All Stories

  1. Interplay Between Dysregulated Immune System and the Footprints of Blood-Borne miRNAs in Treatment Naive Crohn’s Disease and Ulcerative Colitis Patients
  2. Adipokines as Prognostic Biomarkers in Multiple Myeloma: A Case–Control Study
  3. Comparison of the Effect of CFTR Modulators elexacaftor/tezacaftor/ivacaftor and lumacaftor/ivacaftor via Serum Human Epididymis Protein 4 Concentration in p.Phe508del-CFTR Homozygous Cystic Fibrosis Patients
  4. Cvill6 and Cvill7: Potent and Selective Peptide Blockers of Kv1.2 Ion Channel Isolated from Mexican Scorpion Centruroides villegasi
  5. Look Beyond Plasma Membrane Biophysics: Revealing Considerable Variability of the Dipole Potential Between Plasma and Organelle Membranes of Living Cells
  6. Inhibition of K+ Channels Affects the Target Cell Killing Potential of CAR T Cells
  7. Novel insights into the modulation of the voltage-gated potassium channel KV1.3 activation gating by membrane ceramides
  8. A synthetic flavonoid derivate in the plasma membrane transforms the voltage‐clamp fluorometry signal of CiHv1
  9. Activity of Potassium Channels in CD8+ T Lymphocytes: Diagnostic and Prognostic Biomarker in Ovarian Cancer?
  10. Introducing NZ-58, a potent inhibitor of the human voltage-gated proton channel
  11. Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni
  12. Of Seven New K+ Channel Inhibitor Peptides of Centruroides bonito, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2
  13. Effect of the Lipid Landscape on the Efficacy of Cell-Penetrating Peptides
  14. Molecular rearrangements in S6 during slow inactivation in Shaker-IR potassium channels
  15. 5-Chloro-2-Guanidinobenzimidazole (ClGBI) Is a Non-Selective Inhibitor of the Human HV1 Channel
  16. The Voltage-Gated Hv1 H+ Channel Is Expressed in Tumor-Infiltrating Myeloid-Derived Suppressor Cells
  17. Characterization and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K+ Channel KV1.2 and Small- and Intermediate-Conductance Ca2+-Activated K+ Channels KCa2.2 and KCa3.1
  18. Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?
  19. Recombinant Expression in Pichia pastoris System of Three Potent Kv1.3 Channel Blockers: Vm24, Anuroctoxin, and Ts6
  20. Effects of One-Year Tofacitinib Therapy on Lipids and Adipokines in Association with Vascular Pathophysiology in Rheumatoid Arthritis
  21. The hEag1 K+ Channel Inhibitor Astemizole Stimulates Ca2+ Deposition in SaOS-2 and MG-63 Osteosarcoma Cultures
  22. Cm28, a scorpion toxin having a unique primary structure, inhibits KV1.2 and KV1.3 with high affinity
  23. sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity
  24. Role of C-Terminal Domain and Membrane Potential in the Mobility of Kv1.3 Channels in Immune Synapse Forming T Cells
  25. Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles
  26. Peptide Inhibitors of Kv1.5: An Option for the Treatment of Atrial Fibrillation
  27. Cyclodextrins Exert a Ligand-like Current Inhibitory Effect on the KV1.3 Ion Channel Independent of Membrane Cholesterol Extraction
  28. Immune Synapse Residency of Orai1 Alters Ca2+ Response of T Cells
  29. Optimization of Pichia pastoris Expression System for High-Level Production of Margatoxin
  30. KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology
  31. A disulfide-stabilised helical hairpin fold in acrorhagin I: An emerging structural motif in peptide toxins
  32. Shaker-IR K+ channel gating in heavy water: Role of structural water molecules in inactivation
  33. Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells
  34. The Kv1.3 K+ channel in the immune system and its “precision pharmacology” using peptide toxins
  35. Immunomagnetic separation is a suitable method for electrophysiology and ion channel pharmacology studies on T cells
  36. Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels
  37. The activation gate controls steady-state inactivation and recovery from inactivation in Shaker
  38. The voltage-gated proton channel hHv1 is functionally expressed in human chorion-derived mesenchymal stem cells
  39. Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom
  40. Weaponisation ‘on the fly’: Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies
  41. Periodic Membrane Potential and Ca2+ Oscillations in T Cells Forming an Immune Synapse
