All Stories

  1. AM-18002, a derivative of natural anmindenol A, enhances radiosensitivity in mouse breast cancer cells

    Article • PLoS ONE, April 2024, PLOS

    Prof. Hwayoung Yun

  2. SAR optimization studies on a novel series of 2-anilinopyrimidines as selective inhibitors against triple-negative breast cancer cell line MDA-MB-468

    Article • Bioorganic & Medicinal Chemistry Letters, December 2019, Elsevier

    Prof. Hwayoung Yun

  3. Divergent Synthetic Route to Oxidized Benzofulvene Sesquiterpenoids: Protecting-Group-Free Total Synthesis of Nicotianasesterpenes A, B, and a Polygonum Sesquiterpenoid

    Article • European Journal of Organic Chemistry, October 2019, Wiley

    Prof. Hwayoung Yun

  4. Asymmetric and Reduced Xanthene Fluorophores: Synthesis, Photochemical Properties, and Application to Activatable Fluorescent Probes for Detection of Nitroreductase

    Article • Molecules, September 2019, MDPI AG

    Prof. Hwayoung Yun

  5. Pharmacokinetic Evaluation of Metabolic Drug Interactions between Repaglinide and Celecoxib by a Bioanalytical HPLC Method for Their Simultaneous Determination with Fluorescence Detection

    Article • Pharmaceutics, August 2019, MDPI AG

    Prof. Hwayoung Yun

  6. A novel high-performance liquid chromatographic method combined with fluorescence detection for determination of ertugliflozin in rat plasma: Assessment of pharmacokinetic drug interaction potential of ertugliflozin with mefenamic acid and ketoconazole

    Article • Journal of Chromatography B, August 2019, Elsevier

    Prof. Hwayoung Yun

  7. Total Synthesis of Anmindenol A and Its Application to the Design, Synthesis, and Biological Evaluation of Derivatives Thereof

    Article • The Journal of Organic Chemistry, July 2019, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  8. Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells

    Article • Bioorganic Chemistry, March 2019, Elsevier

    Prof. Hwayoung Yun

  9. Discovery and SAR studies of novel 2-anilinopyrimidine-based selective inhibitors against triple-negative breast cancer cell line MDA-MB-468

    Article • Bioorganic & Medicinal Chemistry Letters, January 2019, Elsevier

    Prof. Hwayoung Yun

  10. Multiple Combination of Angelica gigas Extract and Mesenchymal Stem Cells Enhances Therapeutic Effect

    Article • Biological and Pharmaceutical Bulletin, December 2018, Pharmaceutical Society of Japan

    Prof. Hwayoung Yun

  11. A metabolite-derived protein modification integrates glycolysis with KEAP1–NRF2 signalling

    Article • Nature, October 2018, Springer Science + Business Media

    Prof. Hwayoung Yun

  12. Recent Advances in Synthesis of 4-Arylcoumarins

    Article • Molecules, September 2018, MDPI AG

    Prof. Hwayoung Yun

  13. Salvia miltiorrhiza enhances the survival of mesenchymal stem cells under ischemic conditions

    Article • Journal of Pharmacy and Pharmacology, June 2018, Wiley

    Prof. Hwayoung Yun

  14. Asymmetric Total Synthesis of (+)-(3E)-Pinnatifidenyne via Abnormally Regioselective Pd(0)-Catalyzed Endocyclization

    Article • The Journal of Organic Chemistry, January 2018, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  15. Stereoselective Synthesis of 1,4,5-Tri-cis-guaiane Sesquiterpene: First Total Synthesis of (−)-Dendroside C Aglycon

    Article • Organic Letters, January 2018, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  16. An Improved C-Deglycosylation of Mangiferin to Norathyriol

    Article • Organic Preparations and Procedures International, January 2018, Taylor & Francis

    Prof. Hwayoung Yun

  17. Beneficial effects of Cirsium japonicum var. maackii on menopausal symptoms in ovariectomized rats

    Article • Food & Function, January 2018, Royal Society of Chemistry

    Prof. Hwayoung Yun

  18. Total synthesis of (+)-brasilenyne via concise construction of an oxonane framework containing a 1,3-cis,cis-diene

    Article • Chemical Communications, January 2018, Royal Society of Chemistry

    Prof. Hwayoung Yun

  19. Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton

    Article • Organic Letters, December 2017, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  20. Studies on Total Synthesis of Giffonins A and D

    Article • Yakhak Hoeji, November 2017, The Pharmaceutical Society of Korea

    Prof. Hwayoung Yun

  21. Inhibition of acute lethal pulmonary inflammation by the IDO–AhR pathway

    Article • Proceedings of the National Academy of Sciences, July 2017, Proceedings of the National Academy of Sciences

    Prof. Hwayoung Yun

  22. Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis

    Article • Molecules, June 2017, MDPI AG

    Prof. Hwayoung Yun

  23. Concise and Efficient Synthesis of 3,7-Dioxo-5β-cholanic Acid via C3,C7-Selective Ketal Protection

    Article • Organic Preparations and Procedures International, March 2017, Taylor & Francis

