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  1. Back to the Future—A 50-Year Dive into Embryo Implantation Research: Cell Biological Paradox, Epithelial Cell Polarity, and EMT

    Article • Biomolecules, February 2026, MDPI AG

    Professor Hans-Werner Denker

  2. Embryoids, models, embryos? We need to take a new look at legal norms concerning the beginning of organismic development

    Article • Molecular Human Reproduction, December 2023, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  3. Stem Cell-Derived Organoids, Embryoids, and Embryos: Advances in Organismic Development In Vitro Force Us to Re-Focus on Ethical and Legal Aspects of Model Choice

    Article • Organoids, December 2023, MDPI AG

    Professor Hans-Werner Denker

  4. Twenty years on for The Epithelial-Mesenchymal Transition International Association (TEMTIA): an interview with co-founders Erik Thompson and Donald Newgreen

    Article • Cells Tissues Organs, July 2021, Karger Publishers

    Professor Hans-Werner Denker

  5. Autonomy in the Development of Stem Cell-Derived Embryoids: Sprouting Blastocyst-Like Cysts, and Ethical Implications

    Article • Cells, June 2021, MDPI AG

    Professor Hans-Werner Denker

  6. Rise of the rabbit model for implantation research. A commemoration of the scientific work of Bent G. Boving (1920–2019)

    Article • Biology of Reproduction, March 2020, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  7. Recent embryo twinning data prompt reconsideration of theories on a crucial role of segregation of oocyte cytoplasmic constituents in mammals

    Article • Molecular Human Reproduction, January 2020, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  8. Albrecht Müller, 1959–2019

    Article • Cells Tissues Organs, January 2019, Karger Publishers

    Professor Hans-Werner Denker

  9. Embryonen, Embryoide, Gastruloide ...

    Article • March 2018, Brill Deutschland GmbH

    Professor Hans-Werner Denker

  10. Goodbye and Thank You

    Article • Cells Tissues Organs, January 2018, Karger Publishers

    Professor Hans-Werner Denker

  11. Ronan O’Rahilly 1921–2018: A Personal Remembering

    Article • Cells Tissues Organs, January 2018, Karger Publishers

    Professor Hans-Werner Denker

  12. Self-Organization of Stem Cell Colonies and of Early Mammalian Embryos: Recent Experiments Shed New Light on the Role of Autonomy vs. External Instructions in Basic Body Plan Development

    Article • Cells, October 2016, MDPI AG

    Professor Hans-Werner Denker

  13. Embryo implantation in the uterus: Recent investigations confirming a theory on cellular mechanisms

    Article • American Journal of Reproductive Immunology, October 2016, Wiley

    Professor Hans-Werner Denker

  14. Stem cell potentiality and 'synthetic' embryos

    Article • Cells Tissues Organs, January 2014, Karger Publishers

    Professor Hans-Werner Denker

  15. Comment on G. Herranz: The timing of monozygotic twinning: a criticism of the common model. Zygote (2013)

    Article • Zygote, November 2013, Cambridge University Press

    Professor Hans-Werner Denker

  16. Time to Reconsider Stem Cell Induction Strategies

    Article • Cells, December 2012, MDPI AG

    Professor Hans-Werner Denker

  17. Segregation during cleavage in the mammalian embryo? A critical comparison of whole-mount/CLSM and section immunohistochemistry casts doubts on segregation of axis-relevant leptin domains in the rabbit

    Article • Histochemistry and Cell Biology, May 2011, Springer Science + Business Media

    Professor Hans-Werner Denker

  18. Editorial

    Article • Cells Tissues Organs, January 2011, Karger Publishers

    Professor Hans-Werner Denker

  19. Epithelial–mesenchymal transition in rhesus monkey embryonic stem cell colonies: the role of culturing conditions

    Article • In Vitro Cellular & Developmental Biology, February 2010, Springer Science + Business Media

    Professor Hans-Werner Denker

  20. Editorial

    Article • Cells Tissues Organs, January 2010, Karger Publishers

    Professor Hans-Werner Denker

  21. Editorial

    Article • Cells Tissues Organs, January 2010, Karger Publishers

    Professor Hans-Werner Denker

  22. Editorial

    Article • Cells Tissues Organs, January 2010, Karger Publishers

    Professor Hans-Werner Denker

  23. Ethical concerns over use of new cloning technique in humans

    Article • Nature, September 2009, Springer Science + Business Media

    Professor Hans-Werner Denker

  24. Induced pluripotent stem cells: how to deal with the developmental potential

    Article • Reproductive BioMedicine Online, January 2009, Elsevier

    Professor Hans-Werner Denker

  25. Totipotency/Pluripotency and Patentability

    Article • Stem Cells, June 2008, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  26. Human Embryonic Stem Cells: The Real Challenge for Research as well as for Bioethics Is Still ahead of Us

