All Stories

  1. Secular trends of sleep-wake patterns in Hong Kong preschoolers

    Article • Sleep Medicine, April 2023, Elsevier

    Dr Hugh Simon Lam

  2. World variation in head circumference for children from birth to 5 years and a comparison with the WHO standards

    Article • Archives of Disease in Childhood, March 2023, BMJ

    Dr Hugh Simon Lam

  3. Fitness of INTERGROWTH-21st birth weight standards for Chinese-ethnicity babies

    Article • Archives of Disease in Childhood Fetal & Neonatal, February 2023, BMJ

    Dr Hugh Simon Lam

  4. Neonatal outcome of infants with umbilical cord arterial pH less than 7

    Article • Acta Obstetricia Et Gynecologica Scandinavica, December 2022, Wiley

    Dr Hugh Simon Lam

  5. Mucosal Antibody Response to SARS-CoV-2 in Paediatric and Adult Patients: A Longitudinal Study

    Article • Pathogens, March 2022, MDPI AG

    Professor Paul KS Chan, Dr Hugh Simon Lam

  6. Using Electronic Health Records for Personalized Dosing of Intravenous Vancomycin in Critically Ill Neonates: Model and Web-Based Interface Development Study

    Article • JMIR Medical Informatics, January 2022, JMIR Publications Inc.

    Dr Hugh Simon Lam

  7. Likelihood of COVID-19 vaccination among primary school students in Hong Kong

    Article • Clinical Microbiology and Infection, January 2022, Elsevier

    Dr Hugh Simon Lam

  8. R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling

    Article • Blood Advances, November 2021, American Society of Hematology

    Dr Hugh Simon Lam

  9. Improving Consistency and Accuracy of Neonatal Amplitude-Integrated Electroencephalography

    Article • American Journal of Perinatology, October 2021, Thieme Publishing Group

    Dr Hugh Simon Lam

  10. The Mucosal and Serological Immune Responses to the Novel Coronavirus (SARS-CoV-2) Vaccines

    Article • Frontiers in Immunology, October 2021, Frontiers

    Dr Hugh Simon Lam

  11. Neural Speech Encoding in Infancy Predicts Future Language and Communication Difficulties

    Article • American Journal of Speech-Language Pathology, September 2021, American Speech-Language-Hearing Association (ASHA)

    Dr Hugh Simon Lam, Nikolay Novitskiy, Peggy Hiu Ying Chan

  12. Prenatal methylmercury exposure is associated with decrease heart rate variability in children

    Article • Environmental Research, September 2021, Elsevier

    Dr Hugh Simon Lam

  13. Early Development of Neural Speech Encoding Depends on Age but not Native Language Status: Evidence from Lexical Tone

    Article • Neurobiology of Language, July 2021, The MIT Press

    Nikolay Novitskiy, Dr Hugh Simon Lam

  14. The miR‐223/nuclear factor I‐A axis regulates inflammation and cellular functions in intestinal tissues with necrotizing enterocolitis

    Article • FEBS Open Bio, June 2021, Wiley

    Dr Hugh Simon Lam

  15. A child with SARS‐CoV2‐induced croup

    Article • Pediatric Pulmonology, April 2021, Wiley

    Dr Hugh Simon Lam

  16. Effects of selenium on coronary artery disease, type 2 diabetes and their risk factors: a Mendelian randomization study

    Article • European Journal of Clinical Nutrition, April 2021, Springer Science + Business Media

    Dr Hugh Simon Lam

  17. SARS-CoV-2 detection by nasal strips: A superior tool for surveillance of paediatric population

    Article • Journal of Infection, April 2021, Elsevier

    Dr Hugh Simon Lam

  18. The Use of Somatex Shunt for Fetal Pleural Effusion: A Cohort of 8 Procedures

    Article • Fetal Diagnosis and Therapy, January 2021, Karger Publishers

    Dr Hugh Simon Lam

  19. Vancomycin Prescribing Practices and Therapeutic Drug Monitoring for Critically Ill Neonatal and Pediatric Patients: A Survey of Physicians and Pharmacists in Hong Kong

    Article • Frontiers in Pediatrics, November 2020, Frontiers

    Dr Hugh Simon Lam

  20. SARS-CoV-2 detection by nasal strips: a superior tool for surveillance of pediatric populations

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Professor Paul KS Chan, Dr Hugh Simon Lam

  21. Association between genetic variations in GSH-related and MT genes and low-dose methylmercury exposure in children and women of childbearing age: a pilot study

