All Stories

  1. Expansion of artificial intelligence for genome editing

    Article • Nature Structural & Molecular Biology, November 2025, Springer Science + Business Media

    Dr. Heesoo Uhm

  2. AI-generated MLH1 small binder improves prime editing efficiency

    Article • Cell, October 2025, Elsevier

    Dr. Heesoo Uhm

  3. Site-specific replacement of large-scale DNA fragments in human cells

    Article • September 2025, openRxiv

    Dr. Heesoo Uhm

  4. Engineered ADARs enable single-nucleotide resolution DNA A-to-G editing without bystander effects

    Article • August 2025, Springer Science + Business Media

    Dr. Heesoo Uhm

  5. Single-mode termination of phage transcriptions, disclosing bacterial adaptation for facilitated reinitiations

    Article • Nucleic Acids Research, July 2024, Oxford University Press (OUP)

    Dr. Heesoo Uhm, PhD/Prof. Changwon Kang

  6. Rho-dependent transcription termination proceeds via three routes

    Article • Nature Communications, March 2022, Springer Science + Business Media

    Dr. Heesoo Uhm, PhD/Prof. Changwon Kang

  7. RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding

    Article • Nucleic Acids Research, February 2021, Oxford University Press (OUP)

    Dr. Heesoo Uhm

  8. Quantification of purified endogenous miRNAs with high sensitivity and specificity

    Article • Nature Communications, November 2020, Springer Science + Business Media

    Dr. Heesoo Uhm

  9. Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA

    Article • Nature Communications, January 2020, Springer Science + Business Media

    PhD/Prof. Changwon Kang, Dr. Heesoo Uhm

  10. Single-Molecule FRET Assay for Studying Cotranscriptional RNA Folding

    Article • December 2019, Springer Science + Business Media

    Dr. Heesoo Uhm

  11. Multiple RPAs make WRN syndrome protein a superhelicase

    Article • Nucleic Acids Research, April 2018, Oxford University Press (OUP)

    Dr. Heesoo Uhm

  12. Single-molecule FRET studies on the cotranscriptional folding of a thiamine pyrophosphate riboswitch

    Article • Proceedings of the National Academy of Sciences, December 2017, Proceedings of the National Academy of Sciences

    PhD/Prof. Changwon Kang, Dr. Heesoo Uhm

  13. Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors

    Article • Molecular Brain, November 2017, Springer Science + Business Media

    Dr. Heesoo Uhm

  14. Ligand Recognition Mechanism of Thiamine Pyrophosphate Riboswitch Aptamer

    Article • Bulletin of the Korean Chemical Society, November 2017, Wiley

    Dr. Heesoo Uhm

  15. Single-Molecule FRET Combined with Magnetic Tweezers at Low Force Regime

    Article • Bulletin of the Korean Chemical Society, February 2016, Wiley

    Dr. Heesoo Uhm