    Article • Cells Tissues Organs, January 2008, Karger Publishers

    Professor Hans-Werner Denker

  27. Editorial Note

    Article • Cells Tissues Organs, June 2007, Karger Publishers

    Professor Hans-Werner Denker

  28. Epithelial-Mesenchymal Transition in Rhesus Monkey Embryonic Stem Cell Colonies: A Model for Processes Involved in Gastrulation?

    Article • Cells Tissues Organs, January 2007, Karger Publishers

    Professor Hans-Werner Denker

  29. Editorial

    Article • Cells Tissues Organs, January 2007, Karger Publishers

    Professor Hans-Werner Denker

  30. Influences of Extracellular Matrix and of Conditioned Media on Differentiation and Invasiveness of Trophoblast Stem Cells

    Article • Placenta, January 2007, Elsevier

    Professor Hans-Werner Denker

  31. Potentiality of embryonic stem cells: an ethical problem even with alternative stem cell sources

    Article • Journal of Medical Ethics, November 2006, BMJ

    Professor Hans-Werner Denker

  32. Totipotenz - Omnipotenz - Pluripotenz. Ausblendungsphänomene in der Stammzelldebatte: Indikatoren für den Konflikt zwischen Norm- und Nutzenkultur?

    Article • January 2006, De Gruyter

    Professor Hans-Werner Denker

  33. Editorial

    Article • Cells Tissues Organs, January 2006, Karger Publishers

    Professor Hans-Werner Denker

  34. Epithelial–Mesenchymal Transition in Colonies of Rhesus Monkey Embryonic Stem Cells: A Model for Processes Involved in Gastrulation

    Article • Stem Cells, June 2005, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  35. Molecular mechanisms in uterine epithelium during trophoblast binding: the role of small GTPase RhoA in human uterine Ishikawa cells

    Article • Journal of Experimental & Clinical Assisted Reproduction, March 2005, Springer Science + Business Media

    Professor Hans-Werner Denker

  36. Editorial

    Article • Cells Tissues Organs, January 2005, Karger Publishers

    Professor Hans-Werner Denker

  37. Editorial

    Article • Cells Tissues Organs, November 2004, Karger Publishers

    Professor Hans-Werner Denker

  38. Editorial

    Article • Cells Tissues Organs, June 2004, Karger Publishers

    Professor Hans-Werner Denker

  39. II. Berichte

    Article • Jahrbuch für Wissenschaft und Ethik, January 2004, De Gruyter

    Professor Hans-Werner Denker

  40. Early human development: new data raise important embryological and ethical questions relevant for stem cell research

    Article • The Science of Nature, January 2004, Springer Science + Business Media

    Professor Hans-Werner Denker

  41. Role of Collagen Type II and Perlecan in Skeletal Development

    Article • Annals of the New York Academy of Sciences, May 2003, Wiley

    Professor Hans-Werner Denker

  42. Human Uterine Epithelial RL95-2 Cells Reorganize Their Cytoplasmic Architecture with Respect to Rho Protein and F-Actin in Response to Trophoblast Binding

    Article • Cells Tissues Organs, January 2003, Karger Publishers

    Professor Hans-Werner Denker

  43. Endometrial Receptivity: Selective Adhesion Competence of Rabbit Uterine Epithelium for Trophoblast but Not for Various Tumor Cells

    Article • Cells Tissues Organs, January 2003, Karger Publishers

    Professor Hans-Werner Denker

  44. Molecular Approaches to Cell-Cell Adhesion: From Leukocyte Extravasation to Embryo Implantation

    Article • December 2002, Karger Publishers

    Professor Hans-Werner Denker

  45. Adhesiveness of human uterine epithelial RL95-2 cells to trophoblast: Rho protein regulation

    Article • Molecular Human Reproduction, November 2002, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  46. Editorial Note