  42. N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis
  43. Pore-modulating toxins exploit inherent slow inactivation to block K + channels
  44. Determining the target of membrane sterols on voltage-gated potassium channels
  45. Selective Na V 1.1 activation rescues Dravet syndrome mice from seizures and premature death
  46. Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT fold
  47. Membrane Potential Distinctly Modulates Mobility and Signaling of IL-2 and IL-15 Receptors in T Cells
  48. The C-terminal HRET sequence of Kv1.3 regulates gating rather than targeting of Kv1.3 to the plasma membrane
  49. Pi5 and Pi6, two undescribed peptides from the venom of the scorpion Pandinus imperator and their effects on K + -channels
  50. Optimization of the Synthesis of Flavone–Amino Acid and Flavone–Dipeptide Hybrids via Buchwald–Hartwig Reaction
  51. A new mechanism of voltage-dependent gating exposed by KV10.1 channels interrupted between voltage sensor and pore
  52. Sterol Regulation of Voltage-Gated K+ Channels
  53. Closed-state inactivation involving an internal gate in Kv4.1 channels modulates pore blockade by intracellular quaternary ammonium ions
  54. 7DHC-induced changes of Kv1.3 operation contributes to modified T cell function in Smith-Lemli-Opitz syndrome
  55. Erratum to: Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes
  56. Isolation, chemical and functional characterization of several new K+-channel blocking peptides from the venom of the scorpion Centruroides tecomanus
  57. Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes
  58. The anti-proliferative effect of cation channel blockers in T lymphocytes depends on the strength of mitogenic stimulation
  59. Probing pattern and dynamics of disulfide bridges using synthesis and NMR of an ion channel blocker peptide toxin with multiple diselenide bonds
  60. An engineered scorpion toxin analogue with improved Kv1.3 selectivity displays reduced conformational flexibility
  61. Mesenchymal Stromal Cell-Like Cells Set the Balance of Stimulatory and Inhibitory Signals in Monocyte-Derived Dendritic Cells
  62. Margatoxin is a non-selective inhibitor of human Kv1.3 K+ channels
  63. Structure, Molecular Modeling, and Function of the Novel Potassium Channel Blocker Urotoxin Isolated from the Venom of the Australian Scorpion Urodacus yaschenkoi
  64. Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Signalling Exerts Chondrogenesis Promoting and Protecting Effects: Implication of Calcineurin as a Downstream Target
  65. Ion channels and anti-cancer immunity
  66. OcyKTx2, a new K+-channel toxin characterized from the venom of the scorpion Opisthacanthus cayaporum
  67. The role of PSD-95 in the rearrangement of Kv1.3 channels to the immunological synapse
  68. Transient receptor potential vanilloid‐2 mediates the effects of transient heat shock on endocytosis of human monocyte‐derived dendritic cells
  69. Analysis of the K+ current in human CD4+ T lymphocytes in hypercholesterolemic state
  70. Membrane microdomain organization, calcium signal, and NFAT activation as an important axis in polarized Th cell function
  71. Vm24, a Natural Immunosuppressive Peptide, Potently and Selectively Blocks Kv1.3 Potassium Channels of Human T Cells
  72. Structure, Function, and Chemical Synthesis of Vaejovis mexicanus Peptide 24: A Novel Potent Blocker of Kv1.3 Potassium Channels of Human T Lymphocytes
  73. Switch of Voltage-Gated K+ Channel Expression in the Plasma Membrane of Chondrogenic Cells Affects Cytosolic Ca2+-Oscillations and Cartilage Formation
  74. Voltage-Gated Sodium Channel Nav1.7 Maintains the Membrane Potential and Regulates the Activation and Chemokine-Induced Migration of a Monocyte-Derived Dendritic Cell Subset
  75. Intact rat superior mesenteric artery endothelium is an electrical syncytium and expresses strong inward rectifier K+ conductance
  76. Effects of the PKC inhibitors chelerythrine and bisindolylmaleimide I (GF 109203X) on delayed rectifier K+ currents
  77. Ion channels in T lymphocytes: An update on facts, mechanisms and therapeutic targeting in autoimmune diseases
  78. Answer to the “Comment on functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse” by Stefan Bittner et al. [Immunol. Lett. 125 (Aug 15 (2)) (2009) 156–157]
