All Stories

  1. Distinct functions for the membrane proximal ectodomain region (MPER) of HIV-1 gp41 in cell-free and cell-cell viral transmission and cell-cell fusion

    Article • Journal of Biological Chemistry, March 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Heidi E Drummer

  2. Antibody Responses to a Quadrivalent Hepatitis C Viral-Like Particle Vaccine Adjuvanted with Toll-Like Receptor 2 Agonists

    Article • Viral Immunology, February 2018, Mary Ann Liebert Inc

    Dr Heidi E Drummer

  3. Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes

    Article • Journal of Virology, February 2018, ASM Journals

    Dr Heidi E Drummer

  4. The antigen-binding fragment of MAb24 in complex with a peptide from Hepatitis C Virus E2 epitope I (412-423)

    Article • February 2018, Protein Data Bank, Rutgers University

    Dr Heidi E Drummer

  5. A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81

    Article • Wellcome Open Research, September 2017, Faculty of 1000, Ltd.

    Dr Heidi E Drummer

  6. Generating broadly neutralizing antibody responses against hepatitis C using a vaccine candidate

    Article • Hepatology, February 2017, Wiley

    Dr Heidi E Drummer

  7. An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry

    Article • Journal of Virology, December 2016, ASM Journals

    Dr Heidi E Drummer

  8. The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact

    Article • BMC Medicine, August 2016, Springer Science + Business Media

    Dr Heidi E Drummer

  9. Calsyntenin-1 mediates hepatitis C virus replication

    Article • Journal of General Virology, August 2016, Society for General Microbiology

    Dr Heidi E Drummer

  10. The Potential Impact of a Hepatitis C Vaccine for People Who Inject Drugs: Is a Vaccine Needed in the Age of Direct-Acting Antivirals?

    Article • PLoS ONE, May 2016, PLOS

    mr Jack Stone, Dr Heidi E Drummer

  11. Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region

    Article • Journal of Virology, September 2015, ASM Journals

    Dr Heidi E Drummer

  12. The role of a hepatitis C virus vaccine: modelling the benefits alongside direct-acting antiviral treatments

    Article • BMC Medicine, August 2015, Springer Science + Business Media

    Dr Heidi E Drummer, mr Jack Stone

  13. Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection

    Article • PLoS ONE, May 2015, PLOS

    Dr Heidi E Drummer

  14. Antibodies to the high‐density lipoprotein receptor SR‐B1 potently inhibit hepatitis C virus replication in vivo : New avenues for preventing reinfection of the liver following transplantation

    Article • Hepatology, September 2014, Wolters Kluwer Health

    Dr Heidi E Drummer

  15. Challenges to the development of vaccines to hepatitis C virus that elicit neutralizing antibodies

    Article • Frontiers in Microbiology, July 2014, Frontiers

    Dr Heidi E Drummer

  16. A Summary of the 20th International Symposium on Hepatitis C Virus and Related Viruses

    Article • Gastroenterology, July 2014, Elsevier

    Dr Heidi E Drummer

  17. Detection of HCV-Specific IFN-γ Responses in HCV Antibody and HCV RNA Negative Injecting Drug Users

    Article • Hepatitis Monthly, January 2014, Kowsar Medical Institute

    Dr Heidi E Drummer

  18. High Rates of Hepatitis C Virus Reinfection and Spontaneous Clearance of Reinfection in People Who Inject Drugs: A Prospective Cohort Study

    Article • PLoS ONE, November 2013, PLOS

    Dr Heidi E Drummer

  19. Allosteric Modulation of the HIV-1 gp120-gp41 Association Site by Adjacent gp120 Variable Region 1 (V1) N-Glycans Linked to Neutralization Sensitivity

    Article • PLoS Pathogens, April 2013, PLOS

    Dr Heidi E Drummer

  20. Forced virus evolution reveals functional crosstalk between the disulfide bonded region and membrane proximal ectodomain region of HIV-1 gp41

    Article • Retrovirology, January 2013, Springer Science + Business Media

    Dr Heidi E Drummer

  21. Identification of specific regions in hepatitis C virus core, NS2 and NS5A that genetically interact with p7 and co-ordinate infectious virus production

    Article • Journal of Viral Hepatitis, September 2012, Wiley

    Dr Heidi E Drummer

  22. In silico directed mutagenesis identifies the CD 81/claudin‐1 hepatitis C virus receptor interface

    Article • Cellular Microbiology, September 2012, Wiley

    Dr Heidi E Drummer

  23. Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2

    Article • Biochemical Journal, April 2012, Portland Press Ltd.

