All Stories

  1. FFAR4 drives stem cell fate toward lipid- and iron-storing enterocytes protecting human enteroids from ferroptosis
  2. The Duodenal Microenvironment in Functional Dyspepsia
  3. Time-Restricted Feeding Reinforces Gut Rhythmicity by Restoring Rhythms in Intestinal Metabolism in a Jetlag Mouse Model
  4. Bitter-tasting drugs tune GDF15 and GLP-1 expression via bitter taste or motilin receptors in the intestine of patients with obesity
  5. SCFAs switch stem cell fate through HDAC inhibition to improve barrier integrity in 3D intestinal organoids from patients with obesity
  6. The Acute Effect of Hydroxychloroquine Sulfate on Hunger, the Plasma Concentration of Orexigenic Peptides and Hedonic Food Intake: A Pilot Study
  7. Time‐restricted eating for chronodisruption‐related chronic diseases
  8. Controlled light exposure and intermittent fasting as treatment strategies for metabolic syndrome and gut microbiome dysregulation in night shift workers
  9. Chronic jetlag reprograms gene expression in the colonic smooth muscle layer inducing diurnal rhythmicity in the effect of bile acids on colonic contractility
  10. Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity
  11. Reply to Erren et al. Chronodisruption: Origin, Roots, and Developments of an 18-Year-Old Concept. Comment on “Desmet et al. Time-Restricted Feeding in Mice Prevents the Disruption of the Peripheral Circadian Clocks and Its Metabolic Impact during Chro...
  12. Time-Restricted Feeding in Mice Prevents the Disruption of the Peripheral Circadian Clocks and Its Metabolic Impact during Chronic Jetlag
  13. The endocrine effects of bitter tastant administration in the gastrointestinal system: intragastric versus intraduodenal administration
  14. Chronodisruption by chronic jetlag impacts metabolic and gastrointestinal homeostasis in male mice
  15. The Function of Gastrointestinal Hormones in Obesity—Implications for the Regulation of Energy Intake
  16. Circadian clocks in the digestive system
  17. Involvement of the GHSR in the developmental programming and metabolic disturbances induced by maternal undernutrition
  18. Ghrelin inhibits autonomic response to gastric distension in rats by acting on vagal pathway
  19. Extra-oral bitter taste receptors: New targets against obesity?
  20. Night-time feeding of Bmal1−/− mice restores SCFA rhythms and their effect on ghrelin
  21. Influence of subliminal intragastric fatty acid infusion on subjective and physiological responses to positive emotion induction in healthy women: A randomized trial
  22. Review: Chemosensing of nutrients and non-nutrients in the human and porcine gastrointestinal tract
  23. Effect of acute Δ9-tetrahydrocannabinol administration on subjective and metabolic hormone responses to food stimuli and food intake in healthy humans: a randomized, placebo-controlled study
  24. Obesity alters adrenergic and chemosensory signaling pathways that regulate ghrelin secretion in the human gut
  25. Motilin: from gastric motility stimulation to hunger signalling
  26. Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis
  27. Therapeutic potential of ectopic olfactory and taste receptors
  28. The circadian clock regulates the diurnal levels of microbial short-chain fatty acids and their rhythmic effects on colon contractility in mice
  29. Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis
  30. Effects of caloric and noncaloric sweeteners on antroduodenal motility, gastrointestinal hormone secretion and appetite-related sensations in healthy subjects
  31. Intragastric quinine administration decreases hedonic eating in healthy women through peptide-mediated gut-brain signaling mechanisms
  32. Effect of motilin receptor activation on food intake and food timing
  33. Obesity Impairs Oligopeptide/Amino Acid-Induced Ghrelin Release and Smooth Muscle Contractions in the Human Proximal Stomach
  34. Chemoreceptors in the Gut
  35. The motilin agonist erythromycin increases hunger by modulating homeostatic and hedonic brain circuits in healthy women: a randomized, placebo-controlled study
  36. Manometric evaluation of the motilin receptor agonist camicinal (GSK962040) in humans
  37. Intragastric infusion of the bitter tastant quinine suppresses hormone release and antral motility during the fasting state in healthy female volunteers
  38. Abdominal vagus nerve stimulation as a new therapeutic approach to prevent postoperative ileus
  39. The role of nutrient sensing in the metabolic changes after gastric bypass surgery
  40. Intragastric infusion of denatonium benzoate attenuates interdigestive gastric motility and hunger scores in healthy female volunteers
  41. Differential brain responses to gradual intragastric nutrient infusion and gastric balloon distension: A role for gut peptides?
