All Stories

  1. Recent advancements in tissue dissociation techniques for cell manufacturing single-cell analysis and downstream processing
  2. AAV delivers as a lingering guest, not an invader
  3. Trial offers hope to children with hypoplastic left heart syndrome
  4. Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity
  5. Acceptability of prenatal diagnosis and prenatal treatment of haemophilia using cell and gene therapies within US haemophilia community
  6. Functional characterization of the immunomodulatory properties of human urine-derived stem cells
  7. Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A
  8. A new “FIX” for hemophilia B gene therapy
  9. Microfluidic devices for studying coagulation biology
  10. Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A
  11. Fetal and Maternal Safety Considerations for In Utero Therapy Clinical Trials: iFeTiS Consensus Statement
  12. Gene and Stem Cell Therapies for Fetal Care
  13. Defining the Optimal FVIII Transgene for Placental Cell-Based Gene Therapy to Treat Hemophilia A
  14. Soluble Fas affects erythropoiesis in vitro and acts as a potential predictor of erythropoiesis-stimulating agent therapy in patients with chronic kidney disease
  15. Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery
  16. Tissue engineering and transplantation in the fetus
  17. Mechanistic Insights into Factor VIII Immune Tolerance Induction via Prenatal Cell Therapy in Hemophilia A
  18. In Memoriam: A Tribute to Esmail Zanjani, 1938–2019
  19. Deconstructed Microfluidic Bone Marrow On‐A‐Chip to Study Normal and Malignant Hemopoietic Cell–Niche Interactions
  20. Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation
  21. In Utero Gene Therapy Consensus Statement from the IFeTIS
  22. Targeting Mesenchymal Stromal Cells/Pericytes (MSCs) With Pulsed Electromagnetic Field (PEMF) Has the Potential to Treat Rheumatoid Arthritis
  23. Peripheral Blood Stem Cells
  24. Prenatal Cell- and Gene-Based Therapies for Regenerative Medicine
  25. Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning
  26. Mesenchymal stem cells in myeloproliferative disorders – focus on primary myelofibrosis
  27. Exposure of the Bone Marrow Microenvironment to Simulated Solar and Galactic Cosmic Radiation Induces Biological Bystander Effects on Human Hematopoiesis
  28. Microgravity Impairs DNA Damage Repair in Human Hematopoietic Stem/Progenitor Cells and Inhibits Their Differentiation into Dendritic Cells
  29. Bone marrow cell response after injury and during early stage of regeneration is independent of the tissue‐of‐injury in 2 injury models
  30. Correction: A human bone marrow mesodermal-derived cell population with hemogenic potential
  31. Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer
  32. Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments
  33. A human bone marrow mesodermal-derived cell population with hemogenic potential
  34. Evaluation of Cytotoxic and Genotoxic Effects of Extremely Low-frequency Electromagnetic Field on Mesenchymal Stromal Cells
  35. Umbilical Cord Blood Expansion as an Alternate Graft Source for HSC Transplantation
  36. Das westliche Havelland – eine Charakteristik
  37. In vitro and in vivo assessment of direct effects of simulated solar and galactic cosmic radiation on human hematopoietic stem/progenitor cells
  38. Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation
  39. The hematopoietic system in the context of regenerative medicine
  40. Treating Hemophilia by Gene Therapy
  41. Fetal Therapies and Maternal-Fetal Tolerance
  42. In utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical application
  43. Defining Engraftment Patterns and Interactions Between Hematopoietic Stem Cells and Stromal Cells after in Utero Transplantation
  44. The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation
  45. Consensus statement from the first international conference for in utero stem cell transplantation and gene therapy
  46. Hematopoiesis in Regenerative Medicine
  47. Sheep CD34+ Amniotic Fluid Cells Have Hematopoietic Potential and Engraft After Autologous In Utero Transplantation
  48. Hemophilia A: an ideal disease to correct in utero
  49. Perivascular Stromal Cells as a Potential Reservoir of Human Cytomegalovirus
  50. Temporal definition of haematopoietic stem cell niches in a large animal model ofin uterostem cell transplantation
  51. Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells
  52. Optimization Of Vascular Niches To Increase Hematopoietic Engraftment
  53. RUNX1C-Mediated Reprogramming Of Human Bone Marrow Stromal Cells into Early Blood Progenitors
  54. CD166+CD34+ Cells Exhibit Marked Functional Differences During Fetal and Adult Life
  55. Gene Therapy: The Promise of a Permanent Cure
  56. 13 Mesenchymal stem cells as therapeutics for liver repair and regeneration
  57. Characterization of Naturally-Occurring Humoral Immunity to AAV in Sheep
  58. Regenerative medicine: prospects for the treatment of inflammatory bowel disease
  59. Mesenchymal Stem Cells Engineered to Inhibit Complement-Mediated Damage
  60. EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool
  61. Mesenchymal stem cells contribute to endogenous FVIII:c production
  62. HCMV Protein LUNA Is Required for Viral Reactivation from Latently Infected Primary CD14+ Cells
  63. Defining the Potential of MSCs with a Prenatal Large Animal Model
  64. Origin and Characterization of CD166+ Cells During Human Marrow Ontogeny
  65. Mesenchymal Stem Cells Engineered to Inhibit Complement-Mediated Damage
  66. Identification and Phenotypic Characterization of a Subpopulation of Acute Myelogenous Leukemia (AML) Cells with Increased Plastic Adherence.