    Prof. Hwayoung Yun

  24. Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis

    Article • Molecules, July 2016, MDPI AG

    Prof. Hwayoung Yun

  25. Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer

    Article • Angewandte Chemie, May 2016, Wiley

    Prof. Hwayoung Yun

  26. Versatile strategy for controlling the specificity and activity of engineered T cells

    Article • Proceedings of the National Academy of Sciences, January 2016, Proceedings of the National Academy of Sciences

    Prof. Hwayoung Yun

  27. A Practical and Eco-friendly Synthesis ofOxo-bile Acids

    Article • Organic Preparations and Procedures International, January 2016, Taylor & Francis

    Prof. Hwayoung Yun

  28. Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone

    Article • Organic & Biomolecular Chemistry, January 2016, Royal Society of Chemistry

    Professor Young-Ger Suh, Prof. Hwayoung Yun

  29. A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer

    Article • ACS Chemical Biology, August 2015, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  30. Redirection of Genetically Engineered CAR-T Cells Using Bifunctional Small Molecules

    Article • Journal of the American Chemical Society, February 2015, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  31. Synthesis and Synthesis-Based Structural Elucidation of (‒)-Macrosphelides J and K

    Article • Heterocycles, January 2015, Japan Institute of Heterocyclic Chemistry

    Prof. Hwayoung Yun

  32. Design and synthesis of a macrosphelide A-biotin chimera

    Article • Organic & Biomolecular Chemistry, July 2014, Royal Society of Chemistry

    Professor Young-Ger Suh, Prof. Hwayoung Yun, young kee shin

  33. Glucal-conjugated sterols as novel vascular leakage blocker: Structure–activity relationship focusing on the C17-side chain

    Article • European Journal of Medicinal Chemistry, March 2014, Elsevier

    Prof. Hwayoung Yun

  34. Identification and Validation of Cryptochrome Inhibitors That Modulate the Molecular Circadian Clock

    Article • ACS Chemical Biology, January 2014, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  35. Bispecific small molecule–antibody conjugate targeting prostate cancer

    Article • Proceedings of the National Academy of Sciences, October 2013, Proceedings of the National Academy of Sciences

    Prof. Hwayoung Yun

  36. Synthesis of 5,6-dihydrophenanthridines via N,O-acetal TMS ethers

    Article • Tetrahedron Letters, September 2013, Elsevier

    Prof. Hwayoung Yun

  37. Stereoselective Synthesis of 7-epi-Incarvilline

    Article • Organic Letters, January 2013, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  38. Design, Synthesis, and Biological Evaluation of Novel Deguelin-Based Heat Shock Protein 90 (HSP90) Inhibitors Targeting Proliferation and Angiogenesis

    Article • Journal of Medicinal Chemistry, December 2012, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  39. Heterocycle-linked Phenylbenzyl Amides as Novel TRPV1 Antagonists and Their TRPV1 Binding Modes: Constraint-Induced Enhancement of In Vitro and In Vivo Activities

    Article • Chemistry - An Asian Journal, December 2012, Wiley

    Prof. Hwayoung Yun

  40. Achiral auxiliary-assisted chiral transfer via microwave-accelerated aza-Claisen rearrangement: a short synthesis of (+)-1-hydroxyquinolizidinone

    Article • Tetrahedron Letters, September 2012, Elsevier

    Prof. Hwayoung Yun

  41. Ligand-Based Design, Synthesis, and Biological Evaluation of 2-Aminopyrimidines, a Novel Series of Receptor for Advanced Glycation End Products (RAGE) Inhibitors

    Article • Journal of Medicinal Chemistry, July 2012, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  42. Asymmetric Syntheses of 1-Deoxy-6,8a-di-epi-castanospermine and 1-Deoxy-6-epi-castanospermine

    Article • The Journal of Organic Chemistry, May 2012, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  43. A stereo-controlled access to functionalized macrolactams via an aza-Claisen rearrangement

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Prof. Hwayoung Yun

  44. Expedient Synthesis of Chiral Homoallylamines viaN,O-Acetal TMS Ethers and Its Application

    Article • Organic Letters, November 2011, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  45. A versatile synthetic approach to grandisol monoterpene pheromone

    Article • Archives of Pharmacal Research, September 2011, Springer Science + Business Media

    Prof. Hwayoung Yun

  46. Enantioselective Total Synthesis of a Natural Iridoid

    Article • Organic Letters, July 2011, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  47. Concise and Enantioselective Total Synthesis of 15-Deoxy-Δ12,14-Prostaglandin J2

    Article • The Journal of Organic Chemistry, November 2010, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  48. Concise Syntheses of (+)-Macrosphelides A and B: Studies on the Macro-Ring Closure Strategy

    Article • The Journal of Organic Chemistry, January 2009, American Chemical Society (ACS)

    Prof. Hwayoung Yun

  49. First total syntheses of (−)-macrosphelides J and K and elucidation of their absolute configuration

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Prof. Hwayoung Yun