All Stories

  1. Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson’s Disease Cell Models

    Article • Oxidative Medicine and Cellular Longevity, October 2019, Hindawi Publishing Corporation

    Guey-Jen Lee-Chen

  2. Indole Compound NC009-1 Augments APOE and TRKA in Alzheimer’s Disease Cell and Mouse Models for Neuroprotection and Cognitive Improvement

    Article • Journal of Alzheimer s Disease, January 2019, IOS Press

    Guey-Jen Lee-Chen

  3. Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation

    Article • Oxidative Medicine and Cellular Longevity, October 2018, Hindawi Publishing Corporation

    Ming-Chung Lee, Guey-Jen Lee-Chen

  4. Novel synthetic chalcone-coumarin hybrid for Aβ aggregation reduction, antioxidation, and neuroprotection

    Article • CNS Neuroscience & Therapeutics, September 2018, Wiley

    Guey-Jen Lee-Chen

  5. Tau Misfolding Reduction by Enhancement of HSPB1

    Article • CNS Neuroscience & Therapeutics, July 2016, Wiley

    Guey-Jen Lee-Chen

  6. Treatment with a Ginkgo biloba extract, EGb 761, inhibits excitotoxicity in an animal model of spinocerebellar ataxia type 17

    Article • Drug Design Development and Therapy, February 2016, Dove Medical Press

    Guey-Jen Lee-Chen, Professor Chung-Hsin Wu

  7. The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

    Article • Drug Design Development and Therapy, February 2016, Dove Medical Press

    Guey-Jen Lee-Chen

  8. Protein kinase Cη polymorphism and the susceptibility to ischemic stroke in the Taiwan population

    Article • Biomedical Journal, January 2015, Elsevier

    Guey-Jen Lee-Chen

  9. Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models

    Article • Drug Design Development and Therapy, October 2014, Dove Medical Press

    Dr Donala Janreddy, Pin-Jui Kung, Guey-Jen Lee-Chen, 育晨 陶, Professor Chung-Hsin Wu