All Stories

  1. Enteroaggregative Escherichia clade I from Nigeria

    Article • April 2026, openRxiv

    Professor Iruka Okeke

  2. Refining the Serine Protease Autotransporters of Enterobacteriaceae (SPATE) gene detection in Enteroaggregative Escherichia coli genomes uncovers differential SPATE distribution by phylogeny

    Article • April 2026, openRxiv

    Professor Iruka Okeke

  3. Identification of Antibiofilm Agents against Salmonella enterica from the Pathogen Box Compound Library

    Article • February 2026, openRxiv

    Professor Iruka Okeke

  4. Genomic characterization of resistant Escherichia coli isolated from household water in municipal Ibadan, Nigeria

    Article • PLOS Water, February 2026, PLOS

    Professor Iruka Okeke

  5. Knowledge, Attitudes, and Perceptions Surrounding Antibiotic Use: Exploring Social Determinants of Antibiotic Misuse in Peri-Urban Nigeria

    Article • December 2025, Faculty of 1000, Ltd.

    Professor Iruka Okeke

  6. Community-led Strategies for Ameliorating Antimicrobial Resistance in Nigeria:  Research Protocol for a Participatory Action Research Project

    Article • September 2025, Faculty of 1000, Ltd.

    Professor Iruka Okeke

  7. Stakeholder Views on Lessons Learned for the Antimicrobial Resistance Panel from Previous International Science Panels

    Article • September 2025, Faculty of 1000, Ltd.

    Professor Iruka Okeke

  8. Genomic epidemiology of enteropathogenic Escherichia coli in southwestern Nigeria

    Article • PLoS Neglected Tropical Diseases, August 2025, PLOS

    Professor Iruka Okeke

  9. Barriers and facilitators to digital technology application for antimicrobial resistance surveillance: A co-produced qualitative synthesis

    Article • PLOS Global Public Health, July 2025, PLOS

    Professor Iruka Okeke

  10. Slow-growing Salmonella enterica serovariety Typhi mis-identified as serovariety Gallinarum in Ibadan, Nigeria

    Article • PLOS Global Public Health, July 2025, PLOS

    Professor Iruka Okeke

  11. Transmissible antimicrobial resistance in Escherichia coli isolated from household drinking water in Ibadan, Nigeria

    Article • PLOS One, May 2025, PLOS

    Dr Olutayo Israel Falodun, Professor Iruka Okeke

  12. Case Report: Detection of invasive mcr-10 harbouring Klebsiella quasipneumoniae subsp. similipneumoniae in a patient with chronic myeloid leukaemia.

    Article • March 2025, Faculty of 1000, Ltd.

    Professor Iruka Okeke

  13. Beyond high cost: Pharmaceutic low-resource setting barriers to antibacterial access

    Article • PLOS Global Public Health, March 2025, PLOS

    Professor Iruka Okeke

  14. Decentralising Bioinformatics Capacity: Lessons from Training Hospital Staff and Field Epidemiologists in Nigeria

    Article • American Journal of Laboratory Medicine, March 2025, Science Publishing Group

    Professor Iruka Okeke

  15. Genomic epidemiology of enteropathogenic Escherichia coli(EPEC) in southwestern Nigeria

    Article • February 2025, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  16. Genomic characterization of foodborne Salmonella enterica and Escherichia coli isolates from Saboba district and Bolgatanga Municipality Ghana

    Article • PLOS One, February 2025, PLOS

    Professor Iruka Okeke

  17. Transmissible antimicrobial resistance in Escherichia coli isolated from household drinking water in Ibadan, Nigeria

    Article • January 2025, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  18. Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium

    Article • Wellcome Open Research, January 2025, Faculty of 1000, Ltd.

    Souha Kanj, Professor Iruka Okeke

  19. Slow-growingSalmonella entericaTyphi mis-identified asSalmonellaGallinarum in Ibadan, Nigeria

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  20. Genetic basis for antimicrobial resistance inEscherichia coliisolated from household water in municipal Ibadan, Nigeria

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  21. Whole Genome Sequencing RevealsEnterobacter hormaecheias a Key Bloodstream Pathogen in Six Tertiary Care Hospitals in Southwestern Nigeria

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  22. Occurrence of Salmonella enterica in faecal sludge from Nigeria and genetic relatedness with strains associated with human infections in Africa

    Article • Journal of Applied Microbiology, November 2024, Oxford University Press (OUP)