  42. The Sweetener-Sensing Mechanisms of the Ghrelin Cell
  43. Supplementation of oligofructose, but not sucralose, decreases high-fat diet induced body weight gain in mice independent of gustducin-mediated gut hormone release
  44. Subchronic treatment with grape-seed phenolics inhibits ghrelin production despite a short-term stimulation of ghrelin secretion produced by bitter-sensing flavanols
  45. Smooth muscle and neural dysfunction contribute to different phases of murine postoperative ileus
  46. The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway
  47. Chronobesity: role of the circadian system in the obesity epidemic
  48. The Gustatory Signaling Pathway and Bitter Taste Receptors Affect the Development of Obesity and Adipocyte Metabolism in Mice
  49. Role of the clock gene Bmal1 and the gastric ghrelin-secreting cell in the circadian regulation of the ghrelin-GOAT system
  50. The bitter truth about bitter taste receptors: beyond sensing bitter in the oral cavity
  51. Targeting extra-oral bitter taste receptors modulates gastrointestinal motility with effects on satiation
  52. Chemosensory signalling pathways involved in sensing of amino acids by the ghrelin cell
  53. Ghrelin receptor modulates T helper cells during intestinal inflammation
  54. Ghrelin
  55. Higher plasma motilin levels in obese patients decrease after Roux-en-Y gastric bypass surgery and regulate hunger
  56. Taste receptors in the gut tune the release of peptides in response to nutrients
  57. Motilin-induced gastric contractions signal hunger in man
  58. Endogenous motilin, but not ghrelin plasma levels fluctuate in accordance with gastric phase III activity of the migrating motor complex in man
  59. Shifting the Circadian Rhythm of Feeding in Mice Induces Gastrointestinal, Metabolic and Immune Alterations Which Are Influenced by Ghrelin and the Core Clock Gene Bmal1
  60. Taste receptors of the gut: emerging roles in health and disease
  61. Ghrelin signaling in the gut, its physiological properties, and therapeutic potential
  62. Ghrelin is involved in the paracrine communication between neurons and glial cells
  63. Systemic inflammation with enhanced brain activation contributes to more severe delay in postoperative ileus
  64. Nutrient sensing in the gut: new roads to therapeutics?
  65. Neurotransmitters involved in fast excitatory neurotransmission directly activate enteric glial cells
  66. GI functions of GPR39: novel biology
  67. Can small non-peptide motilin agonists force a breakthrough as gastroprokinetic drugs?
  68. Endocrine and smooth muscle responses of the bitter agonist, denatonium benzoate, in the stomach
  69. Peripheral “chicken” obestatin administration does not affect feed intake and gut muscle contractility of meat-type and layer-type chicks (Gallus gallus domesticus)
