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  1. Optimization of immunohistochemical detection of rat ESR2 proteins with well-validated monoclonal antibody PPZ0506

    Article • Molecular and Cellular Endocrinology, March 2021, Elsevier

    Dr Hirotaka Ishii

  2. Quantitative expression data of human estrogen receptor α variants in non-functioning pituitary adenomas obtained by reverse transcription-digital polymerase chain reaction analysis

    Article • Data in Brief, December 2020, Elsevier

    Dr Hirotaka Ishii

  3. Accurate assessment of estrogen receptor profiles in non-functioning pituitary adenomas using RT-digital PCR and immunohistochemistry

    Article • Life Sciences, November 2020, Elsevier

    Dr Hirotaka Ishii

  4. Identification of a novel C-terminally truncated estrogen receptor α variant (ERαi34) with constitutive transactivation and estrogen receptor antagonist resistance

    Article • Molecular and Cellular Endocrinology, March 2020, Elsevier

    Dr Hirotaka Ishii

  5. Identification of novel C-terminally truncated estrogen receptor β variant transcripts and their distribution in humans

    Article • Journal of Nippon Medical School, January 2020, Medical Association of Nippon Medical School

    Dr Hirotaka Ishii

  6. GnRH(1-5), a metabolite of gonadotropin-releasing hormone, enhances luteinizing hormone release via activation of kisspeptin neurons in female rats

    Article • Endocrine Journal, January 2020, Japan Endocrine Society

    Dr Hirotaka Ishii

  7. Applicability of Anti-Human Estrogen Receptor β Antibody PPZ0506 for the Immunodetection of Rodent Estrogen Receptor β Proteins

    Article • International Journal of Molecular Sciences, December 2019, MDPI AG

    Dr Hirotaka Ishii

  8. Co-expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats

    Article • Reproductive Medicine and Biology, March 2018, Wiley

    Dr Hirotaka Ishii

  9. Morphological Analysis of Trafficking and Processing of Anionic and Cationic Liposomes in Cultured Cells

    Article • ACTA HISTOCHEMICA ET CYTOCHEMICA, January 2018, Japan Society of Histochemistry & Cytochemistry

    Dr Hirotaka Ishii

  10. Suitable reference gene selection for gene expression studies in knee osteoarthritis synovium using quantitative PCR analysis

    Article • Connective Tissue Research, November 2017, Taylor & Francis

    Dr Hirotaka Ishii

  11. Characterization of rodent constitutively active estrogen receptor α variants and their constitutive transactivation mechanisms

    Article • General and Comparative Endocrinology, July 2017, Elsevier

    Dr Hirotaka Ishii

  12. Subunit profiling and functional characteristics of acetylcholine receptors in GT1-7 cells

    Article • The Journal of Physiological Sciences, June 2016, Springer Science + Business Media

    Dr Hirotaka Ishii

  13. Characterization of sevoflurane effects on Per2 expression using ex vivo bioluminescence imaging of the suprachiasmatic nucleus in transgenic rats

    Article • Neuroscience Research, June 2016, Elsevier

    Dr Hirotaka Ishii

  14. Establishment of an in vitro cell line experimental system for the study of inhalational anesthetic mechanisms

    Article • Neuroscience Letters, May 2016, Elsevier

    Dr Hirotaka Ishii

  15. Human C-terminally truncated ERα variants resulting from the use of alternative exons in the ligand-binding domain

    Article • Molecular and Cellular Endocrinology, April 2016, Elsevier

    Dr Hirotaka Ishii

  16. Puerperal and parental experiences alter rat preferences for pup odors via changes in the oxytocin system

    Article • Journal of Reproduction and Development, January 2016, Japanese Society of Animal Reproduction

    Dr Hirotaka Ishii

  17. Characterization of the fundamental properties of the N-terminal truncation (Δ exon 1) variant of estrogen receptor α in the rat

    Article • Gene, October 2015, Elsevier

    Dr Hirotaka Ishii

  18. Novel splicing events and post-transcriptional regulation of human estrogen receptor α E isoforms

    Article • The Journal of Steroid Biochemistry and Molecular Biology, January 2013, Elsevier

    Dr Hirotaka Ishii

  19. Somatostatin Inhibition of GnRH Neuronal Activity and the Morphological Relationship between GnRH and Somatostatin Neurons in Rats

    Article • Endocrinology, February 2012, Endocrine Society

    Dr Hirotaka Ishii

  20. Endogenous Synthesis of Corticosteroids in the Hippocampus

    Article • PLoS ONE, July 2011, PLOS

    Dr Hirotaka Ishii

  21. Complex organization of the 5′-untranslated region of the mouse estrogen receptor α gene: Identification of numerous mRNA transcripts with distinct 5′-ends

    Article • The Journal of Steroid Biochemistry and Molecular Biology, July 2011, Elsevier

    Dr Hirotaka Ishii

  22. Identification of C-terminally and N-terminally truncated estrogen receptor α variants in the mouse

    Article • The Journal of Steroid Biochemistry and Molecular Biology, March 2011, Elsevier