    Professor Iruka Okeke

  23. A Systematic Review of Antibiotic Use in Humans in Nigeria and its Potential Contribution to Rising Antimicrobial Resistance

    Article • September 2024, Qeios Ltd

    Professor Iruka Okeke

  24. A Systematic Review of Antibiotic Use in Humans in Nigeria and its Potential Contribution to Rising Antimicrobial Resistance

    Article • July 2024, Qeios Ltd

    Professor Iruka Okeke

  25. NDM-1- and OXA-23-producing Acinetobacter baumannii in wastewater of a Nigerian hospital

    Article • Microbiology Spectrum, December 2023, ASM Journals

    Professor Iruka Okeke

  26. PCR diagnostics are insufficient for the detection of Diarrhoeagenic Escherichia coli in Ibadan, Nigeria

    Article • PLOS Global Public Health, August 2023, PLOS

    Professor Iruka Okeke

  27. Evaluation of fecal occult blood testing for rapid diagnosis of invasive diarrhea in young children

    Article • PLOS Global Public Health, July 2023, PLOS

    Professor Iruka Okeke

  28. Prevalence and whole genome phylogenetic analysis reveal genetic relatedness between antibiotic resistance Salmonella in hatchlings and older chickens from farms in Nigeria

    Article • Poultry Science, March 2023, Elsevier

    Professor Iruka Okeke

  29. Evaluation of Fecal Occult Blood Testing Kits for Rapid Point-of-Care Diagnosis of Invasive Diarrhea in Young Children

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  30. Insufficiency of PCR diagnostics for Detection of DiarrhoeagenicEscherichia coliin Ibadan, Nigeria

    Article • January 2023, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  31. Antibiofilm agents with therapeutic potential against enteroaggregative Escherichia coli

    Article • PLoS Neglected Tropical Diseases, October 2022, PLOS

    Professor Iruka Okeke

  32. Epidemiology and risk factors for diarrhoeagenic Escherichia coli carriage among children in northern Ibadan, Nigeria

    Article • September 2022, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  33. Establishing a national reference laboratory for antimicrobial resistance using a whole-genome sequencing framework: Nigeria’s experience

    Article • Microbiology, September 2022, Society for General Microbiology

    Professor Iruka Okeke

  34. Genomic characterization of invasive typhoidal and non-typhoidal Salmonella in southwestern Nigeria

    Article • PLoS Neglected Tropical Diseases, August 2022, PLOS

    Professor Iruka Okeke

  35. A bottom-up view of antimicrobial resistance transmission in developing countries

    Article • Nature Microbiology, May 2022, Springer Science + Business Media

    Professor Iruka Okeke

  36. Genomic characterization of invasive typhoidal and non-typhoidal Salmonella in southwestern Nigeria

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  37. Towards a fiercely urgent expansion of laboratory medicine in Africa

    Article • African Journal of Laboratory Medicine, December 2021, AOSIS Open Journals

    Professor Iruka Okeke

  38. Antibiofilm agents with therapeutic potential against enteroaggregative Escherichia coli

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Professor Iruka Okeke

  39. Twenty steps to ingrain power asymmetry in global health biomedical research

    Article • PLoS Biology, September 2021, PLOS

    Professor Iruka Okeke

  40. The importance of molecular diagnostics for infectious diseases in low-resource settings

    Article • Nature Reviews Microbiology, June 2021, Springer Science + Business Media

    Professor Iruka Okeke

  41. Bacteria autoaggregation: how and why bacteria stick together

    Article • Biochemical Society Transactions, June 2021, Portland Press Ltd.

    Professor Iruka Okeke

  42. Genomic Analysis of Antimicrobial Resistance and Resistance Plasmids in Salmonella Serovars from Poultry in Nigeria

    Article • Antibiotics, January 2021, MDPI AG

    Professor Iruka Okeke

  43. African laboratory medicine in the time of COVID-19

    Article • African Journal of Laboratory Medicine, December 2020, AOSIS Open Journals

    Professor Iruka Okeke

  44. A plasmid-encoded papB paralogue modulates autoaggregation of Escherichia coli transconjugants

    Article • December 2020, Springer Science + Business Media

    Professor Iruka Okeke

  45. A plasmid-encoded papB paralogue modulates autoaggregation of Escherichia coli transconjugants

    Article • BMC Research Notes, December 2020, Springer Science + Business Media

    Professor Iruka Okeke

  46. Leapfrogging laboratories: the promise and pitfalls of high-tech solutions for antimicrobial resistance surveillance in low-income settings

