All Stories

  1. Discovery of Potential GSK-3β Allosteric Modulators for Alzheimer’s Disease

    Article • March 2023, American Chemical Society (ACS)

    Guilherme Martins Silva

  2. Novel Pharmacokinetics Profiler (PhaKinPro): Model Development, Validation, and Implementation as a Web-Tool for Triaging Compounds with Undesired PK Profiles

    Article • March 2023, American Chemical Society (ACS)

    Guilherme Martins Silva

  3. Ligand-based virtual screening, molecular dynamics, and biological evaluation of repurposed drugs as inhibitors of Trypanosoma cruzi proteasome

    Article • Journal of Biomolecular Structure and Dynamics, February 2023, Taylor & Francis

    Guilherme Martins Silva

  4. Pharmacophore-based virtual screening from phytocannabinoids as antagonist r-CB1

    Article • Journal of Molecular Modeling, August 2022, Springer Science + Business Media

    Guilherme Martins Silva, Henrique Lima

  5. Hierarchical Virtual Screening Based on Rocaglamide Derivatives to Discover New Potential Anti-Skin Cancer Agents

    Article • Frontiers in Molecular Biosciences, June 2022, Frontiers

    Guilherme Martins Silva

  6. Chromatographic profile, in silico and in vivo study of the pharmacokinetic and toxicological properties of major constituent present in kefir, the kefiran

    Article • Toxicology Research, May 2022, Oxford University Press (OUP)

    Guilherme Martins Silva, Henrique Lima

  7. Advances in Computational Techniques for Discovery and Development of Drugs Against Leishmaniasis, a Brief Review

    Article • January 2022, Springer Science + Business Media

    Guilherme Martins Silva

  8. Lead Optimization in Drug Discovery

    Article • January 2022, Springer Science + Business Media

    Guilherme Martins Silva

  9. Structural Aspects of Organic Compounds as Proteasome Inhibitors Addressed to Several Diseases

    Article • January 2022, Springer Science + Business Media

    Guilherme Martins Silva

  10. Potential colchicine binding site inhibitors unraveled by virtual screening, molecular dynamics and MM/PBSA

    Article • Computers in Biology and Medicine, October 2021, Elsevier

    Guilherme Martins Silva

  11. Synthesis, antitumor activity and in silico analyses of amino acid derivatives of artepillin C, drupanin and baccharin from green propolis

    Article • Bioorganic & Medicinal Chemistry, October 2021, Elsevier

    Guilherme Martins Silva

  12. Revisiting the Proposition of Binding Pockets and Bioactive Poses for GSK-3β Allosteric Modulators Addressed to Neurodegenerative Diseases

    Article • International Journal of Molecular Sciences, July 2021, MDPI AG

    Guilherme Martins Silva

  13. Identification of known drugs with potential to treat COVID-19

    Article • Future Medicinal Chemistry, June 2021, Future Science

    Guilherme Martins Silva

  14. Reviewing computational toxicology, methodologies and software

    Article • January 2021, Springer Science + Business Media

    Guilherme Martins Silva

  15. Key Aspects for Achieving Hits by Virtual Screening Studies

    Article • January 2021, Springer Science + Business Media

    Guilherme Martins Silva

  16. Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer therapy using ligand and structure-based virtual screening

    Article • International Journal of Biological Macromolecules, December 2020, Elsevier

    Guilherme Martins Silva

  17. Proposition of Potential GSK-3β Inhibitors for the Treatment of Alzheimer’s Disease: A Molecular Modeling Study

    Article • Current Computer - Aided Drug Design, November 2020, Bentham Science Publishers

    Guilherme Martins Silva

  18. Theoretical Study of Monoamine Oxidase B Inhibitors as Drug Candidates for Treatment of Parkinson’s Disease

    Article • Central Nervous System Agents in Medicinal Chemistry, September 2020, Bentham Science Publishers

    Guilherme Martins Silva

  19. Molecular Docking, Physicochemical Properties, Pharmacokinetics and Toxicity of Flavonoids Present in Euterpe Oleracea Martius

    Article • Current Computer - Aided Drug Design, June 2020, Bentham Science Publishers

    Guilherme Martins Silva

  20. Overview of existing allosteric modulators related to Alzheimer's disease

    Article • ChemMedChem, August 2019, Wiley

    Guilherme Martins Silva