    Dr Hirotaka Ishii

  23. Identification of novel splicing events and post-transcriptional regulation of human estrogen receptor α F isoforms☆

    Article • Molecular and Cellular Endocrinology, February 2011, Elsevier

    Dr Hirotaka Ishii

  24. Hippocampal Synthesis of Sex Steroids and Corticosteroids: Essential for Modulation of Synaptic Plasticity

    Article • Frontiers in Endocrinology, January 2011, Frontiers

    Dr Hirotaka Ishii

  25. Semicomprehensive Analysis of the Postnatal Age-Related Changes in the mRNA Expression of Sex Steroidogenic Enzymes and Sex Steroid Receptors in the Male Rat Hippocampus

    Article • Endocrinology, December 2010, Endocrine Society

    Dr Hirotaka Ishii

  26. Voltage-gated Ca2+ channel mRNAs and T-type Ca2+ currents in rat gonadotropin-releasing hormone neurons

    Article • The Journal of Physiological Sciences, January 2010, Springer Science + Business Media

    Dr Hirotaka Ishii

  27. Alternative promoter usage and alternative splicing of the rat estrogen receptor α gene generate numerous mRNA variants with distinct 5′-ends

    Article • The Journal of Steroid Biochemistry and Molecular Biology, January 2010, Elsevier

    Dr Hirotaka Ishii

  28. Comparison between Hippocampus-Synthesized and Circulation-Derived Sex Steroids in the Hippocampus

    Article • Endocrinology, November 2009, Endocrine Society

    Dr Hirotaka Ishii

  29. Retinoic Acid Stimulates 17β-Estradiol and Testosterone Synthesis in Rat Hippocampal Slice Cultures

    Article • Endocrinology, September 2009, Endocrine Society

    Dr Hirotaka Ishii

  30. Comparison of sex-steroid synthesis between neonatal and adult rat hippocampus

    Article • Biochemical and Biophysical Research Communications, July 2009, Elsevier

    Dr Hirotaka Ishii

  31. Ca2+Channels and Ca2+-Activated K+Channels in Adult Rat Gonadotrophin-Releasing Hormone Neurones

    Article • Journal of Neuroendocrinology, April 2009, Wiley

    Dr Hirotaka Ishii

  32. Cetrorelix, a Gonadotropin-Releasing Hormone Antagonist, Induces the Expression of Melatonin Receptor 1a in the Gonadotropin-Releasing Hormone Neuronal Cell Line GT1–7

    Article • Neuroendocrinology, January 2009, Karger Publishers

    Dr Hirotaka Ishii

  33. Gene structures, biochemical characterization and distribution of rat melatonin receptors

    Article • The Journal of Physiological Sciences, December 2008, Springer Science + Business Media

    Dr Hirotaka Ishii

  34. Estrogen synthesis in the brain—Role in synaptic plasticity and memory

    Article • Molecular and Cellular Endocrinology, August 2008, Elsevier

    Dr Hirotaka Ishii

  35. Activation of A-Type γ-Amino Butyric Acid Receptors Excites Gonadotrophin-Releasing Hormone Neurones Isolated from Adult Rats

    Article • Journal of Neuroendocrinology, May 2008, Wiley

    Dr Hirotaka Ishii

  36. 17β-Estradiol at Physiological Concentrations Augments Ca2+-Activated K+Currents via Estrogen Receptor β in the Gonadotropin-Releasing Hormone Neuronal Cell Line GT1-7

    Article • Endocrinology, February 2008, Endocrine Society

    Dr Hirotaka Ishii

  37. Local Production of Estrogen and its Rapid Modulatory Action on Synaptic Plasticity

    Article • January 2008, Springer Science + Business Media

    Dr Hirotaka Ishii

  38. Rat GnRH Neurons Exhibit Large Conductance Voltage- and Ca2+-Activated K+ (BK) Currents and Express BK Channel mRNAs

    Article • The Journal of Physiological Sciences, January 2008, Physiological Society of Japan

    Dr Hirotaka Ishii

  39. Local Production of Sex Hormones and Their Modulation of Hippocampal Synaptic Plasticity

    Article • The Neuroscientist, August 2007, SAGE Publications

    Dr Hirotaka Ishii

  40. Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons

    Article • Journal of Neurochemistry, February 2007, Wiley

    Dr Hirotaka Ishii

  41. Enhancement of nitric oxide production by association of nitric oxide synthase with N-methyl-d-aspartate receptors via postsynaptic density 95 in genetically engineered Chinese hamster ovary cells: real-time fluorescence imaging using nitric oxide sens...

    Article • Journal of Neurochemistry, March 2006, Wiley

    Dr Hirotaka Ishii

  42. Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: Synaptocrinology

    Article • Neuroscience, March 2006, Elsevier

    Dr Hirotaka Ishii

  43. Local Neurosteroid Production in the Hippocampus: Influence on Synaptic Plasticity of Memory

    Article • Neuroendocrinology, January 2006, Karger Publishers

    Dr Hirotaka Ishii

  44. Role of Cytochrome P450 in Synaptocrinology: Endogenous Estrogen Synthesis in the Brain Hippocampus

    Article • Drug Metabolism Reviews, January 2006, Taylor & Francis

    Dr Hirotaka Ishii

  45. Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons

    Article • Proceedings of the National Academy of Sciences, December 2003, Proceedings of the National Academy of Sciences

    Dr Hirotaka Ishii

  46. Hippocampal cytochrome P450s synthesize brain neurosteroids which are paracrine neuromodulators of synaptic signal transduction

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, February 2003, Elsevier

    Dr Hirotaka Ishii