    Dr Heidi E Drummer

  24. Role for the Terminal Clasp of HIV-1 gp41 Glycoprotein in the Initiation of Membrane Fusion

    Article • Journal of Biological Chemistry, October 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Heidi E Drummer

  25. Hepatitis C Virus (HCV) Envelope Glycoproteins E1 and E2 Contain Reduced Cysteine Residues Essential for Virus Entry

    Article • Journal of Biological Chemistry, July 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Heidi E Drummer

  26. The SR-BI Partner PDZK1 Facilitates Hepatitis C Virus Entry

    Article • PLoS Pathogens, October 2010, PLOS

    Dr Heidi E Drummer

  27. Claudin Association with CD81 Defines Hepatitis C Virus Entry

    Article • Journal of Biological Chemistry, April 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Heidi E Drummer

  28. Role for the disulfide-bonded region of human immunodeficiency virus type 1 gp41 in receptor-triggered activation of membrane fusion function

    Article • Biochemical and Biophysical Research Communications, April 2010, Elsevier

    Dr Heidi E Drummer

  29. Delivery of a foreign epitope by sharing amino acid residues with the carrier matrix

    Article • Journal of Virological Methods, June 2009, Elsevier

    Dr Hans Jurgen Netter, Dr Heidi E Drummer

  30. T CD8 response in diverse outcomes of recurrent exposure to hepatitis C virus

    Article • Immunology and Cell Biology, May 2009, Wiley

    Dr Heidi E Drummer

  31. High incidence of hepatitis C virus reinfection in a cohort of injecting drug users

    Article • Hepatology, October 2008, Wiley

    Dr Heidi E Drummer

  32. An N-terminal glycine-rich sequence contributes to retrovirus trimer of hairpins stability

    Article • Biochemical and Biophysical Research Communications, August 2007, Elsevier

    Dr Heidi E Drummer

  33. Neutralizing antibodies in patients with chronic hepatitis C infection treated with (Peg)-interferon/ribavirin

    Article • Journal of Clinical Virology, August 2007, Elsevier

    Dr Heidi E Drummer

  34. Recent Advances in Our Understanding of Receptor Binding, Viral Fusion and Cell Entry of Hepatitis C Virus: New Targets for the Design of Antiviral Agents

    Article • Antiviral Chemistry and Chemotherapy, August 2007, SAGE Publications

    Dr Heidi E Drummer

  35. Expression and Characterization of a Minimal Hepatitis C Virus Glycoprotein E2 Core Domain That Retains CD81 Binding

    Article • Journal of Virology, June 2007, ASM Journals

    Dr Heidi E Drummer

  36. Functional Links between the Fusion Peptide-proximal Polar Segment and Membrane-proximal Region of Human Immunodeficiency Virus gp41 in Distinct Phases of Membrane Fusion

    Article • Journal of Biological Chemistry, May 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Heidi E Drummer

  37. Induction of neutralizing antibody responses to hepatitis C virus with synthetic peptide constructs incorporating both antibody and T‐helper epitopes

    Article • Immunology and Cell Biology, January 2007, Wiley

    Dr Heidi E Drummer

  38. A self-adjuvanting multiepitope immunogen that induces a broadly cross-reactive antibody to hepatitis C virus

    Article • Hepatology, January 2007, Wiley

    Dr Heidi E Drummer

  39. Determinants of CD81 dimerization and interaction with hepatitis C virus glycoprotein E2

    Article • Biochemical and Biophysical Research Communications, March 2005, Elsevier

    Dr Heidi E Drummer

  40. Hepatitis C Virus Glycoprotein E2 Contains a Membrane-proximal Heptad Repeat Sequence That Is Essential for E1E2 Glycoprotein Heterodimerization and Viral Entry

    Article • Journal of Biological Chemistry, May 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Heidi E Drummer

  41. Expression and biochemical analysis of the entire HIV-2 gp41 ectodomain: determinants of stability map to N- and C-terminal sequences outside the 6-helix bundle core

    Article • FEBS Letters, May 2004, Wiley

    Professor Bostjan Kobe, Dr Heidi E Drummer

  42. Functional Evolution of the HIV-1 Envelope Glycoprotein 120 Association Site of Glycoprotein 41

    Article • Journal of Biological Chemistry, August 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Heidi E Drummer

  43. Cell surface expression of functional hepatitis C virus E1 and E2 glycoproteins

    Article • FEBS Letters, June 2003, Wiley

    Dr Heidi E Drummer

  44. Identification of the Hepatitis C Virus E2 Glycoprotein Binding Site on the Large Extracellular Loop of CD81

    Article • Journal of Virology, November 2002, ASM Journals

    Dr Heidi E Drummer

  45. Equine rhinitis A virus: structural proteins and immune response

    Article • Journal of General Virology, July 2001, Society for General Microbiology

    Dr Heidi E Drummer

  46. Glycosylation of a Synthetic Peptide Representing a T-Cell Determinant of Influenza Virus Hemagglutinin Results in Loss of Recognition by CD4+ T-Cell Clones

    Article • Virology, March 1994, Elsevier

    Dr Heidi E Drummer

  47. Conserved Determinants for CD4+ T Cells within the Light Chain of the H3 Hemagglutinin Molecule of Influenza Virus

    Article • Virology, February 1994, Elsevier

    Dr Heidi E Drummer

  48. Modulation of CD4+ T-Cell Recognition of Influenza Hemagglutinin by Carbohydrate Side Chains Located Outside a T-Cell Determinant

    Article • Virology, January 1993, Elsevier

    Dr Heidi E Drummer

  49. A study of the advantages and limitations of immunoblotting procedures for the detection of antibodies against influenza virus

    Article • Electrophoresis, January 1993, Wiley

    Dr Heidi E Drummer