    Article • Environmental Research, August 2020, Elsevier

    Dr Hugh Simon Lam

  22. Age of puberty and Sleep duration: Observational and Mendelian randomization study

    Article • Scientific Reports, February 2020, Springer Science + Business Media

    Dr Hugh Simon Lam

  23. A Prospective Cohort Study of Fecal miR-223 and miR-451a as Noninvasive and Specific Biomarkers for Diagnosis of Necrotizing Enterocolitis in Preterm Infants

    Article • Neonatology, January 2020, Karger Publishers

    Dr Hugh Simon Lam

  24. Sleep Duration and Adiposity in Children and Adults: Observational and Mendelian Randomization Studies

    Article • Obesity, May 2019, Wiley

    Dr Hugh Simon Lam

  25. Dysregulation of miR-431 and target gene FOXA1 in intestinal tissues of infants with necrotizing enterocolitis

    Article • The FASEB Journal, April 2019, Federation of American Societies For Experimental Biology (FASEB)

    Dr Hugh Simon Lam

  26. Plasma miR-1290 Is a Novel and Specific Biomarker for Early Diagnosis of Necrotizing Enterocolitis—Biomarker Discovery with Prospective Cohort Evaluation

    Article • The Journal of Pediatrics, February 2019, Elsevier

    Dr Hugh Simon Lam

  27. Sleep duration and risk of diabetes: Observational and Mendelian randomization studies

    Article • Preventive Medicine, February 2019, Elsevier

    Dr Hugh Simon Lam

  28. Methylmercury levels in commonly consumed fish and methylmercury exposure of children and women of childbearing age in Hong Kong, a high fish consumption community

    Article • Environmental Research, October 2018, Elsevier

    Dr Hugh Simon Lam

  29. Mortality and morbidity of extremely low birth weight infants in Hong Kong, 2010-2017: a single-centre review

    Article • Hong Kong Medical Journal, September 2018, Hong Kong Academy of Medicine Press

    Dr Hugh Simon Lam

  30. Vascular Endothelial Growth Factor and Ischemic Heart Disease Risk: A Mendelian Randomization Study

    Article • Journal of the American Heart Association, August 2017, Wolters Kluwer Health

    Dr Hugh Simon Lam

  31. Parental behaviors and sleep/wake patterns of infants and toddlers in Hong Kong, China

    Article • World Journal of Pediatrics, March 2017, Springer Science + Business Media

    Dr Hugh Simon Lam

  32. Duration of puberty in preterm girls

    Article • American Journal of Human Biology, January 2017, Wiley

    Dr Hugh Simon Lam

  33. Regulation of Circulating Hematopoietic Stem/Progenitor Cells in Preterm Infants with Septicemia

    Article • Stem Cells and Development, December 2016, Mary Ann Liebert Inc

    Dr Hugh Simon Lam

  34. Effect of l-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine on ischemic heart disease risk: A Mendelian randomization study

    Article • American Heart Journal, December 2016, Elsevier

    Dr Hugh Simon Lam

  35. Rapid Identification of Bacterial Antibiotic Resistance by qPCR in Infants with Gram-Negative Septicaemia: A Proof-of-Concept Study

    Article • Neonatology, October 2016, Karger Publishers

    Dr Hugh Simon Lam

  36. Prenatal dioxin exposure and neurocognitive development in Hong Kong 11-year-old children

    Article • Environmental Research, October 2016, Elsevier

    Dr Hugh Simon Lam

  37. Attitudes of Parents and Health Care Workers to Major Surgery for High-Risk Preterm Infants

    Article • The Journal of Pediatrics, July 2016, Elsevier

    Dr Hugh Simon Lam

  38. Pneumococcal carriage in young children after introduction of PCV13 in Hong Kong

    Article • Vaccine, July 2016, Elsevier

    Dr Hugh Simon Lam

  39. Dysregulated expression of arginine metabolic enzymes in human intestinal tissues of necrotizing enterocolitis and response of CaCO2 cells to bacterial components

    Article • The Journal of Nutritional Biochemistry, March 2016, Elsevier

    Dr Hugh Simon Lam

  40. Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis

    Article • Recent Patents on Inflammation & Allergy Drug Discovery, February 2016, Bentham Science Publishers

    Dr Hugh Simon Lam

  41. Gestational Age, Birthweight for Gestational Age, and Childhood Hospitalisations for Asthma and Other Wheezing Disorders