  67. Niche Perivascular Stromal Cells As a Potential Reservoir and a Source of HCMV Reactivation
  68. Development and Characterization of Recombinant Ovine Coagulation Factor VIII
  69. Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model
  70. Modulation of Human Mesenchymal Stem Cell Immunogenicity through Forced Expression of Human Cytomegalovirus US Proteins
  71. Expression levels of the PiT‐2 receptor explain, in part, the gestational age‐dependent alterations in transduction efficiency after in utero retroviral‐mediated gene transfer
  72. Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC
  73. Development and Characterization of Recombinant Ovine Factor VIII
  74. Fetal Gene Therapy
  75. Initial CD34+ cell‐enrichment of cord blood determines hematopoietic stem/progenitor cell yield upon Ex vivo expansion
  76. Characterization and Functionality of Cardiac Progenitor Cells in Congenital Heart Patients
  77. Integration pattern of HIV-1 based lentiviral vector carrying recombinant coagulation factor VIII in Sk-Hep and 293T cells
  78. Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery
  79. Stem cell gene manipulation and delivery as systemic therapeutics
  80. Bone marrow stem cells and liver regeneration
  81. In vivo generation of β-cell–like cells from CD34+ cells differentiated from human embryonic stem cells
  82. Persistent circulating human insulin in sheep transplanted in utero with human mesenchymal stem cells
  83. Bioactivity of immobilized EGF on self‐assembled monolayers: Optimization of the immobilization process
  84. Clinical and molecular characterization of a re‐established line of sheep exhibiting hemophilia A
  85. Dynamic cell-cell interactions between cord blood haematopoietic progenitors and the cellular niche are essential for the expansion of CD34+, CD34+CD38−and early lymphoid CD7+cells
  86. Systematic delineation of optimal cytokine concentrations to expand hematopoietic stem/progenitor cells in co-culture with mesenchymal stem cells
  87. Induction of notch signaling by immobilization of jagged-1 on self-assembled monolayers
  88. Characterization of the Human Hematopoietic Niche During Ontogeny.
  89. Defining the Development of Receptive Niches for in Utero Transplantation of Hematopoietic Stem Cells.
  90. Generation of Functional Humanized Liver in Sheep by Bone Marrow Cells
  91. Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics
  92. Factors Determining the Risk of Inadvertent Retroviral Transduction of Male Germ Cells After In Utero Gene Transfer in Sheep
  93. Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer
  94. Docosahexanoic acid induces dose dependent cell death in an early undifferentiated subtype of acute myeloid leukemia cell line
  95. The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers
  96. Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells
  97. A Frame Shift-Induced Stop Codon Causes Hemophilia a in Sheep.
  98. Modulation of Mesenchymal Stem Cell Immunogenicity through Forced Expression of Human Cytomegalovirus Proteins
  99. Tales from the Crypt: Mesenchymal Stem Cells for Replenishing the Intestinal Stem Cell Pool
  100. Early fetal gene delivery utilizes both central and peripheral mechanisms of tolerance induction
  101. Generation of functional natural killer and dendritic cells in a human stromal-based serum-free culture system designed for cord blood expansion
  102. Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep
  103. The human–sheep chimeras as a model for human stem cell mobilization and evaluation of hematopoietic grafts' potential
  104. A Stro-1+ human universal stromal feeder layer to expand/maintain human bone marrow hematopoietic stem/progenitor cells in a serum-free culture system
  105. Adult Mesenchymal Stem Cells: A Pluripotent Population with Multiple Applications
  106. The time course of engraftment of human mesenchymal stem cells in fetal heart demonstrates that Purkinje fiber aggregates derive from a single cell and not multi-cell homing
  107. Kinetic Analysis of the ex vivo Expansion of Human Hematopoietic Stem/Progenitor Cells
  108. Reduced Stem Cell Factor Links Smooth Myopathy and Loss of Interstitial Cells of Cajal in Murine Diabetic Gastroparesis
