All Stories

  1. Molecular Bases of Neurodegenerative Disorders of the Retina

    Article • August 2017, Bentham Science Publishers

    Dr Hemant Khanna

  2. Long-term rescue of cone photoreceptor degeneration in retinitis pigmentosa 2 ( RP2 )-knockout mice by gene replacement therapy

    Article • Human Molecular Genetics, September 2015, Oxford University Press (OUP)

    Dr Hemant Khanna

  3. Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice

    Article • Cytoskeleton, September 2015, Wiley

    Dr Hemant Khanna

  4. Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition

    Article • Scientific Reports, June 2015, Nature

    Dr Hemant Khanna

  5. Role of small GTPases in polarized vesicle transport to primary cilium

    Article • Research and Reports in Biology, February 2015, Taylor & Francis

    Dr Hemant Khanna

  6. Cilia in photoreceptors

    Article • January 2015, Elsevier

    Dr Hemant Khanna

  7. Loss of Raf-1 Kinase Inhibitory Protein Delays Early-Onset Severe Retinal Ciliopathy inCep290rd16Mouse

    Article • Investigative Ophthalmology & Visual Science, September 2014, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Hemant Khanna

  8. Ablation of the X-Linked Retinitis Pigmentosa 2 (Rp2) Gene in Mice Results in Opsin Mislocalization and Photoreceptor Degeneration

    Article • Investigative Ophthalmology & Visual Science, July 2013, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Hemant Khanna

  9. New mechanisms and treatment modalities for retinal degenerative diseases

    Article • Journal of Clinical & Experimental Ophthalmology, January 2013, OMICS Publishing Group

    Dr Hemant Khanna

  10. Retina ciliopathies: From genes to mechanisms and treatment

    Article • Vision Research, December 2012, Elsevier

    Dr Hemant Khanna

  11. Ciliary signaling cascades in photoreceptors

    Article • Vision Research, December 2012, Elsevier

    Dr Hemant Khanna

  12. Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis

    Article • Journal of Clinical Investigation, August 2012, American Society for Clinical Investigation

    Dr Hemant Khanna

  13. Ciliary transition zone (TZ) proteins RPGR and CEP290: role in photoreceptor cilia and degenerative diseases

    Article • Expert Opinion on Therapeutic Targets, May 2012, Informa Healthcare

    Dr Hemant Khanna

  14. Rd9 Is a Naturally Occurring Mouse Model of a Common Form of Retinitis Pigmentosa Caused by Mutations in RPGR-ORF15

    Article • PLoS ONE, May 2012, PLOS

    Dr Hemant Khanna

  15. Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis

    Article • Journal of Clinical Investigation, April 2012, American Society for Clinical Investigation

    Dr Hemant Khanna

  16. Tackling Primary Cilia Dysfunction in Photoreceptor Degenerative Diseases of the Eye

    Article • International Journal of Ophthalmic Pathology, January 2012, OMICS Publishing Group

    Dr Hemant Khanna

  17. Expression and Functional Roles of Caspase-5 in Inflammatory Responses of Human Retinal Pigment Epithelial Cells

    Article • Investigative Ophthalmology & Visual Science, November 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Hemant Khanna

  18. Functional Analysis of Retinitis Pigmentosa 2 (RP2) Protein Reveals Variable Pathogenic Potential of Disease-Associated Missense Variants

    Article • PLoS ONE, June 2011, PLOS

    Dr Hemant Khanna

  19. Accumulation of the Raf-1 Kinase Inhibitory Protein (Rkip) Is Associated with Cep290-mediated Photoreceptor Degeneration in Ciliopathies

    Article • Journal of Biological Chemistry, June 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Hemant Khanna

  20. XIAP Therapy Increases Survival of Transplanted Rod Precursors in a Degenerating Host Retina

    Article • Investigative Ophthalmology & Visual Science, March 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Hemant Khanna

  21. Expression and localization of the ciliary disease protein retinitis pigmentosa GTPase regulator in mammalian kidney

    Article • Kidney International, September 2010, Elsevier

    Dr Hemant Khanna

  22. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy

    Article • Journal of Clinical Investigation, April 2010, American Society for Clinical Investigation

    Dr Hemant Khanna

  23. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy

    Article • Journal of Clinical Investigation, March 2010, American Society for Clinical Investigation

    Dr Hemant Khanna, Dr Hannes Lohi

  24. Multiprotein Complexes of Retinitis Pigmentosa GTPase Regulator (RPGR), a Ciliary Protein Mutated in X-Linked Retinitis Pigmentosa (XLRP)

    Article • December 2009, Springer Science + Business Media

    Dr Hemant Khanna

  25. RPGR-containing protein complexes in syndromic and non-syndromic retinal degeneration due to ciliary dysfunction

    Article • Journal of Genetics, December 2009, Springer Science + Business Media

    Dr Hemant Khanna

  26. Widespread expression of the Supv3L1 mitochondrial RNA helicase in the mouse

    Article • Transgenic Research, November 2009, Springer Science + Business Media

    Dr Hemant Khanna

  27. A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies

    Article • Nature Genetics, May 2009, Nature

    Dr Hemant Khanna

  28. CP110 Suppresses Primary Cilia Formation through Its Interaction with CEP290, a Protein Deficient in Human Ciliary Disease

    Article • Developmental Cell, August 2008, Elsevier

    Dr Hemant Khanna

  29. FGF19 Exhibits Neuroprotective Effects on Adult Mammalian Photoreceptors In Vitro

    Article • Investigative Ophthalmology & Visual Science, April 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Hemant Khanna

  30. Retinitis Pigmentosa GTPase Regulator (RPGR) protein isoforms in mammalian retina: Insights into X-linked Retinitis Pigmentosa and associated ciliopathies

    Article • Vision Research, February 2008, Elsevier

    Dr Hemant Khanna

  31. Mutations in TOPORS Cause Autosomal Dominant Retinitis Pigmentosa with Perivascular Retinal Pigment Epithelium Atrophy

    Article • The American Journal of Human Genetics, November 2007, Elsevier

    Dr Hemant Khanna

  32. Centrosomal-ciliary geneCEP290/NPHP6 mutations result in blindness with unexpected sparing of photoreceptors and visual brain: implications for therapy of Leber congenital amaurosis

    Article • Human Mutation, January 2007, Wiley

    Dr Hemant Khanna

  33. The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

    Article • Nature Genetics, May 2006, Nature

    Dr Hemant Khanna

  34. Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin

    Article • Nature Genetics, February 2005, Nature

    Dr Hemant Khanna

  35. Role of residues constituting the 2β1 strand of domain II in the biological activity of anthrax protective antigen

    Article • FEMS Microbiology Letters, May 2001, Oxford University Press (OUP)

    Dr Yogendra Singh, Dr Hemant Khanna

  36. Anthrax‐toxin‐mediated delivery of a 19 kDa antigen of Mycobacterium tuberculosis into the cytosol of mammalian cells

    Article • Biotechnology and Applied Biochemistry, April 2001, Wiley

    Dr Yogendra Singh, Dr Hemant Khanna

  37. Participation of Residue F552 in Domain III of the Protective Antigen in the Biological Activity of Anthrax Lethal Toxin

    Article • Biological Chemistry, January 2001, De Gruyter

    Dr Yogendra Singh, Dr Hemant Khanna

  38. Anthrax toxin-mediated delivery of cholera toxin-A subunit into the cytosol of mammalian cells

    Article • Biotechnology and Applied Biochemistry, August 2000, Wiley

    Dr Yogendra Singh, Dr Hemant Khanna