    Article • Paediatric and Perinatal Epidemiology, January 2016, Wiley

    Dr Hugh Simon Lam

  42. Impact of fetal and childhood mercury exposure on immune status in children

    Article • Environmental Research, January 2016, Elsevier

    Dr Hugh Simon Lam

  43. Life-Threatening Hemolytic Anemia after Intrapleural Instillation of OK-432 for Treatment of Congenital Chylothorax

    Article • Neonatology, January 2016, Karger Publishers

    Dr Hugh Simon Lam

  44. Late prematurity and adiposity in adolescents: Evidence from “Children of 1997” birth cohort

    Article • Obesity, September 2015, Wiley

    Dr Hugh Simon Lam

  45. Comparative MiRNA Expressional Profiles and Molecular Networks in Human Small Bowel Tissues of Necrotizing Enterocolitis and Spontaneous Intestinal Perforation

    Article • PLOS One, August 2015, PLOS

    Dr Hugh Simon Lam

  46. End-of-life decision-making for newborns: a 12-year experience in Hong Kong

    Article • Archives of Disease in Childhood Fetal & Neonatal, August 2015, BMJ

    Dr Hugh Simon Lam

  47. Gestational age and adolescent mental health: evidence from Hong Kong's ‘Children of 1997’ birth cohort

    Article • Archives of Disease in Childhood, June 2015, BMJ

    Dr Hugh Simon Lam

  48. Intranasal corticosteroids for mild childhood obstructive sleep apnea – a randomized, placebo-controlled study

    Article • Sleep Medicine, March 2015, Elsevier

    Dr Hugh Simon Lam

  49. The neonatal resuscitation algorithm organized cart is more efficient than the airway–breathing–circulation organized drawer

    Article • European Journal of Emergency Medicine, February 2015, Wolters Kluwer Health

    Dr Hugh Simon Lam

  50. The use of laboratory biomarkers for surveillance, diagnosis and prediction of clinical outcomes in neonatal sepsis and necrotising enterocolitis 

    Article • Archives of Disease in Childhood Fetal & Neonatal, January 2015, BMJ

    Dr Hugh Simon Lam

  51. Endothelial Function in Children With OSA and the Effects of Adenotonsillectomy

    Article • CHEST Journal, January 2015, Elsevier

    Dr Hugh Simon Lam

  52. Genome-wide Expression Profiles of Necrotizing Enterocolitis Versus Spontaneous Intestinal Perforation in Human Intestinal Tissues

    Article • Annals of Surgery, December 2014, Wolters Kluwer Health

    Dr Hugh Simon Lam

  53. A 4-Year Prospective Follow-up Study of Childhood OSA and Its Association With BP

    Article • CHEST Journal, June 2014, Elsevier

    Dr Hugh Simon Lam

  54. Sleep architecture in school-aged children with primary snoring

    Article • Sleep Medicine, March 2014, Elsevier

    Dr Hugh Simon Lam

  55. Study of Isobaric Interference in Quantification of Citrulline by Parallel Fragmentation Monitoring

    Article • Mass Spectrometry, January 2014, The Mass Spectrometry Society of Japan

    Dr Hugh Simon Lam

  56. A Double-Blind Randomised Controlled Trial of Fish Oil-Based versus Soy-Based Lipid Preparations in the Treatment of Infants with Parenteral Nutrition-Associated Cholestasis

    Article • Neonatology, January 2014, Karger Publishers

    Dr Hugh Simon Lam

  57. Acute and Chronic Effects of Sleep Duration on Blood Pressure

    Article • PEDIATRICS, December 2013, American Academy of Pediatrics (AAP)

    Dr Hugh Simon Lam

  58. Gut-Associated Biomarkers L-FABP, I-FABP, and TFF3 and LIT Score for Diagnosis of Surgical Necrotizing Enterocolitis in Preterm Infants

    Article • Annals of Surgery, December 2013, Wolters Kluwer Health

    Dr Hugh Simon Lam

  59. Neutrophil CD64 for Daily Surveillance of Systemic Infection and Necrotizing Enterocolitis in Preterm Infants

    Article • Clinical Chemistry, September 2013, AACC

    Dr Hugh Simon Lam

  60. Reduced flow-mediated vasodilation of brachial artery in children with primary snoring

    Article • International Journal of Cardiology, September 2013, Elsevier

    Dr Hugh Simon Lam

  61. Expression profile of cord blood neutrophils and dysregulation of HSPA1A and OLR1 upon challenge by bacterial peptidoglycan

    Article • Journal of Leukocyte Biology, August 2013, Society for Leukocyte Biology

    Dr Hugh Simon Lam

  62. A pilot randomized study to assess immunogenicity, reactogenicity, safety and tolerability of two human papillomavirus vaccines administered intramuscularly and intradermally to females aged 18–26 years