    Article • Cells Tissues Organs, January 2002, Karger Publishers

    Professor Hans-Werner Denker

  47. Preface

    Article • Cells Tissues Organs, January 2002, Karger Publishers

    Professor Hans-Werner Denker

  48. Experimental Modulation of Cell-Cell Adhesion, Invasiveness and Differentiation in Trophoblast Cells

    Article • Cells Tissues Organs, January 2002, Karger Publishers

    Professor Hans-Werner Denker

  49. In vitro Studies on Endometrial Adhesiveness for Trophoblast: Cellular Dynamics in Uterine Epithelial Cells

    Article • Cells Tissues Organs, January 2002, Karger Publishers

    Professor Hans-Werner Denker

  50. Professor Pietro Motta (1942–2002)

    Article • Cells Tissues Organs, January 2002, Karger Publishers

    Professor Hans-Werner Denker

  51. Editorial

    Article • Cells Tissues Organs, January 2001, Karger Publishers

    Professor Hans-Werner Denker

  52. Calcium influx in human uterine epithelial RL95-2 cells triggers adhesiveness for trophoblast-like cells. Model studies on signalling events during embryo implantation

    Article • Molecular Human Reproduction, December 2000, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  53. Adhesion of trophoblast to uterine epithelium as related to the state of trophoblast differentiation: In vitro studies using cell lines

    Article • Molecular Reproduction and Development, October 2000, Wiley

    Professor Hans-Werner Denker

  54. Adhesion of trophoblast to uterine epithelium as related to the state of trophoblast differentiation: In vitro studies using cell lines

    Article • Molecular Reproduction and Development, January 2000, Wiley

    Professor Hans-Werner Denker

  55. Structural Dynamics and Function of Early Embryonic Coats

    Article • Cells Tissues Organs, January 2000, Karger Publishers

    Professor Hans-Werner Denker

  56. Embryonic Stem Cells: An Exciting Field for Basic Research and Tissue Engineering, but also an Ethical Dilemma?

    Article • Cells Tissues Organs, January 1999, Karger Publishers

    Professor Hans-Werner Denker

  57. Editorial

    Article • Cells Tissues Organs, January 1999, Karger Publishers

    Professor Hans-Werner Denker

  58. Interactions between trophoblast and uterine epithelium: monitoring of adhesive forces

    Article • Human Reproduction, November 1998, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  59. Identification of differentially expressed genes in human trophoblast cells by differential-display RT-PCR

    Article • Placenta, November 1998, Elsevier

    Professor Hans-Werner Denker

  60. Differentiation Markers and Invasiveness: Discordant Regulation in Normal Trophoblast and Choriocarcinoma Cells

    Article • Experimental Cell Research, October 1998, Elsevier

    Professor Hans-Werner Denker

  61. Adhesiveness of the free surface of a human endometrial monolayer for trophoblast as related to actin cytoskeleton

    Article • Molecular Human Reproduction, April 1997, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  62. A Hypermedia Tutorial for Cross-Sectional Anatomy: HyperMed

    Article • Cells Tissues Organs, January 1997, Karger Publishers

    Professor Hans-Werner Denker

  63. Neoglycoprotein-Binding Sites (Endogenous Lectins) in the Fallopian Tube, Uterus and Blastocyst of the Rabbit during the Preimplantation Phase and Implantation

    Article • Cells Tissues Organs, January 1997, Karger Publishers

    Professor Hans-Werner Denker

  64. Editor’s Note

    Article • Cells Tissues Organs, January 1996, Karger Publishers

    Professor Hans-Werner Denker

  65. New Associate Editors

    Article • Cells Tissues Organs, January 1996, Karger Publishers

    Professor Hans-Werner Denker

  66. A novel artificial substrate for cell culture: Effects of substrate flexibility/malleability on cell growth and morphology

    Article • In Vitro Cellular & Developmental Biology, January 1995, Springer Science + Business Media

    Professor Hans-Werner Denker

  67. Differential Expression and Localization of Integrins and CD44 in the Membrane Domains of Human Uterine Epithelial Cells During the Menstrual Cycle