    Article • BMJ Global Health, December 2020, BMJ

    Professor Iruka Okeke

  47. A plasmid-encoded papB paralogue modulates autoaggregation of Escherichia coli transconjugants

    Article • October 2020, Springer Science + Business Media

    Professor Iruka Okeke

  48. Editorial overview: Paths of least resistance: surveillance, discovery, and innovation to address the other (antimicrobial resistance) pandemic

    Article • Current Opinion in Microbiology, October 2020, Elsevier

    Professor Iruka Okeke

  49. A plasmid-encoded papB paralogue modulates autoaggregation of Escherichia coli transconjugants

    Article • June 2020, Springer Science + Business Media

    Professor Iruka Okeke

  50. The Not so Good, the Bad and the Ugly: Differential Bacterial Adhesion and Invasion Mediated by Salmonella PagN Allelic Variants

    Article • Microorganisms, March 2020, MDPI AG

    Dr Alexey V Rakov, Professor Iruka Okeke

  51. Extending the breadth of African laboratory medicine

    Article • African Journal of Laboratory Medicine, December 2019, AOSIS Open Journals

    Professor Iruka Okeke

  52. A large self-transmissible resistance plasmid from Nigeria contains genes that ameliorate a carrying cost

    Article • Scientific Reports, December 2019, Springer Science + Business Media

    Professor Iruka Okeke, Dr Babatunde Odetoyin

  53. Quality assessment of bacterial identification and antimicrobial susceptibility testing in African national health laboratories, 2011 - 2016

    Article • African Journal of Laboratory Medicine, May 2019, AOSIS Open Journals

    Professor Iruka Okeke

  54. A large self-transmissible plasmid from Nigeria confers resistance to multiple antibacterials without a carrying cost

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Dr Babatunde Odetoyin, Professor Iruka Okeke

  55. The incidence and prevalence of hospital-acquired (carbapenem-resistant) Acinetobacter baumannii in Europe, Eastern Mediterranean and Africa: a systematic review and meta-analysis

    Article • Emerging Microbes & Infections, January 2019, Taylor & Francis

    Professor Iruka Okeke

  56. Antimicrobial resistance of Vibrio cholerae from sub-Saharan Africa: A systematic review

    Article • African Journal of Laboratory Medicine, December 2018, AOSIS Open Journals

    Professor Iruka Okeke

  57. Antimicrobial resistance surveillance in Africa: Successes, gaps and a roadmap for the future

    Article • African Journal of Laboratory Medicine, December 2018, AOSIS Open Journals

    Professor Iruka Okeke

  58. Building resources to meet evolving laboratory medicine challenges in Africa

    Article • African Journal of Laboratory Medicine, November 2018, AOSIS Open Journals

    Professor Iruka Okeke

  59. Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC): Supporting the transition from strategy to action

    Article • Wellcome Open Research, June 2018, Faculty of 1000, Ltd.

    Professor Iruka Okeke

  60. Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC): Supporting the transition from strategy to action

    Article • Wellcome Open Research, May 2018, Faculty of 1000, Ltd.

    Professor Iruka Okeke

  61. Interplay of surface factors in colonization by a diarrhea pathogen

    Article • mSphere, March 2018, ASM Journals

    Professor Iruka Okeke

  62. Enteroaggregative Escherichia coli Have Evolved Independently as Distinct Complexes within the E. coli Population with Varying Ability to Cause Disease

    Article • PLOS One, November 2014, PLOS

    Professor Iruka Okeke

  63. Dissemination of the Transmissible Quinolone-Resistance Gene qnrS1 by IncX Plasmids in Nigeria

    Article • PLOS One, October 2014, PLOS

    Professor Iruka Okeke

  64. Diagnostic schemes for reducing epidemic size of african viral hemorrhagic fever outbreaks

    Article • The Journal of Infection in Developing Countries, September 2014, Journal of Infection in Developing Countries

    Professor Iruka Okeke

  65. Comparative genomics of 274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    Prof. Dr. Bas E. Dutilh, Dr Robert A Edwards, Professor Iruka Okeke

  66. Cholera Outbreaks in Nigeria Are Associated with Multidrug Resistant Atypical El Tor and Non-O1/Non-O139 Vibrio cholerae

