All Stories

  1. Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer

    Article • International Journal of Molecular Sciences, December 2018, MDPI AG

    Guido Keijzers

  2. A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome

    Article • Genetics in Medicine, December 2018, Springer Science + Business Media

    Guido Keijzers

  3. Monogenic Diseases of DNA Repair

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, February 2018, New England Journal of Medicine (NEJM/MMS)

    Guido Keijzers

  4. Genetic Diseases in DNA-Repair Pathways

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, November 2017, New England Journal of Medicine (NEJM/MMS)

    Guido Keijzers

  5. Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro

    Article • Nucleic Acids Research, July 2017, Oxford University Press (OUP)

    Guido Keijzers

  6. DNA mismatch repair and its many roles in eukaryotic cells

    Article • Mutation Research/Reviews in Mutation Research, July 2017, Elsevier

    Guido Keijzers

  7. Exonuclease 1 and its versatile roles in DNA repair

    Article • Critical Reviews in Biochemistry and Molecular Biology, August 2016, Taylor & Francis

    Guido Keijzers

  8. RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks

    Article • Cell Reports, June 2016, Elsevier

    Guido Keijzers

  9. The Ku70 80 ring in Non-Homologous End-Joining easy to slip on hard to remove

    Article • Frontiers in Bioscience, January 2016, Frontiers in Bioscience

    Guido Keijzers

  10. Ku70 and Ku80

    Article • January 2016, Springer Science + Business Media

    Guido Keijzers

  11. EXO1 (Exonuclease 1)

    Article • January 2016, Springer Science + Business Media

    Guido Keijzers

  12. Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

    Article • Mitochondrion, November 2015, Elsevier

    Guido Keijzers

  13. Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients

    Article • Aging, October 2015, Impact Journals, LLC

    Guido Keijzers

  14. Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures

    Article • Bioscience Reports, April 2015, Portland Press Ltd.

    Guido Keijzers

  15. The role of RecQ helicases in non-homologous end-joining

    Article • Critical Reviews in Biochemistry and Molecular Biology, July 2014, Taylor & Francis

    Guido Keijzers

  16. RECQ helicase RECQL4 participates in non-homologous end joining and interacts with the Ku complex

    Article • Carcinogenesis, June 2014, Oxford University Press (OUP)

    Guido Keijzers

  17. Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

    Article • DNA Repair, April 2014, Elsevier

    Guido Keijzers

  18. Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity

    Article • Mechanisms of Ageing and Development, January 2014, Elsevier

    Guido Keijzers

  19. Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells

    Article • Aging, November 2013, Impact Journals, LLC

    Guido Keijzers

  20. Modulation of DNA base excision repair during neuronal differentiation

    Article • Neurobiology of Aging, July 2013, Elsevier

    Guido Keijzers

  21. The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients

    Article • Aging, December 2012, Impact Journals, LLC

    Guido Keijzers

  22. 14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Article • DNA Repair, March 2012, Elsevier

    Guido Keijzers

  23. Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks

    Article • DNA Repair, January 2011, Elsevier

    Guido Keijzers

  24. DNA Repair and the Accumulation of Oxidatively Damaged DNA Are Affected by Fruit Intake in Mice

    Article • The Journals of Gerontology Series A, September 2010, Oxford University Press (OUP)

    Guido Keijzers

  25. Evidence that OGG1 Glycosylase Protects Neurons against Oxidative DNA Damage and Cell Death under Ischemic Conditions

    Article • Journal of Cerebral Blood Flow & Metabolism, August 2010, SAGE Publications

    Guido Keijzers

  26. Neurons Efficiently Repair Glutamate-induced Oxidative DNA Damage by a Process Involving CREB-mediated Up-regulation of Apurinic Endonuclease 1

    Article • Journal of Biological Chemistry, June 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Guido Keijzers

  27. A mouse model for chronic lymphocytic leukemia based on expression of the SV40 large T antigen

    Article • Blood, March 2009, American Society of Hematology

    Guido Keijzers

  28. The Ku80 Carboxy Terminus Stimulates Joining and Artemis-Mediated Processing of DNA Ends

    Article • Molecular and Cellular Biology, December 2008, ASM Journals

    Guido Keijzers

  29. Establishment of a root proteome reference map for the model legumeMedicago truncatulausing the expressed sequence tag database for peptide mass fingerprinting

    Article • PROTEOMICS, November 2001, Wiley

    Guido Keijzers

  30. Establishment of a root proteome reference map for the model legume Medicago truncatula using the expressed sequence tag database for peptide mass fingerprinting

    Article • PROTEOMICS, November 2001, Wiley

    Guido Keijzers