    Article • Vaccine, July 2013, Elsevier

    Professor Paul KS Chan, Dr Hugh Simon Lam

  63. Quantification of citrulline by parallel fragmentation monitoring — A novel method using graphitized carbon nanoparticles and MALDI-TOF/TOF mass spectrometry

    Article • Clinica Chimica Acta, May 2013, Elsevier

    Dr Hugh Simon Lam

  64. Long term neurocognitive impact of low dose prenatal methylmercury exposure in Hong Kong

    Article • Environment International, April 2013, Elsevier

    Dr Hugh Simon Lam

  65. Gastroschisis, omphalocele or something else?

    Article • Archives of Disease in Childhood Fetal & Neonatal, March 2013, BMJ

    Dr Hugh Simon Lam

  66. Prevalence of metabolic syndrome in a cohort of Chinese schoolchildren: comparison of two definitions and assessment of adipokines as components by factor analysis

    Article • BMC Public Health, March 2013, Springer Science + Business Media

    Dr Hugh Simon Lam

  67. IL-15 and macrophage secretory factors facilitate immune activation of neonatal natural killer cells by lipoteichoic acid

    Article • Cytokine, February 2013, Elsevier

    Dr Hugh Simon Lam

  68. Clinical outcomes of congenital diaphragmatic hernia without extracorporeal membrane oxygenation

    Article • Early Human Development, September 2012, Elsevier

    Dr Hugh Simon Lam

  69. Immunoregulatory Protein Profiles of Necrotizing Enterocolitis versus Spontaneous Intestinal Perforation in Preterm Infants

    Article • PLOS One, May 2012, PLOS

    Dr Hugh Simon Lam

  70. Follow up of aerobic capacity in children affected by severe acute respiratory syndrome

    Article • Respirology, March 2012, Wiley

    Dr Hugh Simon Lam

  71. Biomarkers in Neonatology: The Next Generation of Tests

    Article • Neonatology, January 2012, Karger Publishers

    Dr Hugh Simon Lam

  72. A Prospective Longitudinal Study to Estimate the “Adjusted Cortisol Percentile” in Preterm Infants

    Article • Pediatric Research, June 2011, Springer Science + Business Media

    Dr Hugh Simon Lam

  73. Use of prokinetics in the preterm infant

    Article • Current Opinion in Pediatrics, April 2011, Wolters Kluwer Health

    Dr Hugh Simon Lam

  74. Biomarkers for Late-Onset Neonatal Sepsis: Cytokines and Beyond

    Article • Clinics in Perinatology, September 2010, Elsevier

    Dr Hugh Simon Lam

  75. Early Diagnosis of Intra-Abdominal Inflammation and Sepsis by Neutrophil CD64 Expression in Newborns

    Article • Neonatology, August 2010, Karger Publishers

    Dr Hugh Simon Lam

  76. Host-response biomarkers for diagnosis of late-onset septicemia and necrotizing enterocolitis in preterm infants

    Article • Journal of Clinical Investigation, August 2010, American Society for Clinical Investigation

    Dr Hugh Simon Lam

  77. Serum levels of heavy metals in childhood eczema and skin diseases: Friends or foes

    Article • Pediatric Allergy and Immunology, March 2010, Wiley

    Dr Hugh Simon Lam

  78. Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis-a randomized placebo-controlled study

    Article • Pediatric Pulmonology, November 2009, Wiley

    Dr Hugh Simon Lam

  79. Rapid identification and differentiation of Gram-negative and Gram-positive bacterial bloodstream infections by quantitative polymerase chain reaction in preterm infants*

    Article • Critical Care Medicine, August 2009, Wolters Kluwer Health

    Dr Hugh Simon Lam

  80. Interrupter Respiratory Resistance in Healthy Chinese Preschool Children

    Article • CHEST Journal, August 2009, Elsevier

    Dr Hugh Simon Lam

  81. 50 Years Ago in The Journal of Pediatrics

    Article • The Journal of Pediatrics, July 2009, Elsevier

    Dr Hugh Simon Lam

  82. Attitudes Toward Neonatal Intensive Care Treatment of Preterm Infants With a High Risk of Developing Long-term Disabilities

    Article • PEDIATRICS, May 2009, American Academy of Pediatrics (AAP)

    Dr Hugh Simon Lam

  83. Rescue treatment of infants with intestinal failure and parenteral nutrition-associated cholestasis (PNAC) using a parenteral fish-oil-based lipid