    Article • Cells Tissues Organs, January 1995, Karger Publishers

    Professor Hans-Werner Denker

  68. Differential Expression of CD44 in Rabbit Uterine Epithelium during Early Pregnancy

    Article • Cells Tissues Organs, January 1995, Karger Publishers

    Professor Hans-Werner Denker

  69. Editor’s Note

    Article • Cells Tissues Organs, January 1995, Karger Publishers

    Professor Hans-Werner Denker

  70. The Role of Cell Shape for Differentiation of Choriocarcinoma Cells on Extracellular Matrix

    Article • Experimental Cell Research, November 1994, Elsevier

    Professor Hans-Werner Denker

  71. Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system

    Article • Placenta, June 1994, Elsevier

    Professor Hans-Werner Denker

  72. Cell Biology of Endometrial Receptivity and of Trophoblast-Endometrial Interactions

    Article • January 1994, Springer Science + Business Media

    Professor Hans-Werner Denker

  73. Endometrial receptivity: Cell biological aspects of an unusual epithelium. A review

    Article • Annals of Anatomy - Anatomischer Anzeiger, January 1994, Elsevier

    Professor Hans-Werner Denker

  74. Implantation: A cell biological paradox

    Article • The Journal of Experimental Zoology, September 1993, Wiley

    Professor Hans-Werner Denker

  75. Quantitation of human choriocarcinoma spheroid attachment to uterine epithelial cell monolayers

    Article • June 1993

    Professor Hans-Werner Denker

  76. Differentiation of human trophoblast cells in vitro stimulated by extracellular matrix

    Article • Placenta, January 1993, Elsevier

    Professor Hans-Werner Denker

  77. Retinoic acid decreases attachment of JAR choriocarcinoma spheroids to a human endometrial cell monolayer in vitro

    Article • Placenta, January 1993, Elsevier

    Professor Hans-Werner Denker

  78. Editorial

    Article • Cells Tissues Organs, January 1993, Karger Publishers

    Professor Hans-Werner Denker

  79. Modulation of differentiation markers in human choriocarcinoma cells by extracellular matrix: on the role of a three-dimensional matrix structure

    Article • Differentiation, September 1992, Elsevier

    Professor Hans-Werner Denker

  80. Development of rabbit preimplantation blastocysts cultured with precultured endometrial tissue

    Article • Reproduction, July 1992, Bioscientifica

    Professor Hans-Werner Denker

  81. Endometrial arylamidase activity in the guinea pig: Changes during the oestrous cycle, decidualization and ovarian steroid hormone treatment

    Article • Comparative Biochemistry and Physiology Part B Comparative Biochemistry, January 1991, Elsevier

    Professor Hans-Werner Denker

  82. The dynamic structure of rabbit blastocyst coverings

    Article • Brain Structure and Function, January 1991, Springer Science + Business Media

    Professor Hans-Werner Denker

  83. Trophoblast Invasion and Endometrial Receptivity

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  84. Changes of Intermediate Filament Protein Localization in Endometrial Cells During Early Pregnancy of Rabbits

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  85. A Three-Dimensional Organ Culture Model for the Study of Implantation of Rabbit Blastocyst In Vitro

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  86. Changes in Lectin Binding Patterns in Rabbit Endometrium During Pseudopregnancy, Early Pregnancy and Implantation

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  87. Changes in Lipid Organization of Uterine Epithelial Cell Membranes at Implantation in the Rabbit

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  88. Choriocarcinoma Cell Spheroids: An In Vitro Model for the Human Trophoblast

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  89. Penetration of the Basal Lamina by Processes of the Uterine Epithelial Cells during Implantation in the Rabbit

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  90. Preparation of Rabbit Uterine Epithelium for Trophoblast Attachment: Histochemical Changes in the Apical and Lateral Membrane Compartment

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  91. Trophoblast - Endometrial Interactions at Embryo Implantation: A Cell Biological Paradox

    Article • January 1990, Springer Science + Business Media

    Professor Hans-Werner Denker

  92. Rabbit endometrium in organ culture: Morphological evidence for progestational differentiation in vitro

    Article • Cell and Tissue Research, September 1989, Springer Science + Business Media

    Professor Hans-Werner Denker

  93. The dynamic structure of rabbit blastocyst coverings

    Article • Brain Structure and Function, November 1988, Springer Science + Business Media

    Professor Hans-Werner Denker

  94. Implantation-induced changes in uterine arylamidase localization in the rabbit, rat, hamster and guinea-pig

    Article • Reproduction, May 1988, Bioscientifica

    Professor Hans-Werner Denker

  95. Gap junction formation in rabbit uterine epithelium in response to embryo recognition

    Article • Developmental Biology, March 1988, Elsevier

    Professor Hans-Werner Denker

  96. Changes in Intraconceptus Pressure in the Rabbit during Days 7-10 of Pregnancy1

    Article • Biology of Reproduction, April 1987, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  97. Apical plasma membrane-bound enzymes of rabbit uterine epithelium

