All Stories

  1. Multi-target gene therapy AUP1602-C to improve healing and quality of life for diabetic foot ulcer patients: a phase I, open-label, dose-finding study

    Article • Therapeutic Advances in Endocrinology and Metabolism, May 2024, SAGE Publications

    Igor Mierau

  2. Effect of multi-targeting bacterial gene therapy on tumour regression and survival in mouse models of ovarian and intraperitoneal cancer.

    Article • Journal of Clinical Oncology, June 2023, American Society of Clinical Oncology (ASCO)

    Igor Mierau

  3. Four in one—Combination therapy using live Lactococcus lactis expressing three therapeutic proteins for the treatment of chronic non-healing wounds

    Article • PLOS One, February 2022, PLOS

    Igor Mierau

  4. High-Level Expression of Lactobacillus β-Galactosidases in Lactococcus lactis Using the Food-Grade, Nisin-Controlled Expression System NICE

    Article • Journal of Agricultural and Food Chemistry, January 2010, American Chemical Society (ACS)

    Igor Mierau

  5. Article • Microbial Cell Factories, January 2006, Springer Science + Business Media

    Igor Mierau

  6. 10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis

    Article • Applied Microbiology and Biotechnology, October 2005, Springer Science + Business Media

    Igor Mierau

  7. Optimization of the Lactococcus lactis nisin-controlled gene expression system NICE for industrial applications

    Article • Microbial Cell Factories, May 2005, Springer Science + Business Media

    Igor Mierau

  8. Industrial-scale production and purification of a heterologous protein in Lactococcus lactis using the nisin-controlled gene expression system NICE: The case of lysostaphin

    Article • Microbial Cell Factories, May 2005, Springer Science + Business Media

    Igor Mierau

  9. Oligopeptidase O

    Article • January 2004, Elsevier

    Igor Mierau

  10. Controlled Modulation of Folate Polyglutamyl Tail Length by Metabolic Engineering of Lactococcus lactis

    Article • Applied and Environmental Microbiology, December 2003, ASM Journals

    Igor Mierau

  11. Increased Production of Folate by Metabolic Engineering of Lactococcus lactis

    Article • Applied and Environmental Microbiology, June 2003, ASM Journals

    Igor Mierau

  12. Metabolic engineering of Lactococcus lactis: the impact of genomics and metabolic modelling

    Article • Journal of Biotechnology, September 2002, Elsevier

    Igor Mierau

  13. Control of Folate Production in Lactic Acid Bacteria by Using Metabolic Engineering

    Article • January 2002, Springer Science + Business Media

    Igor Mierau

  14. Measurement of parameters of cholic acid kinetics in plasma using a microscale stable isotope dilution technique: application to rodents and humans

    Article • Journal of Lipid Research, November 2001, Elsevier

    Igor Mierau

  15. Improved Efficiency and Reliability of RT-PCR Using Tag-Extended RT Primers and Temperature Gradient PCR

    Article • BioTechniques, September 2001, Taylor & Francis

    Igor Mierau

  16. Bile Salt Hydrolase of Bifidobacterium longum—Biochemical and Genetic Characterization

    Article • Applied and Environmental Microbiology, June 2000, ASM Journals

    Igor Mierau

  17. Cholic Acid Is Accumulated Spontaneously, Driven by Membrane ΔpH, in Many Lactobacilli

    Article • Journal of Bacteriology, January 2000, ASM Journals

    Igor Mierau

  18. Purification and Characterization of Bovine Pancreatic Bile Salt-Activated Lipase

    Article • The Journal of Biochemistry, May 1999, Oxford University Press (OUP)

    Igor Mierau

  19. Cloning and analysis of the pepV dipeptidase gene of Lactococcus lactis MG1363

    Article • Journal of Bacteriology, June 1997, ASM Journals

    Igor Mierau

  20. Casein and Peptide Degradation in Lactic Acid Bacteria

    Article • Biotechnology and Genetic Engineering Reviews, April 1997, Taylor & Francis

    Igor Mierau

  21. The proteotytic systems of lactic acid bacteria

    Article • Antonie van Leeuwenhoek, October 1996, Springer Science + Business Media

    Igor Mierau

  22. Heterologous Expression and Characterization of RecombinantLactococcus lactisNeutral Endopeptidase (Neprilysin)

    Article • Archives of Biochemistry and Biophysics, September 1996, Elsevier

    Igor Mierau

  23. Fate of peptides in peptidase mutants of Lactococcus lactis

    Article • Molecular Microbiology, July 1996, Wiley

    Igor Mierau

  24. Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk

    Article • Journal of Bacteriology, May 1996, ASM Journals

    Igor Mierau

  25. Novel Insertion Sequence-like Element IS982 in Lactococci

    Article • Plasmid, May 1995, Elsevier

    Dr Gary M Dunny, Igor Mierau

  26. Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and construction of a chromosomal deletion mutant

    Article • Journal of Bacteriology, May 1994, ASM Journals

    Igor Mierau

  27. Cloning and sequencing of the gene for a lactococcal endopeptidase, an enzyme with sequence similarity to mammalian enkephalinase

    Article • Journal of Bacteriology, April 1993, ASM Journals

    Igor Mierau