  109. Proteomic Analysis Reveals Intrinsic Differences between Phenotypically Identical Mesenchymal Stem Cells.
  110. Male Germ-Line Cells Are at Risk Following Direct-Injection Retroviral-Mediated Gene Transfer in Utero
  111. A human stromal-based serum-free culture system supports the ex vivo expansion/maintenance of bone marrow and cord blood hematopoietic stem/progenitor cells
  112. In vivo haematopoietic potential of human neural stem cells
  113. Gestational age of recipient determines pattern and level of transgene expression following in utero retroviral gene transfer
  114. Formation of human hepatocytes by human hematopoietic stem cells in sheep
  115. A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation Potential
  116. CORRIGENDUM
  117. Human Mesenchymal Stem Cells Form Purkinje Fibers in Fetal Sheep Heart
  118. Purification of interstitial cells of Cajal by fluorescence-activated cell sorting
  119. Human haematopoietic stem cells that mediate long‐term in vivo engraftment are not susceptible to infection by human cytomegalovirus
  120. The Fetal Sheep: A Unique Model System for Assessing the Full Differentiative Potential of Human Stem Cells
  121. A large animal noninjury model for study of human stem cell plasticity
  122. Plasticity of Human Stem Cells in the Fetal Sheep Model of Human Stem Cell Transplantation
  123. The Sheep Model of in utero Gene Therapy
  124. Modelling of ex vivo expansion/maintenance of hematopoietic stem cells
  125. Hematopoietic stem cells: from the bone to the bioreactor
  126. Reversible expression of CD34 by adult human bone marrow long-term engrafting hematopoietic stem cells
  127. Differentiative potential of human metanephric mesenchymal cells
  128. Human natural killer cell development in a xenogeneic culture system
  129. Ex vivo expanded cord blood cells provide rapid engraftment in fetal sheep but lack long-term engrafting potential
  130. Transduction of Long-Term-Engrafting Human Hematopoietic Stem Cells by Retroviral Vectors
  131. Induction of stable prenatal tolerance to β-galactosidase by in utero gene transfer into preimmune sheep fetuses
  132. The Monoclonal Antibody W7C5 Defines a Novel Surface Antigen on Hematopoietic Stem Cells
  133. Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system
  134. Adult Stem Cell Plasticity and Methods of Detection
  135. Evaluation of Serum-Free Culture Conditions Able to Support the Ex Vivo Expansion and Engraftment of Human Hematopoietic Stem Cells in the Human-to-Sheep Xenograft Model
  136. Kinetics of engraftment of CD34− and CD34+ cells from mobilized blood differs from that of CD34− and CD34+ cells from bone marrow
  137. Human/Sheep Hematopoietic Chimeras
  138. Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation
  139. In utero transfer and expression of exogenous genes in sheep
  140. Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero
  141. Homing of Human Cells in the Fetal Sheep Model: Modulation by Antibodies Activating or Inhibiting Very Late Activation Antigen-4–Dependent Function
  142. Engraftment and Multilineage Expression of Human Bone Marrow CD34− Cells In Vivoa
  143. Plasmodium-falciparum-infected erythrocytes adhere to immortalized human bone marrow endothelial cells
  144. Human Thymic Stroma Supports Human Natural Killer (NK) Cell Development from Immature Progenitors
  145. Engraftment of Cultured Human Hematopoietic Cells in Sheep
  146. Definition of Early Progenitors and Functional Maturation of Human Natural Killer Cells: Requirements for Cytocidal Activity
  147. AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells
  148. Transplantation of hematopoietic stem cells in utero
  149. Treatment of X-Linked Severe Combined Immunodeficiency by in Utero Transplantation of Paternal Bone Marrow
  150. Isolation, characterization, and biologic features of bone marrow endothelial cells
  151. THE ROLE OF SHEEP STROMA IN HUMAN HAEMOPOIESIS IN THE HUMAN/SHEEP CHIMAERAS
  152. Cytomegalovirus as a Cause of Pancytopenia
  153. Retention and multilineage expression of human hematopoietic stem cells in human‐sheep chimeras
  154. Human cytomegalovirus alters interleukin-6 production by endothelial cells
  155. Human cytomegalovirus alters interleukin-6 production by endothelial cells