    Article • Clinical Nutrition, April 2009, Elsevier

    Dr Hugh Simon Lam

  84. 50 Years Ago in The Journal of Pediatrics

    Article • The Journal of Pediatrics, February 2009, Elsevier

    Dr Hugh Simon Lam

  85. Renal screening in children after exposure to low dose melamine in Hong Kong: cross sectional study

    Article • BMJ, December 2008, BMJ

    Dr Hugh Simon Lam

  86. Successful Treatment of Multiple Subdural Empyemata Caused by <i>Mycoplasma hominis</i> in a Newborn

    Article • Neonatology, September 2008, Karger Publishers

    Professor Margaret Ip, Dr Hugh Simon Lam

  87. Transient Increase in Intraocular Pressure during a Dose-Tapering Regime of Systemic Dexamethasone in Preterm Infants

    Article • Ophthalmology, May 2008, Elsevier

    Dr Hugh Simon Lam

  88. Predictors for failed dose reduction of inhaled corticosteroids in childhood asthma

    Article • Respirology, May 2008, Wiley

    Dr Hugh Simon Lam

  89. Biochemical markers of neonatal sepsis

    Article • Pathology, February 2008, Elsevier

    Dr Hugh Simon Lam

  90. A Longitudinal Study to Establish the Normative Value and to Evaluate Perinatal Factors Affecting Intraocular Pressure in Preterm Infants

    Article • Investigative Ophthalmology & Visual Science, January 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Hugh Simon Lam

  91. Congenital Intrathoracic Stomach: Short Esophagus or Hiatal Hernia?

    Article • Neonatology, September 2007, Karger Publishers

    Dr Hugh Simon Lam

  92. Biomarkers in neonatal infection

    Article • Biomarkers in Medicine, June 2007, Future Medicine

    Dr Hugh Simon Lam

  93. High-Dose Oral Erythromycin Decreased the Incidence of Parenteral Nutrition-Associated Cholestasis in Preterm Infants

    Article • Gastroenterology, May 2007, Elsevier

    Dr Hugh Simon Lam

  94. Rapid diagnosis of cerebral sinovenous thrombosis complicating group B streptococcus meningitis by multidetector CT venography

    Article • Archives of Disease in Childhood Fetal & Neonatal, April 2007, BMJ

    Dr Hugh Simon Lam

  95. DIAGNOSTIC MARKERS IN NEONATAL SEPSIS

    Article • Fetal and Maternal Medicine Review, February 2007, Cambridge University Press

    Dr Hugh Simon Lam

  96. 50 Years Ago in The Journal of Pediatrics

    Article • The Journal of Pediatrics, February 2007, Elsevier

    Dr Hugh Simon Lam

  97. Renal artery thrombosis and ischaemia presenting as severe neonatal hypertension

    Article • Archives of Disease in Childhood Fetal & Neonatal, January 2007, BMJ

    Dr Hugh Simon Lam

  98. Congenital systemic Langerhans cell histiocytosis presenting as hydrops fetalis

    Article • Acta Paediatrica, January 2007, Wiley

    Dr Hugh Simon Lam

  99. Fetal methylmercury exposure as measured by cord blood mercury concentrations in a mother–infant cohort in Hong Kong

    Article • Environment International, January 2007, Elsevier

    Dr Hugh Simon Lam

  100. Cough frequency in children with mild asthma correlates with sputum neutrophil count

    Article • Thorax, September 2006, BMJ

    Dr Hugh Simon Lam

  101. Risk of Vitamin A Toxicity From Candy-Like Chewable Vitamin Supplements for Children

    Article • PEDIATRICS, August 2006, American Academy of Pediatrics (AAP)

    Dr Hugh Simon Lam

  102. Diagnostic markers for neonatal sepsis

    Article • Current Opinion in Pediatrics, April 2006, Wolters Kluwer Health

    Dr Hugh Simon Lam

  103. Insulin and obstructive sleep apnea in obese Chinese children

    Article • Pediatric Pulmonology, January 2006, Wiley

    Dr Hugh Simon Lam

  104. Sputum induction in children with asthma: A tertiary-center experience

    Article • Pediatric Pulmonology, January 2006, Wiley

    Dr Hugh Simon Lam

  105. Congenital systemic Langerhans cell histiocytosis presenting as hydrops fetalis

    Article • Acta Paediatrica, December 2005, Wiley

    Dr Hugh Simon Lam

  106. Are your hands clean enough for point-of-care electrolyte analysis?

    Article • Pathology, January 2005, Elsevier

    Dr Hugh Simon Lam

  107. Mal-Positioned Umbilical Venous Catheter Causing Liver Abscess in a Preterm Infant

    Article • Neonatology, January 2005, Karger Publishers

    Dr Hugh Simon Lam