  70. Restricted feeding induces inflammation: Role of ghrelin and clock genes?
  71. Specific hunger- and satiety-induced tuning of guinea pig enteric nerve activity
  72. Sensing of Fatty Acids for Octanoylation of Ghrelin Involves a Gustatory G-Protein
  73. Relationship between aquaporin‐5 expression and saliva flow in streptozotocin‐induced diabetic mice?
  74. The migrating motor complex: control mechanisms and its role in health and disease
  75. Role of the AMP-activated protein kinase (AMPK) signaling pathway in the orexigenic effects of endogenous ghrelin
  76. Relationship between aquaporin-5 expression and saliva flow in streptozotocin-induced diabetic mice?
  77. GPR39, a Receptor of the Ghrelin Receptor Family, Plays a Role in the Regulation of Glucose Homeostasis in a Mouse Model of Early Onset Diet-Induced Obesity
  78. P.1.180: INFLUENCE OF NALOXONE AND METHYLNALTREXONE ON INTERDIGESTIVE GASTROINTESTINAL MOTILITY AND HUNGER SCORES IN MAN
  79. Review article: the role of gastric motility in the control of food intake
  80. Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying
  81. The role of alpha-gustducin, in the effect of T2R-agonists on the secretion and physiological effects of ghrelin
  82. Endocannabinoid control of gastric sensorimotor function in man
  83. Peptide receptors in the gut as therapeutic targets
  84. Colitis affects the smooth muscle and neural response to motilin in the rabbit antrum
  85. Motilin and ghrelin as prokinetic drug targets
  86. Targeting the ghrelin receptor to regulate food intake
  87. Influence of ghrelin on the gastric accommodation reflex and on meal-induced satiety in man
  88. Comments on Selected Recent Dysphagia Literature
  89. Effect of peripheral obestatin on food intake and gastric emptying in ghrelin-knockout mice
  90. Synthesis and characterization of site-specific biotinylated probes for the motilin receptor*
  91. Endogenous and exogenous ghrelin enhance the colonic and gastric manifestations of dextran sodium sulphate-induced colitis in mice
  92. Role of Ghrelin in the Relationship Between Hyperphagia and Accelerated Gastric Emptying in Diabetic Mice
  93. Characterization of myenteric neuropathy in the jejunum of spontaneously diabetic BB-rats
  94. Desensitization and internalization of the human motilin receptor is independent of the C-terminal tail
  95. Structure-Activity Relation of Erythromycin-Related Macrolides in Inducing Contractions and in Displacing Bound Motilin in Rabbit Duodenum
  96. Short exposure of oesophageal mucosa to bile acids, both in acidic and weakly acidic conditions, can impair mucosal integrity and provoke dilated intercellular spaces
  97. Effect of motilin on the discharge of rat hippocampal neurons responding to gastric distension and its potential mechanism
  98. Differences in motilin receptor desensitization after stimulation with motilin or motilides are due to alternative receptor trafficking
  99. Critical role of stress in increased oesophageal mucosa permeability and dilated intercellular spaces
  100. Effect of peripheral obestatin on gastric emptying and intestinal contractility in rodents
  101. Delineation of the motilin domain involved in desensitization and internalization of the motilin receptor by using full and partial antagonists
  102. Altered Gastrointestinal and Metabolic Function in the GPR39-Obestatin Receptor–Knockout Mouse
  103. Role of Endogenous Ghrelin in the Hyperphagia of Mice with Streptozotocin-Induced Diabetes
  104. Influence of Motilin on Gastric Fundus Tone and on Meal-Induced Satiety in Man: Role of Cholinergic Pathways
  105. Influence of ghrelin on interdigestive gastrointestinal motility in humans
  106. Influence of ghrelin on gastric emptying and meal-related symptoms in idiopathic gastroparesis
  107. Energy Homeostasis and Gastric Emptying in Ghrelin Knockout Mice
  108. Effects of ghrelin on hypothalamic glucose responding neurons in rats
  109. Motilin and erythromycin-A share a common binding site in the third transmembrane segment of the motilin receptor
  110. Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro
  111. The therapeutic effect of the neuropeptide hormone somatostatin on Schistosoma mansoni caused liver fibrosis
  112. Effect of repeated cycles of acute esophagitis and healing on esophageal peristalsis, tone, and length
  113. Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro
  114. Desensitization of the Human Motilin Receptor by Motilides
  115. Central, but not peripheral application of motilin increases c-Fos expression in hypothalamic nuclei in the rat brain
  116. Evidence for the presence of motilin, ghrelin, and the motilin and ghrelin receptor in neurons of the myenteric plexus
  117. Treatment with interleukin-11 affects plasma leptin levels in inflamed and non-inflamed rabbits
  118. Effect of ghrelin and growth hormone-releasing peptide 6 on septic ileus in mice
  119. Sequence, distribution and quantification of the motilin precursor in the cat
  120. Comparison of the prokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro
  121. Differences in the ability of motilides to induce motilin receptor internalization underly their desensitizing capacity
  122. Effects of Schistosoma mansoni infection on somatostatin and somatostatin receptor 2A expression in mouse ileum
  123. Ghrelin activates a subset of myenteric neurons in guinea-pig jejunum
  124. Motilin and erythromycin-A share a common binding site in the third transmembrane segment of the motilin receptor