    Article • PLoS Neglected Tropical Diseases, February 2013, PLOS

    Dr Michel Abanto Marin, Professor Iruka Okeke

  67. Regional Dissemination of a Trimethoprim-Resistance Gene Cassette via a Successful Transposable Element

    Article • PLOS One, May 2012, PLOS

    Professor Iruka Okeke

  68. Vibrio cholerae O1 lineages driving cholera outbreaks during seventh cholera pandemic in Ghana

    Article • Infection Genetics and Evolution, December 2011, Elsevier

    Dr Michel Abanto Marin, Professor Iruka Okeke

  69. Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use

    Article • BMC Infectious Diseases, November 2011, Springer Science + Business Media

    Dr Babatunde Odetoyin, Professor Iruka Okeke

  70. Non-prescription antimicrobial use worldwide: a systematic review

    Article • The Lancet Infectious Diseases, September 2011, Elsevier

    Professor Iruka Okeke

  71. The Heat-Resistant Agglutinin Family Includes a Novel Adhesin from Enteroaggregative Escherichia coli Strain 60A

    Article • Journal of Bacteriology, July 2011, ASM Journals

    Professor Iruka Okeke

  72. Diagnostics as essential tools for containing antibacterial resistance

    Article • Drug Resistance Updates, April 2011, Elsevier

    Professor Iruka Okeke

  73. Ensuring Global Access to Quality Medicines: Role of the US Pharmacopeia

    Article • Journal of Pharmaceutical Sciences, April 2011, Elsevier

    Professor Iruka Okeke

  74. IS3 profiling identifies the enterohaemorrhagic Escherichia coli O-island 62 in a distinct enteroaggregative E. coli lineage

    Article • Gut Pathogens, January 2011, Springer Science + Business Media

    Professor Iruka Okeke

  75. Quinolone resistance in Escherichia coli from Accra, Ghana

    Article • BMC Microbiology, January 2011, Springer Science + Business Media

    Professor Iruka Okeke

  76. Multi-Locus Sequence Typing of Enteroaggregative Escherichia coli Isolates from Nigerian Children Uncovers Multiple Lineages

    Article • PLOS One, November 2010, PLOS

    Professor Iruka Okeke

  77. Carriage of diarrhoeagenic Escherichia coli by older children and adults in Accra, Ghana

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, July 2010, Oxford University Press (OUP)

    Professor Iruka Okeke

  78. A Pathoadaptive Deletion in an Enteroaggregative Escherichia coli Outbreak Strain Enhances Virulence in a Caenorhabditis elegans Model

    Article • Infection and Immunity, June 2010, ASM Journals

    Professor Iruka Okeke

  79. African Researchers Underrepresented

    Article • Science, May 2010, American Association for the Advancement of Science

    Professor Iruka Okeke

  80. Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil

    Article • BMC Microbiology, January 2010, Springer Science + Business Media

    Professor Iruka Okeke

  81. Cholera Vaccine Will Reduce Antibiotic Use

    Article • Science, August 2009, American Association for the Advancement of Science

    Professor Iruka Okeke

  82. Heat-Resistant Agglutinin 1 Is an Accessory Enteroaggregative Escherichia coli Colonization Factor

    Article • Journal of Bacteriology, May 2009, ASM Journals

    Professor Iruka Okeke

  83. The Escherichia coli Common Pilus and the Bundle-Forming Pilus Act in Concert during the Formation of Localized Adherence by Enteropathogenic E. coli

    Article • Journal of Bacteriology, February 2009, ASM Journals

    Professor Iruka Okeke

  84. The commonly-used DNA probe for diffusely-adherent Escherichia coli cross-reacts with a subset of enteroaggregative E. coli

    Article • BMC Microbiology, January 2009, Springer Science + Business Media

    Professor Iruka Okeke

  85. The Plasmid-Encoded Regulator Activates Factors Conferring Lysozyme Resistance on Enteropathogenic Escherichia coli Strains

    Article • Applied and Environmental Microbiology, November 2008, ASM Journals

    Professor Iruka Okeke

  86. Post-genomic challenges for collaborative research in infectious diseases

    Article • Nature Reviews Microbiology, August 2008, Springer Science + Business Media

    Professor Iruka Okeke

  87. Vibrio cholerae O1 from Accra, Ghana carrying a class 2 integron and the SXT element

    Article • Journal of Antimicrobial Chemotherapy, July 2008, Oxford University Press (OUP)

    Professor Iruka Okeke

  88. Connecting loose ends: a unique linear plasmid or a new model system?

    Article • Trends in Microbiology, May 2008, Elsevier

    Professor Iruka Okeke

  89. Growing Problem of Multidrug-Resistant Enteric Pathogens in Africa

    Article • Emerging Infectious Diseases, November 2007, Centers for Disease Control and Prevention (CDC)