  79. Developmental Switch of the Expression of Ion Channels in Human Dendritic Cells
  80. Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus
  81. Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse
  82. Potassium channel expression in human CD4+ regulatory and naïve T cells from healthy subjects and multiple sclerosis patients
  83. Special Issue from the International Conference on Molecular Recognition, Pécs; and Regional Biophysics Meeting, Balatonfüred; August 2007
  84. A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus
  85. IV. International conference on molecular recognition
  86. Effects of changes in extracellular pH and potassium concentration on Kv1.3 inactivation
  87. Involvement of Membrane Channels in Autoimmune Disorders
  88. Nutrition and immune system: Certain fatty acids differently modify membrane composition and consequently kinetics of KV1.3 channels of human peripheral lymphocytes
  89. Probing the Cavity of the Slow Inactivated Conformation of Shaker Potassium Channels
  90. Cross Talk between Activation and Slow Inactivation Gates of Shaker Potassium Channels
  91. Changes in Purinoceptor Distribution and Intracellular Calcium Levels following Noise Exposure in the Outer Hair Cells of the Guinea Pig
  92. K+ Channel Blockers: Novel Tools to Inhibit T Cell Activation Leading to Specific Immunosuppression
  93. Death or survival: Membrane ceramide controls the fate and activation of antigen-specific T-cells depending on signal strength and duration
  94. Differential expression of potassium currents in Deiters cells of the guinea pig cochlea
  95. Novel α-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells
  96. The EBSA prize lecture
  97. Anuroctoxin, a New Scorpion Toxin of the α-KTx 6 Subfamily, Is Highly Selective for Kv1.3 over IKCa1 Ion Channels of Human T Lymphocytes
  98. Regulation of the lateral wall stiffness by acetylcholine and GABA in the outer hair cells of the guinea pig
  99. Looking through ion channels: recharged concepts in T-cell signaling
  100. Differential expression of purinergic receptor subtypes in the outer hair cells of the guinea pig
  101. An Alternative to Conventional Immunosuppression: Small-Molecule Inhibitors of Kv1.3 Channels
  102. pH-dependent modulation of Kv1.3 inactivation: role of His399
  103. Ion channels and lymphocyte activation
  104. New phenotypic, functional and electrophysiological characteristics of KG-1 cells
  105. Kv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cells
  106. Active and passive behaviour in the regulation of stiffness of the lateral wall in outer hair cells of the guinea-pig
  107. Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K channel
  108. Cholesterol modifies the gating of Kv1.3 in human T lymphocytes
  109. Colocalization and nonrandom distribution of Kv1.3 potassium channels and CD3 molecules in the plasma membrane of human T lymphocytes
  110. Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K+-channels with distinctly different affinities
  111. Multiple Binding Sites for Melatonin on Kv1.3
  112. Effects of Toxins Pi2 and Pi3 on Human T Lymphocyte Kv1.3 Channels: The Role of Glu7 and Lys24
  113. Blockage of Human T Lymphocyte Kv1.3 Channels by Pi1, a Novel Class of Scorpion Toxin
  114. Pandinus imperatorScorpion Venom Blocks Voltage-Gated K+Channels in Human Lymphocytes
  115. Immunosuppressors Inhibit Voltage-Gated Potassium Channels in Human Peripheral Blood Lymphocytes
  116. Assembly and suppression of endogenous Kv1.3 channels in human T cells.
  117. C-type inactivation of a voltage-gated K+ channel occurs by a cooperative mechanism
  118. Plasma-membrane-Bound mcromoleculas are dynamically aggregated to form non-random codistribution patterns of selected functional elements. Do pattern recognition processes govern antigen presentation and intercellular interactions?
  119. Ion-channel activities regulate transmembrane signaling in thymocyte apoptosis and T-cell activation
  120. Peripheral Blood Lymphocytes Display Reduced K+ Channel Activity in Aged Humans
  121. A Ca2+-dependent K+-channel in freshly isolated and cultured chick osteoclasts
  122. Biphasic Effect of Extracellular ATP on the Membrane Potential of Mouse Thymocytes
  123. Effect of cyclosporin A on the membrane potential and Ca2+ level of human lymphoid cell lines and mouse thymocytes