  125. The C-terminal domain of motilin is required for complete homologous desensitization and endocytosis
  126. Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation
  127. Interaction of the Growth Hormone-Releasing Peptides Ghrelin and Growth Hormone-Releasing Peptide-6 with the Motilin Receptor in the Rabbit Gastric Antrum
  128. In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs
  129. The motilin pharmacophore in CHO cells expressing the human motilin receptor
  130. Generalized loss of inhibitory innervation reverses serotonergic inhibition into excitation in a rabbit model of TNBS-colitis
  131. Demonstration of a functional motilin receptor in TE671 cells from human cerebellum
  132. Effect of recombinant human interleukin-11 on motilin and substance P release in normal and inflamed rabbits
  133. Identification and expression of the motilin precursor in the guinea pig
  134. Contractile effects and intracellular Ca2+ signalling induced by motilin and erythromycin in the circular smooth muscle of human colon
  135. Motilin receptor density in inflamed and noninflamed tissue in rabbit TNBS-induced colitis
  136. Dose-Dependent Effects of Recombinant Human Interleukin-11 on Contractile Properties in Rabbit 2,4,6-Trinitrobenzene Sulfonic Acid Colitis
  137. Specific activation of TE671 cells from human cerebellum by motilin and motilides
  138. TNBS-colitis in rabbits reverses the inhibitory effects of 5-HT agonists on neural responses to excitatory effects
  139. Treatment with recombinant human IL-11 (rhIL-11) affects endocrine motilin and extrinsic substance P (SP) release but not receptor density in normal rabbits
  140. Sequence and characterization of cDNA encoding the motilin precursor from chicken, dog, cow and horse. Evidence of mosaic evolution in prepromotilin
  141. Differential changes in ACh-, motilin-, substance P-, and K+-induced contractility in rabbit colitis
  142. Region-specific antiproliferative effect of VIP and PACAP-(1—38) on rabbit enteric smooth muscle
  143. Motilin in human milk: Identification and stability during digestion
  144. Localization of motilin binding sites in subcellular fractions from rabbit antral and colonic smooth muscle tissue
  145. Isolation and sequence of cDNA encoding the motilin precursor from monkey intestine. Demonstration of the motilin precursor in the monkey brain
  146. Motilin induces gall bladder emptying and antral contractions in the fasted state in humans
  147. Differences between motilin- and muscarinic receptor-coupled Ca2+ signalling in a smooth muscle cell line of human jejunum
  148. Dose-dependent effects of interleukin-11 on contractile parameters in rabbit TNBS-colitis
  149. Motilin-and erythromycin-induced CA2+-signalling in myocytes from human colon
  150. Full length article
  151. Isolation and sequencing of the cDNA encoding the motilin precursor from sheep intestine
  152. Concentration-dependent stimulation of cholinergic motor nerves or smooth muscle by [Nle13]motilin in the isolated rabbit gastric antrum
  153. Demonstration and characterization of motilin-binding sites in the rabbit cerebellum
  154. Identification of Motilin mRNA in the Brain of Man and Rabbit. Conservation of Polymorphism of the Motilin Gene Across Species
  155. Isolation, sequence, and bioactivity of chicken motilin
  156. Antagonistic properties of [Phe3,Leu13]porcine motilin
  157. Motilin binding to microsmal and synaptosomal membranes from rabbit antrum and distal colon
  158. The motilin analog, OHM-11638, induces phase III-like contractions of the upper gut and enhances gastric emptying in the conscious dog
  159. Transduction mechanism of motilin and motilides in rabbit duodenal smooth muscle
  160. Purification and amino acid sequence of human motilin isolated from a motilin containing liver metastasis
  161. Motilin receptor: A model for development of prokinetics
  162. Partial Purification and Measurement of Motilin in Human Milk
  163. The Motilin Antagonist ANQ-11125 Blocks Motilide-Induced Contractions in Vitro in the Rabbit
  164. Distribution and characterization of motilin receptors in the cat
  165. Purification and amino acid sequence of motilin from cat small intestine
  166. Solubilization and Characterization of Motilin-receptor Complexes from Rabbit Antral Smooth Muscle Tissue
  167. d-Amino acid and alanine scans of the bioactive portion of porcine motilin
  168. Biotinylated [Leu13]-porcine motilin for use as a receptor probe
  169. D-amino acid and alanine scan of porcine motilin
  170. Distribution and characterization of motilin receptors in the cat
  171. Effect of erythromycin on gastric motility in controls and in diabetic gastroparesis
  172. Synthesis and in vitro evaluation of [Leu13]porcine motilin fragments
  173. Effect of motilin on gastric emptying in patients with diabetic gastroparesis
  174. Effect of erythromycin and of octreotide on motilin receptor density in the rabbit
  175. Motilin receptors of the rabbit colon
  176. Development of motilin receptors and of motilin- and erythromycin-induced contractility in rabbits
  177. The erythromycin derivative EM-523 is a potent motilin agonist in man and in rabbit
  178. Stress-induced changes in gastric emptying, postprandial motility, and plasma gut hormone levels in dogs
  179. Erythromycin is a motilin receptor agonist
  180. BINDING AND CONTRACTION-INDUCING ACTIVITY OF MOTILIN ANALOGUES