    Professor Iruka Okeke

  90. A Second Large Plasmid Encodes Conjugative Transfer and Antimicrobial Resistance in O119:H2 and Some Typical O111 Enteropathogenic Escherichia coli Strains

    Article • Journal of Bacteriology, June 2007, ASM Journals

    Professor Iruka Okeke

  91. EnteroaggregativeEscherichia coliRelated to Uropathogenic Clonal Group A

    Article • Emerging Infectious Diseases, May 2007, Centers for Disease Control and Prevention (CDC)

    Professor Iruka Okeke

  92. Error-Prone DNA Repair System in Enteroaggregative Escherichia coli Identified by Subtractive Hybridization

    Article • Journal of Bacteriology, March 2007, ASM Journals

    Professor Iruka Okeke

  93. Diagnostic Insufficiency in Africa

    Article • Clinical Infectious Diseases, May 2006, Oxford University Press (OUP)

    Professor Iruka Okeke

  94. Antimicrobial resistance in developing countries. Part II: strategies for containment

    Article • The Lancet Infectious Diseases, September 2005, Elsevier

    Professor Iruka Okeke

  95. Antimicrobial resistance in developing countries. Part I: recent trends and current status

    Article • The Lancet Infectious Diseases, August 2005, Elsevier

    Professor Iruka Okeke

  96. Stopping the Spread of Drug-Resistant Malaria

    Article • Science, December 2004, American Association for the Advancement of Science

    Professor Iruka Okeke

  97. Antibiotic resistance of faecal Escherichia coli from healthy volunteers from eight developing countries

    Article • Journal of Antimicrobial Chemotherapy, November 2004, Oxford University Press (OUP)

    Professor Iruka Okeke

  98. Molecular Epidemiology of the Iron Utilization Genes of Enteroaggregative Escherichia coli

    Article • Journal of Clinical Microbiology, January 2004, ASM Journals

    Professor Iruka Okeke

  99. Etiology of Acute Diarrhea in Adults in Southwestern Nigeria

    Article • Journal of Clinical Microbiology, October 2003, ASM Journals

    Professor Iruka Okeke

  100. Antibiotic-Resistant Cell-Detaching Escherichia coli Strains from Nigerian Children

    Article • Journal of Clinical Microbiology, January 2002, ASM Journals

    Professor Iruka Okeke

  101. Enteroaggregative Escherichia coli

    Article • The Lancet Infectious Diseases, December 2001, Elsevier

    Professor Iruka Okeke

  102. Bacteriological quality of skin-moisturizing creams and lotions distributed in a tropical developing country

    Article • Journal of Applied Microbiology, November 2001, Wiley

    Professor Iruka Okeke

  103. Comparative Sequence Analysis of the Plasmid-Encoded Regulator of Enteropathogenic Escherichia coliStrains

    Article • Infection and Immunity, September 2001, ASM Journals

    Professor Iruka Okeke

  104. Microbiological investigation of an outbreak of acute gastroenteritis in Niger State, Nigeria

    Article • Clinical Microbiology and Infection, September 2001, Elsevier

    Professor Iruka Okeke

  105. Dissemination of Antibiotic‐Resistant Bacteria across Geographic Borders

    Article • Clinical Infectious Diseases, August 2001, Oxford University Press (OUP)

    Professor Iruka Okeke

  106. espC Pathogenicity Island of Enteropathogenic Escherichia coli Encodes an Enterotoxin

    Article • Infection and Immunity, January 2001, ASM Journals

    Professor Fernando Navarro-Garcia, Professor Iruka Okeke

  107. Antibiotic Resistance in Escherichia coli from Nigerian Students, 1986-1998

    Article • August 2000, Centers for Disease Control and Prevention (CDC)

    Professor Iruka Okeke

  108. Heterogeneous Virulence of EnteroaggregativeEscherichia coliStrains Isolated from Children in Southwest Nigeria

    Article • The Journal of Infectious Diseases, January 2000, Oxford University Press (OUP)

    Professor Iruka Okeke

  109. Antimicrobial spectrum ofAlchornea cordifolia leaf extract

    Article • Phytotherapy Research, February 1999, Wiley

    Professor Iruka Okeke

  110. Socioeconomic and Behavioral Factors Leading to Acquired Bacterial Resistance to Antibiotics in Developing Countries

    Article • Emerging Infectious Diseases, February 1999, Centers for Disease Control and Prevention (CDC)

    Professor Iruka Okeke