypoventilation Syndrome: A Proof of Concept Study
  61. Intermittent Hypoxia Is Associated With High Hypoxia Inducible Factor-1α but Not High Vascular Endothelial Growth Factor Cell Expression in Tumors of Cutaneous Melanoma Patients
  62. Biomarkers of carcinogenesis and tumour growth in patients with cutaneous melanoma and obstructive sleep apnoea
  63. Alzheimer’s Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea
  64. Bioengineered Lungs: A Challenge and An Opportunity
  65. Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia
  66. Early Career Members at the ERS International Congress 2017: highlights from the Assemblies
  67. A prospective multicenter cohort study of cutaneous melanoma
  68. Early Career Members at the ERS LSC 2017: mechanistic overlap between chronic lung injury and cancer
  69. Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules
  70. Clinical physiology and sleep: insights from the European Respiratory Society Congress 2017
  71. Frequency and magnitude of intermittent hypoxia modulate endothelial wound healing in a cell culture model of sleep apnea
  72. Obstructive Sleep Apnea and Atherosclerosis: Both the Gut Microbiome and Hypercapnia Matter
  73. Hypoxia-induced PD-L1/PD-1 crosstalk impairs T-cell function in sleep apnoea
  74. Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice
  75. Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea
  76. Apnea del sueño y agresividad tumoral
  77. Visceral White Adipose Tissue after Chronic Intermittent and Sustained Hypoxia in Mice
  78. Sleep apnoea, insulin resistance and diabetes: the first step is in the fat
  79. Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea
  80. Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36
  81. Chronic intermittent hypoxia mimicking sleep apnoea increases spontaneous tumorigenesis in mice
  82. Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery
  83. Altered CD8+ T-Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep Apnea
  84. Early effects of continuous positive airway pressure in a rodent model of allergic rhinitis
  85. Tumor Cell Malignant Properties Are Enhanced by Circulating Exosomes in Sleep Apnea
  86. Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice
  87. Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice
  88. A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea
  89. Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation
  90. Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung
  91. Does obstructive sleep apnea confer risk to induce or enhance tumor malignancy?
  92. Intermittent Hypoxia-Induced Cardiovascular Remodeling Is Reversed by Normoxia in a Mouse Model of Sleep Apnea
  93. Obstructive sleep apnea and Fuhrman grade in patients with clear cell renal cell carcinoma treated surgically
  94. Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice
  95. Microarray-based analysis of plasma cirDNA epigenetic modification profiling in xenografted mice exposed to intermittent hypoxia
  96. Relación entre apnea del sueño y cáncer
  97. Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: Effect of tumor microenvironment
  98. Sex Dimorphism in Late Gestational Sleep Fragmentation and Metabolic Dysfunction in Offspring Mice
  99. Resveratrol Attenuates Intermittent Hypoxia-Induced Macrophage Migration to Visceral White Adipose Tissue and Insulin Resistance in Male Mice
  100. Increased upper airway collapsibility in a mouse model of Marfan syndrome
  101. Reduced NADPH oxidase type 2 activity mediates sleep fragmentation-induced effects on TC1 tumors in mice
  102. Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia
  103. Early Intermittent Hypoxia Induces Proatherogenic Changes in Aortic Wall Macrophages in a Murine Model of Obstructive Sleep Apnea
  104. Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea
  105. The polymorphic and contradictory aspects of intermittent hypoxia
  106. Brain Tissue Hypoxia and Oxidative Stress Induced by Obstructive Apneas is Different in Young and Aged Rats
  107. Sleep apnea awakens cancer
  108. Intermittent Hypoxia-induced Changes in Tumor-associated Macrophages and Tumor Malignancy in a Mouse Model of Sleep Apnea
  109. Fragmented Sleep Accelerates Tumor Growth and Progression through Recruitment of Tumor-Associated Macrophages and TLR4 Signaling
  110. Atrial fibrosis in a chronic murine model of obstructive sleep apnea: mechanisms and prevention by mesenchymal stem cells
  111. Oxygen diffusion and consumption in extracellular matrix gels: Implications for designing three-dimensional cultures
  112. Intermittent hypoxia increases melanoma metastasis to the lung in a mouse model of sleep apnea
  113. Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea
  114. Potential Role of Adult Stem Cells in Obstructive Sleep Apnea
  115. Intermittent hypoxia enhances cancer progression in a mouse model of sleep apnoea
  116. Early and mid-term effects of obstructive apneas in myocardial injury and inflammation
  117. Tissue Oxygenation in Brain, Muscle, and Fat in a Rat Model of Sleep Apnea: Differential Effect of Obstructive Apneas and Intermittent Hypoxia
  118. Potential Role of Bone Marrow Mesenchymal Stem Cells in Obstructive Sleep Apnea
  119. Mesenchymal stem cells reduce inflammation in a rat model of obstructive sleep apnea
  120. Effects of heated humidification on nasal inflammation in a CPAP rat model
  121. Changes in oxygen partial pressure of brain tissue in an animal model of obstructive apnea
  122. One-lung overventilation does not induce inflammation in the normally ventilated contralateral lung
  123. Upper airway collapse and reopening induce inflammation in a sleep apnoea model
  124. Continuous Positive Airway Pressure (CPAP) Induces Early Nasal Inflammation
  125. Upper-Airway Inflammation Triggered by Vibration in a Rat Model of Snoring
  126. Rheology of Passive and Adhesion-Activated Neutrophils Probed by Atomic Force Microscopy
  127. Vibration Enhances Interleukin-8 Release in a Cell Model of Snoring-Induced Airway Inflammation