    Article • Histochemistry and Cell Biology, January 1987, Springer Science + Business Media

    Professor Hans-Werner Denker

  98. Embryo implantation and proteinase activities in a marsupial (Macropus eugenii)

    Article • Cell and Tissue Research, November 1986, Springer Science + Business Media

    Professor Hans-Werner Denker

  99. A sensitive assay for proteolytic activity using fluorescein-labeled gelatin coupled to Sepharose 4B as substrate

    Article • Analytical Biochemistry, January 1986, Elsevier

    Professor Hans-Werner Denker

  100. Partial Purification and Characterization of a Trypsin-Like Proteinase from Rabbit Preimplantation Uterine Fluid

    Article • Biological Chemistry Hoppe-Seyler, January 1985, De Gruyter

    Professor Hans-Werner Denker

  101. The Role of Blastolemmase in Implantation Initiation in the Rabbit

    Article • January 1981, Springer Science + Business Media

    Professor Hans-Werner Denker

  102. Embryo Implantation and Trophoblast Invasion

    Article • January 1980, Elsevier

    Professor Hans-Werner Denker

  103. Enzymic Characterization of Rabbit Blastocyst Proteinase with Synthetic Substrates of Trypsin-Like Enzymes

    Article • Hoppe-Seyler´s Zeitschrift für physiologische Chemie, January 1979, De Gruyter

    Professor Hans-Werner Denker

  104. The dynamic structure of rabbit blastocyst coverings

    Article • Brain Structure and Function, January 1979, Springer Science + Business Media

    Professor Hans-Werner Denker

  105. Studies on the early development and implantation in the cat

    Article • Brain Structure and Function, January 1978, Springer Science + Business Media

    Professor Hans-Werner Denker

  106. Implantation

    Article • January 1977, Springer Science + Business Media

    Professor Hans-Werner Denker

  107. Introduction

    Article • January 1977, Springer Science + Business Media

    Professor Hans-Werner Denker

  108. Discussion

    Article • January 1977, Springer Science + Business Media

    Professor Hans-Werner Denker

  109. Materials and Methods

    Article • January 1977, Springer Science + Business Media

    Professor Hans-Werner Denker

  110. Summary

    Article • January 1977, Springer Science + Business Media

    Professor Hans-Werner Denker

  111. Results

    Article • January 1977, Springer Science + Business Media

    Professor Hans-Werner Denker

  112. Copper IUD-Induced Loss of Endometrial Arylamidase Activity in the Rabbit

    Article • Biology of Reproduction, November 1976, Oxford University Press (OUP)

    Professor Hans-Werner Denker

  113. EFFECT OF THE BLASTOCYST ON A UTERINE AMINO ACID ARYLAMIDASE IN THE RABBIT

    Article • Reproduction, November 1975, Bioscientifica

    Professor Hans-Werner Denker

  114. Protease substrate film test

    Article • Histochemistry and Cell Biology, January 1974, Springer Science + Business Media

    Professor Hans-Werner Denker

  115. Note to the paper: Protease substrate film test [Histochemistry 38, 331?338 (1974)]

    Article • Histochemistry and Cell Biology, January 1974, Springer Science + Business Media

    Professor Hans-Werner Denker

  116. Enzym-Topochemie von Fr�hentwicklung und Implantation des Kaninchens

    Article • Histochemistry and Cell Biology, January 1971, Springer Science + Business Media

    Professor Hans-Werner Denker

  117. Enzym-Topochemie von Fr�hentwicklung und Implantation des Kaninchens

    Article • Histochemistry and Cell Biology, January 1971, Springer Science + Business Media

    Professor Hans-Werner Denker

  118. Enzym-Topochemie von Fr�hentwicklung und Implantation des Kaninchens

    Article • Histochemistry and Cell Biology, January 1971, Springer Science + Business Media

    Professor Hans-Werner Denker

  119. Artefakte im Amylase-Substratfilmtest

    Article • Histochemistry and Cell Biology, January 1970, Springer Science + Business Media

    Professor Hans-Werner Denker